DNA Structure and Classic experiments, excerpt 1 Instructor: Eric Lander View the complete course: ocw.mit.edu/7-01SCF11 License: Creative Commons BY-NC-SA More information at ocw.mit.edu/terms More courses at ocw.mit.edu
Пікірлер: 136
@horizon2reach5617 жыл бұрын
That is why it is MIT ! professors not just teach , they also inspire and make you feel interested , that is what matters , you can have a thousands books to learn the materials , but where you discover the passion? Thanks MIT for these free materials
@tartanhandbag6 жыл бұрын
i've seen others from MIT courseware, lectures by people who literally have nobel prizes, and they are some of the most boring lectures i've ever seen - I couldn't even get through them. Eric Lander is an amazing lecturer though.
@avi21252 жыл бұрын
Ah the legend Eric Lander and those marvelous MIT sliding boards with thick stubby chalks so the writing is silky smooth! "DNA is just scaffolding" (chuckle)
@navyflibertyjibet9 жыл бұрын
I love the way this guy lectures
@25chrishall8 жыл бұрын
This guy's a hell of a teacher. We need more professors like this. That is, we need more professors who are just as passionate about teaching as they are research.
@gaaraofddarkness4 жыл бұрын
An eminent teacher is someone who has a lot of knowledge, but a Great teacher is the one who knows how to impart that knowledge.
@Analyst-hk8dq9 жыл бұрын
what a gifted teacher-from an admiring colleague
@mangarific14 жыл бұрын
The way he stitches together a beautiful and engaging narrative with such enthusiasm is incredible; I wish I was in his biology class
@tillinvite8 жыл бұрын
One of the best lectures i've ever heard, explained so well that even i understood most of it.
@oldmonk68447 жыл бұрын
Watching Dr. Lander is like a therapy. I almost feel like I am watching a documentary.
@paulwary4 жыл бұрын
Wow, this is so dense with information, presented so well your barely realise you're absorbing it. Conversational without a superfluous word.
@frankchris073 жыл бұрын
Were was this guy when I was in College. My word he makes it so interesting that I have no problem following him.
@ihavemanyobsessions9 жыл бұрын
Just one thing: Rosalind Franklin didn't show her photos of DNA's crystal structure to Watson and Crick. Wilkins showed the pictures to the two men without her permission, and her role in discovering DNA's structure wasn't really acknowledged until a while after she died.
@tugoriba42797 жыл бұрын
ihavemanyobsessions he corrected that later in another lecture
@decocatani5 жыл бұрын
Exactly! And this happened because she was a woman. The years showed that people like Watson, despite his brilliant work on DNA, are a shame to science. In my classes I always bring the name of Rosalynd Franklin as one of the real key minds behind the discovery.
@iraqi36122 жыл бұрын
Leave the shape and color of the tree and focus on getting wood
@hussainrazik12516 жыл бұрын
These videos are timeless and valuable with his lectures of clarity and getting his students actively involved
@AleifrLeifrson12 жыл бұрын
This guy is so great. I usually find it very boring when lecturers talk about history and lab techniques instead of the actual biology of the things, but he found a way to do it really quite interesting. =)
@ali183984 жыл бұрын
Just superb! I miss my university days! Professors like him are pure gold!
@MuhammadAfzal_97374 жыл бұрын
I always used to think that why MIT is number one in the world. Then I started watching your videos and realized that MIT has Eric lander. 💖💖
@Roedygr6 жыл бұрын
The was a wonderful presentation. Usually DNA presentations tell me the same old basics. This one told me all sorts of things I had never heard before, all with crystal clarity.
@horizon2reach5617 жыл бұрын
I liked his interpretation when he calls DNA a Boring molecule! I will never ever forget that for the rest of my life.
