A song Clapton wrote about George Harrison's wife, Patti Boyd, whom Clapton desired, later married (and still later, divorced).

One of, if not the most, recognizable opening riffs in rock.

He’s a recovering drug addict he’s been sober for about 35 years

Now you must check "Layla" as originally recorded by Derek and the Dominoes ( Eric Clapton and Duane Allman). This song,and the entire album has been a soundtrack in my life since high school, when it was released. That song is more phenomenal with Duane Allman's guitar.

The original version of this song will never be topped

This is probably the best live version of Layla, as far as being true to the album. I'll tell you what though, imho nothing can match the album version for sheer power and raw emotion. You've got Eric Clapton on vocals and guitar, Bobby Whitlock singing background vocals and Duane Allman on lead and slide guitar. The chemistry of that mix resulted in a spontaneous guitar dialogue between Eric and Duane. It was a once in a lifetime musical event, fortunately recorded for posterity. (A tip of the hat to Tom Dowd, the genius recording engineer who mixed Layla).

"Why Does Love Have to be So Sad".. Another great Clapton tune...

brother this is the deepest rabbit hole , from the early rock to the 80's pop to the 90-current blues hes a legend and my favorite

Duane Allman played slide guitar on the original ✌️

Every Layla I've ever met was named after this song

I agree with the other comments about the album version of Layla, Duane Allman on that slide guitar is something that just needs to be heard, it touches your soul.

George and Eric used to jokingly refer to each other as “husbands in law”

You need to hear the original Derek & The Dominos album track, and then Clapton's 1992 MTV unplugged version...both different styles, and both legendary.

Clapton's "Bellbottom Blues" is my 2nd favorite, right after this one.

I’ve read that Eric Clapton was crying during the recording of this song.

I'm tempted to say that Eric Clapton is the model for amplified blues guitarists since the 1960s. Some play faster, some play flashier, but he is the building block for much of it.

He's been inducted into the Rock & Roll Hall of Fame 3 times for The Yardbirds, Cream, and as a Solo artist. I believe the only artist with 3 inductions.

His live cover of Bob Marley's "I shot the Sheriff" is a classic!!

Motherless Children from 461 Ocean Blvd. The original Layla, with Duane Allman, would prob. get blocked but you can always put it at that other place. Duanes guitar really must be heard.

"Everybody working together and making everybody better" Always a warm & wise reaction. Thank you!

In the studio version, the pretty part has Duane Allman playing a slide guitar solo over it.

After Midnight, Let It Rain, Lay Down Sally, Bell Bottom Blues, Running On Faith, I Shot the Sheriff, so many greats

I was at this show. Amazing concert. Bob Dylan, Sheryl Crow and Mary J Blige were the special guests.

Legend! Absolutely no other word can describe Clapton! Slow hand you are most definitely the man!

I was named after this song! I still unashamedly have it on my playlist. :)

"Lay Down Sally" Jamel, you won't regret it

Clapton is one of the most enduring figures of modern rock. Before going out on his own, he was part of John Mayall's Bluesbreakers, Cream, and Blind Faith in the Sixties -- all hugely influential.

There's an AMAZING backstory to this song. The song was inspired by a love story that originated in 7th-century Arabia and later formed the basis of The Story of Layla and Majnun by the 12th-century Persian poet Nizami Ganjavi, a copy of which Ian Dallas had given to Clapton. The book moved Clapton profoundly, because it was the tale of a young man who fell hopelessly in love with a beautiful young girl, went crazy and so could not marry her. The song was further inspired by Clapton's then-unrequited love for Pattie Boyd, the wife of his friend and fellow musician George Harrison of the Beatles. Clapton and Boyd would eventually marry. Listen to the original, and listen to the beautiful piano solo at the end. Absolutely amazing.

I am blessed to have seen Eric Clapton in 1990 live in concert, Standing in the first row. As a young guy whose dream was to play guitar like Clapton, this gig was mindblowing....and yes he played Layla as well 😄

The "Unplugged" version is very different but still very good.

And THAT, ladies and gentlemen, is why they call him Slowhand.

My favorite Eric Clapton song is a lesser known piece called "The Core". Features beautiful backing vocals from Marcy Levy, aka Marcy Detroit.

