Does PREVAGEN really work? NEUROLOGIST Explains

Рет қаралды 30,943

Күн бұрын

Prevagen is a popular (and expensive!) supplement claimed to improve memory. Is there enough evidence to support this claim or is Prevagen a scam? In this video, double board certified neurologist Neurogal MD evaluates the evidence.
Timeline:
00:00 - Introduction
01:03 - Active Ingredient in Prevagen: Apoaequorin
03:41 - Is there evidence that Prevagen improves memory in humans?
06:51 - Is Prevagen safe?
07:07 - My final conclusions about Prevagen: Scam or worth the cost?
Disclaimer:
This video is provided as an informational resource only, reflects my opinions only, and does not create a patient-physician relationship. This video does not constitute medical advice and is not an alternative to medical advice from your physician. Please speak with your physician before starting any supplement.
REFERENCES:
www.ncbi.nlm.nih.gov/pmc/arti...
www.sciencedirect.com/science...
www.prevagen.com/wp-content/u...
pubmed.ncbi.nlm.nih.gov/26878...
pubmed.ncbi.nlm.nih.gov/24768...
pubmed.ncbi.nlm.nih.gov/23470...

Пікірлер: 114

@JulieAiken Жыл бұрын

Thank you for this analysis. I have significant brain damage and am always looking for something to improve my short-term memory. (I can't remember my address or phone number -- both new since my brain injury 3 years ago -- so I'm keen on finding any relief!) But my own research into Prevagen led me to the same conclusion you have. Exercise, playing a musical instrument, good sleep, reading daily, all kinds of puzzles (crossword, jigsaw, brain teasers, etc.), coloring/painting/doodling, meditating, visualization of healthy neurons... a lot of things help me, but I've given Prevagen a pass. Good to hear I'm probably not missing anything!

@anm0r 8 ай бұрын

Hi, can I ask you how you feel today in terms of memory? If it has improved, could you tell me what kind of things you have done or taken that you have noticed improvement? I ask you please from the bottom of my heart, a very dear one of mine is having problems with it.

@JulieAiken 8 ай бұрын

@@anm0r I have made a ton of progress on improving my short term memory AND creating systems to make up for memory deficits. I'm compiling a list for you -- it may take a another day because I'm pulling 3 years of notes and journal entries together. But hopefully there will be something that will help. FIRST I would suggest getting a physical or talking to their doctor. I had a brain tumor; there are tons of physical problems that can effect memory and cognition, and many of them are very treatable. If you know what the issue is, then the tips I'm going to send, including a few book references, may be helpful. Love to you!

@anm0r 8 ай бұрын

@@JulieAiken Hello, thank you very much for your reply!!!! :'D Currently, we have not been able to go to a specialized doctor, only to a general one, this person I am talking about at the moment I feel that she is very stressed, besides that for a few years now I feel that she has not been sleeping perfectly well. I am almost sure it is because of that lifestyle of stress + not sleeping well :( but the hours of sleep are because her day ends at about 12 a.m. and she has to wake up at 7, but sometimes it is at 5, sometimes at 6, or sometimes she does not sleep at all. Sorry for the inconvenience, thank you very much from the bottom of my heart and have a nice day!

@consumerofmicroplastics Жыл бұрын

Glad to see you post again, very informative as always!

@classiccinemac9480 Жыл бұрын

Anna!!! So glad to see you back!! 🙌 Really missed your videos as it has been a while since you have uploaded! Watching this has definitely been very interesting about Prevagen as it is something I have heard of but not too familiar with. Definitely came across it at CVS but you sharing more info is definitely really engaging and interesting. Also hope the holidays are going well and so nice to see you back Anna! 😊

@neurogalmd Жыл бұрын

Thank you, Mac! It's great to be back. Hope you are having a wonderful Holiday Season yourself! :o)

@mugsiex Жыл бұрын

Soooo...good to see you posting informative and entertaining content again! Yayyyyyyy Anna aka YOU!

@neurogalmd Жыл бұрын

You're the best, Tim!!!

