Yet another example of a complex and intricate biological system mediated by numerous proteins and enzymes, themselves complex machines , choreographed in what seems to be an irreducible pathway essential for the viability of the cell. The oft mentioned evolutionary conservation of this mechanism begs the question of what possible alternative could be imagined to function in any supposed intermediate state.

you replace the gene in the yeast's genome with a version that codes for the protein plus the signal seuqence.

The man is a Nobel Prize winner. Tell me Vlog, Thoughtless, Dying and Hopeless one, what accolades have you received for your contributions to body of knowledge in biological sciences?

According to indian saying where iam from in rig veda composed 13000 years ago there is saying dnt argue with a fool its a waste of time and never throw stone in mud your clothes will become dirty ken leave the fool in their ignorance

Hahahaah..... I hope so...

I think it’s as a joke lmao. He presented the same image in his Nobel prize presentation (at least the one found on nobelprize.org has that image too!).

Living in Berkeley the past ten years I'd say it's real

This is an iBiology lecture it has nothing to do with Berkley. Your semi-literate musings are not amusing; trolls belong under bridges; best you find yourself one to crawl under. As a sad sick old woman you should hold your tongue, lest you bring upon yourself the wrath of Ken.

i like u ken grt comment lolz