Longevity Influencers Are Killing You

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Dr Brad Stanfield

Dr Brad Stanfield

10 ай бұрын

5 popular longevity strategies are trending everywhere, but they likely shorten your lifespan instead of improving your health.
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Here are the links to the research papers referenced in the video:
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.uptodate.com/contents/pra...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
pubmed.ncbi.nlm.nih.gov/18728...
pubmed.ncbi.nlm.nih.gov/25041...
www.ncbi.nlm.nih.gov/pmc/arti...
pubmed.ncbi.nlm.nih.gov/25041...
diabetesjournals.org/care/art...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.cochrane.org/CD013496/VAS...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
pubmed.ncbi.nlm.nih.gov/31486...
pubmed.ncbi.nlm.nih.gov/31869...
pubmed.ncbi.nlm.nih.gov/15684413
www.ncbi.nlm.nih.gov/pmc/arti...
www.fiercebiotech.com/r-d/upd...
www.ncbi.nlm.nih.gov/pmc/arti...
www.uptodate.com/contents/lip...
pubmed.ncbi.nlm.nih.gov/32755...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
pubmed.ncbi.nlm.nih.gov/27754...
ods.od.nih.gov/factsheets/Vit...
www.ncbi.nlm.nih.gov/pmc/arti...
pubmed.ncbi.nlm.nih.gov/15557412
www.cochranelibrary.com/cdsr/...
ods.od.nih.gov/factsheets/Exe...
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#Longevity #Health
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Пікірлер: 2 100
@DrBradStanfield
@DrBradStanfield 10 ай бұрын
Alarming consequences for each of these 5 'longevity' strategies, let alone if they are combined together... 💪 Roadmap - How to look young and feel strong: drstanfield.com/pages/roadmap 💪 Join Patreon for early access to my videos & Discord chat: www.patreon.com/bradstanfieldmd
@arallskiant9923
@arallskiant9923 10 ай бұрын
low protein diet do not affect much muscle. what affect muscle is inactivity not whether one eat 10% or 20% (1.7g per kg) of kcal from proteins. But if one avoid animal proteins thing should be okay with western level of proteins. Animal proteins cause ectopic fat in the muscle (like old age, there is a loss of muscle quality) not even talking about the rest of the animal kcal (pollutant, zoonoses, there fats etc)... okinawans and many other centenarian population live the longuest with very low protein diet. your evidence of harm in resveratrol is for mice. the cochrane quote you shown just after contradict you claim about harm. idk about resveratrol and its metabolite but things would not be surprising on this side maybe. Though I agree supplement of it is useless.
@lkeane3591
@lkeane3591 10 ай бұрын
Do you have any papers to show the mechanism behind, or just to confirm that animal proteins cause ectopic fat? Also, your input on Okinawa is wrong. Apart from the interwar period, where island bombardment killed the majority of livestock, the Okinawan Diet has always been extremely High in pork. Before the war, and After the war, pork remains one of their most consumed Foodstuffs.
@Jim-et3ef
@Jim-et3ef 10 ай бұрын
Thank you doctor. I will stop intermittent fasting. Frankly, no great sacrifice.
@iranjackheelson
@iranjackheelson 10 ай бұрын
Doc, just can't help but seeing this contradiction here: 9:45 "low-dose stress signal to our cells that they need to become more efficient... this theory is UTTERLY REDICULOUS !!!!" 😡😡😡😡😡😡😡😡 11:20 "so when we exercise we stress our body and we release all sorts of oxidants so that stress from exercise is a good thing" 👍🏾👍🏾👍🏾👍🏾👍🏾👍🏾👍🏾👍🏾👍🏾
@jedwards1792
@jedwards1792 10 ай бұрын
five longevity fads to avoid 1) low protein diet / rapamycin 2) metformin use by non diabetics 3) intermittent fasting 4) resveratrol 5) antioxidant supplements like high doses of vitamins C and E
@marstedt
@marstedt 10 ай бұрын
0:11 - 1. Low Protein Diet 3:18 - 2. Metformin 5:32 - 3. Intermittent Fasting 8:17 - 4. Resveratrol 10:25 - 5. Antioxidants
@frostfree7
@frostfree7 10 ай бұрын
Thanks ❤
@gtrgtr8354
@gtrgtr8354 10 ай бұрын
Blue zones have low protein diet..
@volos_olympus
@volos_olympus 10 ай бұрын
@JohnnytNaturalThe clinical guidelines show the downsides of IF. Just because it works for you doesn’t mean it will work for others. There are centarians out there who smoke, does that mean cigarettes are healthy?
@volos_olympus
@volos_olympus 10 ай бұрын
@JohnnytNatural Source on African natives skipping breakfast?
@blaze1148
@blaze1148 10 ай бұрын
@JohnnytNatural Yup - I think he is totally wrong on intermittent fasting.
@markusantonious8192
@markusantonious8192 10 ай бұрын
I've done intermittent fasting for over a decade....usually 18/6....and my muscle mass is perfectly fine.
@EhurtAfy
@EhurtAfy 10 ай бұрын
That's great you found something that works for you! You'd probably look unreal if you optimized protein intake. Muscle protein synthesis lasts for about five hours after ingesting protein. With intermittent fasting there is a large window of time where very little muscle protein synthesis is occurring and muscle protein breakdown may be occurring. My only caution is protein needs may increase with aging to prevent sarcopenia/muscle loss; you might find you need more protein to maintain muscle mass as you age
@ilia2178
@ilia2178 10 ай бұрын
I'm very confused by this as well. Everyone else says that IF is amazing and has a variety of health benefits. Lots of people do it with great results. It works for me too and I build muscles while on IF.
@ryankittle3431
@ryankittle3431 10 ай бұрын
Fasting is fine, if the fast is primarily in the evening and not the morning. Reason being, the body heals and functions better when it is not digesting food right before bed, or while sleeping.
@manmoth4
@manmoth4 10 ай бұрын
What's fine could be good. There are many factors at play, and no one said IF is a singularly crucial one
@DrBradStanfield
@DrBradStanfield 10 ай бұрын
Your muscle mass would likely be significantly better had you eaten your protein meals as per the guidelines from the International Society of Sports Nutrition
@duskrider1724
@duskrider1724 10 ай бұрын
I found short term intermittent fasting (couple days a week over about 6 weeks) very helpful for getting my sugar cravings under control and it even reduced my desire to consume alcohol.
@muzzletov
@muzzletov 6 ай бұрын
pro tip: you could just eat a salad (fiber-rich snacks) prior to consuming sweets, as it slows the absorbtion rate of glucose, thereby reducing impact on blood glucose levels and spikes in general.
@JBSbass
@JBSbass 6 ай бұрын
@@muzzletov hardly smart, adding mostly undigestible plant cellulose to any diet to reduce the impact of the sugar you want to ingest is not intuitive. Its dumb.
@DruidzTV
@DruidzTV 6 ай бұрын
@@muzzletov pro tip: AVOID GLUCOSE & SWEETS
@shapursasan9019
@shapursasan9019 6 ай бұрын
All you need to do to satisfy your 'sugar craving' is with healthy sugars--like coconut sugar, date sugar, and raw honey. That's all you need to do.
@duskrider1724
@duskrider1724 6 ай бұрын
@@shapursasan9019 Sugar is sugar
@9xqspx6
@9xqspx6 10 ай бұрын
Gotta say it's pretty saddening and even frustrating when people whom I'm generally trusting and looking up to within the same field of work (in this instance: medicine) are so strongly disagreeing with with one another and even hating on each other...
@DrBradStanfield
@DrBradStanfield 9 ай бұрын
There’s a lot of agreement within the medical field about how to prevent diseases. There are fantastic preventative care guidelines. People who go against those guidelines can be incredibly dangerous…
@Mudpuppyjunior
@Mudpuppyjunior 8 ай бұрын
The history of science has always been there's a lot of agreement about things that turn out to be completely wrong.
@Atheria444
@Atheria444 8 ай бұрын
Trust no one...ever. Listen to your higher self.
