Cloning animals - Dolly the sheep - GCSE Biology (9-1)

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Mr Exham Biology

Mr Exham Biology

5 жыл бұрын

This video is for Edexcel IGCSE Biology 9-1 but is relevant for many GCSE Biology courses. It covers these specific objectives from the syllabus
5.19B Describe the stages in the production of cloned mammals involving the introduction of a diploid nucleus from a mature cell into an enucleated egg cell, illustrated by Dolly the sheep.
5.20B Understand how cloned transgenic animals can be used to produce human proteins.
You can download a teaching PowerPoint for this topic here: www.mrexham.com/5-uses-of-bio...
Or one for the whole course here: www.mrexham.com/store/p118/Ul...
I also have a TES Shop here: www.tes.com/teaching-resource...

Пікірлер: 86
@angelitawansa6533
@angelitawansa6533 Жыл бұрын
please i have a simple question, instead of the nucleus from 1 being put in the egg cell of 2 them into the surrogate 3, why didn't they put an egg cell of 1 straight into 3?
@chloes.editing6492
@chloes.editing6492 3 жыл бұрын
Wow thank you so much! I was struggling to understand this concept and I watched your video and I understood it perfectly thank you thank you thank you
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@gigigaga666
@gigigaga666 2 жыл бұрын
Hello Mr. Exham, i was curious if it is possible to crispr gigantism into the dna?
@kalleruuska7163
@kalleruuska7163 3 жыл бұрын
I wanted to know more about the Dolly sheep and this was the simplest and easiest explanation to understand. Thank you!
@MrExhambio
@MrExhambio 3 жыл бұрын
No problem
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@yusrxn
@yusrxn 4 жыл бұрын
THANK YOU THANK YOU THANK YOU !!
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@DaRyteJuan
@DaRyteJuan 3 жыл бұрын
A very dignified video. Thank you.
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@rukukaru2450
@rukukaru2450 3 жыл бұрын
Thank you for all the pictures! I would get lost without it lol
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@TheEarthCreature
@TheEarthCreature Жыл бұрын
Can animals 1 and 3 be the same animal, theoretically? As in, could an animal birth its own clone?
@bennguyen1313
@bennguyen1313 5 жыл бұрын
Has the Yamanaka technique superseded the Dolly method (transferring the nuclear dna of a somatic cell to an unfertilized oocyte cell)? If not, when is one technique more applicable? Since four of Dolly's sisters didn't suffer the same fate... Dolly's early death at 6 years old, is often attributed to a viral-cancer, not related to the cloning procedure. But didn't Dolly also have advanced arthritis and CVD for such a young sheep? For example, some suggest that Dolly retained the epigenetic aging signature of the donor sheep.. her telomeres were much shorter than her chronological age would have predicted. Has the connection between cloning / teleomeres / and life-span been established? On the Life Scientific Podcast, Ian Wilmut mentions that sperm would normally signal to the egg to start dividing, but in this cloning technique, an electric shock to the egg is used! He also says that while all the genetic information came from sheep #1, there are factors in the egg (sheep #2) that change the expression of that DNA! However, I wonder how much influence the *environment* (sheep #3's horomones, stress, etc) also has over the DNA!
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@birdie7344
@birdie7344 Жыл бұрын
thank you so much!
@srworship8821
@srworship8821 4 жыл бұрын
Thank you - This was really helpful!!
@sandhyaedirisinghe2247
@sandhyaedirisinghe2247 3 жыл бұрын
yeahh
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@amanuelyirdawteshome6353
@amanuelyirdawteshome6353 Жыл бұрын
Short but perfect
@nellsummers7921
@nellsummers7921 Жыл бұрын
where's the subtitles
@jayferrier3298
@jayferrier3298 3 жыл бұрын
cheers for the sick content brotato, its pretty lit🥶😈💯
@tiwrun
@tiwrun 2 жыл бұрын
Sheesh
@tobysage2990
@tobysage2990 2 жыл бұрын
🔥🔥
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@FalGamingHD
@FalGamingHD 3 жыл бұрын
Wow thank you so much my g, cold 🥶
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@sandhyaedirisinghe2247
@sandhyaedirisinghe2247 3 жыл бұрын
good thanks Mr.
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@itxscientist6225
@itxscientist6225 3 жыл бұрын
Well explained
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@Hasan-hc5de
@Hasan-hc5de 4 жыл бұрын
Had an exam. Thanks
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@fizzymizzy_
@fizzymizzy_ 8 ай бұрын
that dolly pun was great
@Versatilad
@Versatilad Жыл бұрын
The link is missing! How was the egg fertilise?