@Ded-Ede 7 ай бұрын

Thank you so much for this report about this supplement. My mom takes it. I was about to purchase it but I decided to search for feedback and analysis. Before my diagnosis of a brain tumor and it’s removal, I’ve had bad memory for a decades, but not knowing the cause. But since the surgery, my memory has improved, but it is still bad.. I’m going to get a memory test to get confirmation and a baseline test. My neurologist also recommended CBD treatment for pain because the current prescriptions are questionable but little results. I eat healthy. I can definitely improve my sleep and increase my exercise. I daily walk and sun. I’m learning Spanish and doing brain and fun games to. I’m seeing improvements but I’m retaining some of what I’ve learned and need trigger to remembers the other half. My mom 20 years older than me have better memory.

@dandefoe Жыл бұрын

Thanks for this educational video, Neurogal MD. Your organized and easy-to-understand presentation should help many sort through the chaff and navigate more safely through the fog of the hugely profitable supplement industry. I liked the way that you marched through the study, pointed out the "strengths" and limitations, offered and explained your conclusions, and, importantly, gave your recommendations for healthy and more economical options - eat better, good rest, and exercise. Another winner, Neurogal MD. Thanks.

@dustinrupert620 Жыл бұрын

I've been taking prevagen for over a month now, and i am feeling like it is gradually clearing away blockages in my memory and access to my brain, and concentration. I will be very happy if i see substancial change by another month or two. If so, then it is cheap! (No, i don't have enough money for daily life, but if i feel my brain is healed, it's worth owing money for, to be worried about later).

@peterskowronski5974 Жыл бұрын

Good analysis Dr. thank you. So, for those of us who are on the north side of 50, do you have any recommendations that would help achieve the effects promised by Prevagen? what foods, supplements, and or exercises (physical or manel) could help? Thank you again for your public service.

@privatsitazen Жыл бұрын

I found this video to be very clear and concise. Thank you!

@mikemarcus4190 Жыл бұрын

Thank you for your thorough and unbiased information on Prevagen. I have been thinking of trying it or another like it. Your video helped me to make an informed decision Thanks Again

@neurogalmd Жыл бұрын

Glad it was helpful! Thank you for the positive comments!

@angelirohival6270 2 ай бұрын

Wow! I had considered buying this. You just saved me a good chunk of money!

@FW-jq1ox Жыл бұрын

You had me at 0:28 - Quincy Bioscience. A cursory review of some companies is enough to assure me that the product is crap: too many Elizabeth Holmes-types out there.

@a0-0g 9 ай бұрын

Thank you so much for your investigation on this! Great information.👍🙂

@rballersUnited Жыл бұрын

Thanks for doing this research for us and providing the truth.

@whatszup1206 Жыл бұрын

Would love to see more content Anna!

@keithlevkoff8579 9 ай бұрын

That was a remarkably detailed and concise analysis of the available facts... I had been wondering if there was any real positive effect with Prevagen or not... I'm not in the medical profession but I do have quite a bit of background in science and testing... I had noticed that, in one or two interviews, when asked if they had study results, the answer always seemed to be something that was equivalent to "we have lots of positive anecdotal evidence". That's not to say that it doesn't have actual benefits of the sort that only a small percentage of people see them. However... when you mentioned your red flag about their narrow choice of the particular metric they chose... one thing came to my mind... To me it sure looks like they cherry picked that result from a long list of results that were statistically null. (It would be somewhat interesting to know if there were any equally narrow negative correlations they neglected to mention.) Anyway... awesome video...

@GeraldLewis-nk4ql Ай бұрын

I want to go back to school cuz I flunked in Life for many years now cuz of memory issues that needs attention to get fixed as soon as possible Now and Forever and Amazing ly AMEN.

@RealMattHaney Жыл бұрын

Another excellent video Neurogal!

@emphasis20 Жыл бұрын

Doctor Neurogal, appreciate the videos. I am curious if you would be interested in making a video about NFL quarterback Tua Tagovailoa and his repeated concussions this season (3 so far). Maybe about discussing the short and long term effects and anything else relevant.

