My son's epilepsy medications over the years have freaked people out. Diazepam for emergencies, but people presume I'm taking it, not that it's for a child. Sodium Valproic, I've had people assume it's a supplement or some sort of essential oil that I give my kid. So when I've said it's important my child gets his meds, I've had people roll their eyes. I'm not an overprotective mother. If he doesn't take his meds, he'll have seizures. I hate how people jump to conclusions. Some day, he's going to be a young man having seizures alone in public and I've heard from other people with epilepsy is people assume they're drug addicts and are slow to help.
@joylox2 жыл бұрын
I have ADHD and chronic pain and have people say similar stuff. Which makes it even harder because I have pretty bad luck with medications, from side effects, to losing effectiveness, to just not doing what they should. So many people have told me to just walk more, or just take B12, but that's not the issue at all, and even doctors dismiss me. It's unfortunate because if something helps and isn't causing side effects, why not take it? I'd be happy to have anything to make my life less of a daily struggle.
@KOKO-uu7yd2 жыл бұрын
Oh holy hell!! My mother had epilepsy. It is SO FRUSTRATING, the challenges and balancing act patients can face! By any chance, does your children's hospital (or whatever facility you work with) have some sort of advocate, or something similar? That person may have experience working with or persuading "lunk-headed" individuals. They may be able to offer you tips and tricks etc, even if they usually can't directly help? 🤞🤞🤞💞💞💞💞
@runningfromabear83542 жыл бұрын
@@KOKO-uu7yd I just work with his pediatric-neurologist. I can handle it, it's just people being a nuisance.
@Brett_S_420 Жыл бұрын
Try cbd or even thc.
@harmonicaveronica Жыл бұрын
Does he have a medical alert bracelet? I had a coworker who wore one and I never looked very close or asked because I figured it was none of my business as long as she was fine. It may be helpful if he has a seizure without you around at some point - even if a bystander didn't notice it, a paramedic would
@TICKLEMEPINK4516 жыл бұрын
I take spironolactone and I have to explain to every concerned new nurse I see that its for hormonal acne, not hypertension.
@BandanaDrummer955 жыл бұрын
Just gotta love that fake mint taste
@KnakuanaRka5 жыл бұрын
Why would the nurses be concerned about you taking medicine for hypertension?
@alexwang9825 жыл бұрын
What is it supposed for
@Wasabi_Tears5 жыл бұрын
Try explaining to each new doctor that your spironolactone isn't for high blood pressure, your metformin isn't for diabetes, and your propranolol isn't for hypertension. That's a real field day.
@Anna-tc6rz5 жыл бұрын
@@KnakuanaRka I assume because in her pic she looks rather young. Young bp problems are never good
@ArizonaJewell3 жыл бұрын
Gabapentin is another interesting case. It was originally designed as a muscle relaxant, but these days it's used to treat nerve pain and seizures. There's also a lot of recent evidence supporting its use in treating anxiety, as well as sleep. I take it every night and it does wonders for anxiety-related insomnia.
@fiction-6 жыл бұрын
Before I watch: I take Prasosin, a blood pressure medication that surprised doctors when it became apparent that people with severe PTSD who took it just stopped having nightmares. I also take hydroxychloroquine, a malaria medication. I dont have malaria but I do have sjogrens and RA.
@letitiajeavons63333 жыл бұрын
You're a patient who's supposed to take hydroxychloroquine because you have an autoimmune condition.
@x_Woozy6 жыл бұрын
You should do an episode on medications we use but don't exactly know how they work
@LivvyBooks6 жыл бұрын
Michael is such a nice host to watch and listen to!
@angi77176 жыл бұрын
Allyvia F I definitely enjoy watching him
@andi52625 жыл бұрын
Mmmhmm!
@Chris-ue8zl4 жыл бұрын
Bold of you to assume I’m a lady
@karga90143 жыл бұрын
He is cute
@virglibrsaglove3 жыл бұрын
Yep. Three years later he still is.
@chronicallyfabulous886 жыл бұрын
My flatmate started taking Propranolol for severe Generalised Anxiety Disorder and OMFG, the improvements for him have been genuinely life-changing 😊 After about 2yrs of taking it every day, his anxiety has even improved without it in his system, which makes me wonder whether perhaps there's a kind of reconditioning of the brain going on, over the long-term?
@MmeHyraelle6 жыл бұрын
I wish some doc RX me this one then. Still haven't found a molecule that works. Except seroquel brain smasher/zombifier.
@IceMetalPunk6 жыл бұрын
I once took a drug psychology course at uni. The way my professor described it, therapy does the most work, but for many patients, they are too affected to actually stick to the therapy. The meds can help them enough for the therapy to "get through to them", and once the therapy starts working, you can wean off the meds without reverting back. At least, that's the goal. But everyone's different, and some people will always need the meds to stay in control.
