How Do Nitrates Work? (Nitroglycerin)

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Күн бұрын

How do Nitrates (Nitroglycerin) Work? These direct nitrates are vasodilators that increase cGMP which causes veins to dilate . This causes an increase in oxygen supply to the heart, which reduces angina (chest pain).
There are 3 main drugs in this class: Nitroglycerin (NitroSTAT), Isosorbide Mononitrate & Isosorbide Dinitrate.. They are all vasodilators. These medications are used to treat and prevent angina pectoris.
Time Stamps:
- Intro 00:00
- Breakdown 00:12
- Nitrate Overview 00:22
- Mechanism of Action 02:13
- When to use 05:07
- Dosing & Adjustments 06:09
- Side effects 08:30
- Quick Summary 10:22
- Short Quiz 11:55
- Shout Out 12:30
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4.) D
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Пікірлер: 100

@ronkwarin6917 3 жыл бұрын

I think, Nitroglycerin reduce preload which mean reduce venous return to the heart and reducing working load of the heart, reducing oxygen demand in myocardium. Dilation of artery will effect coronary arteries thus increase oxygen supply to myocardium.

@ismelzavalagatcia601 3 жыл бұрын

En espanol

@MoniBrice 2 жыл бұрын

This is beautifully written. Thank you!

@skabdullatif6594 2 жыл бұрын

Thank you very much for describing in short

@bobcocampo 2 жыл бұрын

Will isosorbide dinitrate be a good supplement to improve nitric oxide?

@anjelsgrandpa Жыл бұрын

@@ismelzavalagatcia601 gg th h yu

@DrugChug 3 жыл бұрын

Thank you so much for the support guys! Glad to see this community growing! More videos are being worked on as we speak! 😁

@BowgFrowg Жыл бұрын

Let's do meetups where we take drugs! Together! As a community 🚰

@sydneyangielli4717 2 жыл бұрын

The best of the best. This should be what every cardiologist should tell their patients to watch as an intro to medications he/she prescribes. Well done!

@rasmanyt 3 жыл бұрын

first time watching...to me u are a godsend online doctor...u speak so clearly, right speed and v clear pronunciation...am feeling so happy stumbling upon u today while checking on GTN

@BK-mg4we 3 жыл бұрын

You explain it so flawlessly!! It’s finally clicking!!!

@sunrunnernge560 3 жыл бұрын

Bloody brilliant video. As are all your others! The best ones on the internet IMHO

@DrugChug 3 жыл бұрын

Thank you Sunrunner! 😊

@jayibakumarra 3 жыл бұрын

This was great! I wish every class was taught like this!

@vanw1504 2 жыл бұрын

You are doing a fantastic job! Thorough and straight to the point! Excellent!

@dollychew4064 3 жыл бұрын

I can only appreciate how much effort you have put into helping educate the community and viewers. Thank you so much!

@DrugChug 3 жыл бұрын

Thank you so much for your support! 😁

@bobcocampo 2 жыл бұрын

@@DrugChug Can Isosorbode be used as a supplement to improve nitric oxide level in the body?

@rethijja3331 2 жыл бұрын

Omg thanks a lot this is the vedio that I've been looking for!! Amazing work 👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼

@rachj1398 2 жыл бұрын

Thank you for making these videos. Very informative and helpful

@goddestroyer3416 3 жыл бұрын

Very good videos! I'm learning so much, thank you so much, keep them coming.

@DrugChug 3 жыл бұрын

Thank you for the support! More videos are planned! Stay tuned

@harrytrev0167 3 жыл бұрын

Congrats on the 10,000 subs. Great videos!

@DrugChug 3 жыл бұрын

Thank you so much for the support!

@mr.medtech731 3 жыл бұрын

Keep making more videos boss. They’re so helpful.

@DrugChug 3 жыл бұрын

Thank you for watching! More videos are being made!

@fluffyrider9467 2 жыл бұрын

Thanks I have a Pt teaching assignment and this helped a lot!

@lynvigna4127 3 жыл бұрын

Thank you so much very helpful!

@peejread2309 3 жыл бұрын

Clear and understandable explanation. Thank you!

@DrugChug 3 жыл бұрын

Thank you for watching! 😁

@rightway1625 2 жыл бұрын

Really appreciate your hard work and thanks for giving us a mindful lectures

@croys8608 Жыл бұрын

Superb quality of information. Thank you. I enjoy pharmacology now!