@9xqspx6
@9xqspx6 8 ай бұрын
@@Atheria444 Oh I'm very skeptical, don't you worry! :) But even my higher self didn't go to medical school, nor did it study biology, nor does it have time to read through research papers etc. :)
@mattb2906
@mattb2906 6 ай бұрын
Sticking strictly to guidelines can hinder progress and keep society following old, outdated, no longer relevant recommendations (such as eat a massive amount of grains every day). @@DrBradStanfield It also encourages doctor's to push outdated guidelines in order to avoid possible litigation. It's a fine line to walk for sure.
@TwoStackedCRTTubes
@TwoStackedCRTTubes 10 ай бұрын
I been doing intermittent fasting for almost ten years now, it does wonders for my immune system and I never got sick again in the winter, as I always used to, and my bloodwork results are always great. And by "fasting" I mean I just eat when I'm hungry because I feel NEGATIVE hunger levels in the morning (just like other people in the comments) and after the evening, so I'm highly skeptical of the idea that you need to force feed yourself all day in order to achieve some "ideal" protein intake and absorption, as I hear nothing but positive histories from people who adopt some kind of regular fasting.
@CaptnYestrday
@CaptnYestrday 10 ай бұрын
Agree 100%. Myself and my family concur. Life-changing in that it gave us our lives back after years of poor diet and unsuccessful yo-yo diets
@saulocerqueiradealmeida9700
@saulocerqueiradealmeida9700 10 ай бұрын
IF gave me the same IM system benefits you just described.
@lexolus1308
@lexolus1308 10 ай бұрын
Breakfast is the most important meal of the day, early vitamins and proteins will make you feel way better all day, thats a fact, people are not hungry because their meal schedule is bad and they eat too late at night or eat 2000 calories in a single meal, the point of eating every 4-5h is to keep high levels of vitamins, nutrients etc the hole day
@Simon-talks
@Simon-talks 10 ай бұрын
Same here with my IF results. I built more muscle than anyone I personally know doing it and I realized early on that "breakfast" isn't the most important meal of the day...that's all made up hype.
@vdfadfa
@vdfadfa 10 ай бұрын
Thanks for speaking up! I've been doing low carb diet & intermittent fasting for 10 yrs, never felt or looked better! I'm constantly told how young I look. Results don't lie
@moc5541
@moc5541 10 ай бұрын
About just being able to possibly maintain muscle strength in old age... I can pridefully and truthfully tell you that after starting resistance training at about 75 years of age I have quite substantially increased muscle mass and strength. It's evident in the number of push ups and chin ups that I can do and it's also evident in the mirror--- "lats" sticking out under my arms, biceps, etc. And I got there by using what Dr. Stanfield has already discussed, which is a very high number of reps nearly to failure. Look up "negative pull-ups" sometime if you want lats.
@DrBradStanfield
@DrBradStanfield 10 ай бұрын
Legend!
@manmoth4
@manmoth4 10 ай бұрын
The newer you are, the more potential for growth, so an untrained person can likely gain strength at any age. But retaining muscle is easier than gaining it, so it's still best to build a base while young then work to retain it if possible
@Carnivorous-Vegan
@Carnivorous-Vegan 10 ай бұрын
Wish I could say the same at 62. I _have_ gained strength/endurance, but the actual mass increase is barely noticeable, even after 2-yrs.. Genetics definitely plays a role, because I was much like this even in my youth.. The main thing for me, is letting improvement guide me.. If I stop improving, that's when start questioning things like over-doing it, rest, and nutrition.
@manmoth4
@manmoth4 10 ай бұрын
@@Carnivorous-Vegan Try a 7-10 day training break every few months, studies find markers of anabolism in muscle plummet after consistent training, while a 10 day break re-sensitises the process, letting you gain linearly again. Also, you can try different things, like higher intensity, lower volume. I only lift every other day, 4 exercises for 3 working sets, but I take each one to absolute failure. Works for me.
@bogse
@bogse 10 ай бұрын
Do you do this naturally? You are about the age of my parents and I would like to know if you can get results in mirror without TRT or any other muscle growth enhancing drug.
@oldboy41
@oldboy41 10 ай бұрын
On days where I DON'T do IF, my mental acuity is lower and I generally feel more lethargic. When I break my fast I always load up on protein so no problem there. I am lighter than I've been in years because of IF and no regrets.
@Harry-uq9qd
@Harry-uq9qd 3 ай бұрын
It depends how you’re eating. If you’re eating with lots of protein, fiber, and not overloading on carbs, and not stuffing yourself, not constantly eating between meals… then meals won’t make you lose focus nearly as much.
@johnwilliam6092
@johnwilliam6092 10 ай бұрын
IF isn't killing me. In fact, I feel great. I fast until 4pm, then eat. Ill fast again until 10pm (Due to work commitments). This method massively works for me. No mid-afternoon tiredness, no fatigue. However, ill never work out in a fasted state.
@TheFalzox
@TheFalzox 10 ай бұрын
Any science that has guided you on this? My eating window is from 4pm-10pm as well.
@user-yl7kl7sl1g
@user-yl7kl7sl1g 10 ай бұрын
The video producer didn't read the studies he posted. @6:50 "There is no Added benefit to intermittent fasting beyond calorie restriction". Yet the meta analysis he posted said "We are not confident in our results" and "We didn't find any data on mortality" admitting that the study is completely useless as a datapoint on the longevity effect of fasting. Fasting extends the life span in every species we've tested it in (It's not only mice). Yes, there's ways to correctly fast to get maximum benefits but it's ignorant to say fasting has no benefits. There's so many logical fallacies in these videos, like mixing causation and correlation, drawing conclusions from minimal data points with ignorance of causal mechanisms. Stanfield is aging horrible because he doesn't understand how testosterone works in the body, as are many of these influencers that spend more time presenting than reading and digesting. Recommendation for any one reading this, turn off youtube, start reading, learn statistics, math, logical fallacies, and biology.
@timburnham1214
@timburnham1214 10 ай бұрын
@@user-yl7kl7sl1g I've been eating one meal a day for 15 years. Usually a high protein meal. I also do weight training. I am also Type 1 diabetic. I have my blood work scrutinised by the head of the Royal Melbourne Hospital who is regarded as one of the leading Endocrinologists in Australia. He says I have the blood chemistry of a 25 year old. I am almost 50! While I agree with his other points, I strongly disagree with this guys idea of eating protein every 4 hours. Intermittent fasting is fantastic if you still eat enough protein and lift weights to maintain muscle mass and bone density. This guy will be dead 20 years before me.
@Tom_Mroz
@Tom_Mroz 10 ай бұрын
Same.
@stfnphil
@stfnphil 10 ай бұрын
@@user-yl7kl7sl1g Yep, he is the 'debunking' influencer now. Dr. NO!
@luizfigobr
@luizfigobr 10 ай бұрын
I will have to disagree on the intermittent fasting. It has done wonders for me. My lean muscle mass actually improved in size and quality. Beeing an athlete all my life, so i can tell because i am very self-aware of my body.
@louisralph6206
@louisralph6206 10 ай бұрын
How do you know it improved in size? You probably just got leaner..
@michaelavestro3422
@michaelavestro3422 10 ай бұрын
Did you confirm this with a Dexascan? Or is this just based on how you "feel" and "look"?
@neilgunns8391
@neilgunns8391 10 ай бұрын
Speaking as someone who’s weight lifted his whole life, “we” (people who know their body well) can absolutely tell when something is working.
@ritsukohairsalon
@ritsukohairsalon 10 ай бұрын
so much hatred for this comment.
@Aaayyyeeee214
@Aaayyyeeee214 10 ай бұрын
Gym rat spotted. Opinion accepted. On a more serious note, besides autophagy, intermittent fasting also temporarily increases hgh levels. Also idk about how longevity folk go about intermittent fasting, but fitness people usually try to hit their daily protein intake within the 8 hour eating window. Keep in mind, your sleep time is actually counted as fasting time as well. We're not meat heads who just go about things through pure intuition.