@chronicallyfabulous886 жыл бұрын
IceMetalPunk Yeah, in my flatmate's case, he wasn't able to afford to see a psychologist (Australia's public health system doesn't adequately cover mental healthcare). But with the severity of his anxiety, it was incredible to see what a change Propranolol made for him, even after just the first dose. I went with him to his GP appointment and the pharmacy afterwards. He took it as soon as we walked out of the pharmacy and 30min later (after we'd gotten lunch at his favourite quiet little place), he actually WANTED to get the bus home, because the difference in how he felt was so dramatic and he wanted to see how he'd feel in a situation that was usually awful for him. Of course, there's no guarantee that Propranolol would work as well for everyone -- pharmacogenetics, his own epigenome, etc. But it's certainly an interesting case, especially since he didn't believe it would do anything for him, haha.
@MmeHyraelle6 жыл бұрын
I know that these molecules are designed to let the patient be receptive to therapeutic help, well for anti depressives one, i knew. But finding this rare pearl is hard. I've tried so many and doc up here in quebec are somehow relunctant to leave mainstream pills. I didnt even knew about beta block before this video :o And yea, many gets the ability to heal themselves. Im stuck in a sort of vicious circle atm :/
@Ninth_Penumbra5 жыл бұрын
This might be helpful to explain the way that Propranalol is improving yourfriend's symptoms: www.ncbi.nlm.nih.gov/pmc/articles/PMC2898127/
@ericarichardson29833 жыл бұрын
I love learning about all the off-label uses of medications. They can be the only options left for some patients. Propranolol and Spironolactone were life-savers for me anxiety and acne wise. Propranolol worked better for my anxiety than any barbiturate ever did. Also LDN- low dose naltrexone is also being used for treating pain in some ms, fibromyalgia, and EDS patients. Thanks for the great video!
@katiemoss75786 жыл бұрын
I love scishow please never stop making videos
@criswillcri5 жыл бұрын
7:01 The fact that they said "choose to undergo hormone therapy" makes me happy, even tho its a small little thing.
@Luna_Christine6 жыл бұрын
Yay, you mentioned Spironolactone! And you also mentioned the reason I take it. It is a wonderful medication, I’ve also noticed that I don’t get many breakouts, anywhere on my body.... Though, my skin is super dried out because of it. But, I do not care, I am taking a journey I should have started years ago.
@EloquentTroll5 жыл бұрын
Propanalol also prevents nightmares in some patients (including myself), though that probably is related to its anti-anxiety properties.
@ryjelsum4 жыл бұрын
And the anti-anxiety properties are related to preventing the physiological effects of anxiety, like heightened heart rate. That's probably what makes it most useful for nightmares; your body no longer has an inappropriate physical response. Additionally, this makes it a commonly prescribed drug to people with PTSD for very similar reasons, with great results too.
@outistynnanyt51535 жыл бұрын
I was hoping they would mention Lamictal/Lamotrogen, an anti-seizure meditation that also treats bipolar disorder
@virglibrsaglove3 жыл бұрын
I think it's used for fibromyalgia, too.
@joylox2 жыл бұрын
I was on Amitriptyline before, which is an antidepressant, but it was prescribed for me due to its ability to promote sleep and reduce nerve pain. But sadly it gave me nightmares that kept getting worse, making me always wake up sweaty and scared, which is apparently a rare side effect.
@garbagegremlins47072 жыл бұрын
Lamictal gang
@SciencewithKatie6 жыл бұрын
It's awesome when this happens, like the guy that made the first pacemaker was actually just trying to make something to record heartbeats and messed up, and then BOOM.. pacemaker.
@montialarson6 жыл бұрын
Science and history are so cool. I didn't know about the pacemaker. That's interesting. I believe the inventor of sticky notes who was trying to make super glue, but ended up making a sticky substance that came off easy and put it on a piece of paper and now we have sticky notes.
@colinp22386 жыл бұрын
Justin O'Brien I thought that was Frank Zappa?
@C-Murph6 жыл бұрын
That's some science you have there katie
@SciencewithKatie6 жыл бұрын
KennethMichaels Boom and it’s done! 👩🏻🔬
@kabkab84416 жыл бұрын
Science with Katie : Science is full of examples of serendipity. Being a person of science I'm sure you know that.🔬🔬🔬🔬🔬🔭🐳🌍🌎🌏🌌🌃💫
@athenavanbeveren25145 жыл бұрын
Naltrexone is also being used effectively to treat nerve pain in patients with fibromyalgia.
@spark-matter11 ай бұрын
Interestingly it's been also fairly successful as a myalgic encephalomyelitis treatment at low doses. The current theory for why this works is the low dose naltrexone gently encourages more endorphins to release during the natural endorphin process that occurs during sleep, helping cells heal (a similar effect to the healing effects that can come from a runner's high)
@Bakerygo6 жыл бұрын
spirinolactone is also prescribed as a hair loss treatment for women with androgenic alopecia
@jenaepeterson4 жыл бұрын
I take Wellbutrin for my depression and anxiety. Its also used to help smokers quit and people to lose weight.
@anitaevans5361 Жыл бұрын
It also can show up in urine tests, showing Positive test for MDMA & meth, so take note cos not all Dr's know this & can write up a patient taking illicit drugs.
