Love this series. Keep up the great work Layne!

Having completed a MS in Nutrition, I can say no one can sum up an entire sequence of graduate courses like Layne, especially not in just a few short KZfaq clips. People do not realize the value of the educational material translated through this video series. Thanks for the series, Layne. It has been a nice refresher in macronutrient metabolism and biochemical pathways!

THIS IS GOLD! It's ridiculous how you just gave this high quality content out for free😂 keep them coming Dr Norton

I like that you recently took your channel to the more authentic side of you. Thanks for the clear videos you providing. Keep it up and just be you, its grate.

These are clearly going to become the go-to source for a clear, science based explanation of this subject. Great work!

Nice work, Layne.

Really great series Layne, as an improvement suggestion, have a look at Dr Rhonda Patrick's videos where she puts subtitles to explain the jargon while she carries on with the message - I feel it works really well

Thank you! “I’ll say it again...” always helps me understand. But I had to go back to watch again to absorb the move from the high fat/low carb surplus comment on no insulin needed to the low fat/high carb deficit where insulin is referenced on the fat storage. But second time around, I caught the emphasis on PERCENTAGE of fat stored. Got it. Thanks again for putting these out!

Didn’t understand a word. But I think I still loved it.

Thanks so much for doing these Layne! Regarding suggestions, an episode on fat metabolism in HIIT vs steady state cardio would be great!

Loved this!! Superb one Layne!

Finally, education that can be applied. I love the lecture format and the detail. So helpful. Thank you.

Your videos are like science seminars, so much knowledge. Thanks for posting this. Keep them coming :)

Really loving these series! Many hails and thanks for breaking it down to a form that's easily to register :)

Love this series, never understood how I could lose weight on such high carbs since we've always heard low fat, low carb and high carb is evil. Working with a coach now and I'm on a good amount of carbs and losing...thanks so much for these informational, proven, scientific videos.

Awesome video again Layne. Loving this series. Keep them coming!

Layne, I really appreciate all the great content you put out, people are going to realize this if your content ever stopped for some reason. Also, the more I watch your videos and the more I learn, the less I feel like I know. Anyway, here's something I'd like addressed. If calories are equated (when in a slight caloric surplus ; say 50-200kcal over maintenance) if you get a higher % of your calories from protein, will that help limit fat gain since protein is harder to turn into fat? Or will it not matter and you will just store the fat you do ingest? Using myself as an example; would these macro breakdowns make a difference (Calories 2755, P198, C318, F76 OR Calories 2755, P250, C266, F76). I look forward to your answer and keep the great content coming. Much love

this is an amazingly helpful and well explained video.

Bro these videos are awesome. Haven't been here in awhile but heard the Rhino suggest you on Mike o Hearn's channel, so I had to come back! Subbed!

This series is pure gold!! I am having a biochemistry exam in 2 days so I guess this is studying for me! :)

Oh wow the amount of infos here just bring it to the next level!!!the more I learn the more I need to learn! AMAZING series!!Keep it up!👊

When you have a scientific brain and you're trying to explain this to someone that doesn't have a scientific brain and they look at you like this 🙃🙃🙃literally standing on their heads....😩

This was worth my lunch break

Layne, I’m not sure you respond much here. I have been on keto for about a year, lost 57 pounds. I admit that the experts on keto did have me believing that insulin was very bad. Still, keto kept me on the straight and narrow and did help me focus on healthy eating and oils that are better for you thank canola, etc. I know this is all in debate on what is good and what isn’t good food. So, two weeks ago I started flexible dieting. I do enjoy the fact that I can eat things I’ve been depriving myself for so long, such as yogurt and fruit, cereal, oatmeal. I am finding it challenging to get my fats from over 150 grams to about 50-60 per day. Complete change. I still don’t understand how many carbs I should eat every day to lose weight. I believe my maintenance calories are 2250, because I am 150 pounds, 5’8 male. So I’m trying to eat in a 300-500 calorie deficit each day, but having been low carb for so long, and not having to worry anymore, I find it hard to understand how many carbs are too much. I do train with weights 5 days a week and do cardio, 40 minutes a day and abs almost daily. I hope the 1700-1800 calories is not too little to lose muscle. Can anyone help? Thanks.