I’m so glad they performed the whole song, the last part is the best part

I like it when I haven't heard an Eric Clapton song in a while and someone pulls up a live version.

Seen Clapton rock out live to this many times. Awesome every time.(Usually when he had "Jesus" hair.)

“She’s Waiting” and “Forever Man” are excellent too!

OK man you might as well do Clapton "Cocaine" ..live version!

Hi Jamel, this song was written for George Harrisons then wife, Pattie Boyd. He also wrote Wonderful tonight for her. She left George for Clapton. Greetings from Ireland. ☘☘☘ love this.

The 1970 album is operatic in intensity, an emotional rollercoaster.

Clapton will always be my favorite guitarist. His talent is unsurpassed.

Also the live cover of While My Guitar Gently Weeps with Prince, Tom Petty, Steve Winwood, Jeff Lynn etc. Prince kills it!

It's an all star line-up for this one. The great Steve Gadd on drums, Nathan East on bass, David Sanborn on sax.

I didn't know I was such a huge fan until I saw him in concert. I literally knew every song. Great memories!

. My #1......Eric is simply rock royalty... Nathan East on bass, David Sanborn on sax. MSG in NY.....Iconic song

Hey Jamel! Love me some Eric Clapton-his nickname is: "Slow Hand."

He’s so damn smooth that he makes it look effortless to play like that. Let me tell you it ain’t.

The "slow hand" at his best,one of the greatest guitars the good Lord put on earth,mind blowing,teeth rattling,pure Clapton.......get some!

Watch a documentary called "Tom Dowd and the language of music", Tom Dowd was a genius recording engineer and producer for Atlantic Records. In the roc doc he relays stories about the epic recording sessions he was evolved with. He speaks of the "Layla" sessions and how Clapton and Duane Allman would play off of each other to create that soul scorching solo. Tom Dowd is sitting at a mixing board(which he invented by the way) and he's playing with the mix, at one point he has it all stripped down except the two guitars, and he looks at the camera and say's, with a child-like fascination and exuberance,"Do ya hear those notes? Those notes aren't even on the instrument, they are coming from somewhere else.". It's a fascinating documentary about a fascinating man, it's unbelievable the contributions this man made to the industry and we have the U.S. Government to thank, watch the movie , you'll see.

One of the greatest guitarists ever. Love Clapton

Now check out The MTV Unplugged version. It's like an entirely different song.

One of the most classic riffs in rock and roll history!

LAYLA- DEREK AND THE DOMINOES!!! THE ORIG VERSION FROM 1970

Another great reaction, Jamel! This man - Mr. Eric Clapton - is one of those guys that can do it ALL! He's a great writer, singer, as well as an amazing guitar player. I know you've already posted a couple of other EC reactions, but you might as well just go on ahead and jump down the EC rabbit hole as well, my friend :) You won't regret it!! As always, thank you for what you do! Stay safe!!

Thanks Jamel. Great song that you have now met : ) Keep up the great work. Keep well and safe, Brother.

Accoustic version (unplugged) adds still another twist to this amazing classic . Don't miss out , my brotha .

you just witnessed one of the greatest guitarists ever✌️

You just witnessed one of the great guitarists of all time.

Check out his unplugged version of this song. It is my favorite!

Great to see the musicians play the song live. You really get a whole different vibe. Thanks for bringing the music!

The reaction of the bass player is priceless!

This right here might be the greatest guitar riff of all time!

Let it rain, from the same album, such an incredible song.

One of the most beautiful instrumentals ever written. Peace and Love, Brother Jamel.

He is amazing live, it feels like he really loves what he is doing. I went to see him live in ´98 a couple of weeks before I turned 17. He played Layla and it was kick ass! (and Tears in Heaven where i cried my eyes out)

Can't hear the second part without thinking of Goodfellas!! lol

Can you imagine a musical interlude in a song today, oh that's right nobody plays instruments today, you scratch vinyl or hit a computer button...

this instrumental always reminds me of the movie "GoodFellas". probably one of my favorite instrumentals ever.

One of the eternally great songs ... people will be listening to this 500 years from now

Bass Player: Nathan East of Fourplay Sax: David Sanborn

The transition to the pretty part is quicker on the record. He's teasing the crowd, making them wait for it.