@cindersinned27524 жыл бұрын
Propanolol can also be used for migraine prevention! That's why I take it, so it's nice that it has a side-effect of helping my anxiety.
@ProKiwiYT4 жыл бұрын
Who'd have thought that Arthur just needed cough syrup to stop him becoming the Joker...
@stinkykyle966 жыл бұрын
I've been taking propranolol for anxiety for the past year and it's honestly life changing for me!
@mommywithnokidsss5 жыл бұрын
stinkykyle96 Same!! It doesn't 'cure' the mental symptoms of anxiety, bur BOY will it drag you out of a panic attack!! I told my doctor I was worried my heart was aging and starting to beat in a tachycardic rhythm! Besides mental illnesses, physically I'm healthy, so yeah I was freaking out. But it's changing my life! Proprananol ftw 💖
@thetalantonx4 жыл бұрын
As an abortive or as a maintenance medication? It would be great if there were other options than benzodiazepines that had that much of an impact, able to stop a panic or anxiety attack.
@lucegibbs60444 жыл бұрын
Same! Though I take it as needed on bad days
@angelicablue4 жыл бұрын
I've just started this for anxiety, and I love it! Didn't want that Ativan monkey on my back.
@ArizonaJewell3 жыл бұрын
I take it as well! For me it's a great medication for less severe anxiety, it's nice to have another option other than benzos (which for me is the nuclear option for super severe panic attacks)
@10LettersIsTooLong6 жыл бұрын
I've been on several different drugs to manage my anxiety--quite a few of them were anti-seizure medications or antihistamines.
@Ainiewainy6 жыл бұрын
Wright Family I take an anti psychotica for my depression and anxiety. Works better than most pills I have had before!
@slumpkiid35705 жыл бұрын
@@Ainiewainy bruh, those shits act like tranquilizers, that's why 😂
@thetalantonx4 жыл бұрын
Brains are weird things. I'm guessing one of them was atarax. How did it work for you, assuming I'm correct and you care to share?
@RepubsWannaMarryKids4 жыл бұрын
@@thetalantonx Hey, that guy didn't reply, but I shall. I took, hydroxyzine (Atarax/Vistaril) and it literally did nothing for me. I was at 50mg, but... meh. At 100mg I got kinnnda sleepy? That was all. Antihistamines will often cause drowsiness (think of diphenhydramine/benadryl), which is why a lotta people reach for zzzquil now, or even get hydroxyzine prescribed for sleep. I also took Valium (diazepam) for anxiety/seizures. It helped my anxiety a little. But NSM. Finally I got some Ativan (lorazepam) which is a lower dose than a lot of other anti-anxiety meds, and this one helps me. I take 0.5-1mg, depending on need. Doctors really prefer to stay away from what are termed "controlled" medications which include things like Ativan, Klonipin, Valium, Xanax. From working in the pharmacy I'd say that I saw Klonipin given to a lot of patients that were honestly a bit more in "need" and even edging to to treating other behavioral issues even. But by far Valium was what seemed to be most popular though, so popular it was one of most prescribed medications while I was working in the pharmacy a few years ago.
@bigboredthing3 жыл бұрын
Anti seizure medications, especially Carbamazepine (Tegretol), are great for a variety of conditions, including bipolar, anxiety and migraine. Topiramate is great for migraine but has HORRIBLE side effects.
@thecraftycyborg90245 жыл бұрын
Naltrexone can also be custom formulated into a low dose form and used to treat a wide range of issues. It seems to work on some kinds of pain, which is awesome as it’s far less harsh on the body than stronger drugs like gabapentin and opiates. It’s also being used with some great success in patients with issues like CFS/ME and Fibro. I know several people on it for post-Lyme Disease Syndrome, ME, fibro and/or arthritis who swear by it.
@jakebouchard40325 жыл бұрын
Great vid! Kudos for mentioning Spiro in the context of trans individuals!
@Ceridewn2 жыл бұрын
I've been on 3 medications with multiple uses, all for the same condition, Chronic Hives. Zyrtec which is mostly used for seasonal allergies, Pepcid normally for heart burn and acid reflux and the like, along with Singular which is normally used for asthma.
@AutisticThinker5 жыл бұрын
Anxiety is more complex than you or most doctors have any idea... I have been diagnosed it, and it not the first related problem I was diagnosed with... Anxiety causes countless other problems that doctors tried to treated first (depression when young, and high blood pressure recently). The problem is the anxiety, not it's secondary effects. Beta blockers help a ton! Feel free to turn #3 in to an entire episode! :)
@billstewart16534 жыл бұрын
Even at 63, I’m fortunate not to have to take any prescription drugs. However, a few years back while training for a half-marathon during Cedar Fever time, I noticed that my muscle pains were immensely less than usual. Looking at my processes, the only major change to my regimen was that I was taking Mucinex to reduce congestion and help keep the phlegm flowing. I can only think that the Guaifenesin in this product helped to wash the lactic acid out of my muscles. Purely anecdotal, but works for me - try it for yourself.