@DBD-MOGUJING 12 күн бұрын

Thank you so much, I almost paid $145 for the super upgrade

@gwgwgwgw1854 Ай бұрын

Just the info I was looking for--thanks!

@will.a.benjamin Жыл бұрын

Good to see you again Anna 😊

@neurogalmd Жыл бұрын

Thank you! 😃

@ArmyScoutMom 3 ай бұрын

Excellent analysis thank you!

@ianshirreffs5604 Жыл бұрын

Thank you for the content 🙏 This was really interesting.

@neurogalmd Жыл бұрын

Glad you enjoyed it!

@glazar102170 4 ай бұрын

Thank you Dr. Neurogal!

@TheThinkersBible 7 ай бұрын

Thank you for this timely analysis. I was hoping Prevagen might be useful for someone I know but mental stimulation seems to be a better option. And now 2 government agencies (FTC and the State of New York) are suing the makers of Prevagen for fraud.

@scarolinispicks4073 4 ай бұрын

Hmmm. Mainstream media is first marketing it then goes onto air info about lawsuits on cbs & mbc AND govt agencies (corrupt) & the state of NY (ultra corrupt) DONT want people taking so it seems I should try it. 🤣

@gsssprocket 27 күн бұрын

USUALLY WHEN THE BIG GUYS THAT HAVE HANDS IN THE PHARMA MONEY POT, SUE OR RESUT OR DEFEMATE,, THERE IS SOMETHING ABOUT THE PRODUCT THAT IS VERY WORTH WHILE OR HAS POTENTIAL

@juntruck1 Жыл бұрын

Thanks! Would you consider preparing a review for Aller-7/NR-A2/Triphala? I would also like to hear what you think about Heantos TCM, Nicotinamide mononucleotide, NAD+, Niacin, Pyrroloquinoline quinone/methoxatin, and Piracetam.

@neurogalmd Жыл бұрын

I'll check these out!

@zachocracy Жыл бұрын

I'd like to see one like this on Aducanumab which required an accelerated approval process and ignoring adverse events, as well as zero efficacy.

@Bluviolet7392 Жыл бұрын

Thank you so much for this informative video.

@sncnutrition7118 Жыл бұрын

RAZADYNE aka Glantamine. Your thoughts on it. Thanks . Also Lions Mane , Alpha GPC would be good to see your review on all 3 of these products.

@michaelclaffey6688 Жыл бұрын

Kratom green vein Malay Any thoughts Doctor? Love your videos too!!

@Ax.DaEdge Жыл бұрын

@Neurogal MD Can't K2/D3 do the same as Apoaerqoritin (?), in terms of "Calcium metabolism" in the Brain?

@christhecrank8132 Жыл бұрын

Hello Dr, do you have any book or books published in market?

@AhmedKamalAbdelhalim Жыл бұрын

What's the best supplement you would recommend for memory and sharpness?

@arnabdas4790 Жыл бұрын

Please make a video about bacopa monnieri herb for cognition.

@Renee302976 Жыл бұрын

I’m 47 years old, and I’ve just started taking Prevagen for 3 days. I’ve already noticed a good difference in how I am able to retain and comprehend information. Am I imagining this 🤷🏽‍♀️

@JesusChrist-Gives-Eternal-Life Жыл бұрын

I am 41 but have cognitive issues and was sent Prevagen by accident by an Ebay seller. I took it and feel like I am noticing a difference, but I do know placebo effects are real too.

@JesusChrist-Gives-Eternal-Life Жыл бұрын

@@elperrroverde 😂😂 That was funny! Thanks!

@alanbrendaarcherareviewing4090 9 ай бұрын

@@JesusChrist-Gives-Eternal-Life😊

@jummansheikh739 Жыл бұрын

need more videos on conciousness !

@Bobsbigbuoy Жыл бұрын

Thank you!

@minhdinh3942 Жыл бұрын

What about l-tyrosine, do you think that helps brain function?

