I had Long Covid and Post Vac and started to suffer from a lot of pain in my feet and legs. I woke up every morning with shooting pains in my feet and legs. In the internet I learned about Alpha Lipoic Acid and ordered it. In the beginning I took 500 mg three times a day, and within one week the pain was gone ! Blood circulation which was poor before also improved greatly, and an inflammation in my leg also disappeared. I am 76 years old and not diabetic. I am continuing with 500 mg two times a day.

Need help with onset falling

Had emergency spine surgery over fours ago due to damaged spine cauda equine.have numb foot burning some ankle swelling can't move toes because of nerve damage after surgery.lucky I can walk but no feeling in foot

I've had CIDP for 6 years, so I'm very familiar with peripheral neuropathy. I do IVIG, and wear brace on left leg. Biggest issue I have is burning on bottom of feet. I refuse Lyrica and Gabepentin...no way. Been on Trazadone, worked for a bit. Now my neuro has me on Amitriptlyne. It's getting worse in my right hand, it's always very cold...2 middle fingers in particular.

thank you

I have a burning electric sensation in my chest and abdomin area. About 40 or so years ago I had shingles. That is what it feels like. Very painful. I use kratom to help manage the pain but not working very well lately. Pain getting worse. Diagnosed with type 1 diabetes several years ago. Use Lantus for insulin and Lyrica to help with pain. Getting fearful about this.

