Gerald S. Shadel Talk title: The “Age” of Mitochondria

Рет қаралды 17,824

Күн бұрын

Back to Basics Lecture series at the Salk Institute with Salk Professor, Gerald Shadel. Shadel is a professor in the Molecular and Cell Biology Laboratory and holds the Audrey Geisel Chair in Biomedical Science.
The talk title: The “Age” of Mitochondria

Пікірлер: 43

@DessicatedCadaver 3 жыл бұрын

Life is short, don’t waste time. The actual talk starts at minute 12:45, but doesn’t actually get going until much later, so buyer beware. I wish there wasn’t as much time wasted in all these yt videos - please do a favor to all viewers and always indicate in the comments when the ACTUAL CONTENT YOU CAME FOR starts, it would be much appreciated!

@Mr_Fission 2 жыл бұрын

From what I saw of this presentation, the whole thing is a waste of time. But yeah they spend a lot of time bloviating at the start.

@dinomiles7999 3 жыл бұрын

Dr. Jack Kruse, Dr. Ronda Patrick ,Dr. Jed Fahey, Dr. Abry DeGeay....

@dominictoretto-wc5cl 4 жыл бұрын

i am a big fan from the big range of fantastic research the great salk institute do. greetings from germany

@denniscerletti9454 2 жыл бұрын

Seed oils damage mitochondria.A 2002 study from Italian scientist measured the energy generated from mitochondria from4 fatty acids.Saturated animal fat produced 100% and was given the baseline.Mono-saturated fat was 115% is was surmised that it's molecule structure was such that the opening was in the middle of the molecule and was a easy snip to have 2 shorter stable saturated fats.Linoleic Acid/ Omega 6, the most abundant in seed oils, polyunsaturated fat, only produced 50% energy and Linolenic Acid/ Omega 3 only produced 20% energy.Study is sighted in Dr Cate Shanahan's book," The Fatburn Fix" also view Dr Chris Knobbe KZfaq videos for further understanding of the negative health effects of seed oils.

@aoifewest 2 жыл бұрын

Thank you for sharing

@Mr_Fission 2 жыл бұрын

That's excellent information. So you're saying that even Omega-3 PUFA restricts mitrochondrial function? I heard that it was good at stopping heart disease, but I didn't realize it slowed down metabolism. That's wild.

@JasonNoto Жыл бұрын

Seeds can go through the digestive system when they're not bitten into and pass through the digestive tract intact. An issue with making seed oil is that it could release salicylates oxalates and lectins, which can also be reduced when removing the peels, skin, bark roots and stems of plants.. in other words steering clear of that which damages the host plant or infringes upon the fruit growing. However fruit is designed to be eaten so that the seed can be spread by the consumer. The defense mechanisms are primarily for the host plant and so that the fruit can grow and spread the seed which is facilitated by a consumer, even though there are other ways to spread the seed such as dandelions or such as in coconuts floating in water to spread around wait

@bobleclair5665 2 жыл бұрын

The body is 7 years old, at about 7 years,every cell in your body has renewed, as good as or not as good as the previous cell , memory is important

@veronicaford5737 Жыл бұрын

No disrespect to the speakers but if short on time, start on minute 20 for mitochondria and hormesis

@medicalpanorama Жыл бұрын

Interesting talks. How do you define a healthy mitochondria? If you do, then, we can tell why innate immune system will clear the unhealthy ones.

@discardedvetdoc 9 ай бұрын

have you guys done any research into us desertstorm gulfwarilllness veterans? We are the long term study of these systems breaking down!

@clementmariostlouis6686 11 ай бұрын

Could the phospholipid of mitochondrion membrane be reinforced by beneficial fats to prevent circular Mt DNA to get out into of the cytoplasm of cell ?

@markfrank0924 Жыл бұрын

For every scientist, there is one who looks at why we love so long and how we might live longer. There are also researchers who say, well, that is so good as long as those who live longer are the ones we want to live longer. Research into living longer should begin with what we put into our pie hole. Imagine we have a 350 lb person who wants to be a professional tennis player and the coach never mentions weight is a factor in performance and as a result, unless the person is willing to stop eating and work out each day his "dream" of being a professional tennis player is just that, a dream.

@davedanny9053 2 жыл бұрын

Good stuff

@health-seeking 2 жыл бұрын

2 weeks on intermittent fasting and my crp gone from 14 to 6.9 I have severe ra and meds don’t work. Neither 20 years of different diets didn’t work.I am on methotrexate and cimzia. Fasting worked.

@Mr_Fission 2 жыл бұрын

Yes it does.

@davedanny9053 2 жыл бұрын

I love this

@bobleclair5665 2 жыл бұрын

45:25, when you were young ,you went home when you were hungry

@netto682 3 жыл бұрын

Very good🇧🇷👏👏👏

@Mr_Fission 2 жыл бұрын

Age, age, age. No, the biggest factor for a lot of the diseases these guys are talking about is diet. Alzheimer's has been suspected as being diabetes of the brain. There is a chance it's neurological dysfunction due to insulin resistance of the brain. The guy at 4:00 says that aging is by far the biggest factor for other diseases like heart disease and diabetes. Yeah that's bullshit. The biggest factor by far is diet. The more sugar and carbohydrates you eat, the more LDL oxidation and glycocalyx degredation that occurs, which leads to atherosclerosis and arterial plaque (heart disease). Diabetes is directly linked to insulin resistance, which is directly linked to carbohydrate and sugar ingestion. These guys are working on the noble cause of prolonging life by reducing mitochondrial dysfunction, but they're way off the mark on age being the main cause of disease. Diet is. There's tons of research available to back that statement up.

@davedanny9053 2 жыл бұрын

Nice