A patient diagnosed with Peripheral T cell NHL in the year 2014. Location of the infected lymph node was Right Gorin, which enlarged to lower abdomen. Peripheral T cell NHL digonosed after excision biopsy. She got 7 Cycle CHOP and Radiotherapy. In September 2020 a PET-CT Scan done after she notice sever itching problem. PET scan showed an 70x51x70mm sized Anterior Mediastinal Mass with SUV max 11. Thoracic surgeon refused to operate the mass. A core biopsy and histochemestry done few days ago. Which shows an Intermediate grade Diffuse large B cell Lymphoma. CD20, BCL6 & MUM1 are positive. BCL2, CD3, CD5 & CD10 Negative. Bone marrow aspiration suggesting "Reactive marrow with myeloid hyperplasia and excess of lymphocytes". Before all these diagnosis the patient only faced itching problem. First symptom noticed on the beginning of August 2020. Last 24-26th October the patient suddenly faced swallowing face. An echocardiogram of the heart on 27th October showing small amount of fluid buildup around her heart. LDH lifted to 366. Her oncologists immediately suggest chemotherapy. The new chemo protocol is R-GCEOP. 1st Cycle started on 27th October and splited into 3 days. Rithuximab, Cyclophosphamide, Gemcitabine, Etopside, Vincristine, prednisone given. After 1st cycle chemo, face swallowing and itching removed significantly. Do you think the new protocol of chemotherapy is good for the patient? And is it possible that, a patient treated previously with T cell Lymphoma will affected newly by DLBCL? Is chemotherapy alone is good option to remove the DLBCL? If remove with chemo further Stem cell transplantation is necessary? Her current age 32 years.

Just wondering if you need radiotherapy for gastric Lymphoma after RCHOP 6 cycles and PET CT is negative. Will appreciate your view.

I waS Prescribed R-CHOP for a small-cell refractory (3) N-H Lymphoma, I thought that was a over kill(too toxic for my age (72 yo), now after being refused a COVID-19 test prior to Chemo, I am here wondering if that was a right move any suggestions...