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In this video, cardiologist Dr. Bret Scher dives into a recent study that suggests an increased risk of heart attacks from a low-carb diet. A Twitter profile even declared, "Finally, good science!" But does this study really provide conclusive evidence that ketogenic diets cause heart attacks? Spoiler alert: No! Join Dr. Scher as he dissects the flaws and limitations of this study and discusses why it doesn't contribute meaningfully to our understanding of low-carb diets and heart health.
Most notably, to fully benefit from a ketogenic diet, it's essential to restrict carbs enough to transition to a fat-based metabolism. Diets that are low-carb compared to the Standard American Diet (SAD) but not low enough to induce ketosis won't provide the unique benefits of a ketogenic diet, making the health outcomes incomparable.
Key Points:
- The study in question used an observational nutrition epidemiology approach, often considered to provide low-quality evidence.
- Low-carb was defined as less than 100 grams of carbs per day, which is not truly low-carb and definitely not ketogenic.
- The majority of participants provided only one 24-hour food diary over a decade, a poor representation of long-term eating habits.
- The study participants who ate low-carb were generally less healthy to begin with, skewing results due to the healthy user bias.
- There was no clinically significant increase in LDL cholesterol between the groups.
- The hazard ratio for cardiac events was 1.3, which is marginal compared to stronger associations like smoking and cancer.
Studies Discussed:
Association of a Low-Carbohydrate High-Fat Diet With Plasma Lipid Levels and Cardiovascular Risk
www.jacc.org/doi/10.1016/j.ja...
Lower carbohydrate diets and all-cause and cause-specific mortality: a population-based cohort study and pooling of prospective studies
pubmed.ncbi.nlm.nih.gov/31004...
Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis
pubmed.ncbi.nlm.nih.gov/30122...
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Timestamps
0:00 Introduction
1:09 Study background
2:04 Problem #1: How the study defines low-carb
3:25 Problem #2: Missing details on the types of carbs people ate
3:57 Problem #3: The data collection
4:39 Problem #4: The (un)healthy user bias
5:15 Problem #5: Clinical significance
5:53 Problem #6: The magnitude of the results
6:16 How to use this study as a physician
7:11 The importance of quality data
8:16 Conclusion
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