@nikolai71
@nikolai71 10 ай бұрын
i do intermittent fasting 16-18 hr almost 6 years all my allergy symptom's gone , asthma gone im 53 and im in prefect shape in my life
@lexolus1308
@lexolus1308 10 ай бұрын
Very dangerous, you deplete of vitamines, nutrients for very long periods of time, lowers your defenses, I hope you atleast track your vitamins etc, if you have any deficency you can make it worse and get health problems, you might be doing better because you do regular cardio/exercise per week and not the diet, you can almost cure asthma by regular cardio, hydration, etc, its just more effort to train the lungs, i dont really know about allergies tho but people tend to lose them and get them thuought life and exposure to it depending on the allergy, idk if you can cure nut allergy by eating nuts or something, but ive had cat allergy and I brute force it out of my body couse cats are cute asf and i think it mostly went away
@draconisdragonheart4248
@draconisdragonheart4248 10 ай бұрын
You might want to find out what food sensitivities you have.
@Simon-talks
@Simon-talks 10 ай бұрын
Yep, IF is life changing. The negative studies on it are poorly designed and KZfaqrs who are against it are misinformed.
@almaburns6562
@almaburns6562 10 ай бұрын
​​​​​​@@lexolus1308 You imply that IF can be "very dangerous" because they are fasting "for very long periods of time." Do you even know what 18:6 and 16:8 stand for? Do you realize this means they're EATING EVERY DAY over a period of six to eight hours? Not to mention, their allergies & asthma have disappeared with this IF regimen!
@WakeMtz
@WakeMtz 10 ай бұрын
FASTED EXERCISE, that is what yields the benefits. Intermittent fasting alone will do nothing without the exercise.
@vdfadfa
@vdfadfa 10 ай бұрын
Have been doing low carb diet & intermittent fasting for 10 yrs, never felt or looked better! Am regularly told I look younger according to my friends of similar age. Food conglomerates are likey not happy with intermittent fasting trend lol
@leopoldoenriquez2526
@leopoldoenriquez2526 6 ай бұрын
I totally agree with you. IF has changed my life for the better and reversed my pre-diabetes diagnosis. I have much less cravings for sweets and I have lost and kept the weight off for over 6 yrs now.
@chuckleezodiac24
@chuckleezodiac24 6 ай бұрын
i look & feel better than you... without intermittent fasting.
@theprophet2444
@theprophet2444 5 ай бұрын
It's all because that's natural for your body. we aren't meant to eat all the time and need some cool off phase, evolution can't keep up with us eating all the time
@TheGkmasta
@TheGkmasta 5 ай бұрын
Yeah, this is old science. New studies show you can synthesize much more protein in one sitting than previously thought. Also, Bryan Johnson has spent millions going over the research and he incorporates IF into his routine. I personally would recommend two meals a day in a six or eight hour feeding window.
@trail.blazer
@trail.blazer 5 ай бұрын
@@chuckleezodiac24 That's a statement that you probably do not have any evidence to support. How can you claim you feel better than someone else?! As for looking better, that would be a matter of opinion.
@amedeocalandriello756
@amedeocalandriello756 10 ай бұрын
When I used to do my fasts 18/6, I did the opposite. I started my fasts at like noon, then i would ear from like 6am to noon with a workout somewhere in that window. It's anecdotal, but i always felt great and managed to build muscle and stayed very lean.
@donwinston
@donwinston 10 ай бұрын
All forms of fasting are a gimmick. Extreme versions like one meal a day, every other day, ...etc are downright unhealthy.
@mco51193
@mco51193 10 ай бұрын
⁠@@donwinstonSays a guy that has clearly never done a moment of research on this topic.
@donwinston
@donwinston 10 ай бұрын
@@mco51193 No reputable health authority or dietician will recommend anyone do any kind of fasting. The claims about fasting are completely bogus.
@neilgunns8391
@neilgunns8391 10 ай бұрын
Doctors are still using BMi to tell if you’re overweight. They’re in the stone ages. According to that ridiculous BMi I’m almost obese and so is every other muscled athlete. They’ll also tell you that a calorie is a calorie. Another stupid Stone Age way of thinking. So eating 2000 calories of jellybeans is the same as 2k of steak. Clearly eating different things affects the body differently.
@Drgluee
@Drgluee 10 ай бұрын
In other videos, he recommends that shift to start your consumption window in the morning if you decide to fast so breakfast isn't skipped.
@manmoth4
@manmoth4 10 ай бұрын
So they're literally killing your gains
@Conversationstarter101
@Conversationstarter101 10 ай бұрын
🤣👋
@DrBradStanfield
@DrBradStanfield 10 ай бұрын
Yup
@theyetti90
@theyetti90 10 ай бұрын
😂
@thereignofthezero225
@thereignofthezero225 10 ай бұрын
Killing their brains too haha.
@heyyou9839
@heyyou9839 10 ай бұрын
Elevated blood glucose because of fasting is not problematic if it doesn’t lead to a huge surge of insulin with a huge reactive hypoglycaemic response. In fact, if you read the abstract properly, it is the delayed and flattened insulin response (A GOOD THING) from one meal a day, which leads to the higher blood glucose. And that’s fine - fasting therefore prevents an insulin surge. Insulin is a problem, not transiently higher blood glucose, because insulin causes of reactive, hypoglycaemia, and because of the fat storage properties of insulin.
@davidperfette1425
@davidperfette1425 10 ай бұрын
Autophagy aside, plenty of literature and research demonstrates the many benefits of intermittent fasting. Andrew Huberman did an excellent two-hour podcast, synthesizing all the research and clarifying the benefits. Yes, IF can work against maintaining muscle, but it doesn't have to. It is very difficult to get the prescribed ideal amount of protein in our diets to begin with. IF doesn't restrict protein intake. It's common to associate two meals a day with proper IF protocols, but there's no reason you can't eat three meals within your eating window. Or, if you want to try to stick to two meals, you can always eat two of the three meals closer together. E.g. 10am breakfast and 12pm lunch. You're still likely to be digesting the earlier meal, so that could be akin to one extended meal. The point is you have the opportunity to get the same amount of protein while doing IF that you otherwise would. I regularly weight train and run, and I've been able to build and maintain muscle while doing IF, and I'm 56yrs old. Also, I have better workouts while in a fasted state, so it's actually contributing to muscle building and maintenance.
@MrRadamantz
@MrRadamantz 10 ай бұрын
Andrew Huberman is not a doctor and is quick to overhype various understudied "snake oils" that end up not working
@bartl.7390
@bartl.7390 10 ай бұрын
two meals a day is TRE not IF and there is hardly autophagy occurring in any fast under 24 hours.
@BakamonNO
@BakamonNO 10 ай бұрын
I work out 5 days a week in IF state. And I outperform most people. Doing resistance training in a fasted state is amazing
@bigwombat7286
@bigwombat7286 10 ай бұрын
@@DaCon369 The body is fantastically complex. Maybe in a few years AI will help us sort out exactly how it works.
@davidperfette1425
@davidperfette1425 10 ай бұрын
@@DaCon369 He gives a cursory look at these studies. He doesn't seem interested in examining them deeply. There's a difference between statistical and clinical significance which he ignores examining.
@trogpo
@trogpo 8 ай бұрын
As to Metformin for non diabetes, I can tell from my own experience that it makes the muscles prone to tears. I do high impact sprinting and jumping, and while I was on Metformin I suffered from numerous muscle tears in the quads and hamstrings. It was just crazy. After giving up Metformin, the problem stopped completely.
@Chris_Faraday
@Chris_Faraday 6 ай бұрын
Whoa yeah - it will also make you diabetic in time
@erastvandoren
@erastvandoren 5 ай бұрын
Exercise is stronger than metformin and acts via the same pathways.
@AP-my7sc
@AP-my7sc 5 ай бұрын
it also increases my HR significantly
@trogpo
@trogpo 5 ай бұрын
@@AP-my7sc Thanks. What is HR?
