What is MTHFR? Explained simply by Dr. Ben Lynch

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What is MTHFR? Explained simply by Dr. Ben Lynch

Рет қаралды 5,264

Күн бұрын

Discussing What is MTHFR in my recent podcast with Karalynne Call @just.ingredients.podcast
MTHFR is one gene out of 18,000 genes in your body.
It's an incredibly important one as it is in charge of producing your body's main form of folate called 5-methyltetrahydrofolate also known as L-methylfolate or 5-MTHF.
Like to learn more about MTHFR and 6 other incredibly important genes? Read Dr. Lynch's book, Dirty Genes:
amzn.to/3TQh1yI
StrateGene Report:
Interpret your MTHFR variations, and over 100 genetic variations over 9 different pathways using your 23andme, Ancestry or SelfDecode raw data
www.seekinghea...
SHEI Membership: Monthly live calls with Dr. Lynch along with 100+ hours of Dr. Lynch’s conferences on genetics and epigenetics
www.seekinghea...
Instagram:
@DrBenLynch
0:00 - 0:58 - Introduction
0:59 - 2:30 - What is MTHFR?
2:31 - 3:34 - MTHFR’s job
3:35 - 5:21 - Treatment & Results
5:22 - 6:10 - Example & Outro

Пікірлер: 66

@tinad6812 4 ай бұрын

Dr. Ben, your voice is so needed out there. People need to know the specifics for them individually, instead of guessing and taking random supplements. Happy to see you. 😊

@DrBenLynch 4 ай бұрын

Thank you ;)

@MissInfinity 4 ай бұрын

Glad you're back posting videos!

@DrBenLynch 4 ай бұрын

Me too!

@mattoltman7122 3 ай бұрын

Dr. Lynch, my wife has just found out she is homozygous 677 and your videos have been invaluable helping us understand what it means, how it can influence health, and how to move forward without being terrified. Thank you so much.

@theshawnhunter 4 ай бұрын

Thank you for this and all of your new videos🙏🏻

@sawdustadikt979 3 ай бұрын

Glad to see you are back. About a year ago, through the guidance of a naturopath and a dietitian I went through some of the most intense and bizarre symptoms I had ever experienced when treating me for severe psoriasis. I couldn’t work, barely preform house chores or go out anywhere, my symptoms were all neurological and debilitating(vertigo where I couldn’t stand up, migraines with fevers, all day panic attacks, heart arrhythmias, involuntary eye movements, stiff neck, stomach so tight I couldn’t stand up straight, shooting pain down my arms, drop foot, slurred speech, severe depression, invasive voices and hallucinations). They were perplexed and all they could say was that I was under to much stress. The shortest version of this was that I figured out on my own that I was having brain swelling and neurological inflammation as well as being on way to much methyl folate, b-6 and glycine. As well as being severely b-1 deficient. Reading your book and the comments on your videos helped a lot as well as finding Elliot Overton.

@DrBenLynch 3 ай бұрын

well done. you are not alone in this. So many people are over supplementing those nutrients - big time. Glad you figured it out.

@christineschroeder4509 4 ай бұрын

Thank you Dr Ben!!! You have helped me so much!!!

@DrBenLynch 4 ай бұрын

Happy to help!

@shaku55 4 ай бұрын

I love your book, and your information about methylfolate has been super helpful. Life changing even. Have you ever weighed in on B one deficiencies? I would be interested to hear your thoughts on how what effects a high carb diet and resulting B1 deficiency would have on someone who had a MTHFR mutation. Or even just your thoughts on how a MTHFR mutation might suggest a need to check for a B1 deficiency.

