I have been following the longevity field since I was 50 and I’ll be 60 this year. Although without a doubt I’m healthier because of what I’ve learned and implemented, I’m frustrated that the magic time when meaningful longevity technology is available is always ten years away. It was ten years away ten years ago when I started.

I live for quality over quantity. I’m 63 and probably feel the best I’ve ever felt. Frame of mind is so important. If you sweat your age too much you are in trouble. Live life to its fullest and try to find your best health lifestyle and be happy. Also of course, get your spiritual life in order. Whatever that is for you. I’m wishing all of you the best life possible.👍

I'm like David's dad. I started around age 67 with Dr. Sinclair's recommendations. At 69 I just started an aerospace company.

Love love love David Sinclair and believe he is doing everything possible to bring healthy longevity to all of us.

Dr Sinclair is just an amazing gift to us from science.

Awesome! He seems much more optimistic than a few years ago on age reversal

On a 7 day fast right now for longevity. I'm 35 but never to early to start.

Seems Sinclairs Dad is the right model for us 65+ .Let's have him on this channel so we get a true picture of what he does and takes for his longevity.

1% of the population has "unbreakable bones". Scientists are studying them just like that they did with pcsk9. Peter, since Alzheimers and broken bones are a leading reason that prevents one leading a healthy old age life, would you speak to that research on bones in your next video? Thank you for this one. Enjoyed it thoroughly.

My father has been talking to me about about this topic for a couple of years. I am glad I finally took the time to hear what he wanted me to hear. Type 1 Diabetes, Addison's Disease, Asthma, Celiac Disease and 42 years old.

Definitely mindset. Nothing else matters near as much. I finally got over the hill. I'm 58 now, growing younger, and I still live on coffee, sugar and tobacco. Looking forward to the next 60 years.

These are the kind of conversations I live for.

David certainly looks younger than he did, in his earlier videos.

My goal is to live forever. So far so good.

You look 21 and I love how you wear your hair. You my new hero!!! I listen to every podcast you have. I am subscribed to you and have learned so much in a few days. Thanks I want to live to 150. I

Traductor al español por favor, me gusta escuchar a este gran científico David Sinclair

Can we all just stop for a second and noticed that Sinclair is coming up on 60 and yet he has the shimmering hair and glowing skin of somebody in their 20s? I mean seriously, look at the man. I'll have what he's having!

I have family members and loved ones who are over 60. please hurry up on that reverse aging research !

It’s always possible, always has been, always will be, possible.

Fantastic conversation and knowledge share. Thank you Peter and David! I admire your work and am grateful for the mindset you both embody.

I'm almost 77! So far, so good!

Aging is a part of life. It’s about time we got used to it. Cure diseases, try to stay healthy. But aging isn’t going to go away.

Love the picture of Watson and Crick with their DNA model, 1953. So cool. Really opened up knowledge of human bodies. Looks like you have it signed. What you are doing is the same revolution.

Badminton is important. It is essential part of longevity routine.

Dr. David Sinclair wow you look younger compared to 2022. ❤🙏

Too me, their is 2 main questions, when and will it be available for all.

Thanks for everything peter.

Thanks for a great video! David doesn’t cease to amaze us, and you too! But that music at the end of your video was too loud and too sudden. Would be great if you tone it down in line with the volume of your conversation throughout the video. Thanks for all your great work!!!

It feels realy like a conversation between two buddies. So Beautiful!

Best. Conversation. Ever.

Thank you guys! Fascinating chat. May I ask: If all of the intended science works, disease is cut down, quality of life improved, then what takes most people at the time of death with the limits have been reach? Just fatigue of the heart, for example? Do the normal things which get us now just get us 30yrs later? Thanks!

Very inspirational, thank you Peter

Timestamps would be nice, for those who want to get straight to the hacks/lifestyle changes 😄

No more coffee for me, I had a bad reaction to coffee last Saturday morning. Threw off my 16/8 IF program. So now I do eat breakfast, and ODDLY even though mealtimes have changed, my body still adheres to the IF concept.

“My spirit shall not abide in man for ever, for he is flesh; his days shall be a hundred and twenty years' (Gen. 6:3)

I have a brainwave entrainment device that helps relax me and lull my brain into a sleepy state. It's also helped me to meditate for much longer than I could before. I think the science of mental well-being is more important than longevity. Why would we want to live so long if we're miserable? But the same technologies that advance one advance the other.

I've started intermittent fasting and inflammation I've had for 5 years plus has vanished.

fantastic gentleman, thank you for bringing the subject forward in this KZfaq post. I think it's important to recognize that a lot of people who are in their senior years now; which would be 65 and older, budget a certain amount of money to make it to 84. I think a lot of people would be very frightened about living past that, they've retired and they don't have the funds to sustain their current life. Society would need an infrastructure of support I.e., food and lodging. Financially it would be a luxury for people that have the means to sustain their life past 75 years old or greater.

