Рет қаралды 64,367
New research suggests fasting & autophagy support the regeneration integrity of the gut barrier.
Support your Intermittent Fasting lifestyle with the Berberine Fasting Accelerator by MYOXCIENCE: bit.ly/berberine-fasting-acce...
Use code podcast at checkout to save
Link to show notes and research: bit.ly/2RCnAI2
----------------------------------------Show Notes-------------------------------------
0:00 Intro
2:05 The best way to enhance autophagy is with diet and exercise.
2:44 mTOR is the autophagy break and AMPK is the gas. AMPK also puts the break on mTOR.
3:25 These enzymes cannot be directly tested.
4:20 If your glucose is high in a fasted morning test, you may not be experiencing autophagy.
4:40 Your body upregulates APT with activity after your night’s fast. This increases AMPK and puts the breaks on mTOR.
5:40 mTOR is activated in the post meal window. This helps you body take the nutrients.
7:00 Exercise stimulates AMPK, as does intermittent fasting and taking berberine hydrochloride.
7:40 Paneth cells are key at releasing antimicrobial peptides which keep pathogens from entering.
9:40 Endotoxin/LPS (lipopolysaccharides) are found on the surface of gram-negative bacteria. Because of these, many of us with leaky gut have low grade sepsis after every meal.
10:44 Paneth cells and intestinal stem cells are intimately connected to the autophagy process.
12:20 Paneth cells control your intestinal stem cells. Stem cells help replenish and repair damaged cells.
14:00 Intestinal permeability can be tested via Dunwoody Labs.
14:22 Tight junction proteins are the mortar for your gut lining.
15:50 Dysfunction in your gut endothelium cross-talks with lung and cardiovascular endothelium.