@g.s.5868 4 ай бұрын

that is dr berg and some other dude thing.... vit B1 ... due to carb overload

@shaku55 4 ай бұрын

@@g.s.5868 Sure, I've watched hours of videos by Elliot Overton. And Dr. Berg is no slouch either, but Elliot is the resident expert on mega dosing B1 IMHO. But Dr Lynch's work on Methylfolate has changed my life. Heck, his sublingual B12/L-Methylfolate supplement is the only one that works for me, for some reason my GI doesn't absorb it properly when taken orally. TMI! But combining a B1 megadose protocol with managing Methylfolate levels and removing almost all carbs and seed oils from my diet has taken life up a HUGE notch, I feel like a normal person again. And yet I can't find anyone talking about both of these vitamins in conjunction. There must be other people who need both besides me. Just curious if Dr. Lynch has thoughts about this, or maybe him and Elliot could do a podcast together sometime and talk through any interconnections.

@DrBenLynch 4 ай бұрын

B1 is an incredibly important vitamin associated with so many things - more than metabolism. Aldehyde breakdown is a big one. I use a significant amount of B1 in my formulations. I even use TPP, the body's most active form of thiamine, in our Brain Nutrients Lozenge. That supplement hits your brain in seconds. I agree that B1 needs more love and attention. I do plan on getting my podcast off the ground here soon, too. I'll look up Elliot Overton. www.seekinghealth.com/products/brain-nutrients

@katrinagrubner4263 4 ай бұрын

So our govt has mandated synthetic folic acid in all our bread products. Won’t this play havoc for people with the MTHR gene ?

@dayoffnow 4 ай бұрын

@katrinagrubner4263 Yes.

@DrBenLynch 4 ай бұрын

It will, and currently does, wreak havoc in everyone - regardless if one has a MTHFR defect or not. Folic acid contributes to EPIGENETIC issues regardless of what SNPs you have or don't have. Folic acid must be avoided by everyone - and use natural folates found in liver, leafy green vegetables, supplement with folinic acid and/or methylfolate.

@katrinagrubner4263 4 ай бұрын

@@DrBenLynch Thank you. I thought as much (in my layperson simplistic way). Gosh it’s almost like they’re TRYING to make us sick. Fluoride in the water etc . Grrr.

@manuelhsu1756 13 күн бұрын

Dr. Lynch, could you tell me if excess tetrahydrofolate that is not methylated can be diverted towards de novo synthesis of uric acid and increase its production? Thank you😊

@VedaSay 4 ай бұрын

Our genes are only suggestive. Which path is taken to produce a particular protein depends on our over all health and actually the chemical state of the body.

@DrBenLynch 4 ай бұрын

Our genes are rigid in how they are coded. They are not rigid in how they are expressed. We control their expression for the most part. Not all of them - hair color is set as is skin color. But most of our genetic expression is controlled by our actions - and lack of actions.

@techniranjan9312 2 ай бұрын

I have detected MTHFR gene c.1286A>C and Six month ago I have greater than 50 homosystein so that time I have CVST problem but now I am totally fine now But doctor told me you have to take anticoagulant life long what can i do sir is is right or wrong to do life long

@g.s.5868 4 ай бұрын

ah nice, you are back with some videos....where have you been? enjoying riches from books and your website ?

@DrBenLynch 4 ай бұрын

missed you too.

@ashley5627 4 ай бұрын

@@DrBenLynchI hope you're enjoying any & all benefits from your books & website. Thank you for all of it! I thought I was a psychotic person until I learned I had several mutations & lots of blood work over the years to understand how it all works. Still learning, working towards balance but you cracked that open for me. Couldn't be more grateful. Thank you.

@1aliveandwell 3 ай бұрын

Tried creatine but just got headaches. (PC helped tho feel improved some). HCy lab was good( 8 ), did fine having children , but tried folica acid 1 time and next day had horid painful tongue that read was from low B12 (sores over entire thing), did try tiny bit once of MFolate but couldnt stay awake for hrs, so stopped that. Do recall when 5 grabbing liver and eating it and tasted so good, so must have been low in iron, B's... B2 does help ability to think ! A Rhuem was going to test me for antiphopholipid ( read many people have trouble of miscarries with that) (got chilblains in winter (in So Cal !)). So does eating greens/veggies supply us with enuf Mfolate?? Is there a lab for that? My folate labs in 20's. B12 labs are not reliable as mine is high ,but read analyzers often use anitbodies and if you have those ab then results incorrect. Do have 667T Homo.