@AP-my7sc
@AP-my7sc 5 ай бұрын
Heart rate : ) And I believe the mechanism could be related to the fact that metformin is toxic to mitochondria, blocking part of it's energy producing components; thus, although just a theory if the heart produces less energy (ATP) for contraction it would need to beat faster to deliver the same amount of blood to the body@@trogpo
@Pluvo2for1
@Pluvo2for1 10 ай бұрын
Loving this video Brad. And your reversal on protein is a credit to your honesty.
@0626love
@0626love 10 ай бұрын
or maybe the influence of big meat agro 🤣😂
@stefanisilva2493
@stefanisilva2493 10 ай бұрын
@@0626love More the influence of the bodybuilding trend and people wanting to look good being very angry on this muscle/ protein subject. Valter Longo shows very clearly that long living populations are not the most muscular folks but no one wants to look like normal thin people, we rather live less and reach that AEs enhanced celebrity look.
@walt1955
@walt1955 10 ай бұрын
The protein calculations from the papers shown here are based on people attempting to build muscle mass. For the average sedentary adult, the Mayo Clinic and the CDC recommend about half as much protein.
@Drgluee
@Drgluee 10 ай бұрын
That's correct, he also explains why everyone should build muscle mass to extend life expectancy. Being sedentary alone increases CVD.
@jaredscotton8601
@jaredscotton8601 5 ай бұрын
And Mayo Clinic and cdc don’t give good health advice
@nerolowell2320
@nerolowell2320 5 ай бұрын
the Mayo clinic and especially the CDC also recommended the Covid Vaccine plus boosters !!!
@Len1977gt
@Len1977gt 5 ай бұрын
@@Drgluee muscle doest extend life, diet and cardio excercise does
@Drgluee
@Drgluee 5 ай бұрын
@@Len1977gt Dr Stanfield, backs it up with research, not baseless claims. The muscle itself does extend life, the ability to help prevent falls in older individuals. Please watch his videos.. If you still say BS, you are simply ignoring science.
@LoreOfTheRingsYT
@LoreOfTheRingsYT 10 ай бұрын
I am a healthy young 24 year old building strength. I recently quit intermittent fasting and started bulking instead. My results has skyrocketed. The benefits I miss though, is the cognition, because on intermittent fasting you have an insane focus. But I am very happy with my new high protein diet!
@thebigpicture2032
@thebigpicture2032 8 ай бұрын
Old unhealthy people seem to love IF, likely because it stops them from eating too much.
@GabrielCazorlaPersson1
@GabrielCazorlaPersson1 7 ай бұрын
Same here, I am 24 too. I lost weight unintentionally when doing IF, now I am bulking and progressing fast in the gym with 6x per week and 5 meals a day. The cognition benefits I am not so sure, neither I nor another friend that tried it found any cognitive benefit, it might be pure psychological suggestion.
@FreeformRock
@FreeformRock 5 ай бұрын
How many hours were you fasting?
@lotsaspaghettimamaluigi
@lotsaspaghettimamaluigi 5 ай бұрын
Your loss of focus could be due to other factors like what you bulk on
@charlesfuchs
@charlesfuchs 5 ай бұрын
The bigger you get, the earlier your lifespan will get. Its documented.
@paulodeoliveira7725
@paulodeoliveira7725 10 ай бұрын
Thank a lot for having the luck to still have true and honest scientists that are willing to, not sell another product, but offer us the simple truths about age and how to fix it.
@katherinegarelli2889
@katherinegarelli2889 10 ай бұрын
Really glad to have you help us through so much information bad and good.
@westfieldartworks8188
@westfieldartworks8188 10 ай бұрын
I did a Low Protein High Carb Vegan diet for one year back in 2016 -2017. I looked awful. I felt awful. I had brain fog and depression. I was experiencing PVC's when taking my pulse at the wrist ( "skipping heartbeats "). My hair was flat and it seemed that my entire body drooped. 50 grams Plant protein per day for a 210 lb. man doing resistance training and HIT is not enough. All things improved when I brought back eggs and fish and some dairy back into my diet. Thanks for the video, Doc.
@westfieldartworks8188
@westfieldartworks8188 10 ай бұрын
@@helena_5456 Oh, you hit it right on the head, Helena. Something was very OFF about that high carb, low protein, low fat approach.. My blood pressure during that diet was good and low...BUT...it actually improved further when I got OFF the high carb Vegan diet. PVC's " skipping heart beat." was having about (100 to 300) per hour, now I have about (None to 5) per hour. Women started finding me attractive again, and my strength increased along with my sexual drive. The hair on my head was thick again, and no more sitting in the basement experiencing depressive moods. Thanks for your post.
@manmoth4
@manmoth4 10 ай бұрын
I used to have 10,000+ PVCs a day, not fun. Down to a few dozen by controlling inflammation
@glynemartin
@glynemartin 10 ай бұрын
Who said that high carb low fat meant low protein?😅😅😅
@westfieldartworks8188
@westfieldartworks8188 10 ай бұрын
@@glynemartin Well, it was the idea of several online youtube docs and influencers that were pushing more of an 80/10/10 style diet. LOTS of natural high fiber carbs, low fat, and lower plant based protein. They were suggesting that eggs, poultry, red meat, dairy, and fish were not good for overall heart health. So eliminating all those protein sources, along with only putting in plant based protein sources, gave me a protein intake of 50 -70 grams per day, which comes to 200 to 280 calories, which is approximately the 10% percent protein intake that they were suggesting. I had never done a diet such as this. I would not recommend it for most people, particularly if you're lifing weights and doing hard interval cardio. I weighed about 220 lbs at the time I started this diet.
@glynemartin
@glynemartin 10 ай бұрын
@westfieldartworks8188 That's because all those animal products deliver their protein gift-wrapped in a costly health-compromising package. You haven't heard?
@patdill
@patdill 10 ай бұрын
46 yrs old, felt sluggish, sick 3+ times a year. Started ACV / lemon in morning, no breakfast for 1 year. Complete 1/2 Ironman in 5 and half hours, 5k time is 17 minutes, 5 minutes for one mile, not sick…I’ll stick with this plan and adjust if needed, but this has been life changing for me.
@fatillacing4131
@fatillacing4131 10 ай бұрын
@@tafdiz apple cider vinegar. So if pattdill answers is it filtered or with mother?
@NathanaelMontgomery
@NathanaelMontgomery 10 ай бұрын
Dr Stanfield loves him some counter-popular opinion. It's a great strategy for click maximization.
@antonystringfellow5152
@antonystringfellow5152 10 ай бұрын
@@NathanaelMontgomery Dr Stanfield isn't really interested in opinion and he doesn't generally offer his. He focuses on the facts. Very important to be able to make the distinction.
@antonystringfellow5152
@antonystringfellow5152 10 ай бұрын
@@tafdiz It's apple cider vinegar, which is acetic acid and water. The source doesn't really make any difference but some like to think it does.
@Lieutenant-Dan
@Lieutenant-Dan 10 ай бұрын
This is the issue with anecdotes. Was skipping breakfast and having ACV & lemon the ONLY changes you made to your lifestyle and diet? Did you start exercising more and eating better? A lot of people start other healthy habits when they decide to make a change.
@sulistyowatisulistyowati9474
@sulistyowatisulistyowati9474 10 ай бұрын
I think fasting is great, that's why I and other muslim have to fast during the Ramadhan month, I have been doing IF since 2018 and I feel way much much better than before doing IF, I never get sick easily
@thomasf.769
@thomasf.769 10 ай бұрын
Your reports continually make a lot of sense for those of us looking for the “magic” pill. Thanks.
@jshtaway1
@jshtaway1 10 ай бұрын
The vitamin e part is more nuanced since manufacturers may be oxidizing vitamin e in production so that you’re not actually taking an antioxidant
@bryansmith725
@bryansmith725 5 ай бұрын
And most vitamin e supplements contain only alpha tocopherol (usually synthetic, not the same as natural), and don't include beta, delta and gamma tocopherols. Gamma is particularly effective against the peroxynitrite free radical.