@jamiereife5581 Жыл бұрын

I’d noticed my husband having issues so I bought him a bottle of prevegin. It was quite expensive so I didn’t buy the more expensive version. And I asked him to please at least take the bottle. I noticed an improvement in him and I think he did too. He finished the bottle about a month ago and this morning he did something kind of odd. So I am going to buy another bottle for him. I was wondering if there is anything less expensive I might be able to buy for him or feed him that would have the same effect

@Finians_Mancave 11 ай бұрын

Try Magtein (Generic name is Magnesium L-Threonate. About $25 for a 4-6 wk supply. There is a lot of positive clinical study info on it, so I suggest you look it up yourself). I first tried it out years ago as I was already taking a daily magnesium supplement due to chronic migraines. I'd read that Magtein was a "special" form of magnesium that crossed the brain barrier, unlike other magnesium. Long story short, after only two days, I suddenly felt more alert, clear-thinking. That was 7 years ago. Today my Dad is 90, sharper than ever mentally, and we both still take Magtein as part of our daily regimen. The recommended dosage is 3 capsules a day, but I recommend just taking two (one in the morning, and the other just before bedtime) at least in the beginning. BTW, two of my friends have replaced melatonin with magtein as a sleep aid -- that is the other major benefit. But hey, don't take my word on all of this. Buy a bottle and have two or three people in your family try it for just a week (At its core it's just a magnesium supplement, so most people can take it without any noticeable side effects). I'll be very surprised if they don't see some dramatic, positive effect!

@Ded-Ede 7 ай бұрын

3:16 is the lining that covers the brain part of the blood brain barrier? Because I have part of my meningi remove due to tumor that cracked my skull. So can substances have easier access to my brain due to this insult trauma?

@JohnGraver 3 ай бұрын

Hello Dr Hana I am very concerned with what I feel is a decline in my memory. Names I have always had a problem with but now directions to places I have gone many times, appointments, even information from zoom classes I take to try and stay sharp. I have tried a few supplements and the latest is Dynamic Brian which I have only been taking for 2 weeks. I would love to know from a Neurologists point of view is there some supplement that can help me or am I destined to have a memory slide. Thank You John

@justpar2012 Жыл бұрын

It takes time for a supplament to be beneficial. I'm going to use up the bottle then decide to keep/stop it. Might take 6 months but any gain is acceptable for me to continue.

@cathyveldhuizen1750 Жыл бұрын

Are you still using it? My 90 year old stepdad swears by it, so I just started it today.

@michaelt7805 9 ай бұрын

Quincy Bioscience has agreed to resolve the claims that it misrepresented its Prevagen products as supporting brain health and helping with memory loss. Under the terms of the settlement, eligible purchasers can recover refunds of up to $70.Sep 21, 2020

@Ded-Ede 7 ай бұрын

2:34 so what should we eat to be transformed into what we need. Cod liver oil?

@holistichealthcare101 Жыл бұрын

Thankful for this bit of information! Two important facts I’m picking up on thats stated here.The main ingredient is created in a lab and is genetically modified. 🚩 Then our bodies process of digestion limits what we can ABSORB. The key here is oxygenation of our cells which we enhance with daily movement to get the heart pumping! Also working on cleaner eating and detoxification of our body from all the chemicals in the environment. If our drainage pathways get cleared the body can do its job. 🫶🏼 Heathy Fats namely DHA 1000 mg is what helps me. Just sayin. 😊

@chrisvincent8123 10 ай бұрын

Based on your synopsis and my knowledge of biochemistry, I doubt if Prevagen is effective. The two main obstacles being digestive destruction of the molecule and its probable inability to cross the blood brain barrier.

@timothy4131 5 ай бұрын

Maybe you could help me with a question please I would appreciate an answer from you very much I have congestive heart failure I am 54 years old and I am constantly forgetting stuff I mean I could take a medicine at within 20 minutes I totally forgot I took the medicine or sometimes I think I took something but I didn't is this what they call cognitive decline and is it linked to congestive heart failure

@louisevad6091 5 ай бұрын

Thank you Doc. I'll be skipping this supplement. I'll be working on how to decrease my calcium score.

@joshtaylor4583 Жыл бұрын

So what does repair/restore memory then?