@hacksawe 3 ай бұрын

I have the c677T gene variant but I feel worse (increased anxiety) when I take a B complex any ideas?

@OrthoMoon 4 ай бұрын

I had a gene test done it said MTHFR C677T: C/T A1298C: A/A [Intermediate activity] is this bad

@DrBenLynch 4 ай бұрын

The genetic test identified that you have 1 variant in the 677 area of your MTHFR gene. This reduces your MTHFR enzyme's ability to perform by about 20% or so. Is it bad? No. It's important to understand and be mindful of. Read Dirty Genes - highly recommended place to start. amzn.to/3U0tujv

@OrthoMoon 4 ай бұрын

@@DrBenLynch I also have COMT Val/val

@N17sd 4 ай бұрын

Hi Doctor, could u explain when do we use the supplement of yours : B Minus ? I have MTHFR issues and my B12 is high without supplementing , plus high Homocysteine. I heard u start with B minus then u add Folate. Can u elaborate on this? Thank you so much

@DrBenLynch 4 ай бұрын

You use B Minus if you find that folate and B12 are too much for you - causing side effects like anxiety, headaches, insomnia, irritability, joint pain or acne to name a few. You can have B12 without supplementing from your microbiome - and may be a sign of SIBO. It may also be a sign that you are low in glutathione and/or methylfolate. I'd consider Homocysteine Nutrients to support healthy levels of homocysteine. www.seekinghealth.com/products/homocysteine-nutrients You would take this once in the morning. Then check your homocysteine in a week or two in a fasted state in the morning.

@N17sd 4 ай бұрын

@@DrBenLynch thank you Doctor ❤ So I did a serum blood work , all B vitamins r within the norm and glutathione is high 😬 …I know serum is not accurate. Anyhow, I am waiting for the SIBO results. So I will start on homocysteine support . Sorry what’s the difference between this supplement and methylated B complex? Thank you again and God bless you doctor. Btw I love how in your book ( Dirty Genes) you wrote it as if you are talking directly to us …is of course the invaluable information.

@iah8331 3 ай бұрын

I have mthfr. I’ve had pain in my liver for about 15 years, same amount of time I’ve had hashimotos. I’ve had ultrasound, CT, MRI, blood tests. The results have been all over the place, from all normal blood work and nothing showing up on scans. Then fatty liver showed up Then it went away Then liver enzymes skyrocketed And my liver showed scarring with a stiffness score of 2. Now my enzymes are back to normal. Not sure if my liver is still scarred without another scan. For the past two days my liver hurts more than it’s ever hurt before. Drs can’t do anything for me, cause they don’t really have an answer. What do I do ? What does my poor liver need ? I’m afraid I’m going to end up with cirrhosis. Thank you

@laldave 3 ай бұрын

Look up anti inflammatory diets and how to reverse fatty liver… research on NAC, and other natural supplements to support this efforts , look Into drinking lemon water in the mornings if this doesn’t go against your health conditions, you will have to cut off processed foods, sugars chocolate diary etc and lastly , look Into frequency medicine, I use AO scan and it’s helped me a lot! Take care of your body, love yourself more everyday, go for walks , baths , run away from cortisol , I wish you the best ❤🙏 oh yeah make sure you ask your doctor about any changes or supplements that may work best for you ❤

@laldave 3 ай бұрын

Also check out Glutathione

@iah8331 3 ай бұрын

@@laldave I’ve taken so much glutathione, I’m not sure it really does anything for me. Every Integrative Dr tells me to take it and I do, but nothing improves

@GhostOfRT300 4 ай бұрын

MTHFR is actually an enzyme, and it acts on the MTHFR gene. Right?