@cowanthegreat8966
@cowanthegreat8966 5 ай бұрын
Starting to turn off supplements, not because I don't think they may be beneficial, but because few of these companies that produce them submit them for independent third party testing. Turns out most contaminants, use ingredients from the PRC, and many aren't giving you what's on the label. I'm out till these companies provide objective testing of their products.
@arihaviv8510
@arihaviv8510 4 ай бұрын
The same problem is with omega 3 supplements. You really need to get it from fresh food
@hineko_
@hineko_ 10 ай бұрын
They compare intermittent fasting to calorie restriction, not to "normal" diet. Calorie restriction is a diet which cannot be sustained as it causes person's suffering in the long run. My father was on this diet. Yes he lost weight but he spent a year being depressed and when he returned to his usual habbits he quickly gained weight. Intermittent fasting though cause problems only in the beginning, but when you got used to it, it becomes natural and easy.
@Saucebawss
@Saucebawss 10 ай бұрын
Great work and thanks for the easy takeaway to ignore longevity influencers 😂 But seriously, super helpful and really appreciate breaking this down with studies to back your views.
@aafursa
@aafursa 10 ай бұрын
I don’t agree with you about the Intermittent fasting. It has many benefits for the human body, as with everything you have to find a way that it works for you not against. Too many people eat too many times a day never giving their digestive system a break. I will say though, I haven’t heard about the reservatrol being a poison- that’s something I will have to look into.
@crazycrazycrazyadam
@crazycrazycrazyadam 10 ай бұрын
As someone who has DRY fasted for 7 days, the results are incredible, but it is not something easily done. Amazing deep autophagy and stem cell activation, but it will be the most grueling physically and mentally challenging thing you ever do.
@levondarratt787
@levondarratt787 10 ай бұрын
90 percent of crap life to life 1% longer - you do the math
@marylamb6063
@marylamb6063 2 ай бұрын
My grandmother lived to 103. She smoked like a chimney and was obese. She never exercised and hated veggies. Yet she never had diabetes, high blood pressure, arthritis, cancer, nothing. The only thing she had was a completely calm and laid back personality. My mother is 90 and is the same way, no health issues but 100% laid back. These two didn't try to live long. They just lived.
@stevemartin7464
@stevemartin7464 Ай бұрын
I think the relaxed approach to life helps a lot.
@Michael-4
@Michael-4 4 ай бұрын
With intermittent fasting you are not just benefitting from calorie restriction, you are also reducing insulin under the graph.
@hellobeautiful3301
@hellobeautiful3301 Ай бұрын
Exactly. He looks at IF from a very narrow angle. He doesn't have a wholistic view. Not eating at night is amazing and totally natural.
@edvedder7835
@edvedder7835 10 ай бұрын
Great content again today Brad. Thank you.
@Darkpixel2
@Darkpixel2 10 ай бұрын
I must admit I am completely lost now, intermittent fasting was supposed to be amazing…I kept all my muscle mass did not lose belly fat though. But feel great.
@CaptnYestrday
@CaptnYestrday 10 ай бұрын
When you feel great, you have the motivation and willpower to do anything. Have you thought of slowly trying to change the consistency of your eating window? You don't have to cut carbs but shift the balance in favor of protein. Also be careful of metabolism lowering. It can happen during strict intermittent fasting
@BakamonNO
@BakamonNO 10 ай бұрын
IF is amazing.. Brad is not a God my man. Keep it up
@Cenot4ph
@Cenot4ph 10 ай бұрын
Fasting multi day has all the benefits, intra day I don't think it's that great
@vdfadfa
@vdfadfa 10 ай бұрын
Do what works for you! I've been doing low carb diet & intermittent fasting for 10 yrs, I'm 55 and feel & looked better than I did in my 30's. Truely life changing
@richardmcdermott6745
@richardmcdermott6745 10 ай бұрын
My wife and I did 16/8 IF for about four years and then switched to a 48 hour fast every two weeks. I think the benefits of autofagy are too great to ignore. Just my opinion after watching videos and reading articles. Kudo's to Dr. Stanfield for staying objective and following the data!
@harm-reduction
@harm-reduction 9 ай бұрын
thanks for making combined video with all of the actual issues. Its very hard to track the information scattered around bit by bit from different videos
@Naatewaard
@Naatewaard 10 ай бұрын
Intermittent fasting has benefits outside of calorie restriction. Like self discipline, learning to not use food as a comfort tool and also gives your organs, more so liver than anything else time to repair and function without having to deal with all the crap people put into themselves at all times. It's also a good indicator for health, if you struggle to fast for 16 hours, feeling woozy or whatnot, you're prob on your way or already are pre diabetic.
@clownbackpainrick6581
@clownbackpainrick6581 7 ай бұрын
Yes that are important aspects. I do Omad less strict for years and since 2,5 years with 95-97 success rate over the year. To quantify this in respect of helth benefits would be nice, but of course I think mankind has not the tools for this. Even to quantify autophagy and from authophagy resulting health benefits seems not an easy task.
@tomdry2324
@tomdry2324 10 ай бұрын
I am not a fan of reservatrol either but I think you could improve the argument you make there. I really don't think it's crazy that a substance could have a positive effect at low doses (hormetic stressor) and a negative effect at higher doses. As an example, think amount something like sunlight (good in small doses, damaging in high doses).
@StKrane
@StKrane 10 ай бұрын
Thank you very much! It’s really a service you’re giving here. I recently came across a video from that Dr. singing the praises of resveratrol and instantly thought of you mentioning this massive flaw in the lab. We need to stick to the basics and use them well. Thank you so much!
@arttoegemann
@arttoegemann 10 ай бұрын
Should the luminescent dye be the supplement?
@tayokarate
@tayokarate 10 ай бұрын
​@@arttoegemannlol yeah right my exact thought😅😅😅 unfortunately I guess dyes do have toxic effects
@BluegillGreg
@BluegillGreg 10 ай бұрын
The first problem vitamin E supplementation advocates ran into was that it was very difficult to come up with a vitamin E deficient diet.
@giorgioborelli4497
@giorgioborelli4497 10 ай бұрын
Great info , with real data on the back. Good job !!!
@jerrydesu
@jerrydesu 10 ай бұрын
Wow, that's quite a thorough presentation. So a 4 day fast is better for autophagy than intermittent fasting which is good for calorie reduction but be careful to get enough protein.
@omvilla7469
@omvilla7469 10 ай бұрын
It is actually quite a presentation, but with lots of partial truths. Very sad. Some info seems useful, but partial truths... aren't they lies?? All we can do is try to keep informed and uptodate... seek more information, you will quickly realize what is and what is Not... Sad presentation... sorry... Don't let your feud with Dr. Sinclair look for any stuff to post and make money Dr. Brad. Clearly you are also making money out of Dr. Sinclair... Ironically...😅
@cryptodoodle7506
@cryptodoodle7506 10 ай бұрын
​@omvilla7469 this is basically my thinking, his niche has become disagreeing with everything to get the $$.
@Morgainz88
@Morgainz88 10 ай бұрын
It takes a few days for the body to use up all the glycogen stores. I try to do one every few months. Just don't weight train for muscle growth the day before or during the fast. Some reduced volume training is muscle protective though.
@peterpan408
@peterpan408 10 ай бұрын
I think we might need to eat protein and train every 4 hours.. That's a lot of shakes and training 🤣 If I'm not training, I eat my BMR or less in high protein diet. If I am training I eat a surplus of BMR in high protein diet.
@Myndir
@Myndir 5 ай бұрын
The point is that you'd need to fast for 4 days to get similar sorts of autophagy to the mice studies (because mice have a much more active metabolism) but 4 days of fasting obviously brings quite a lot of additional health problems. The benefits from IF can be largely or entirely explained by the benefits of calorie restriction. If people find that IF is the best way for them to keep their calories under control, it could be a good idea; it depends on the costs of protein deficits vs. the benefits of calorie restriction, which will depend on individual factors e.g. exercise patterns and food options.
