I've just started taking 5gms 3 x times a day for fibromyalgia/ chrinuc fatigue, on my first day, feeling hopeful, I have added Co enzyme q10 as this is supposed to push the ATP into the mitrochondria cells, also Vitamin B1 B5 and folic acid as deficiencies of these vitamins all produce fatigue symptoms. I'm also taking malic magnesium and inflammatory supplements, I'm on Alot but I have an eating disorder so I truely suspect fibromyalgia is cause due to nutrient deficiency and inflammation as I've literally lived on carbs and sugar, so I know the good gut bacteria that naturally produces ribose will be very limited without the supplements