@Ryan-wk3mc6 жыл бұрын
3:35 "that's when it becomes a [dependence*]." addiction is a pattern of behavior, while dependence is more concerned with neurochemistry.
@mandyrobbins10414 жыл бұрын
One other surprising medication: Metformin. It may have been developed for Diabetes...but one of the side effects of hair loss actually makes it useful for treating Poly-cystic Ovarian Syndrome. I take it for that very purpose. I have that latter condition...and developed a neck-beard due to it, though I am biologically female, and wish to stay that way. So I take it to help with my own abnormal hair growth, and it works!
@sarajones73725 жыл бұрын
To prevent most of my migraines I take trazodone, which was originally developed as an antidepressant.
@CollegeChick8184 жыл бұрын
I'm on Topamax for my migraines, and that was originally developed for seizures. Still helps in higher doses I think, but for me, it helps my migraines
@maddiekaplan83234 жыл бұрын
Trazedone is something I take for my insomnia (and depression), I take it before bed, maybe it helps you because once it kicks in it makes you so tired
@cellogirl11rw555 жыл бұрын
In addition to what was mentioned in the video, propranolol is also a highly effective treatment for many people like myself who have migraines or Essential Tremor.
@GECKman885 жыл бұрын
I'm glad DXM is starting to get the recognition it deserves, and there are MANY more uses for it.
@dommazzetti71695 жыл бұрын
You know what’s up ;)
@yungsleepy86074 жыл бұрын
LMAOOO
@samuelsmith78665 жыл бұрын
I’m on prazosin, otherwise known as minipress. It’s a medication for high blood pressure, but I don’t have high blood pressure. It helps with my PTSD nightmares 🤷🏻♂️
@secksygrandpa6 жыл бұрын
You'd be surprised how many medications had the same thing happen. The anxiety meds I take, gabapentin, we're created as an anticonvulsant and to help treat nerve pain caused by things like shingles. My mom used to take a similar med, topiramate, for anxiety that has basically the same story as gabapentin.
@psychsoma6 жыл бұрын
Joe LaRiccia Also topamirate treats migraines!
@RobertSzasz6 жыл бұрын
Good ol Dopeamax... It has an incredibly nasty side effect profile.
@secksygrandpa6 жыл бұрын
Roberta D. I forgot about that, my aunt is prescribed topamax for migraines actually
@secksygrandpa6 жыл бұрын
Robert Szasz oh ya, that's why she stopped taking it
@skifflebunch12 жыл бұрын
Topirimate can also help with reducing food cravings and help with weight loss
@bellasagood58806 жыл бұрын
What about zolpidem tartrate?! It's usually a sleep medication but can stimulate damaged nerve endings and essentially "wake up" a person suffering from neurological damage and comas, temporarily making them able to communicate again.
@Brett_S_420 Жыл бұрын
Not just temporarily. They continue taking it to keep the restored brain function. Ending the comatose state is usually a one-way street.
@sifridbassoon5 жыл бұрын
I am in awe that you were able to make it through that video without flubbing a drug name once! I take Quietapine along with a generic Lunesta to help in sleeping. The Quietapine helps "shut down" my brain to prevent "racing thoughts" (as they say in the sleep meds ads). When I researched it, it turns out that it was originally used (and may still be) with schizophrenia. I suppose that makes sense, but I still feel a little weird when I take it every night.
@emilysmith2965 Жыл бұрын
Yes, quetiapine is most commonly prescribed as a mood stabilizer for bipolar, schizophrenia or schizoaffective disorder.
@necromorphous6 жыл бұрын
when I was little I took oxybutinin to calm my overactive bladder. now I'm an adult i take it to control my hyperhidrosis. It actually works better to control sweating than it did help my bladder spasms
@LadyFirelyght6 жыл бұрын
I'm currently taking an antidepressant (nortriptyline) to manage my IBS symptoms. It shocked the hell out of me that it worked but I went from having flare-ups 2-3 days a week to 2-3x in 4 months.
@RobertSzasz6 жыл бұрын
I think you may have confused addiction with dependency in the first portion of the naltrexone segment. Addiction is the (mostly) psychological component. It's possible be dependent on a substance without addiction and you can be addicted to things with no physiological dependency, even though they tend to happen together as they reinforce each other.
@themightychondria6 жыл бұрын
Back when i was doing my internship in the ER, a patient was admitted for hypoglycemia and upon doing the medication reconciliation we came to know that he's on insulin but there was no history of diabetes. Apparently he was abusing HumilinR for bodybuilding.. On the other hands some non-diabetic people even abuse exenatide, metformin and acarbose for weight reduction..
@limiv52726 жыл бұрын
Do people also abuse Levothyroxine for weight loss?
@themightychondria6 жыл бұрын
yeah but its the worst! it increases the risk of Heart attacks and irregular heart beats.. Its even fatal to use in patients with heart diseases. Unfortunately its even a constituent in some weight loss formulations sold..
