So how do you determine if a drug is basic or acidic based on pKa?

one of the best explanation

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You explain everything so clear. Thank you!

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Very useful. Thank you!!! :)

so helpfull thanks a lot :)

it just means that the solution has a concentration of hydrogen ions (H+) of 0.0000001 moles of hydrogen ions in one liter of water. That's in the middle of the pH scale, so we call it "neutral", meaning it's BOTH an acid AND a base...amphoteric is the term.

Thanks alot.

awesome video! Favor for baby chemistry students like me: can you connect this to the salt form of the drug prior to it dissociating to an acid? I am just confused because the acidic form at this point will be an anion so is ionized, how will this pass through the lipid membrane? can you also add why the salt form of the drug is important for its solubility and absorbability?

More back round about acids and bases !

Oh thank you for replaying ! One question if you have time :D ! this has a lil to do with acids and bases which I don't get .... I know what acids and bases are. Acid are that Produce hydrogen ions (H+) when mixed with water and bases Produce hydroxide ions (OH-). My question is what acids and bases really do! are one dangerous than the other ? or cause a stronger reaction like if you put acids or bases to your hair it will change color! that's what I don't really get !

Very useful

very helpful

i'm postgraduate student & i wanna to study pharmacology so i need some help if u can about the subjects that related to postgraduate pharmacology M.D & PhD....

I know having a ph of 7 means its neutral meaning it has no effect whats so ever ! am correct ? or wrong ?

This podcast assumes that the viewer has taken basic chemistry and knows what acids and bases are. This podcast ONLY talks about acid/base chemistry in drug design. There are plenty of other resources on introductory acid-base chemistry!

He was talking too much and going too fast people can hold no more than 7-9 things in their memory at once.

Bakwas