@phonixsolomon6275
@phonixsolomon6275 10 ай бұрын
What do you think, is he talking about Bryan Johnson or his arch enemy David Sinclair?
@eatdabugz
@eatdabugz 10 ай бұрын
😂
@tomu4725
@tomu4725 10 ай бұрын
I don't know but Bryan Johnson has a team of actual doctors using the latest info on aging to try to see what works on his biomarkers. Again, a team of actual, professional doctors. If we wait for the FDA and the clinical trial process, we'll probably be no longer here. I support him and if folks don't like it THEN DONT FOLLOW HIM
@EasternRomeOrthodoxy
@EasternRomeOrthodoxy 10 ай бұрын
@@eatdabugz 🔥🇺🇲😂💥💥💥🔫🤣🇷🇺
@nunyabeezwacks1408
@nunyabeezwacks1408 10 ай бұрын
Both
@YaYippieYeah
@YaYippieYeah 10 ай бұрын
Johnson for sure. And Valter Longo maybe.
@claudettesechler149
@claudettesechler149 10 ай бұрын
Thanks for digging in and keeping us aware and the preventatives! Appreciate your discussion and sharing your knowledge
@mattc3510
@mattc3510 8 ай бұрын
This video I’ve seen all year. Thank you so much
@Pencilmadeofwood
@Pencilmadeofwood 10 ай бұрын
I think you're doing a great job helping people find out what is good for their health and what actually isn't. Thanks!
@tadghsmith1457
@tadghsmith1457 10 ай бұрын
@JohnnytNatural Do you have studies to base that on?
@MochaZilla
@MochaZilla 10 ай бұрын
​​@@tadghsmith1457haha nope just his own anecdotal bias lmao
@ricknelsonm
@ricknelsonm 10 ай бұрын
Your wrong, and your out of it, Dr. Berg is the king here, so take that!!!!@JohnnytNatural
@musashi542
@musashi542 10 ай бұрын
@@tadghsmith1457 surelly you have studies that prove otherwise
@MsSuperww
@MsSuperww 9 ай бұрын
​@@tadghsmith1457Yet, apparently, arguing "based on studies" do not solve this problem either, since both this doctor and his intellectual opponents do it, and yet can't seem to agree about the right answer...
@richrich8487
@richrich8487 10 ай бұрын
Look, Brad is a KZfaq influencer. These videos are clip bate. There are so many studies on a lot of these topics it is not that hard to pick a side and make your point. Just take the most popular trends, oppose it, and boom, you get views. Nobody knows with 100% certainty about the efficacy of these trends.
@azzyfreeman
@azzyfreeman 10 ай бұрын
But he seems to be consistent and does not have any conflict of interest
@Proestor3810
@Proestor3810 10 ай бұрын
@@azzyfreeman lol the discussion in the studies he cites even contrast what he says. He isn't a researcher and clearly cherry picks. Not saying you should follow other influencers brad has some good videos. But this one is clearly cherry picking for his personal vendetta against researchers like Sinclair
@mitahantahanlaittais
@mitahantahanlaittais 10 ай бұрын
@@Proestor3810 Seems to mirror pretty well what dr. Peter Attia does.
@thepontiacbandit7329
@thepontiacbandit7329 10 ай бұрын
This argument may be true, but you haven't supplied any concrete data to support it. Saying there's a lot of research on everything, and it's contradictory, is too general, and actually means nothing unless you point out to a specific claim and show the contrary.
@Proestor3810
@Proestor3810 10 ай бұрын
@@thepontiacbandit7329 ​ @thepontiacbandit7329 I did in a further comment, but as you like: look at the paper of IF on blood glucose. If you read the paper it states in the conlcusion: "Our findings show that consumption of one unusually large meal per day worsens morning glucose tolerance compared with an isocaloric diet spread across 3 meals. However, when on 1 meal per day, the subjects would have eaten less than those on 3 meals per day if we had not asked them to consume the same amount of food that they normally eat on a 3-meals-per-day schedul" --> overfeeding a clear bias same paper: "The OGTTs were performed in the morning. Therefore, when on the 1-meal-per-day diet, the subjects had consumed a much greater amount of food in proximity to the OGTT compared with subjects on 3 meals per day, which could have influenced morning insulin sensitivity." These are clear limitations, clearly mentioned in the conclusion (not hidden when reading between the lines). I do not get why Brad ignores these statements. Honest question, but you think his conclusions are fair if you take this into account.
@rappar9673
@rappar9673 10 ай бұрын
Thank you for the video Dr. Brad, very informative.
@peterc7144
@peterc7144 10 ай бұрын
Thank you, this was eye opening and helpful. In this world where there is so much info noise it is difficult to know whom to believe and what diet/advice to follow. By sharing your advice, you are helping us in this matter. Thank you for your great work!
@gettingstuffdoneright5332
@gettingstuffdoneright5332 10 ай бұрын
Thank you for this video and for your road map, they are a gift, and I've shared it with everyone I know & love. Much gratitude and all the best to you and your family, take care
@wonders6706
@wonders6706 10 ай бұрын
I think you just don't like David Sinclair. 😂
@ÁzsiábaSzakadtam
@ÁzsiábaSzakadtam 9 ай бұрын
Who does? Fake AF. See story of resvaratrol.
@EricCosner
@EricCosner 10 ай бұрын
It's interesting how much is changing with longevity. I have pretty much stopped IF. I am exercising more and I have increased my protein intake. I am getting my protein from multiple sources, 3 times a day. I take NMN, Creatine and Taurine in a protein shake before I run or strength train. This is the no doubt the best shape I've ever been in, and I'm getting closer and closer to having a 6 pack for the first time in my life at 43 years old. 💪😊
@vickyverma6852
@vickyverma6852 8 ай бұрын
Cool, and you look a lot younger than 43 in your latest videos. I'd love to know your full fitness routine and diet.
@MariaPeredaPhD
@MariaPeredaPhD 6 ай бұрын
Pure Perfection! I thank you very much for the high-quality presentation. It helps a lot!
@naimarestoringdivinity7938
@naimarestoringdivinity7938 10 ай бұрын
The intermittent fasting one I have to say is one of the reasons I grew up with so many elders that were healthy
@DashingPartyCrasher
@DashingPartyCrasher 10 ай бұрын
You might because they were intermittent fasting? Or not fasting?
@walterdejean7532
@walterdejean7532 10 ай бұрын
exactly.... fasting may not be shown to work in his lab studies, but in real life its worked for thousands of years....
@MNkno
@MNkno 10 ай бұрын
The best reaction I've heard to "intermittent fasting" was my mother's - "You mean, stop constantly stuffing your face in between meals".
@mrwolf750
@mrwolf750 10 ай бұрын
The next miracle supplement will be the fluorescent dye used in the resveratrol lab tests.
@evcisnso
@evcisnso 10 ай бұрын
Dr. Stanfield, another excellent and well researched video. Do your concerns about resveratrol apply to pterostilbene too?
@patrickcrombmusic
@patrickcrombmusic 10 ай бұрын
another excellent video. very grateful for what you do Dr Stanfield.
@tempeman101
@tempeman101 10 ай бұрын
Interesting video. I agree with all the items except perhaps IF. As many people have said, you can obtain ideal levels of protein even on IF. For me I never feel hungry in the mornings anyway. I will be interesting to see the debate unfold IF vs no IF. I believe there are significant benefits with an extended fast (4-5 days) at least on an annual basis.
@hurbogal
@hurbogal 10 ай бұрын
May I ask what you think are the benefits of an extended fast? Some will power to fast that long!
@hiraijo1582
@hiraijo1582 9 ай бұрын
@@hurbogal building stemcells in your immune system
@bruceb5481
@bruceb5481 10 ай бұрын
I'm an active 81 year old and engage in fun activities that require strength such as skiing, hiking and especially mountain biking (rocks, roots and ups and downs) swimming and paddleboarding. I have experimented with intermittent fasting only to find a decline in strength and stamina. No more IF for me.