Thank You! Loving these video’s ❤️ Your explanation of how IIFYM works is so clear & easy to follow.

Do the constant high insulin fluctuations caused by high carb diets impact our bodies ability to store fat vs a more reserved carb intake? Anecdotally, ive found my body fat levels drop off rapidly with a more reserved 100g of carb intake per day.

Substantive content is great (as usual), and delivery is a massive improvement over the last video. Good job Layne and thanks very much for the video series!!

These lectures have straight up inspired me to go back and finish grad school.

Love these science videos explained in an easy way to understand.

Amazing video, I really, really enjoyed that. Thank you Layne!

That was awesome Layne. I get a lot out of your videos.

Thanks for making this series. This was very helpful for understanding the importance of negative energy balance to loss body fat irrespective of high fat or high carbs intake.

Amazing content. Looking forward to watching the rest.

This is awesome! Thanks, Layne please keep them coming.

amazing informative video , love your series sir , thank you so much for the time and effort you put in to make this understandable !

Great video Layne, very informative!

Absolutely helpful! Exactly the breakdown I've been looking for!

These vidéos are amazing!!! Thank you for taking the time to make these. I feel a bit overwhelmed at the information because I have zero science background but I am trying to get the gist!!!!

great video as always!

Layne, so, if total energy and protein are being tracked, does the ratio of carbs and fats that I am eating, be it for bulking or cutting, makes a difference in the long run? In other words, is trying to eat a minimum amount of fat, like many "bros" preach, a waste of time, if you are controlling for total energy?

Another great video layne! Love it 🙌🏻

I love this new educational series. Thank you,

That's actually a great revision for physiology class!

I love this, Layne gets right to the point- no bullshit.

Thanks for all this great free info! Really appreciate it

Nice video. I don't agree with some of your tactics on maintaining health through diet, but this series is worth watching just for the scientific understanding 😊

I love how you explained this and made it understandable for people (:

@biolayne The hormonal component....based on what you're saying, why is that once women go through menopause, women who formerly had no problem maintaining their ideal BMI often suddenly find the pounds accumulating, no matter what. I, and many of my other active and fit friends, have lived this. Been fit and worked out my whole life, ate relatively clean and never EVER had a weight issue. After 45, bam....I started gaining. After 50, I had gained 10 lbs (from my stable, pre-menopause weight) that will not move. The complex hormonal system of the female body seems geared to preserve whatever estrogen stores possible, post-menopause. Fat storage is part of this. How do we address this?

Hello from Poland bro. Keep doing good work.

Excellent.. refreshing all of those things from biochemestry

This was such an awesome video, thank you! Very informative. So i have a few questions, would it be better for weights training to access glycogen on a higher carb low fat diet because of the higher insulin? And then how much does your own genetic makeup and hormone levels come into to play when storing fat? Is it just common sense? For eg, higher cortisol would mean more fat would be stored regardless of intake? Or is what you presented the general rule of thumb with fat storage, high insulin means more % of fat stored, thanks again bro

Please provide a meal plan for metabolic damage .

Your videos have been excellent recently! Bravo!

You should make a video about how pre-workout works, and what all those weird ingredients do

Why on Earth don't you have more subscribers? This is very valuable information for us fat people to understand and use. Thanks Dr. Norton.

Awesome videos Layne, keep them up. When someone is prepping for a show how do you usually break down their macros %wise and also do you simply add more cardio once they hit a very low caloric input. Thank you.

How does the body respond to healthy fats from veggies and nuts compared to unhealthy fats in animal products?

Love your mind I’ve learned so much from you!! Can you focus in on high carbs and how high or when does weight gain begin with a high carb diet🙌🏼

Great series

Awesome! Thanks for these. Very good info on the internet.

As always... you are rocking it. Thank you. So basically to loose body fat is calories in versus calories out.

Outstanding video, good sir 👏

Carbohydrates turning into fat is a pretty small amount. I tried a low fat diet and even in a calory surplus I didn't put weight on I just began to sweat and have more energy. I reduce calories and I slowly lost weight. I actually found low carb to be better because you end up less hungry as your insulin levels drop.

Love this. Perhaps a summary at the end?

