hepatocellular carcinoma

  Рет қаралды 26,159

Stanley Kim

Stanley Kim

Күн бұрын

The hepatocellular carcinoma is the most common liver cancer of which incidence is rising in the US. The common cause of this disease is non-alcoholic fatty liver, especially NASH (nonalcoholic steatohepatitis) as well as alcoholic liver cirrhosis.
When the cancer is liver-confined, patients can be cured by surgical resection or liver transplantation.
But when diagnosed in advanced stages, the prognosis was decimal in the past because traditional chemotherapy is not effective in this kind of cancer.
Thanks to recent advances in locoregional therapies and systemic therapy with immunotherapy drugs and multitargeted tyrosine kinase inhibitors, the survival rate has been imroving.

Пікірлер: 69
@VN-ux2ep
@VN-ux2ep 7 ай бұрын
My father was a well built 6 footer, just turned 65 a month ago. HCC was diagnosed with HCC in October 2022. Chemo was ruled out, surgery was ruled out. He was prescribed Lenvatinib capsules. Coped well until July. Became too weak for immunotherapy. Slowly grew weak and died peacefully on 07th October 2023. The hard truth is, once you have HCC, death is only prolonged, and whatever you do, it cannot be evaded. That's the hard truth!!😐😐😐😐
@meltoagee9999
@meltoagee9999 7 ай бұрын
During diagnosed HCC spread any other organ??
@VN-ux2ep
@VN-ux2ep 7 ай бұрын
@@meltoagee9999 No, that was the first thing the doctor did. Conducted detailed MRI and PET scan of the whole body, head to toe and spread was ruled out.
@India_uk
@India_uk Ай бұрын
Hi why he was not given chemo or radiation treatment? Also you mention he died 7 th October 2023 ? But he developed the HCC in October 2023 and cope until July don’t make any sense
@VN-ux2ep
@VN-ux2ep Ай бұрын
@@India_uk oct 2022 to oct 2023. That was a typo. About giving or not giving chemo, are you a doctor ? Don’t ask stupid questions.
@India_uk
@India_uk Ай бұрын
@@VN-ux2ep You just changed the date now you lied.. just admit you made a mistake in those date or writing a fake story you muppet Comments TOP Newest My father was a well built 6 footer, just turned 65 a month ago. HCC was diagnosed with HCC in October 2023. Chemo was ruled out, surgery was ruled out. He was prescribed Lenvatinib capsules. Cope well until July. Became too weak for immunotherapy. Slowly grew weak and died peacefully on 07th October 2023. The hard truth is, once you have HCC, death is only prolonged, and whatever you do, it cannot be evaded. That's the hard truth!! に に に
@stanleykim1924
@stanleykim1924 10 ай бұрын
ERROR: At 17:25, I wrote and said that the combination of nivolumab and pembrolizumab is used for the 3rd line therapy. Pembrolizumab should be ipilimumab. In other words, the combination of nivolumab and ipilimumab is correct.
@user-ir7zr1mu7w
@user-ir7zr1mu7w Жыл бұрын
교수님 영상잘보고있습니다 존경합니다 그리고 응원합니다 항상 건강하시고 복많이 받으세요
@stanleykim1924
@stanleykim1924 Жыл бұрын
For MRI scan of the liver, gadoxetic acid (Eovist) enhanced MRI is more sensitive than using gadolinium as a contrast because Eovist is taken up by hepatocytes, and excreted into the bile as well as in the urine.
@Onc-learning
@Onc-learning Жыл бұрын
Dr Kim, thank you for this video. Could you make a video on ALL?
@sajjadahmad3399
@sajjadahmad3399 Жыл бұрын
Excellent lecture Sir
@ayeayehla4869
@ayeayehla4869 Жыл бұрын
Thank you Dr. Very informative video. 🕯
@Disruptivepharma
@Disruptivepharma 7 ай бұрын
Thanks for good and compelete information
@mitanshusharma5944
@mitanshusharma5944 Жыл бұрын
Very Nicely Explained Sir. Thankyou
@cindylalthanpuiisena143
@cindylalthanpuiisena143 Жыл бұрын
very informative
@drvinaybaddoley
@drvinaybaddoley Жыл бұрын
Thank you very much. Indeed! Very helpful
@classycannabis
@classycannabis 6 ай бұрын
Thank you
@musekedir1793
@musekedir1793 Ай бұрын
Thanks so much, very informative