@Hack3r91
@Hack3r91 10 ай бұрын
Congratulations! I hope to get to feel that good at your age sir.
@lexolus1308
@lexolus1308 10 ай бұрын
Yeah, you need to keep those vitamins/nutrients/carbs etc high all day, breakfast is super important because when you sleep you deplete a loot of nutrients and vitamines in exchange to boost regeneration and its very important to get those early macros to feel better the hole day, and if you only eat once a day you expend most of the day low in vitamins etc and it can be very dangerous if you are older or have any vitamin deficiency, thats why they tell you to consult a dieticianand get medical checks first, and if you just eat normal 4-5 times a day you are always safer
@DrBradStanfield
@DrBradStanfield 10 ай бұрын
Thank you for sharing
@draconisdragonheart4248
@draconisdragonheart4248 10 ай бұрын
Exactly, no one can gain muscle if they are fasting. They need more protein throughout the day for their muscles.
@MNkno
@MNkno 10 ай бұрын
Good for you for listening to your body when testing a suggested strategy. A question: do you eat constantly throughout the day, with snacks and "energy drinks" while you are hiking, moutain biking, swimming and skiing?
@Vedicarts108
@Vedicarts108 9 ай бұрын
Amazing video, I totally get this after listening to a lot of people online: this is a high value video. Great job!
@Corkfish1
@Corkfish1 9 ай бұрын
This explains why people in health food stores look so unhealthy
@spacejaime
@spacejaime 10 ай бұрын
Excellent as always. I have no choice but to take Metformin and Jardiance every day, but I threw away the resveratrol months ago when I first say your video on the dye used during the clinical trials as the trigger for the sirtuin 2's. I'm also taking NAD+, NAC and Taurine. I wonder if these "anti-aging" supplements are of any benefit. Thanks!
@mndeg
@mndeg 10 ай бұрын
NAD+ is too big to get into cells. do you mean NMN or NR?
@spacejaime
@spacejaime 10 ай бұрын
@@mndeg - NAD+ in capsule form. My endocrinologist likes NAD+ in injectable form, but it is expensive. Maybe I'm wasting my money in capsule form.
@ehxhhd477
@ehxhhd477 10 ай бұрын
Multiple human studies of resverotral being negative? He's got like 5 out of thousands.
@bradparkinson7169
@bradparkinson7169 10 ай бұрын
Good work Brad. Just a quick correction, at 1:27 you said "When mice are given mTOR" I believe you were supposed to say Rapamycin instead of mTOR. A minor glitch but when you do such good work it stands out. Cheers for all the great content.
@edwardsmith5650
@edwardsmith5650 4 ай бұрын
I'll bet the mice don't think the lab is a safe environment.
@WakeMtz
@WakeMtz 10 ай бұрын
Just a note, intermittent fasting and fasted cardio are very very different regarding the effects and benefits. Most people that advocate for intermittent fasting because they've had great results, do fasted exercise. So someone sedentary that does intermittent fasting will not have the same effects as a fitness influencer doing fasted exercise. Fasted exercise does have an impact on insulin, glucose, autophagy, etc. And no, eating protein every 3hrs will not make a difference if you do strength training and match your protein intake.
@davin8r
@davin8r 10 ай бұрын
One can get the benefits of autophagy without marked muscle loss by doing periodic 5-day fasting-mimicking protocols (such as Prolon or a do-it-yourself version).
@TenantRepGuru
@TenantRepGuru 10 ай бұрын
Thank you for clarifying this for us doctor.
@persophone4554
@persophone4554 10 ай бұрын
As an oldie I prioritise protein, cardio sessions and weight training. I'm in better health and happier than before. BP and glucose are great,
@17losttrout
@17losttrout 10 ай бұрын
Excellent work, mate. Very well put together. Thank you from the UK. Love your country!
@dekumutant
@dekumutant 10 ай бұрын
Okay im going to need clarification on these intermittent fasting comments. How the hell is skipping breakfast meant to be bad for your insulin levels. Doesnt having it spike more lead to insulin resistance?
@WhySev89
@WhySev89 10 ай бұрын
I've adopted regular fasting for the past two years. Lost weight, lost the sleep apnea, more healthy than I've ever been. I dont think this doctor know he's talking about.
@mikeford5080
@mikeford5080 10 ай бұрын
how bad was your apnea? did you use a cpap machine? how much weight did you lose? I would love to get rid of the cpap machine!
@WhySev89
@WhySev89 10 ай бұрын
@@mikeford5080 It's pretty bad, I was overweight at 193lbs considering my height at 5'4. Starting prolonged fasting monthly for 2 years with intermittent fasting 2 meals a day. During the prolonged fasting, I did it for 2-3 days without eating mainly just on water. I'm down to 150lbs getting better sleep and feeling more energetic.
@brunonkowalski
@brunonkowalski 10 ай бұрын
IF is the only thing I see works very well for me and I've been doing it for over 6 years. I didn't also see any negative impact on my muscle mass.
@JesusGarcia-Digem
@JesusGarcia-Digem 10 ай бұрын
Ive been on OMAD for over a year, 2300 max calories. Mike Mentzer H.I.T heavy duty training is the best program for natty's like myself. Stay natty.
@thommilner
@thommilner 10 ай бұрын
Part of why I intermittent fast is to leave a long enough time gap after eating and before bedtime and I sleep much better when I do this. So what is the balance between sleep quality and well spaced out meals? Also I wonder Is a long 3-4 day fast beneficial once in a while, say every quarter year?
@joestone8576
@joestone8576 4 ай бұрын
absolutely excellent critique of the longevity clowns and grifters. The most important prevention protocol is to avoid frailty, but most of the longevity grifters are promoting a protocol that would accelerate sarcopenia.
@Beans-great
@Beans-great 10 ай бұрын
I’m 51 and been doing IF and sometimes OMAD for a good 4 years. I think I’m starting to lose a bit of muscle mass so I might need to start adding more protein.
@Simon-talks
@Simon-talks 10 ай бұрын
I'm 49 and been doing IF for 20 years and I have more muscle mass than I've ever had and I'm usually one of the most muscular guys in each gym I train in. It's easy to get 200 grams of protein per day, spread out across a 9 hour eating window. I don't know what these people are talking about but it's nonsense.....
@WakeMtz
@WakeMtz 10 ай бұрын
Don't buy on the 1.6g/kg bs. Bodybuilding community has known for decades that 2.2g/kg is what is necessary to maximize muscle mass. If you are concerned on muscle loss, try supplementing with HMB.
@vdfadfa
@vdfadfa 10 ай бұрын
I've been doing low carb diet & intermittent fasting for 10 yrs, I'm 55 and feel & looked better than I did in my 30's. Truely life changing. I'm constantly told how young I look. Results don't lie I bet the food & pharmaceutical industries are punching the air right now. LOL
@peterpan408
@peterpan408 10 ай бұрын
And strength training..
@dfoo75au
@dfoo75au 10 ай бұрын
This is the only channel where guidance is based on the latest research and evidence. Too many other channels are invested in what they preach in the past and are stubbornly stuck with ideology despite new evidence. I'm glad Dr Stanfield is always open to change his mind when he finds new evidence and that is why I am subscribed to his channel.
@charlesfuchs
@charlesfuchs 5 ай бұрын
Wrong
@galapalafala
@galapalafala 5 ай бұрын
The problem with nutrition science is that there's so much sample error and parameters that are very hard to control in these studies, that what we know today might turn out to be the opposite. Another issue is that there is so much variability per person that these research conclusions may not apply to you. Take this into consideration when making decisions.
@linnhagtvedt9930
@linnhagtvedt9930 9 ай бұрын
Thanks for all the good information.
@Pluvo2for1
@Pluvo2for1 10 ай бұрын
I've been trying to increase protein intake to the recommended level but it's really hard! I'm into protein powder now, but I don't really enjoy it.