Absolutely brilliant stuff

Thank you Layne

If you eat 200g of fat and burn 170g, the 30g left, stored as fat, will ADD to the fat you already have! How is that losing fat? Isn’t the only way to lose fat is to burn/oxidize more fat than you eat?

i dont know hwo many times i have seen this .. pure gold !!! t. Thank you

What is the first fat is going to leave the body ? visceral fat? Or subcutaneous fat?

Layne you will hit over 2-3 million subscribers over time ....good vids

Smart Layne is smart....

Layne, in the context of someone doing Intermittent fasting, typically the first meal of the day causes a high insulin peak. If our goal is to remain lean, would you advise that meal to have both moderate carbs and fats (knowing this might cause more fat to be stored), or high carbs and low fat, keeping the fats fore the following meals whose insulin peaks would be smaller?

Awesome video, great information!

Your fat loss series videos are the BEST!

I'm considered obese, i lost 70 pounds doing a deficit, but a lot times I would come to a plateau or gain while on this deficit, I found few videos explaining insulin and now I stop snacking between meals and stop eating after 6pm till the next morning, still on a deficit and the fat burning engine is on again. slow but it's on. 💪👌 😊

Conclusion: If you eat high carb low fat, you will be storing more of the fat you eat and oxidize less fat, but you also have less fat in your diet to store. If you eat high fat low carb, you have more fat to store, but you also have higher fat oxidation. So... just track your calories, regardless of what you eat, and also eat a larger percentage of protein and fiber for thermic effect and filling qualities?

If you’re say burning 170g fat and storing 30g fat out of the 200g that comes in with that example, doesn’t that mean your overall body fat is increasing by 30g? That’s confusing me with fat intake vs fat oxidation.

So if I was eating in a surplus and ate more fat than carbs, I would be getting fatter faster then if I was eating in higher carbs than fat?

Thank you coach really helpful

Lane, what if we balance fat and carbs while maintaining high protein?

excellent!!!!!

Hi Layne! I understand it’s all about the balance! What I’m curious about is how do your equations change based on types of carbs taken in or type of fat taken in? For instance - a vegetable v a soda? Or healthy fats v trans fats? I know that the more your food is nutritious and packed with nutrients, the better but I would love to understand the science behind why! How would this affect your total energy input if you’re eating healthy foods v non healthy foods but in the same amount of energy in (for example: 200 calories of healthy v 200 calories of unhealthy foods). Thanks! Loving your videos!

Thank you Layne! I’m kinda a nerd 🤓 but not on this topic. You kept super Scientific but easy to understand. Looking forward to cutting after maintaining my 30 week Reverse 🙌🏾👙

So in short. To maximize fat loss. Need a caloric deficit with a low carb diet, right? What about when you plateau at that caloric intake or your body adapts to the physical demand and you stop losing weight?

Does this mean that I will store more fat from a meal with carbohydrates and fat than I do from a meal with the same calories, but just carbohydrates?

i love the series, i hope we can see more of these videos, GREAT CONTENT!!!!! thanks mr norton

How does MCT oil fit into this? I know it's digested slightly differently, but dont know the specifics.

Love the vid 👍🏽 could u pls address metabolic adaption and explain ways to prevent this while dieting.

So you’re saying that carb cycling doesn’t affect how much fat you lose but could affect the rate you lose it?

excellent Fat Loss tutorial...

Can I infer from this video that, fat loss can be achieved via negative energy balance + high carb, low fat? I have loved your series but because I have no knowledge on the technical side of these things I feel less confident in extracting the actionable points.

Can you still burn fat while having low testosterone and thyroid problems?

You are my hero! Great job!

How much of the carbohydrates end up being stored as well in the low fat high carb scenario? A higher percentage of fat is stored yes but after the carbs are converted and stored what ends up being the overall total?

Loving it man

Superb video. Love your t shirt

helpful, thanks...

So in order to get gluconeogenesis going, we need to put fat into adipose tissue as a triglyceride then it becomes fatty acids and it can ONLY then be used for energy? Ppl think we can burn fat like protein and carbs! Thanks for this

How the fat will be stored if I'm in a caloric surplus with HC and 0 fat if DNL is very inneficient process?

@biolayne So typical cutting cycle 2-3 days low carb (lower calories) and then 1 day high carb (higher calories) to theoretically keep metabolism high can be simplified just to higher and lower calories days without counting macros, and effect will be the same when in calories deficit?