@mayathomas89344 жыл бұрын
Spiro is awesome, took it for about a year for transitioning! Then it gave me too high potassium levels and tried to murder me so like we’re even
@jimon89984 жыл бұрын
So the joker just needed to have some dextromethorphan to stop his laughter.
@nikjoh062 жыл бұрын
I love this channel. So many fascinating videos that I haven't watched.
@sueshe29056 жыл бұрын
He got a different haircut. Cute.
@newnewsbrooklyn15134 жыл бұрын
Excellent video! Explains the chemical reactions in these drugs in an easy to understand way. I am a nurse and really appreciated this
@berglettemom60456 жыл бұрын
Michael Aranda always does such a great job. Remember when he helped Hank Green with the song “DFTBA?” Those were the good old days...
@franloiacono93066 жыл бұрын
BergletteMom whoa nerdfighteria deep cut ❤️
@jacquejac18405 жыл бұрын
Occasionally, I will feel sudden fear or giddiness with no real reason for the feeling after a seizure with my epilepsy. The doc gave me cough medicine once in the hospital, & the feeling passed right away. I never knew why until this video.
@amberhoward78074 жыл бұрын
I'be been taking Propranolol since I was a young teen for my migraines at a low dose. After having 2 kids and turning 30 I was put on a higher dose for anxiety. I had no clue it was for anxiety. I don;t have to be put on Xanax and I am helping my migraines at the same time!
@joylox2 жыл бұрын
I took antidepressants for nerve pain, and stimulant ADHD medications for dizziness. It's interesting how things can work. But unfortunately I haven't had much luck with those lasting long term, but GABA, which I used to take for sleep issues, seems to work with preventing meltodowns, so I may try that as an ADHD medication.
@gustavgous44526 жыл бұрын
Interesting video. But you guys forgot that (almost) every treatment for Bipolar Mood Disorder was originally developed as a treatment for epilepsy.
@jhe94885 жыл бұрын
Propranolol also is useful for treatment of essential tremor, as well as for migraine prophylaxis
@Domo123675 жыл бұрын
I take it for my essential tremor! Works a treat
@hula625 жыл бұрын
Me too.
@julia393n4 жыл бұрын
Spironolactone was prescribed to me to help with PCOS symptoms. The fact it helps keep blood pressure down is also good for my migraines.
@shingshongshamalama6 жыл бұрын
"What's this medication called?" "Propanolol." "What's so funny?" "Nothing it's just propanolol."
@misterk93184 жыл бұрын
Host has smooth voice and good flow, makes listening and understanding much better.
@randomdude1896 жыл бұрын
Videos like this make me realize how few people actually get treatment they need and MOST ABUSE THEIR ACCESS
@tomf31505 жыл бұрын
Propranolol is also used to treat hemangiomes in babies.
@ante0meridiem5 жыл бұрын
Propranolol can also help with Essential Tremor (especially if it's aggravated by anxiety...) I have tremors in my right hand and my jaw, and have propranolol to take if it gets bad on a particular day.
@musclehank60676 жыл бұрын
my muscles have some surprising secondary uses
@sebastianelytron84506 жыл бұрын
surprising, eh? ( ͡° ͜ʖ ͡°)
@apple543456 жыл бұрын
such as.....?
@zachwax226 жыл бұрын
Who does these?
@liamzakhaev6 жыл бұрын
you know making this profile is very insulting to the actual hank right?
@philrabe9106 жыл бұрын
Which is weird cause he's left handed... lol
@Philemaphobia6 жыл бұрын
Tamsulosinhydrochloride is a prostate medication that is only prescribed to male patients although it works on smooth muscle tissue regardless of gender and can help women with urethra inflammation and in some cases symptoms tied to endometriosis. Metamizol is a non opioid pain medication that can also help to prevent migraines and also helps with period cramps, however it is banned in most countries, while widely used as muscle relaxant in the german speaking part of the world, while it can have some serious side effects it does not damage your liver, stomach and kidneys as much as other non opioid analgesics. Paracetamol not only works like NSAIR without being one, it actually docks to one of our cannabinoid receptors thus it is really a prodrug having similar effects as Cannabinoids.
@anessenator6 жыл бұрын
I was on Spiro (self-med) before I finally got officially prescribed Decapeptyl. It wasn't *as* effective, but it did work!
@timandmoby106 жыл бұрын
6:56 ayyyyy I'm on spironolactone along with estrogen for HRT. I'm glad y'all mentioned that additional use of spironolactone! Also spiro makes me crave salt (since it lets more get peed out, as you mentioned) and it makes me pree a bunch. So that's fun.
@kittycatcaoimhe5 жыл бұрын
My doctor told me to put salt on everything now
@HalTheAl6 жыл бұрын
Can vouch for propranolol - during my therapy for my PTSD I noticed over time that while my brain *wasn't* spinning 500 miles an hour, my body still was. And having IBS pains, sweating and the shakes can really interfere with whatever mental coping mechanisms you've been taught. I still take it now but for a different reason - I can use it to lower my heart rate and blood pressure without it interfering with my ADHD medication. Seriously if any of you suffer from anxiety and are nervous about taking something that interferes with the CNS - talk to your doctor about low-dose propranolol.