@chandebrec5856
@chandebrec5856 10 ай бұрын
I have a dose -- 28 g powder, 25 g protein -- mixed into my big daily oatmeal breakfast
@DuncanPerryOfficial
@DuncanPerryOfficial 10 ай бұрын
Intermittent fasting is good for 3/4 days of the week max, as long as you're keeping you protein macro up. HIT or Heavy duty training on off days from Intermittent fasting will help you get the sufficient protein and recuperation for those days. I do Intermittent fasting and have gained muscle while reducing overall fat percentage naturally.
@tatianaa.3694
@tatianaa.3694 10 ай бұрын
Thanks for this information!!! ❤
@brettharter143
@brettharter143 4 ай бұрын
I did intermittent fasting and had my T levels done with bloodwork they were at pre-hypogonadal levels. Couldnt believe it
@ryanrojas9599
@ryanrojas9599 10 ай бұрын
you fail to mention that you were once one of those influencers, you have since deleted those videos.
@robertusga
@robertusga 10 ай бұрын
You mean he goes where the outcome data goes. If new data makes previous videos obsolete, leaving those up would be disingenuous no?
@FYS27121
@FYS27121 10 ай бұрын
Science changes constantly, new, better research comes out and it sometimes contradicts the previous findings. Being able to change your thinking based on new evidence is the scientific mind, staying rigid gets you nowhere. So he is actually doing everything right. What’s the point of keeping outdated info out for the public to watch and get confused.
@quantumfx2677
@quantumfx2677 10 ай бұрын
I'm 54 and still going strong and people believe I'm in my 30s, my protein is venison buffalo Elk squirrel fish and eggs. I've been strength training now for 41 years. I've been doing HIT since 1992 which is intense and brief training.
@nomandad2000
@nomandad2000 3 ай бұрын
Joe Rogan is that you?
@DerekFrazier2014
@DerekFrazier2014 10 ай бұрын
Thank you so much for information and I plan to space my protein input and have protein shake in the morning but I still feel better with a meal cutoff around 4 or 5 and fast till morning.
@user-iw4gc9vt9p
@user-iw4gc9vt9p 10 ай бұрын
This is the reason that I stick to “ keep it on moderation “ strategy on everything 😊
@kellicardaras2805
@kellicardaras2805 10 ай бұрын
What an eye opening video! Thank you so much for this information, Doc. You are a lifesaver!
@quantumfx2677
@quantumfx2677 10 ай бұрын
David Sinclair I believe is missing the big picture he focuses to much on supplements and mechanisms and not enough on building muscle he focus on mice and promotes calorie restriction and not enough on muscle, Muscle isn't there just to look good its actually doing something in your body. Do to advances we now have dinostic tools that we can see and measure in the body and what we find out is just how important building muscle really is for living longer and disease free. There are several types of aging pathways we now know that get activated only when we put on muscle. let's look to get a better understanding whats going on when we build muscle, testing was done on grip strength and what they learned is those that had stronger grip strength lived longer than those that didn't. So those that do squats and have stronger lower body will live longer as the lower body is one of the largest muscles on the body. Mitochondira disfunction is one of the problems as you age and working out is one way to prevent this as well as same as stem cell exhaustion and shortening telemere length. Extracellular vesicles get secreted when building muscle that carry growth factors and anti flamitory cells to prevent inflammation and inflammation is one reason why we age and get disease. So the belief in reducing calories, fasting, taking supplements and restricting calories we should really be focused on building muscle as there is actually a real science behind this. __ Dr.Adeel Khan is working with a company that's the first therapy in the world to block myostatin and have no side effects. One subcutaneous injection will last 1.5 to 2 years being completely safe. Regenerative medicine is our future if we can get rid of bad people in the wrong places.
@BakamonNO
@BakamonNO 10 ай бұрын
Sinclair recommends doing HIT and normal exercise. Also to get enough protein. He personally get's most of his protein from a plant based diet.
@quantumfx2677
@quantumfx2677 10 ай бұрын
@@BakamonNO I never seen that where he recommends HIT but I know when you lower your calorie intake you won't be able to HIT.
@ALucas73
@ALucas73 2 ай бұрын
He's moved on to primate testing and humans.
@stephaniecamp5729
@stephaniecamp5729 9 ай бұрын
Your amazing. Love your perspective and included medical papers and studies! You should sell T-shirts saying ‘You are not a mouse’ lol 😂 Take Care!!
@amyntas97jones29
@amyntas97jones29 10 ай бұрын
I'm 65 and have never been overweight. My total cholesterol was 9 and my tryglicerides were also very high. I also have mild fatty liver. I decided to cut out processed foods, and severely reduce carbs. I asked my doctor to put me on Crestor 5mg ( I didn't want to take a lipophilic statin). I started taking 3 grams of Niacin daily, whey protein, high dose omega 3, bergamot, vitamins B6, 12, D. My bloods not read: TC 3.8, HDL 1.6, LDL 2 and my tryglicerides are now 0.7. All liver enzymes are now normal. I also do resistance training and rucking and have good muscles mass. Just shows, one can turn things around.
@Contrarian1618
@Contrarian1618 10 ай бұрын
Relatively low protein diet is pretty typical for Blue zones like Okinawa for example. High protein doesn't automatically mean more muscle, resistance exercise should be prioritized first.
@missknight9
@missknight9 10 ай бұрын
This is a great video. I am confused about how the low protein diet part made the list. I have never heard anyone recommend that for longevity.
@grellis6483
@grellis6483 10 ай бұрын
It's exactly what Dr David Sinclair and many other delusional vegan fanatics believe.
@villetakoo
@villetakoo 10 ай бұрын
Then you haven't been following the leading longevity scientists.
@missknight9
@missknight9 10 ай бұрын
@@villetakoo just the ones worth following
@villetakoo
@villetakoo 10 ай бұрын
@@missknight9 I understand. Good news about people's bad habits always hits differently than for example guidelines to eat less meat, more veg.
@villetakoo
@villetakoo 10 ай бұрын
@@missknight9 out of curiosity, who do you follow if Dr Sinclair and Dr Longo are not on your list?
@wayneg266
@wayneg266 10 ай бұрын
Brilliant, I thank you for bringing the truth out
@joemurray8902
@joemurray8902 10 ай бұрын
Thanks Dr. Brad!
@ChrisPikeEnterprise
@ChrisPikeEnterprise 10 ай бұрын
I am going to send your video to a friend who is doing three of the things on your list. He has fallen down the Sinclair rabbit hole. I hope that your video is able to get through to him!
@jpsh75
@jpsh75 10 ай бұрын
Excellent Brad, keep up the good science-based work!
@Soulcoaxing
@Soulcoaxing 10 ай бұрын
Thanks for exposing David Sinclair’s fraudulent claims.
@DrBradStanfield
@DrBradStanfield 10 ай бұрын
Thank you for your support, you’re a legend
@micha3828
@micha3828 10 ай бұрын
May I ask about the protein intake: I know, it may be a small different, but should I count the ideal of 1,6g/kg in the fat free mass? Thank you - anf thank you for the video.
@petr6258
@petr6258 10 ай бұрын
Good question.
@davin8r
@davin8r 10 ай бұрын
In my view, a high protein diet in a person who is not doing intense resistance training is similar to giving metformin to a non-diabetic in that both can be harmful. All that protein is driving up mTOR (yes, acutely, but "acute" becomes "chronic" when you are spiking mTOR 4 or 5 times throughout the day). Isn't it possible to get *most* of the strength benefits from resistance training on a moderate protein diet, which will also reduce the mTOR spikes?
@gtrgtr8354
@gtrgtr8354 10 ай бұрын
Blue zone people have low protein diets and they live the longest..
@volos_olympus
@volos_olympus 10 ай бұрын
@@gtrgtr8354That’s a myth which only applies to Okinawans (the Japanese in general eat high carb).
@gtrgtr8354
@gtrgtr8354 10 ай бұрын
@@volos_olympus its not I am from one of blue zones, and I have been to some others too
@volos_olympus
@volos_olympus 10 ай бұрын
@@gtrgtr8354 Which one?
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