I was born completely blind in my right eye....I don't know what it is to see with two eyes..My dream is to see with 2 eyes. I am hoping Dr. St Clair will make my dream come true....

Apologies for my tablet pre posting some mistakes ,gratefulness to you Dr David Sinclair

23:12 I’m 22, I’m listening

Definitely our worst problems are aging and death. We see the acceleration of technology,how humans progressed in the last centuries and how humanity came from the stone age to what we have now. Think about it... It's an incredible long travel who is almost impossible to conceive,how we were a few thousands humans during an extended time and we could still survive until now. Being alive and healthy is the most precious condition we all have...it's totally normal to seek negligible senescence and push forward in this direction. We should put all our strengh on this.

Thank you for this video I watch all of your videos I don't know what it is about you David Sinclair but something about you that gets me hooked every single time I hear you I think I feel a sense of connection I get you I'm very optimistic about always proving people wrong whatever I'm trying to prove because I believe that much in myself and as you do yourself so that's one thing that I admire and the realization that I've never seen another man be as bold and forth telling about a subject that most scientists wouldn't dare cover study talk about to the public so kudos to you everything you've talked about if applied works everything you talk about not only works but makes sense someone called you Peter Pan once I think they're right and you've accomplished all of this with very little sleep so I also have that problem yet I've accomplished many things as well not on your level but it's true it's hard to function with very little sleep but hi hi hi kudos to you what does it mean why some people sleep really deep and good and others don't I don't understand but I do know this much I will work on mine as well God bless and take care and I'll pray that you get better sleep!

thank you

Thank you from the heart David! ❤

Brilliant I was waiting for another DS interview.

I appreciate the info and wisdom. I tried to buy the glucose monitor but was scared to give all of the personal data required. I didn't see and option to skip that.

What do you think about NMN is banned?

Dear Peter , I just tried to go into the link you gave us but did not com up ,there seems to be a block as l am in Sydney Australia? How do we get through ? I do have other study links into US ?yours sincerely M

I signed up at Tally a long time ago but they still don’t ship International and I live in Rome. I need them to hurry up!

Im very happy that his father is still there. Wow! How fantastic ! When I woke up earlier because of the great nad plus I'm not sure if I try too continue sleeping or stay awake. I want have unlimited physical immortality. I couldn't imagine too die

I have been listening to Sinclair for last 5-6 years. His optimism is accelerating at a rate faster than Moores' law. He used to say we might see 10-15 years rejuvenation within our life time or soon after , to now fully aligning with what Kurzweil used to say. Sinclair used to say hope Kurzweil is true but it's still fantasy. George Church is more rational person who doesn't go about making too bold statements in media like Kurzweil which obviously made many to think Kurzweil as a jerk. Aubrey De Grey too lost many peoples confidence as he has been saying it's 20 years away for last 20 years. I think we should not speculate too much on time and focus more on the path.

Nothing lasts forever 💔

Sadly in the uk we are so far behind. There is no option for a full physical examination 😢

4:10 hmm wonder if they were vaccinated? 10:00 lol 14:35 😳 29:30 😎 31:00 epicness!

Love this looking forward to future exigencics

thank you for sharing that with everyone and making such an impact

I like David Sinclair, but I dislike that he is always using filters or light to blur his face, so that it seems younger. In the pictures, you can clearly see a difference. I love that he is so lean and certainly looks younger than his age, but let’s be more honest in front of the camera. Plus, I would recommend caution with some supplements that he is referring. I am not a scientist, but in respect to aging and everything else, it is probably better to stick to moderation and be careful with overdosing on exotic elements or supplements. Choose a good, balanced lifestyle and diet instead.

Maybe avoiding the Vax is a wise lifestyle choice too.😊

I’m disappointed in David Sinclair for partnering with a pharmaceutical company and fda to take away nmn

Also adding a face-lift to tablets and capsules make you look younger! Minimise then your food intake and stand on your feet all day long at least make your life span feel ever lasting.

I’ll setting for better cough medicine for now.. figure that out first

You have my 'bravo' for the dashboard...

so in 10 years he believes there will be some way of reversing a portion of our age? i guess we cant get more details on this yet. May I ask why he mentioned age 50? is there any reason we cant get our age down to 21 in the future?

12:50 Goals + friends > diet. Can somebody link the source of this study?

Immortal island ... Go there!

40th on line globally

Taking a number of supplements …it is getting expensive..like another car payment. The NMN is $100 per month if I take two caps a day. Would I derive some benefit if I took them every other day?

David, care to comment on your ploy to seize a monopoly on NMN?