@firewalk274 жыл бұрын
The trans inclusive language in this video made my heart happy.
@feralcatgirl4 жыл бұрын
it's not perfect (i took spiro and i'm nonbinary, not a trans woman) but yeah
@jacosc174 жыл бұрын
This channel is generally very good about that, it’s nice
@xenianth.4 жыл бұрын
Except it's "trans women" and not "transwomen" it's a big difference
@nicksalvatore57174 жыл бұрын
@@xenianth. wot
@orchdork7754 жыл бұрын
@@xenianth. what's the difference?
@Gpcas96 жыл бұрын
Thalidomid (Contergan)! Original a sedative with those horrible side effects during pregnancy. But it is still a very effective medicine against leprosy and certain kinds of cancer!
@aajjeee6 жыл бұрын
Gpcas9 only one of the chiral molecules is dangerous
@TheBackyardChemist6 жыл бұрын
there are enzymes in the body that can and do racemize an enantiopure dose, so in practice they have very similar effects
@SciShow6 жыл бұрын
We did an episode about that! Chirality is fascinating. kzfaq.info/get/bejne/o9iEe8lzqMrZgnU.html
@Philemaphobia6 жыл бұрын
The horrible side effects stemmed from a mistake in testing, back in time the animals that where used for testing showed NO negative side effects. Only with using different animals ( a New Zealand bunny) showed similar effects. Secondly there is R-Thaliomide and S-Thaliomide, only the latter prevents regular embryonic development. Alcohol and Meth in the same states of pregnancy for example are much worse, as they influence brain development rather than the physical development which is the effect of thalidomide (contergan)
@josecarlos92896 жыл бұрын
Both are dangerous. It is true that S-thalidomide causes the teratogenic effects and R-thalidomide the sedative effect, but even if you take the pure R-enantiomer there is a biotransformation process in your body that turns it into the S-enantiomer.
@mechnaprime36376 жыл бұрын
When I was younger I was on a medication to reduce swelling and pain in my joints, said medication was originally invented to treat seizures.
@LifeLostSoul5 жыл бұрын
I'm really sad Topamax wasn't mentioned considering it has about 10 different uses that range from anti-seizure, mood stabilizer, treatment for nerve pain, migraine prevention, treatment for PTSD flashbacks, and I feel like I'm reading about a new use for it everyday.
@richardjones42596 жыл бұрын
I take an antidepressant for chronic pain. Also some anti seizure meds are used for pain.
@dee52986 жыл бұрын
Richard Jones Nerve pain, especially fibro pain.
@elizabethfoster42976 жыл бұрын
Both Cymbalta and Effexor work really well for neuropathic pain. I'm on Cymbalta for that.
@maryavatar6 жыл бұрын
Amitriptyline? I started taking that from trapped nerve pain - two weeks later, no more pain. Magic stuff.
@kittycatcaoimhe5 жыл бұрын
Yup! Duloxetine helps for my depression and for fibromyalgia. Still nothing for EDS though
@pharmdiddy51205 жыл бұрын
I've seen sildenafil for revascularization of severely injured skin tissue. Cool stuff! Great list y'allllll
@carolinehoak6 жыл бұрын
*holds medicine while talking to friends* "Have you met memantine?
@just_kos994 жыл бұрын
I was originally prescribed propranolol for the physiological symptoms of anxiety as you described. After I started that regimen, I came down with essential tremor (not related to the med). I went to a neuro doc and he said, "To tell you the truth, I would've prescribed the propranolol for you anyway." My tremor is based on both heredity and some meds that I take. When I DON'T have my propranolol, my tremor is definitely worse, so I know it's helping. I'm surprised you didn't mention gabapentin. It was originally developed for seizures, but they discovered it's very useful for a lot of other things. I originally got it to help me get back to sleep at night. It doesn't make me drowsy, yet when I get up in the middle of the night to use the bathroom, it lets me fall back asleep immediately. In the past, I either couldn't get back to sleep at all and would stay up, or else just lie there for hours. My sister got it to help with pain. I believe there are even more uses, but I'm not sure.
@leegalen8383 Жыл бұрын
I'm on Cymbalta for chronic nerve pain caused by several damaged discs in my neck. It keeps my pain level down to 1 or 2 as opposed to my previous level of 4 to 7. Don't know how it works but has made a huge difference in my quality of life!
@jcherson3 жыл бұрын
Fun fact I sort of expected would come up: one of my mom’s treatments for her inflammatory auto immune disease is Naltrexone
@Ninth_Penumbra5 жыл бұрын
There's a potent anti-epileptic called *Pregabalin* (brand name *Lyrica* ), which is basically a modified version of the neurotransmitter *GABA* ( *Gamma-Aminobutyric Acid* ), which acts as a neural suppressant. It's secondary use is for the treatment of severe *Neuropathic Pain* , such as *Trigeminal Neuralgia* , *Restless Legs Syndrome* & *Fibromyalgia* . There's also anecdotal evidence that it is effective for *Generalized Anxiety Disorder* .