@zachocracy Жыл бұрын

Prevagen funding their own study isn't much different that fda's yearly funding being 65%+ from pharma companies, just in user fees alone. They seem to market euas and create novel accelerated approval processes rather than actually doing their job to serve as a safety check.

@theluckyman74 Ай бұрын

Some studies found magtien the magnesium for the brain does improve memory i think Dark chocolate can also help the brain

@briandspohn-hm7bi Жыл бұрын

I am watching now.

@micah.80665 9 күн бұрын

Thank u for this video. Alz/dem is on both sides of my family so I’m TERRIFIED me, my mom or my sister will get it. I was my maternal gmas guardian in my 20s, my paternal gpa died from it in my 30s, then recently in my 40s I was my fathers in home caretaker until he passed from it. It’s all I think about now. Who is next. My mom? Me? My sister? Will my son have to see me like I saw my father? I figured this was too good to be true but I hoped it could somehow help

@GeraldLewis-nk4ql Ай бұрын

I honestly have ADHD issues for many years now I have also Have memory issues that needs still need to be addressed and good luck of Justice for me and that's the point though

@bobcrain9045 Ай бұрын

For those who are worried about the safety profile of the current Alzheimer's drugs there is a drug about to finish a large P3 study later this year that has had outstanding safety results and in P2 trials showed 47% of patients increased cognitive function, with a additional 23% of Alzheimer's patients stabilized over 12 months. This drug is being tested by Cassava Sciences and has not just one, but two large P3 trials with over 1900 patients. Both trials will be completed by the middle of 2025.

@SacredOwl Жыл бұрын

is it true that K2 pulls calcium from the blood?

@privatsitazen Жыл бұрын

K2 with k7 should be taken with calcium for absorption efficiency

@ipkiss1162 3 ай бұрын

If this is bunk - what can we take to support optimal brain function ??????

@keng7758 Жыл бұрын

Great video, this company spends a lot on advertising so it’s interesting to see that you don’t feel it’s effective. I’d be super interested in your assessment of taking NMN or NR to improve NAD+ levels in our tissue and blood. I’ve been in it for 15 months and while I believe in the science behind taking these precursors, I don’t have any benefit to report (unlike many who claim energy and endurance benefits).

@zachocracy Жыл бұрын

Excellent clarification of in-vivo, in-vitro for casual watchers. This is why the LipidNanoParticle encasing the CV shot worries me. They use a platform approach assuming it stays localized, but LNPs were originally created to bypass otherwise impermiable layers like the BBB and notably found throughout the body after 6 months. Idk how that platform is then possible.

@456MrPeople Жыл бұрын

You're right but mRNA, which is encased by the LNP, is highly immunogenic so it is rapidly broken down by immune cells in your body if it is found outside the cell. The LNP is used to deliver the mRNA to your cell's ribosomes, which are inside the cell, so the epitope of the COVID spike protein (only the part that makes your immune cells produce antibodies, not the whole spike protein) can be presented to your immune system. Overall, I doubt you have anything to worry about regarding COVID mRNA vaccines, apart from the very small chance of myocarditis, which is also lower in both frequency and severity compared to the actual virus.

@shoubledouble6603 4 ай бұрын

I can’t focus so I bought this thinking it would make me focus better I guess not.

@type2life396 Жыл бұрын

Do you recommend any supplements at all for brain health ?

@whitedove4072 11 ай бұрын

Lions Mane is very good. Also. MCT oil is good too.

@DerekDavis213 7 ай бұрын

@@whitedove4072 There is no good scientific evidence to support the claims of Lions Mane efficacy.

@j.fnorfleet1969 Жыл бұрын

Hello beautiful, do you have any information on cerebrolysin for me?

@vamama100 Жыл бұрын

What NORTROPIC SHOULD WE USE?

@briseboy Жыл бұрын

Several have been suggested including by our psychiatrist here: Exercise, novel experience, sufficient sleep; essentially, creation of alternate associational routes to memory, as in learning attentional skills as musical facility, and reading & attending seminars on complex subjects. Formal learning- classes - in both physical and mental skills. Avoiding arousal chemicals that brain cells adapt to through altering production of neurotransmitters/modulators, certainly restores normal circadian variation, as well as offering valuable opportunity to notice, attend to, change interoceptive associations, which cognitive issue has been insufficiently explored by media outside abstruse research. Do NOT make a life-practice of immersion in social media anecdotal assertions, which has not only retarded knowledge, but has induced reversion to medieval-like misattribution.