@raedabuzant7626 Жыл бұрын

Thanks for the great job you did upon this educational video, this was really amazing.

@eck1438 2 жыл бұрын

Nice& detailled to ease the subject...i appreciate it..

@jaclynhernandez7547 10 ай бұрын

Thanks for the great content. You made it so easy to learn (:

@pharmbydas 2 жыл бұрын

my pleasure for your teaching skill thats simple and smart

@ultraplayer2323x3 2 жыл бұрын

Thank you for this lecture!

@NeetuKumari-mx3nk 3 жыл бұрын

Appreciated 🙌🙌 thank yu so muchh .. This helped me alottt to understand .

@DrugChug 3 жыл бұрын

You're welcome 😊

@nanaperry1066 3 жыл бұрын

Thanks so much, understanding you is so easy.

@DrugChug 3 жыл бұрын

Thank so you much for watching, more videos are planned!😄

@nyawirawaithaka4993 3 жыл бұрын

Thank you!

@iraqi3612 2 жыл бұрын

that was too useful♥thank you Doctor

@sravanip2404 11 ай бұрын

OMG it was a great explanation ❤

@pengseansem2505 9 ай бұрын

Great presentation, thank you very much.

@nurseraidarider7140 4 ай бұрын

Thanks a lot, very clear explanation 😊

@sufiyashah4694 2 жыл бұрын

amazing bro omg thank u

@imadyousufzai2998 2 ай бұрын

Thank you sooo much ❤❤😊

@CynthiaMartinez-qp8gm 6 ай бұрын

Do you have more videos? There’re super helpful.

@lahirudissanayaka-mk8sq Жыл бұрын

superb...❤❤❤

@umm_kulsum1 7 ай бұрын

Thank u so much

@chamarimendis5596 Жыл бұрын

Superb. I really helpful.

@drx.monishansari6188 7 ай бұрын

Thank you so much sir this is very helpful to me❤

@spiritclouddesouza3014 2 жыл бұрын

Thank you so much, just started Iso....today, needed to hear this.

@Selfbelive636 5 ай бұрын

Thanks❤

@MauiXoXo Жыл бұрын

I appreciate the video. I am a visual learner. New subscriber here.

@sathghuru 9 ай бұрын

Very Good Explanation Thanks from India

@bobcocampo 2 жыл бұрын

Can you take isosotbide if you are prediabetic as prevention for heart disease and kidney disease?

@winghosamLeung-ff3bu 10 ай бұрын

What is your comment of Nitriglycerine cream use for improvement of ED ??

@bobcocampo 2 жыл бұрын

Is there a contraindication of niacin with isosorbide dinitrates?

@bobcocampo Жыл бұрын

How about if you only take 5mg Isordil for prevention? Can you take it every 12hrs?

@rhodamaliwa770 Жыл бұрын

Thank you so much for your simplified explanations 🙏🙏🙏🙏 Am kindly asking if you can make videos on GIT pharmacology drugs 🙏🙏🙏🙏🙏🙏🙏🙏🙏

@azadysarchn1659 4 ай бұрын

Thank for your explanation of all the drugs I found Please if you have any explanation of the role of garlic metabolism and as a drug if we counted like a drug not like a food... it's pharmacology

@ahmedthamir9531 Жыл бұрын

what is the difference if any between mono and dinitrate?

@CraigMullins1 2 жыл бұрын

Would it be unsafe for anyone to take? Any precautions? I have been having chest pain & headaches ever since covid vaccine and wanted to see if it helps.

@gottabepablo 2 жыл бұрын

If you have a history of low blood pressure or take ED medication then it’s not recommended to take Nitro. Aside from the fact that it’s also a medication that must be prescribed. Also a side effect are headaches, it really won’t make those go away. I’d talk to your or a doctor before obtaining and taking it.

@teamgo9980 2 жыл бұрын

Do I need to lock up my nitroglycerin in a cabinet. I’ve been carrying it in my left pocket since I had my heart attack at the age of 36 and I am healthy as a horse when I had my heart attack it was just runs in my family. I have a question and I’m just curious but if you have to take more than Three doses five minutes apart and it hurt you or kill you?