@matthewbartsh91672 жыл бұрын
That part seemed to me to make no sense. Who cares whether the bases only differ slightly. Any difference is enough to encode information. Boringness shouldn't come into it, I would have thought. What bearing does that have on whether it is the "transforming principle"? Does he mean those scientists were subpar? If so, why not let us know that? I wish Lander had explained what he meant. Edit: Also, so what if (a strange conclusion) "DNA has to be structural, given that it is boring" (or words to that effect)? Even if it were structural it could *also* carry heredity information, just as a load-bearing wall can have writing on it, or could encode information in different color bricks". So Lander seems to be attributing to those WW2 scientists a very strange and absurd line of reasoning.
@pietroxavier2008 Жыл бұрын
@@matthewbartsh9167 it was believed to be a solid structure who couldn't do much, so scientists thought it was boring and not really worth of studying then dedicated all their work on proteins.
@SK-ik8hn7 жыл бұрын
This was just awesome. Humbled by this teacher!
@cookingshooking31117 жыл бұрын
the bestest biology video i have ever seen
@ksbalaji12872 жыл бұрын
Thank you, Dr Lander. An amazing lecture! This has got to be the best way to teach a subject.
@existentnomad94774 жыл бұрын
These are marvellous lectures with an enthusiastic lecturer. Thank you for the open content
@neillinneball8 жыл бұрын
What an outstanding teacher. Terrific
@aliciathomas43156 жыл бұрын
This man is such a great lecturer! Thanks, MIT!
@kiberenigestsebez66333 жыл бұрын
Brilliant teacher. These kids are lucky to have this man. I could not find other lecture of his.
@biprodevsarker50473 жыл бұрын
“Spanish influenza epidemic was the worst flu ever.” Corona virus: Hold my RNA strands
@labronewalker75234 жыл бұрын
I love the sdcc skepticism part. I laughed so loud the librarian came over and warned me then I show her. When she laughed her colleague gave her a scornful look.
@kanusharma96174 жыл бұрын
I wish I could attend his lecture one day. Thank you sir for an amazing lecture. Unforgettable experience.
@preethyabraham21673 жыл бұрын
Oh my goodness!!! The best lecture I have heard... Blessed are u students of MIT
@nastushkkka8 жыл бұрын
это искусство, так лекции проводить, настолько интересно и понятно👏👏
@studentmedicosi82223 жыл бұрын
just awesome. Inspiring and motivating,,, World needs teachers like Eric Lander
@adamdaesen12 жыл бұрын
This lecture is an excellent introduction. Thank you Dr. Lander and MIT
@leonellumogdang73133 жыл бұрын
I hope Eric Lander will do more Lectures in Molecular Biology and Genetics. I just love the entire lectures. I keep watching the video since 2014 untill now.🙌
@stefanszczepanski896910 жыл бұрын
Thank you for these fantastic videos.I keep watching them all, and its flowing.
@iamderah5080 Жыл бұрын
God. If you were my teacher. I would have found the cure for HIV or Cancer. Such passion is contagious and transferable.
@priyankashukla37256 жыл бұрын
Happy Teacher's day, sir thank for enlightening us. superb lecture
@johneyon52575 жыл бұрын
excellent teacher - vivid & colorful explanations
@raghavgarg44576 жыл бұрын
Eric lander sir is best in biology the main real information provider
@Param_Sir2 жыл бұрын
I'm very much inspired by you Sir @MIT the way of delivering information is so fantastic that I am feeling it as live.🙏🙏🙏🙏🙏🙏
@nagajyothisireeshapemma37524 жыл бұрын
Excellent teaching methodology by Eric lander
@bernardoabreu49105 жыл бұрын
Brilliant. You have passion, and that's all.
@user-or7ji5hv8y3 жыл бұрын
Wow, what a great lecture. Finally connected the dots of why, for me.
@maxra423 жыл бұрын
Just awesome 👏 Such a brilliant teacher....
@sherlockholmeslives.16055 жыл бұрын
This guy is brilliant!
@elliotcoughlin1425 жыл бұрын
Amazing! Great teaching style!
@utsavbiswas53023 жыл бұрын
Brilliant teaching!
@humbertoluebbert79685 жыл бұрын
Thanks for sharing: extraordinary Teacher!