This song just knocked the wind out of me.thisman is something else with that 🎸 and that voice.💞💞 thanks Jamal.

Check out Clapton's modern blues-style version of this song. It's amazing. Also, his song "Wonderful Tonight" is one of the most romantic songs ever made.

LOVE that you finally did this one...but the audio versions/studio versions are really superior for the full appreciation without all the distractions and glitches of a life performance. Oh, this song is SO LUSH in it's original version.

This isn’t in my personal top 10, but if I was filling a time capsule to explain Rock n Roll, this would be one of the songs entombed.

Eric Clapton, along with some select others, is one of those artists who float around the ether head and shoulders of the rest. Oh, and he's a world renowned master guitarist Mr Slow Hand!

We have seen eric 5 times. My husband saw him 2 other times before we married. He truly makes you feel like you're in something really surreal. Nathan East was on bass when we saw him. And the last time he did a concert called Nothing but the blues. My mom was around 70 then and she went and loved it. Great seats that evening. We've seen all rock Layla and all acoustic. Her favorite song was Alberta,Alberta

I wish I could hear Layla again for the first time. Still gives me chills. In fact, your a lucky cat to get to hear the entire catalog of music that is on your channel. Bezos can't even buy that.

My mom named me after him because I was kickin' in the womb while she was at a Derrick and the Dominos(the band he was in when he did this song) concert.

I have the opening riff as one of the ringtones on my phone. One of my all time favorites. Well done, Jamel. ✌️

These are the songs I was privileged to listen to growing up. I love them now even more than back then. The talent, beauty and hear felt reaction from their souls was clearly evident.

Add Clapton's "After Midnight" and "Cocaine" to the list. These are actually covers of J.J. Cale, so add Cale's "Travelin Light". Cale has an incredible and unique sound. Do Cale's After Midnight along with Clapton's version for southern and British variants.

Tears in Heaven has to be one of the saddest songs of all time

you need to hear the unplugged version of this.. Holy cow it's amazing!!!

Can't wait to see your face! The song Bell Bottom Blues is incredible too!!! I saw Clapton live in 1978. It was his Slow Hand Tour. Mind blowing 🤯

This is an awesome song Jamel!! 🙌✊🔥

I've been waiting for you to finally do Layla but you did the wrong version. The original version by Derek and the Dominos featured Duane Allman on lead and slide guitars. Duane MADE this song as he composed the signature riff and turned it from a ballad to a rock song. This was one of the greatest clasic rock songs of all time. Please🙏 do the original studio version and also check out the back story of how Duane and Eric came together

Lucky enough to have seen him live in the early 90's in Dallas Texas. One of the best concerts for sure.

"Bell-Bottom Blues" and "Promises' are absolute MUSTS!

One of the best guitar players ever. Someone asked him who he thought the best guitar player was, he said Prince. Great compliment.

You need to hear the original, with Duane Allman on the slide guitar at the end.

Duane Allman’s guitar work on the original is magic. The main riff was his, and Clapton played it, and Duane played slide. The screeching guitar is Duane and it’s amazing.

Such talent! And he looked like he was having fun. Wonderful!

This live version is good but to experience the real song you need to listen to the studio version. Look for "Derek and the Dominos" After that you can check out the unplugged

This song is on the soundtrack at the end of the movie "Goodfellas."

One of the most recognizable opening riffs. Right up with Smoke on the water. Clapton, Jimi Hendrix, Jimmy Page, Pete Townsend. Can't go wrong with a guitar by any of them. Thank you for sharing with us.

I saw him at Legion Field in Birmingham in 1974, 'I shot the Sheriff' was his big hit at that time. Great concert.

I love both the original version and his unplugged version.

You have to listen to the original off the album. Duane Allman is outrageously great on slide guitar,it blow this version away!!! Keep rockin'

Perfect example of why they call him Slowhand. He doesn’t do tricks, he just combines every note into perfect phrases. Masterful!!

Check out the acoustic version.....it holds up even without all the bells and whistles. He wrote it about his friend George Harrison's wife. She responded that everyone would know how he feels...he made it, and later George attended his wedding to this woman!! True brotherhood man! 💘