Diclofenac sodium topical gel (Voltaren gel) and diclofenac sodium topical solution (Pennsaid) can help ease arthritis pain from osteoarthritis. They're applied to the skin of the affected joints, typically 2-4 times daily, depending on which topical product you use. Some common side effects of topical diclofenac include dry skin, redness, and itching.
Because diclofenac is a non-steroidal anti-inflammatory drug (NSAID), these topical products can also raise the risk for NSAID-related side effects, such as blood clots and high blood pressure. While the diclofenac sodium topical solutions are only available by prescription, you can get diclofenac sodium 1% topical gel over-the-counter or by prescription.
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