@q2breath4 жыл бұрын
1st: I could listen to Mr/Dr Landen 4ver!!!😃 So inspiring, so clear; I find myself feeling carried away, humbled, and absolutely jaw dropped by the level of clarity, and this genuine, positive approach, that brings a fresh breeze in every lesson that I watched. Simply fantastic. 2nd, I can't still wrap my head around the fact that Franklin's image of the DNA molecule was key to deciphering its structure, but then only the two guys received the 1962 Nobel Prize for their work. I am beginning to wonder whether winning the Nobel Prize in any scientific field is still really relevant, considering how much research they miss out from non-white and non- predominantly male labs around the world. I'm starting to feel quite depressed about it... IDK. I hope I will be able contribute to change this someday. (We got to do something about it, any ideas you geniuses out there?)
@niemand26227 күн бұрын
38:20 "That two such pygmies cast such giant shadows shows how late in the day it is." - Erwin Chargaff
@lordzlordz10 жыл бұрын
Eric Lander is the best.
@aladinndrake1106 жыл бұрын
Reminds me of Prof Diamond. Another like Eric Lander. Out of this world!
@cheddyoptimist1183 жыл бұрын
This is a fun history lesson with a some molecular biology anecdotes :)
@leminrunner8396 жыл бұрын
this is the way science should be taught 👍👍
@jin_wuu3 жыл бұрын
Довольно интересная лекция,мне понравилось,спасибо. Препод просто шикарный лектор!
@johnhammer86684 жыл бұрын
I love this professor.
@TheJTK1234 жыл бұрын
I love this Professor
@decocatani5 жыл бұрын
Brilliant lecture!
@mohamedabdelhady86185 жыл бұрын
this is very enjoyable !!
@tonyalan30704 жыл бұрын
He makes me wanna study biochemistry more and more
@akshaybhilwadecoep10 жыл бұрын
This is awesome!
@thex5772 Жыл бұрын
This is so beautiful.
@salvadorhirth16414 жыл бұрын
What a superb lecture, Professor! I'd like to share a hypothesis for the mechanism of huntington's disease: I believe that the inadvertent methylation of the carbon 5, followed by spontaneous deamination of cytosines in CAGCAG triplet repeats form one or more stop codons TAG and when a certain threshold of the formation of stop codons exceeds the DNA glycosylases capacity to repair errors, truncated proteins will be produced and possibly causing the formation of peptides that could interfere with the nuclear pore complexes so that the truncated proteins would get stuck across and in the vicinity of the nuclear membrane; the same transformation of cytosines into thymines in CGA triplet repeats could produce stop codons in the neurons of Parkinson's patients; maybe this phenomenon is the primordial cause of other neurodegenerative diseases; do you think that ( provided my suppositions are correct) DNA methyltransferase inhibitors, like azacytidine and decitabine, could delay the onset of such diseases?
@wadnikanet91642 жыл бұрын
Awesome lecture!
@ztpan75873 жыл бұрын
Wow! Phew!! Lander has put so much of himself into the lecture he looked exhausted...
@HafizahHoshni11 жыл бұрын
Thanks! Excellent lecture!
@shaochiwang6518 Жыл бұрын
Great video
@Victor603618 жыл бұрын
Gsus!!!! It's absolutely awesome!!!! So cool
@dantescanline4 жыл бұрын
I really wish this full class was available as uncut videos in order, rather than being suplements to a text-based online class.
@sesilyogkushses34142 жыл бұрын
This guy is awesome!!!!
@hemungkapoor20003 жыл бұрын
Thank you so much mit
@user-jl1un2ze3t5 жыл бұрын
When wrote thesis work with citations on Eric Landers articles and after looked in Open MIT Lecture :^D
@johntindell95916 жыл бұрын
he is an instructional master.
@nainasangma41697 жыл бұрын
he is just awesome
@swadeshtaneja35123 жыл бұрын
Excellent lecture
@1998miso8 жыл бұрын
Amazing !
@MrPopikeyshen7 жыл бұрын
ty for you lectures
@UCZx48kBoTg9O3 жыл бұрын
39:16 What do you do in England when you make a big discovery?