@courtneyskyla5 жыл бұрын
I totally agree with lyrics helping with all those things but I use gabapentin which is in the same family as lyrica and it completely stopped my extreme restless leg syndrome....fixed my insomnia too.
@Ninth_Penumbra5 жыл бұрын
@@courtneyskyla *Lyrica* is the brand name for *Pregabalin* , so it's exactly the same thing. I've personally found that *Magnesium Supplements* are very effective at suppressing the *Restless Legs / Formication* neurological dysfunction symptoms of *Fibromyalgia* .
@georgecolley99706 жыл бұрын
Well done presentation.
@Mekratrig5 жыл бұрын
Djust recently started taking propanolol, not for brood pressure, but to prevent tremors in hands - has been verr effective, big improvement.
@Zahri8Alang6 жыл бұрын
I've done a bit of homework about Propanolol, it was used quite a bit. Some performers like singers took them to ease jitters and general stage fright(aka anxiety)
@purplealice2 жыл бұрын
There's always benadryl, a powerful antihistamine, which also has equally powerful sedative effects. I can't take it for allergies because I can't stay awake enough to read, work, think, drive, or cook. But I've been given it for the "induction" stage of anesthesia. Of course, a number of antihistamines were invented as antipsychotics.
@doragami6 жыл бұрын
This is what happened with prazosin, which is an alpha blocker. Originally developed for high blood pressure, it was found to help ease PTSD related nightmares in veterans. I don't have PTSD myself, but I do have a lot of symptoms that overlap, including terrible nightmares. Prazosin has really helped with that. I still have some uncomfortable dreams but they rarely reach the point of triggering too much adrenaline response and waking me up in a panic. It's great!
@dumbcroissant64102 жыл бұрын
I take fluvoxamine, an anti depressant for ocd, but it’s also been used and studied for Covid 19, mainly preventing at risk people (who have Covid) from getting sicker and being hospitalized
@elizabethfoster42976 жыл бұрын
There are a huge amount of medication prescribed for off-label use. Many like some on this list started for one thing and ended up being almost exclusively used for another. Most of mine are off-label use. I take Cymbalta, an anti-depressant, for neuropathic pain and Prazosin, a blood pressure med, for PTSD induced nightmares (which also helped with my migraines).
@montialarson6 жыл бұрын
Image you're in that Viagra study. You're taking a heart med and the doc asks, "do you have any side effects?', you're like, "uh yeah um well It doesn't seem to help my heart, but I keep getting these intense erections." So the people who made it are like "okay so it's not helping any ones heart, but it's giving everyone erections, let's just say it's for erectile dysfunction."
@IceMetalPunk6 жыл бұрын
I mean, it *does* help their heart, too. The erection thing is a secondary effect.
@Philemaphobia6 жыл бұрын
No, especially Viagra is contraindicated for men with heart conditions.
@Nmethyltransferase6 жыл бұрын
I don't think you understand how men think. In reality, it was more like this... Doctor: "Well, Mr. Smith... It turns out all the tests we did showed that you had no improvement whatsoever in heart function. And it turns out you weren't getting a placebo--it was the real test drug, after all! I know, it sounds disappointing, but that's just how these things go, sometimes. Anyway, we're wrapping up the trial. So, we'll need you to bring the leftover pills back." Mr. Smith: "Err... D-do I have to?" Doctor: "Oh, yeah! The drug is an unapproved chemical. The trial is over. And it's not like it was benefiting you, anyway. Leaving it lying around in your medicine cabinet would violate every rule of medical ethics _aaand_ probably break a half dozen laws. The drug company does _not_ need the FDA tearing it new orifices! So, anyway... Can you make sure you bring the bottle back at your next visit?" Mr. Smith: "No." Doctor: "What!?" Mr. Smith: "What?"
@callabeth2585 жыл бұрын
It is still used for pulmonary hypertension but we use different doses for the two conditions. The reason we want you to check with your doctor or pharmacist before taking sildenafil and other heart drugs is that it can definitely reduce your blood pressure especially if taken with a family of drugs called nitrates that are most commonly used for angina pain, this combination can drop your blood pressure so quickly that you can go into cardiac arrest. That’s why if a man is having a heart attack the paramedics will ask if he has used any drugs like viagra, cause first line treatment is aspirin and nitrates which could kill him quicker if he has sildenafil in his system. - Australian Pharmacist
@stanburton62243 жыл бұрын
Propranolol is also being investigated in conjunction with psychotherapy to slowly eliminate the debilitating panic symptoms of PTSD by taking advantage of how memory is a destructive process and requires the brain to regenerate the memory after each recollection. And how the emotional/physiological effects are remembered separately from the factual memory. In this way the Emotional response is reduced after each recollection episode.
@Lioness0064 жыл бұрын
I'm gonna need more of these. It's so interesting! I would definitely try the hormonal acne one.
@williamrobinson60592 жыл бұрын
In the classical music world, we use Propanolol in small amounts (one dose of 20-60mg) as a tool to mitigate the physiological symptoms of audition and performance anxiety. I’m not sure how common this is - it’s a /bit/ of a taboo. However it seems to work for many who try it. It certainly works for me.