@grazryan
@grazryan 4 ай бұрын
Congratulations Professor. For a Very concise lecture!
@stanleykim1924
@stanleykim1924 4 ай бұрын
Thank you!
@gustavonaves6947
@gustavonaves6947 11 ай бұрын
Thanks for the informative video! My father has HCC. God bless you
@stanleykim1924
@stanleykim1924 11 ай бұрын
Wish him well!
@nelsoncaraig3120
@nelsoncaraig3120 10 ай бұрын
Very informative video. Dr. Stanley Kim, may Mother has diagnose hcc, this month only her Dr. Cannot advice of biopsy becouse the age of my mother is 88 years old. But he advice to take Pivka ll, result of Pivka ll of my mother is 29000 is it accurate to detect the cancer cell or not?,,,
@Sameerjan-qx2ks
@Sameerjan-qx2ks 5 ай бұрын
Thanks dr stanleykim. My mother has diabetes since 2002 and using insulin. She is also having blood pressure disease. Her age is 69. She is diagnosed with HCC in sep 2022 with 5cm size in segment II with AFP normal. She is Hepatitis B and C negative. As of sep 2023 HCC size was 8 cm. She underwent TACE in 5 oct 2023. Remained in hospital for 20 days because of high fever, constipation and body ache. IR radiologist says TACE went well. HCC size is 7.2 now. We will again do CT with contrast in FEB 2024. Now she is discharged but from past 1.5 months she is having uncontrolled blood sugar level getting high as much as 450 and low as 80. Her BP is also stabled just 15 days back. But she is having sever constipation issue and also developed piles. How you see this case sir. Your kind words may benefit her. Regards
@abdullaalthaher
@abdullaalthaher 6 ай бұрын
Thank you for the infroamtive lecture. but regarding the introduction slide, did you mean (falciform ligament) intstead of ligament falciparum?
@stanleykim1924
@stanleykim1924 6 ай бұрын
Yes, ligament falciform.
@3putt548
@3putt548 Ай бұрын
I wish my state had “Dying with Dignity” legislation passed.
@stanleykim1924
@stanleykim1924 Жыл бұрын
Addendum: At 15:10, I described the BCLC stage A. I would like to add that any solitary tumor >2 cm belongs to stage A.
@anujsharma87
@anujsharma87 9 ай бұрын
doctor could you please explain about metastatic liver and colon cancer treatment and curre possibility
@stanleykim1924
@stanleykim1924 9 ай бұрын
Some patients with metastatic colorectal cancer can be cured. Please watch my KZfaq lecture about colorectal cancer.
@simplepleasures9650
@simplepleasures9650 3 ай бұрын
Hi sir,for HCC and mouth cancer immunotherapy work's for both? Which drug is used in immune therapy for both t he cancer?
@simplepleasures9650
@simplepleasures9650 3 ай бұрын
Hi sir pembrolizumab immunotherapy works for both mouth and liver cancer?
@tinatj4760
@tinatj4760 9 ай бұрын
Very well-explained video, thank you dr. Stanley! My father has been diagnosed HCC last week, and he got immunotherapy using atezolizumab and bevacizumab, also a radiotherapy session, just for prolong said the oncologist, can't be cured. Is the patient will survive longer if he gets immunotherapy routinely? Are there any possible side effects of immunotherapy and radiotherapy for a 77 years old male patient? thank you in advance
@stanleykim1924
@stanleykim1924 9 ай бұрын
It depends how well he responds to the treatment. If he did, he may be able to live long with continuation of immunotherapy.
@tinatj4760
@tinatj4760 9 ай бұрын
@@stanleykim1924 thank you doc
@viralvideos3.O
@viralvideos3.O Ай бұрын
How ur father now?
@tinatj4760
@tinatj4760 Ай бұрын
My father has received 9 cycles of atezolizumab and bevacizumab and showed good result. In this early month, the CT scan evaluation showed there was a growth size of one nodule and the AFP was also increase to 40 mcg / L (usually AFP is around 20), so he had radiotherapy (1 session) and the immunotherapy agent has been changed to nivolumab single agent.
@tinatj4760
@tinatj4760 Ай бұрын