@x0ltrix Жыл бұрын
This is the nice thing about going to a school like MIT "You can ask Meselson down the hall about how he proved the semi-conservative model". You can have a chat about the very thing you learned in class with the guy who actually discovered the thing lol
@gudlakalkish34923 жыл бұрын
he is a good storyteller actually ...!
@sondosdohidi873910 жыл бұрын
Awsome ..!
@priyankadube18886 жыл бұрын
Thank you so much sir :)
@0623kaboom9 жыл бұрын
Feet up feet down assay is about showing a difference on a macro scale of some obvious change ... in this case dead or alive ... active lethal virus will kill while a non-lethal one wont kill ... ie the animal (rat) is either alive (feet down on the ground going about its life) or Feet up (dead no movement) Could this type of experimentation be used on a cell that has mutated (ie cancer) and find a way to see HOW it has mutated when compared to a healthy cell of similar or identical function?
@jalgas9210 ай бұрын
Anyone knows where to find Brice Huang’s lecture notes?
@SYEDNURULHasan178911 жыл бұрын
why excerpt ??kindly upload the full lecture.....
@prashantkumarparmanu7 жыл бұрын
thanks sir
@humeeayisha31995 жыл бұрын
I just didn’t likeDNA topics just because I thought it wasn’t interesting,and hey I just realized it’s fun.thanks you are not just a best ,I have found a father.❤️
@usamashah47372 жыл бұрын
I from Pakistan but it seems to me that this uncle seriously genius he teach well but I wish could understand 😕 his lectures ❤🇵🇰
@computerarchitecture94807 жыл бұрын
This is 2 kek . Very nice (y)
@mukund17585 жыл бұрын
I wanna ask something .... did anyone learnt this in high school like I did ?
@error_in_the_matrix44733 жыл бұрын
why dna is antiparallel ?
@nishanthsekar67605 жыл бұрын
I have a doubt.... Griffith worked with deadly microbe (during his period) how did he protect himself from pneumonia, there's no antibiotic or vaccine during that time????
@theowleyes074 жыл бұрын
Look in the NCERT Book
@nomikabiotech81574 жыл бұрын
This instructor's face really reminds me of professor Mario Lebendiker from the Hebrew University in Israel😊
@2704samir3 жыл бұрын
I wish i had studied at MIT
@tylerb2739 жыл бұрын
does anybody know what he meant by the "feet up feet down assay"?
@mrsHimalayan8 жыл бұрын
+Tyler Bernstein feet down - mouse is still alive feet up - mouse is dead
@tabrejkhan90296 жыл бұрын
excellent explain
@tabrejkhan90296 жыл бұрын
excellent explain
@tabrejkhan90296 жыл бұрын
excellent explain
@kenya254familylove4 жыл бұрын
Feet up means dead feet down means alive
@abijithsasikumar599011 жыл бұрын
if you were my teacher. im sure i would have scored full on my exam
@anilkumarsharma12054 жыл бұрын
all the world wide scientists are required to mix the genome of oil plants of all types at once which give a tap supply of oil
@Fortynienq124 жыл бұрын
Mistakenly clicked,ended up watching whole video
@KJKP6 жыл бұрын
He is having fun and jokes... but nobody laughs. Relax, people. Enjoy everything everywhere.
@4umata6 жыл бұрын
Phage is not a good idea?? A lot would beg to differ sir!
@ricasiogaming78733 жыл бұрын
I actually watched this entire video instead of doing my biology homework lol.
@tushar64733 жыл бұрын
To which class he is teaching?
@aasthade53513 жыл бұрын
I'm from india ...I'm a PCB student of class 12 .....how can I join MIT .... anyone suggest me plzzzz .....
@mitocw3 жыл бұрын
mitadmissions.org/ Good luck!
@mehdimajidi87557 жыл бұрын
genetics always remains amazing and enjoyable but i wish if only we could find out how to being independent about the byproducts, i mean there can be a vast disapproval against what is made up by genetic modulations. anyway thank you. i pay tribute to your attention to the science!!