@DrBenLynch 4 ай бұрын

MTHFR gene produces the MTHFR enzyme. The MTHFR enzyme is the one that has the altered function if a SNP is present in the MTHFR gene.

@kellygolemba3033 4 ай бұрын

Another thing…. My daughter has a double mutation and suffers horribly with OCD…we have done so much and still can’t get it under control…. The MTHFR gene is hell!

@ethimself5064 4 ай бұрын

Methylated B Vitamins are the answer

@hexchad765 4 ай бұрын

I am the same as your daughter. I struggled tremendously as a young person. I came out the other side. She can too. This guy has the right ideas. Follow his diet suggestions. You can get her to capitalize on the OCD. For example, she'd make a fantastic engineer or some other hobby where it's a positive. Visual art. Music. It will get better

@ethimself5064 4 ай бұрын

@@hexchad765 Read the other reply

@g.s.5868 4 ай бұрын

my daughter went from OCD to health worry OCD... now living with my ex that does not believe or give a crap about genes, supplements that can help...

@hexchad765 4 ай бұрын

@@ethimself5064 it's only the answer sometimes, my friend, and is only one of many dietary suggestions one must take

@ToddDouglasFox 4 ай бұрын

We have a lot of say about how our bodies function but keep in mind Ben that more than a trillion actions will have occurred in the time it takes you to read this comment. We know almost nothing as pertains to each action, including our rudimentary understanding of the body. The cells were deciding without our choices in utero (in terms of diet, hydration, thought process, etc.), and it’s basically no different after birth and throughout our lifetimes. Mostly we should not get in the body’s way. There are times it goes rogue but rather than think of that as the body being dumb, it’s we who don’t get it (until and if we do). A better way to explain our impact is that our bodies need us to make good decisions and making good decisions requires working in tandem with how the body really works, not just a few ideas science and medicine and wellness posits about it. There is much to grasp about KNOWING the body we live in. That is where the wisdom surpasses the ideas but doesn’t exclude them.

@DrBenLynch 4 ай бұрын

Yep. Key is to learn as much how our body works - and wants to work. Then we nurture it so it can perform to the best possible. This is my point behind the concept of 'Dirty Genes'. We're the ones messing up how our body works - not the other way around.

@ToddDouglasFox 4 ай бұрын

@@DrBenLynch We can think only so much and then everything else, which is of the greatest consequence, has to do with truly learning the nuanced language of the body. We work with a lot of patients who are trying to listen and sense but as a result of humans having lost so much wisdom in the past few hundred years, it is exceedingly difficult. The toxic load we each carry due to what we put into food, soil, air and water is the bane of tuning in effectively. But as we do this collaboration together, we improve in our felt sense and intuition and genteel wisdom as to what our predecessors knew off the cuff.

@rudystudios 4 ай бұрын

👏👏

@mariadoyle8264 4 ай бұрын

Did this get cut off short ?

@GhostOfRT300 4 ай бұрын

Yes it did, intentionally I believe. That snipped was shown to simply explain the MTHFR gene. 👍🏼

@g.s.5868 4 ай бұрын

pay for full version ?@@GhostOfRT300

@DrBenLynch 4 ай бұрын

I cut it short yes. You may listen to the full interview on the Just Ingredients Podcast ;)

@Nancie550 4 ай бұрын

Why is your shoulder smoking?…I’m so distracted.

@dilettanter 4 ай бұрын

That’s hilarious - i wen’t to check and saw it!

@LindaHadley 4 ай бұрын

@@dilettanter I can see it too. So weird.

@truthfreed7 4 ай бұрын

Likely a humidifier

@DrBenLynch 4 ай бұрын

I have a humidifier in my office. Humidity in my office is 28% unless I have it going. I set it to 50%. You want interior humidity around 40% to 50% for lung health. :)

@dilettanter 4 ай бұрын

Mystery solved!!! Thanks for the lung heatlh info :)@@DrBenLynch