Crisper is upcoming to slice, find and attach

Like Eistein said there is no such a thing as 'time'..... People must label all things, must label others, they have to place all things in a specific box, they are obssesed with the need to control.The first question they ask is "how old are you?" They have to put all in a slot, actually most have no respect for others, nor for others need or life style.

Who else sees that David Sinclair is looking younger and younger? I suspect cosmetic procedure - kidding,but you never know. If that is not the case, he is finding the ultimate elixir- at this time.

Proactive medical, not attention when at risk

What about sea buckthorn berries amazing ...

Is there anything for cataract, if anything possible and for AMD which come with aging

It's call a heart attack gun. That is what some people are shot with to cause heart attacks.

I have hypoglycemia, low blood sugar. IT’s recommended that I eat as soon as I get up and eat every 1-2 hours. I am already 62 and look 42. Why don’t I look older if postponing eating in the morning will make you look younger?

Universal healthcare has major challenges here in Canada. I hope it’s better in Australia than here in Nova Scotia, Canada

A great book to read is called From Strength to Strength by Arthur Brooks! It really shows one how to move from one stage of your life to another and find a new purpose.

Wondering if David can recommend anything to help offset male pattern baldness other then dht inhibitors and minoxidil?

Regarding sleep do naps count as extra hours for ideal sleep or is it just the 7 to 8 hours straight

Without?

for reverse aging do they mean not just "regenerate" but even and especially "healing the body".. ? some examples like back pain, plantar fascitiis, bone marrow edema, artritis, tendinitis , often these things like many others don't get healed like they should.. will all these things get healed with this future medicine technology ? if so it would be great and a totally new view of life.. Young and healthy.. i don't think there is something better..

My mother is hypothyroidic can she takes levothyrox because she has no thyroid activity, can she take metformin or berberin? Can she even take nmn?

My opinion of the timetable: 10 years to partial rejuvination technology through partial age resets .. will give flawed age reversals that are enough to achieve longevity escape velocity. 10-20 years down the line it becomes near flawless. Maybe 30 - 40 years from now we get to have the kind of nanobot interventions which allow full body repair and restructuring that truly and fully reverses aging (and all the research that comes before it aids in mapping the genome's functioning for this purpose). 50-60 years from now we should be able to engineer our own bodies so as to remove select defects with better genetics from a universal library of genetic possibilities, doing this in the adult body and not just for new embryos. Nanobots will help remake the body in the new image of your enhanced DNA. Obviously the research needs to be strongly regulated and ethics develops as the technology becomes more reliable. At least, this is my fantasy and it hedges on the fact that global society won't collapse in the meantime.

I want it and I want it now

See mandala, sound frequencies of AUM

Such disruptive technology will face huge obstacles from pharmaceuticals and traditional medicine.

I think Dr. David Sinclair has conflict of interest with some companies, He probably he is a good scientist but, he should be clear and straight with the audience that follow innovation and new discoveries.

He himself is an example...has improved allooty

10 to 15 years to be inmortal. Im in.

BTW, big fan of the both of you!

David please PLEASE learn Dr.brugh Joy heart surgeon s healing heart energy work. Forth level of heart chakra open is divine knowing

I am starting to lose patience and hope in this longevity pill. I studied biotechnology 20 years ago and remember my proffesor saying back then, that scientists trying to elongate telomeres and stop the aging process. It is just around the corner. And here we are 20 years later with similar expirements in MICE! Honestly, with this pace it is at least 50 years away! Frustrating

If we can be Alive, then obviously we can Live Forever, we just need to find out how to do this (do not forget drinking Milk)

Dr. Sinclair refuses to debate scientists who state sirtuins are not conserved longevity genes. He should welcome the challenges if he has evidence for support. The following is one case. "Sirtuins are not conserved longevity genes" Charles Brenner Life Metabolism Volume 1, Issue 2 October 2022, Pages 122-133

Create right conditions for good health

Since 2014 till to 2023 january, i think this longevity field is standing still. I am following for 8 years and nothing noteworthy has come out. So frustrating.all these partial epigenetic reprograming of cells and tissues, damage control, senolytics, telomere lengthening etc all were hot topics then and they still are saying the same stuff after 8 years. Nothing radical has been invented. Only thing these men always say that they are working upon and trying to figure out.. and always the tangible technology is 15 years away. It was 15 years away then in 2014 and it is 15 years away in 2023. I fear that these men are clever and building their career by selling a sci fi hope . May be we are still 200 years away . Or may be we are really 10 years away. Who knows. I will wait .. what to do.. and maintain good lifestyle and eat healthy . I am disheartened to a lot of extent regarding the sluggish pace of this longevity field.

Thank you for sharing all the info about the ultra-fascinating topic of longevity! If I heard you correctly, you keep calling a forward slash (/) a backslash (\) though :)

Do have a link or the title of the long term Harvard study that was referenced at @13:00 ?