@starman4800 5 ай бұрын

What is the best supplement for your memory??

@jc4evur661 Жыл бұрын

Prevagen makes some pretty bold claims in their commercials...especially so since they're not FDA approved Give your money to a charity...there you should see some benefits.

@DerekDavis213 7 ай бұрын

If you give money to a charity, they will give or sell your name to many other charities. Then your email or home mailbox will be flooded with requests for money. And most so-called charities are bs.

@johnbassett5407 Жыл бұрын

The health supplement industry is massive. It makes you wonder what percentage of their products actually work.

@captainsouth4460 Жыл бұрын

probably 0%

@jameswilson5165 Ай бұрын

Once again, it sounds like elderly people are being "Taken for a ride." This is such a shame in so many ways. Alzheimer's is one of the diseases that can test your faith in a benevolent God. It's horrible to watch a loved one decline to the point that they will no longer recognize who you are even though you have been married for 60 years.

@JustMe99999 Жыл бұрын

Just like most supplements - total BS.

@rainbow20112011 Ай бұрын

You are one hot neurologist.

@davidedmundson8402 7 ай бұрын

Thanks for saving me $40 to $90 a month!

@FrankJones5534 2 ай бұрын

It made me have seizures.

@KenjiEspresso 10 ай бұрын

KZfaqs channel my dear. ;)

@josieb1991 Жыл бұрын

I would really like to find someone who is not a doctor to review this supplement. I will keep looking. I am not researching for myself but for someone else.

@rickvassell8349 Жыл бұрын

I say try it, see if it works for you. I know people that swear by it.

@Fitwm 24 күн бұрын

Bi Done Endorsing

@dougadams9419 2 ай бұрын

No, it doesn't work. I'm 72 and have been taking the generic version for a month and I notice no change in what is claimed. I always doubted those TV commercials. The Federal Trade Commission and New York State Attorney General have charged the marketers of the dietary supplement Prevagen with making false and unsubstantiated claims that the product improves memory, provides cognitive benefits, and is “clinically shown” to work. And it's damned expensive. I bought a small bottle of the generic Equate from Walmart (for about 1/3 the price) and here are the ingredients. Coffee (coffee arabica) Fruit Extract 100 mg. phosphatidylserine 100 mg. The phosphatidylserine supplement claims to support symptoms of anxiety by reducing stress, regulating mood and encouraging your body to relax. It claims to manage anxiety by balancing cortisol levels in your body. Cortisol is a hormone that responds to stress.

@pythonoptic 9 ай бұрын

Would be interested in testing our nootropic gummies?

@Laljack564 Жыл бұрын

I tried prevagen for frw months it improved my short term memory for few weeks. Then it caused voices in my head which caused many problems. It did not let me sleep at night. I got off but the stupid voices in my brain stayed with me. I hope this stupid product is taken of market and the company is sued.

@darryldanzinger9996 7 ай бұрын

Do you still hear voices in your head?

@hughmacdonald3595 11 ай бұрын

Lol. At least 8:00 too long.

@ronpetrus7676 11 күн бұрын

If it works so good why didn’t they put Biden on it …lol

@GeraldLewis-nk4ql Ай бұрын

I want to go back to school cuz I flunked in Life for many years now cuz of memory issues that needs attention to get fixed as soon as possible Now and Forever and Amazing ly AMEN.

@GeraldLewis-nk4ql Ай бұрын

I want to go back to school cuz I flunked in Life for many years now cuz of memory issues that needs attention to get fixed as soon as possible Now and Forever and Amazing ly AMEN.

@GeraldLewis-nk4ql Ай бұрын

I want to go back to school cuz I flunked in Life for many years now cuz of memory issues that needs attention to get fixed as soon as possible Now and Forever and Amazing ly AMEN.