​@@stanleykim1924May I ask your suggestion for my dad case ? He is 78 years old, so far doesn't suffer from any pain related to his HCC. Thank you
@user-ls7nk9nt2z
@user-ls7nk9nt2z 10 ай бұрын
Doctors could you please explain about stage 4 hepatitis liver cancer ?
@stanleykim1924
@stanleykim1924 10 ай бұрын
It’s very advanced stage of liver cancer. Immunotherapy is the treatment of choice.
@simplepleasures9650
@simplepleasures9650 3 ай бұрын
Hi sir,in HCC what is the use of using sbrt and cyber knife in the view of portal vein tumour thrombosis?the liver lession is about 15 to 18 cm ?
@viralvideos3.O
@viralvideos3.O Ай бұрын
Hai how is ur dad now??
@simplepleasures9650
@simplepleasures9650 Ай бұрын
@@viralvideos3.O hi, he is dng gd..we have started him immunotherapy atezolizumab and bevacizumba..only 1 cycle is completed..dr.said us to do 3 to 4 cycle... hoping for best...
@belenveronica9775
@belenveronica9775 Жыл бұрын
Hello Dr. My sister has Neuroendocrine cancer in the liver Release the hormones carcinoid im looking for any other help please help her please
@stanleykim1924
@stanleykim1924 Жыл бұрын
Please watch my KZfaq lecture: Pancreatic Cancer and neuroendocrine tumor.
@julierambarran460
@julierambarran460 11 ай бұрын
Dear Dr can someone with liver cancer receive treatment and live? Thank you
@stanleykim1924
@stanleykim1924 11 ай бұрын
Yes, but patients with later stages may not do well.
@user-ls7nk9nt2z
@user-ls7nk9nt2z 10 ай бұрын
Is there have any cure for HCC(BCLC stage C )?
@stanleykim1924
@stanleykim1924 10 ай бұрын
Probably not. But some patients live for many years especially with the fibrolamella type.
@user-ls7nk9nt2z
@user-ls7nk9nt2z 10 ай бұрын
Thank you for your answer . Is chemo therapy does work ? HCC (BCLC stage C )
@stanleykim1924
@stanleykim1924 10 ай бұрын
No
@user-ls7nk9nt2z
@user-ls7nk9nt2z 10 ай бұрын
@@stanleykim1924 then which treatment would you like to suggest ? Please
@simplepleasures9650
@simplepleasures9650 4 ай бұрын
Hi dr my dadage is 66 suffering from hepatocellular carcinoma and liver size is enlarged as 18 to 20 cm..nw wht treatment should do...bfr he operated tongue cancer surgery n radiation and chemotherapy n in sep pet scan everything report r normal but last dec wen did pet scan dat tym v cm to knw dat near 2 lymph nodes again hv carcinoma..so nw why we hv to do...
@stanleykim1924
@stanleykim1924 4 ай бұрын
For advanced disease like Stage C by BCLC, systemic therapy is recommended. Please review my lecture.
@simplepleasures9650
@simplepleasures9650 4 ай бұрын
@@stanleykim1924 tqsm dr..🙏
@simplepleasures9650
@simplepleasures9650 4 ай бұрын
@@stanleykim1924 den wht treatment should we give for liver
@simplepleasures9650
@simplepleasures9650 4 ай бұрын
Den what treatment we give fr liver
@stanleykim1924
@stanleykim1924 4 ай бұрын
I described in my lecture. Also discuss with his oncologist.
@buddhika5527
@buddhika5527 7 ай бұрын
Doctor my father has a liver tumor 11cm* 10cm like and multiple malignant dots.. He is 63. He has cirrhosis also non alcoholic. Can we do a transplant im in srilanka....TACE did. Will he live more than 10 yrs without transplant? Doctor what should I do?
@stanleykim1924
@stanleykim1924 7 ай бұрын
Please watch my lecture. The answers of your questions are found there. Translation is not indicated.
@simplepleasures9650
@simplepleasures9650 4 ай бұрын
@buddika5527.. how's your father now?did ur dad faces any problems after TACE..n surgery is done before TACE
@viralvideos3.O
@viralvideos3.O Ай бұрын
How is ur father now??
@cl56611
@cl56611 10 ай бұрын
Management of HCC is complicated. Your lecture is nothing but reiteration of book work, though comprehensive, almost lack of personal concept or recommendation, while some parts are outdated. The parts on PET and Y90 are confusing, if not biased.
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