I was diagnosed in 1999 with idiopathic peripheral neuropathy. Again in 2012. I was also diagnosed with diabetes Type 2 in 2014 (provoked through Spiricort given to suppress symptoms of Polymyalgia Rheumatica) and had a heart attack in 2019. For neuropathic pain relief I was started on Gabapentin and Cymbalta. Because of horrid cognitive side effects, Cymbalta was switched out for Effexor. Unfortunately, these cognitive side effects didn't stop, so I stopped using them. Since about 2015 I've been taking INSTEAD of the Cymbalta/Effexor & Gabapentin (as it stands 25. Nov. 2023): R-Lipoic Acid 300 (240) mg - 1-1-1-1 Acetyl-L-Carnitine 750 mg - 1-1-0-1 N-Acetyl Cysteine (NAC) 1000 mg - 1-0-1-0 Omega 3 (fish oil) 1000 mg - 1-0-1-0 Borage Oil 1000 mg (GLA = Gamma Linolenic Acid) - 1-1-1-0 (stopped 1. nov. 2023) Magnesium 100 mg - 1-1-1-1 These above have helped some. I came to use these through exclusionary processes. IOW, I'd take a substance for a while, noting sensations. Then I'd stop and see what happens. These above “passed” this exclusionary process. If I noticed an increase in severity of symptoms when stopping a substance, I could conclude, that it was actually helpful when I was taking it. I then added Benfotiamine starting on 15.08.2023. Helped greatly, most overt pain gone, but numbness still prevalent (time of writing 22.12.2023). Some stomach ache if dosage is over 150mg, so I take 100/150mg 1-1-0-0 / 150mg 0-0-1-0 and 250mg before going to bed (0-0-0-1) - I don't get stomach ache before going to sleep or during the night. I then added on September 5, 2023 (as it stands 25. Nov. 2023): Folic acid 1.7 mg 1-1-1-0 Biotin 5 mg 1-0-0-0 Methylcobalamin 1500 mcg 1-1-1-0 Vitamin B6 P5P 27mg 1-1-0-0 The 4 above plus Benfotiamine & R-Lipoic acid, according to this study, which has been cited many times in meta studies concerning use of supplements to treat neuropathy pain: Maladkar, M., Tekchandani, C. and Dave, U. (2014) Post-Marketing Surveillance of Fixed Dose Combination of Methylcobalamin, Alpha Lipoic Acid, Folic Acid, Biotin, Benfotiamine & Vitamin B6-Nutripathy for the Management of Peripheral Neuropathy. Journal of Diabetes Mellitus, 4, 124-132. dx.doi.org/10.4236/jdm.2014.42019 www.scirp.org/journal/paperinformation.aspx?paperid=46105 “Results: Treatment led to significant reduction from baseline score in various neuropathy symptoms from the 4th week itself. After 12 weeks of treatment, the mean pain score declined by 78.0%, numbness by 92.1% and muscle weakness by 96.9%. Also, there was 96.0% & 99.2% reduction in tingling & burning sensation respectively. No serious adverse events were reported. Conclusion: The current study confirms that fixed dose combination of Methylcobalamin, ALA, Folic Acid, Biotin, Benfotiamine & Vitamin B6 is effective & well tolerated in the management of peripheral neuropathy.” “This PMS included 497 patients with peripheral neuropathy and was conducted at 5 different centers by qualified investigators. The efficacy of the treatment was assessed based on improvement in parameters like neuropathic pain, numbness, muscle weakness, tingling and burning. Investigation of parameters was performed throughout the treatment period on: visit I (baseline), visit II (week 4), visit III (week 8) and visit IV (week 12).” “Patients with peripheral neuropathy were orally administered fixed dose combination of Methylcobalamin 1500 mcg, ALA 200 mg, folic acid 5 mg, biotin 5 mg, Benfotiamine 50 mg & vitamin B6 5 mg once daily for 12 weeks.” Hakim, M., Kurniani, N., Pinzon, R. T., Tugasworo, D., Basuki, M., Haddani, H., Pambudi, P., Fithrie, A., & Wuysang, A. D. (2018). Management of peripheral neuropathy symptoms with a fixed dose combination of high-dose vitamin B1, B6 and B12: A 12-week prospective non-interventional study in Indonesia. Asian Journal of Medical Sciences, 9(1), 32-40. doi.org/10.3126/ajms.v9i1.18510 nepjol.info/index.php/AJMS/article/view/18510 Baltrusch, Simone (2021) The role of Neurotropic B Vitamins in Nerve Regeneration, Biomed Res Int. 2021; 2021: 9968228. Published online 2021 Jul 13. doi: 10.1155/2021/9968228 www.hindawi.com/journals/bmri/2021/9968228/ Pinzon RT, Schellack N, Matawaran BJ, et al. (2023) Clinical Recommendations for the use of Neurotropic B vitamins (B1, B6, and B12) for the Management of Peripheral Neuropathy: Consensus from a Multidisciplinary Expert Panel. J Assoc Physicians India 2023;71(7):93-98. www.japi.org/y26464c4/clinical-recommendations-for-the-use-of-neurotropic-b-vitamins-b1-b6-and-b12-for-the-management-of-peripheral-neuropathy-consensus-from-a-multidisciplinary-expert-panel Silviana, Meyvita, Tugasworo, Dodik, Belladonna,Maria (2020) The Efficacy of Vitamin B1, B6, and B12 Forte Therapy in Peripheral Neuropathy Patients, DOI: doi.org/10.14710/dimj.v2i1.9549 Geller M, Oliveira L, Nigri R, Mezitis SG, Ribeiro MG, et al. (2017) B Vitamins for Neuropathy and Neuropathic Pain. Vitam Miner 6: 161. www.hilarispublisher.com/open-access/b-vitamins-for-neuropathy-and-neuropathic-pain-2376-1318-1000161.pdf Amorin Remus Popa, Simona Bungau, Cosmin MihaiI Vesa, Andrei Cristian Bondar, Carmen Pantis, Octavian Machiar, Ioana Alina DimulescuI, Delia Carmen Nistor Cseppento, Marius Rus, (2019) Evaluating the Efficacy of the Treatment with Benfotiamine and Alpha-lipoic Acid in Distal Symmetric Painful Diabetic Polyneuropathy, Revista de Chimie, Buchares, Original Edition- 70(9) DOI:10.37358/RC.19.9.7498, www.researchgate.net/publication/336529734_Evaluating_the_Efficacy_of_the_Treatment_with_Benfotiamine_and_Alpha-lipoic_Acid_in_Distal_Symmetric_Painful_Diabetic_Polyneuropathy H. Stracke, W. Gaus, U. Achenbach, K. Federlin, R.G. Bretzel, (2008) Benfotiamine in Diabetic Polyneuropathy (BENDIP): Results of a Randomised, Double Blind, Placebo- controlled Clinical Study, 2008 Nov;116(10):600-5. doi: 10.1055/s-2008-1065351. Epub 2008 May 13. pubmed.ncbi.nlm.nih.gov/18473286/ Carlos-Alberto Calderon-Ospina, Mauricio Orlando Nava-Mesa & Ana María Paez-Hurtado (2020) Update on Safety Profiles of Vitamins B1, B6, and B12: A Narrative Review, Therapeutics and Clinical Risk Management, 16:, 1275-1288, DOI: 10.2147/TCRM.S274122 www.tandfonline.com/doi/full/10.2147/TCRM.S274122

I'm a diabetic and I am also suffering from neurological problems under my feet most especially at night. What supplements should I take help me? I live in west Africa in Liberia. Liberia

I have had five back surgeries developed arachnoiditis, neuropathy legs/feet, carpal tunnel, ulnar compression, trigeminal neuralgia and intercostal neuralgia! But why?

My problem is that my left foot hurts , it starts with the 2 last baby toes, shoots down the outside of my foot and goes all around the Ankle bone, then it goes to half of my food and a little on my heel. What should I do ????

My foot feels like it has a lump in the heel. No numbness. It hurts to stand on my feet when I wake up in the morning. I had a car accident and this started after.

Does acupuncture help ??

Can lymphadema cause neuropathy?

It definitely has something to do with the back.

I got neuropathy, degenerative disc disease osteoarthritis so you guys aren't helping me