@rotarytexas3972
@rotarytexas3972 Жыл бұрын
It doesn't
@rayanna9550
@rayanna9550 2 жыл бұрын
This video precisely answered my questions about Dolly (^_^). BTW, can I know what app (or online website) was used for removing the background of the person speaking?? I really need if for my school project. Thank you!
@khizarhayat8777
@khizarhayat8777 2 жыл бұрын
It is called a green screen
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@calvin..
@calvin.. 2 жыл бұрын
@@khizarhayat8777 LMAOOO
@calvin..
@calvin.. 2 жыл бұрын
just use something like greenscreen on zoom and like record it then use and editing software and add urself to the video.
@learav717
@learav717 3 жыл бұрын
Isn't it the same if you just use the egg cell of sheep number 1? Why was it needed to enucleated the egg cell of sheep number 2 when you could just use the full egg cell of sheep number one (which already has the dna of sheep 1) or enucleate the egg cell of sheep 1 and fuse it with the dna which would be extracted from another cell of sheep 1? Also why is it needed for the new cell, after its fused, to be implanted in a 3rd sheep?
@BANANA-go5oq
@BANANA-go5oq 2 жыл бұрын
The egg cell has a random mix of genes due to meiosis, not the full genome.
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@leangsothyro5301
@leangsothyro5301 Жыл бұрын
why do we need 1 more sheep to put the the embryo in we can just out it in the second once
@gangasenthilgangasenthil7825
@gangasenthilgangasenthil7825 4 жыл бұрын
Your the best and genius
@gangasenthilgangasenthil7825
@gangasenthilgangasenthil7825 4 жыл бұрын
Good
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@sarunkrishnan9435
@sarunkrishnan9435 2 жыл бұрын
Sooo cool
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@jonassalem9675
@jonassalem9675 2 жыл бұрын
why does it have to be an egg from another sheep?
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@johnganiron8486
@johnganiron8486 2 жыл бұрын
Why did the biologist pick a sheep to clone?
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@djamilaaaxo
@djamilaaaxo 3 ай бұрын
1:22 / 4:10
@mandokabazo1826
@mandokabazo1826 5 жыл бұрын
Very good video
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@joshua5838
@joshua5838 4 жыл бұрын
Can we actually bring back extinct animals?
@Wizlingss
@Wizlingss 3 жыл бұрын
Yes unless if you have a reproductive cell sample of a female and male full preserved
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@gazey
@gazey Жыл бұрын
Man…why don’t I have this topic on my gcse biology textbook
@abdulazizmohammed2515
@abdulazizmohammed2515 Жыл бұрын
wrong syllabus then tf are you doing here
@gazey
@gazey Жыл бұрын
@@abdulazizmohammed2515 because i enjoy learning it? do i have to have it for my gcse to learn?
@abdulazizmohammed2515
@abdulazizmohammed2515 Жыл бұрын
@@gazey bro you make no sense i swear you literally said that you cant find this topic in your textbook which means that your following the wrong syllabus and if you take your igcse exams seriously like everyone else you would know not to waste time you never said nice video or this is intreasting literally what you said was why cant i find this topiic on my textbook....
@gazey
@gazey Жыл бұрын
@@abdulazizmohammed2515 it was a rhetorical question…
@gazey
@gazey Жыл бұрын
@@abdulazizmohammed2515 I’m doing coordinated science which doesn’t have this in its syllabus
@themoralshow902
@themoralshow902 2 жыл бұрын
Thank you❤️😊 From Sri Lanka 🇱🇰😍
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@alexcatanescu3075
@alexcatanescu3075 3 жыл бұрын
fanks luv
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@neet_pedia6118
@neet_pedia6118 4 жыл бұрын
Nice video. Love from India. :-)
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@StarLightDawnOpensALight
@StarLightDawnOpensALight 2 жыл бұрын
Aint cloning som like- {there is this ONE THING} ... (and you cloned it){HORRAY!!!!!!!!!!! .... YOU'VE GOT THE SAME [U] BUT A DIFF [U]}
@StarLightDawnOpensALight
@StarLightDawnOpensALight 2 жыл бұрын
shown here .... WE NEED A BODY TO SACRAFICE!!!! is there possible one elsehow? I KNOW FOR PLANTS ALR!! but seriously ........... I really really gotta ask ... for the Human-Bio not Plant-Bio
@quranwilliams7469
@quranwilliams7469 4 жыл бұрын
Who has been sent by class 7a
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@x_r_j_w
@x_r_j_w Жыл бұрын
who got sent here for R.E
@mahirfoisal1992
@mahirfoisal1992 3 жыл бұрын
ahhhh why british
@farhanahmedheathland5923
@farhanahmedheathland5923 2 жыл бұрын
kzfaq.info/get/bejne/Z62cariCza3Yc3U.html
@Randomeeeeeditz001
@Randomeeeeeditz001 2 жыл бұрын
Why not?
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