@blee519985 жыл бұрын
I now know why one of the docs at my health center added propranolol to my pascripton for my depression and anxiety
@fisqual6 жыл бұрын
No Diphenhydramine?
@carolvedder35552 жыл бұрын
I started using aspirin for horrible toothaches. It worked much better than the moonshine my mom gave me . This was when I was 12yo and in middle school. I didn't know anyone else who carried a bottle of aspirin in their purse. This was a life changing event for me. I couldn't believe there were kids who never had a toothache. I eventually started getting dental care. I went to nursing school in the 70's and learned the chemistry and uses for ASA. I used it for menstrual pain before antiprostaglandins became available. If you don't have Ibuprofin aspirin takes care of pain with cramps and with headaches ( really ). Before I get hated for suggesting aspirin, stomach ails can be avoided by eating something first and using only needed. It should not be used ever for those who use with anticoagulants such as heparin. One more thing : low dose aspirin eg. 82 mg will help as temporary, temporary measure to help those with heart attack or stroke symptoms before they get to hospital. I keep this in my purse and car.
@Eloise_Please3 жыл бұрын
I am on Amitriptiline to control a neurological movement disorder, but we discovered these effects by using for pain medication! It doesn't help much with the pain for me, but has reduced the frequency and severity of convulsive episodes significantly and even sped up my recovery time.
@caroljomartin30515 жыл бұрын
I was prescribed propanalol for headaches. It helped some, but after about 3 weeks, my ptsd was completely GONE! Later, I read in a science magazine that propanalol was being tested on veterans with ptsd. I know first-hand: it works!
@EStarstruck6 жыл бұрын
I took naltrexone for dermatillomania and it sadly didn't work but I've heard it does a lot of good for many people with skin picking/hair pulling. Another medication, Lamictal, is used for seizures at high doses but at 300 and lower its used for manic depression and it's helped my anger issues greatly. Side uses to meds ended up really helping me.
@WildFyreful6 жыл бұрын
Ha! I actually use propranolol for performance anxiety. Thanks for giving it a mention. :D
@ZaCh-wk3oc6 жыл бұрын
Sweetpea from riverdale sure knocked this one out of the park. I didn't know he was such a smart fella
@myshreksbox2 жыл бұрын
I don't think I was on any of these medications but I was on a mood stabilizer that acted like an antidepressant as well but it was used primarily for a mood stabilizer
@hyperactivehyperbole2 жыл бұрын
Neat fact, nuedexta , the dextromethorphan/ quinidine combination is also being tried as adjunct therapy with prescription ketamine infusions under medical supervision in the treatment of treatment resistant depression to help the beneficial effects of ketamine last longer. Didn’t notice a difference for myself but wanted to mention it for anyone that it may be of help.
@kriegswaffel2 жыл бұрын
I didn’t know it’s being studied, but using a beta blocker to treat anxiety in stressful situations like exams was low key common knowledge at my university. We’d all just assumed it was due to lowering the heartrate and blood pressure, kind of like medication-based bio feedback.
@stevenduvall25494 жыл бұрын
At 5 mg, finasteride is a drug that helps with an enlarged prostate, but at 1 mg it helps prevent, and even reverse, male pattern balding.
@RequestedTutotials6 жыл бұрын
I got excited when you mentioned naltrexone, because I and many others use it in very low doses (LDN) for fibromyalgia.
@seannot-telling98066 жыл бұрын
This one was interesting and only seemed half as long as it really was. But you forgot the latest off label mix. Finasteride and Minoxidil for MPB. Even finasteride by it's self has an effect. Please do more on OFF LABEL drug use.
@MmeHyraelle6 жыл бұрын
Finasteride and dudasteride are designed to block dihydrotestosterone for causing hair loss. The later one, dudastéride is 10x effective and better for the body, take this one if you have an overload of DHT.
@celinak50626 жыл бұрын
+
@n0m3Dr38yC2 жыл бұрын
Naltrexone is also used as a weight management medication when combined with bupropion AKA Wellbutrin, a common antidepressant. Both are used for the same reasons as for non-drug addictions and overeating can be treated as an addiction. Bupropion is also commonly used as a smoking cessation medication due to these same effects. The combination medication of naltrexone/bupropion, Contrave, is generally considered to have fewer negative side effects than more traditional weight management medications. It's certainly not a weight cure by any means, but since diet is 90% of weight loss, reducing food cravings in those actively trying to lose weight can increase the effect and improve weight loss outcomes.
@SP-bb7hu6 жыл бұрын
The clover can solve problems with brittle bones better than any calcium supplement (Aarhus university, 2015) - original study was on clovers effects on menopause, but it had little measurable results. However a sideeffect found in all patients bone density had increased...
@oliviawatts26052 жыл бұрын
I was hoping yall would mention propranolol since you were talking about blood pressure meds. It was very helpful for me while I was waiting to get a daily anxiety med prescription.