@gottabepablo 2 жыл бұрын

It can potentially lead to hypotension, which can result in a lack of sufficient oxygen delivered to important parts of the body like your brain. Which is no bueno :/

@bobcocampo Жыл бұрын

Any research on the effect of NO with CKD?

@thehigherevolutionary 3 жыл бұрын

Dang, I missed the premiere!!!

@DrugChug 3 жыл бұрын

No you didn't! Haha, sorry I was testing out how to publish the premiere and accidentally just published it 😅

@evelynorta232 3 жыл бұрын

I have a question, what if you're 18 year old girl with Scleroderma taking Sildenafil for high pulmonary arterial hypertension and also taking nitro bid as well. Is that bad?

@ilhamjirde2954 2 жыл бұрын

Sildenafil and nitrates are both vasodilators, thus their combination can lead to severe hypotension which is bad

@tski3458 2 жыл бұрын

Do the headaches ever go away?

@Jada452 2 жыл бұрын

What will happen if you stop taking your inder?... I for got for a few days or a week idk tbh... but OMG! It felt like I was having a heart attack! Worst trust brain I've ever felt in my life!! and I was Also extremely stressed out stone am lol but the pain is not as bad now no last as long as be for

@faithosawe338 2 жыл бұрын

Love this teaching like it was very calm so every word was just penetrating . Lovely

@princeabdo5434 3 жыл бұрын

Keep making videos u will reach a million subs when people find ur channel

@DrugChug 3 жыл бұрын

Wow! Thank you for the continued support!

@sutenly1 5 ай бұрын

Can reduce plague?

@mohmedyzed8920 3 ай бұрын

thnx 4m egypt

@bobcocampo Жыл бұрын

If you don't have angina pectoris can you use Nitroglycerine in low dose as supplement?

@teknofreak2387 Жыл бұрын

I would not, but i also thought about this🤔it expands the blood vessels so it could be used for lifting (like many bodybuilders use viagra to get more pump), but it also would be interesting how it affects sex. Another angina pectoris medication (Amylnitrite) is widely used as „poppers“ cause sex on it feels awesome. Only downside is that it only lasts about one minute, and that you habe to inhale it. Would be interesting if nitroglycerin has similar effects, at least the side effects named in the Video Sound similar😂

@bobcocampo Жыл бұрын

@@teknofreak2387 Do you know of any research? Will it help CKD?

@teknofreak2387 Жыл бұрын

@@bobcocampo i dont know i didnt study Pharmazeutics at an university yet im just a pharmazeutic tecnician😂dont know how you call it in USA. I didnt find any study and dont think they will do ones on th „recreational“ use of this medicine. But self experiments wouldnt be that hard and maybe also fun😂

@DrRK_HEALTH Жыл бұрын

👍

@ismaielhassanbara843 Ай бұрын

❤❤❤😊😊😊

@kimienick6721 2 жыл бұрын

Its give good return result, but the side effect headache mix with hypertension😑😑😑 can made you struggle for 2 night

@naveena3712 3 жыл бұрын

Where are the answers for ur questions

@jonathanvasquez-mv9ic 10 ай бұрын

Epipen

@rottiesdad Жыл бұрын

Back in the 80s and 90s I had to walk to my library when I was curious and wanted to learn. Now it's at the touch of a button. Almost all knowledge. So my question is why do I see morons every fucking day EVERYWHERE!?

@kohlrabenschwanz 4 ай бұрын

it "literately" means chest tightness or constriction.... not pain. tf

@Selfbelive636 5 ай бұрын

b .c .d. d

@karinahastika7362 Жыл бұрын

came here after watching how Johan Liebert killed 1 director and the other 2 doctor in monster anime 😅

@frankargenti Жыл бұрын

ja sniffing mononitrate is not the best experience

@kimienick6721 Жыл бұрын

I CANNOT use Isordil and another unstable angina medicine.. I can use nitroglycerin only 😅 I also have experience use nitroglycerin two pieces tablet in same time and it only used for STRESS TESS or MSCT SCAN treatment... Only me can sweet dreams inside MRI machine 🤣 the rest need monitoring after check up...☺️ But after 3 days I admitted to hospital due WALKING alot after colouring injection into blood.. no option because I ride Commuters 🚈 😅