The Muscle Supplement you should be taking for your Brain.

Рет қаралды 168,292

10 ай бұрын

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REFERENCES (How to use: Copy and paste the DOI number into search engine):
[1] doi:10.1093/nutrit/nuac064
[2] doi:10.1007/s00213-005-0269-z
[3] doi:10.1523/JNEUROSCI.3113-14.2015
[4] nsuworks.nova.edu/neurosports...
[5] doi:10.1016/j.physbeh.2006.08.024
*******CRITIQUES, RULES, AND NOTES*******
Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:
Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also be aware that I receive hundreds of KZfaq comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, KZfaq auto-deletes links, so I do not see most comments with links attached.
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#creatine #brainhealth #agingbackwards

Пікірлер: 754

@Physionic 10 ай бұрын

I know where my car keys are.

@SaraUsnzsa 10 ай бұрын

That is grandpa 😂

@MarkJones-gt2qd 10 ай бұрын

Sure. But do you know where mine are?

@Pierre-Leloup 10 ай бұрын

@MarkJones-gt2qd You don't have a car 😜

@Physionic 10 ай бұрын

Mark - I haven't looked into the mind reading abilities creatine offers. :)

@stefanweilhartner4415 10 ай бұрын

great, now you just have to find your car 🙂

@brulsmurf 10 ай бұрын

content starts at @0:00

@milanpaudel9624 10 ай бұрын

thanks

@barend4285 10 ай бұрын

😂

@tara5742 10 ай бұрын

Not all heros wear capes

@donutwindy 10 ай бұрын

I watched at 0 and he only said "it's". Buy it you watch long enough, I think he mentions it at 0:01.

@yuliyahrybachova6473 10 ай бұрын

😆😆😆Funny

@Marco_My_Words 10 ай бұрын

I've never encountered a KZfaqr who gets to the point as quickly as you, without a 10-minute preamble. I'll definitely watch the whole video regardless! Thank you!

@zenlandzipline 10 ай бұрын

Yeah. I’m watching it out of respect for not stringing us along and making us FF through the video, or looking in the comments for someone to give a timestamp or the answer. Very rare these days. Plus, I’m sure I’ll learn something g here.

@sunnymountainhoneyfountain 10 ай бұрын

So true. I was ready to start skipping the unnecessary preamble and was totally caught off guard that he just said right way

@whitewolf6730 10 ай бұрын

This guy is ok, right!

@whitewolf6730 10 ай бұрын

Show off!

@Jianju69 10 ай бұрын

Ironic how it makes me want to continue watching out of pure gratitude.

@lifeofatruckerswife 2 ай бұрын

My dad has dementia....he made a lot of mistakes in his life that i firmly believe didn't help him in his elderly years. I am in no way blaming him for the state he's in....but he absolutely didn't do anything to help himself years ago He was a horrible functioning alcoholic...he held down a job, but in his off time he NEVER went without a drink. When he stopped drinking he transferred that addiction to pure sugar. He also is now a type 2 diabetic... I wish he would have taken better care of himself years ago. Now his cognitive function is failing, his sugar is somewhat controlled (it can be a challenge, he likes to sneak sugar) The reason im leaving this comment is to just let future readers know... take care of yourself while you can. What you do now will impact you later in your life. If there are ways to better your health now... don't let that slip away.

@glenntimberlake2413 29 күн бұрын

Well stated.

@1212holden 10 ай бұрын

I respect the opening to the video lmao, wish more KZfaqrs opened like that

@Physionic 10 ай бұрын

Not too conducive for growing a channel, but it fit in this context. Thanks, holden.

@supernova1976 10 ай бұрын

No wander sardines are so good for mood and memory, they are packed with creatine, Omega 3, B12, magnesium, zinc and vitamin D.

@stanleyhughes856 10 ай бұрын

Yh I’m not very educated on these things but they are also some of the best compounds for muscle growth as well but you can overdose on sardines I believe unless I’m confusing it with tuna which now I’ve said it I believe that to be true instead

@supernova1976 10 ай бұрын

@@stanleyhughes856Do you mean Overdose in heavey metals ? That's bigger fish not sardines, in fact sardines have some of the lowest heavy metals. I guess Tuna is the one.

@MrTheRalez 5 ай бұрын

@@supernova1976 yea, because sardine is fish in lower chain food. Other big fish eat them.

@flcps 4 ай бұрын

It's a young fish too @@MrTheRalez

@asparrow9876 2 ай бұрын

@@stanleyhughes856 You're confusing it with mercury poisoning, which happens when eating an EXCESSIVE amount of seafood constantly. I'm talking 80% of your diet, all fish. Also there's low mercury categories, medium, high and dangerous. For example, nobody should eat any sharks, dangerously high levels. Swordfish and tunas are high. Salmons etc are medium, then shrimp and light tuna is low. Levels vary per region cultivated or farmed, but generally that's about how it goes. You'd need to eat like 15~25 boxes of sardines daily to overdose on mercury.

@Handlethis6513 10 ай бұрын

I first started taking Creatine hcl for muscle performance, but noticed a larger cognitive gain while at work. One of the best bang for your buck supplements out there.

@hohnr2310 10 ай бұрын

It's because of DHT. It's more active form of testosterone and creatine is enhancing DHT production. I suppose if more protein is consumed.

@GeneraluStelaru 10 ай бұрын

How old are you, if you don't mind?

@JohnnytNatural 10 ай бұрын

BS supplement, you're going to develop a dependency and your brain is going to become "addicted" to it where you have to take it for the rest of your life and even then it's not a longevity supplement, just like all these low test trt takers, your body becomes dependent on them and need more and more as you get older

@bogse 10 ай бұрын

That would mean that creatine causes hair loss. There is controversy does it or doesnt it cause hair loss.@@hohnr2310

@grahamh3796 10 ай бұрын

How much did you take per day?

@ReynoldsCCR 10 ай бұрын

I am age 83 and closing in on the record as oldest player at my local tennis club. [ Only 7 years to go. ] But since turning 80 I've noticed a significant reduction in my level of play (which was never that good, even though I started at the club at age 15). To improve my speed around the court I've been trying various supplements, the most recent additions being Taurine and GlyNAC, - which may have helped a little. A few years back I tried creatine, but gave it up when I heard it only bulked up muscle size but not strength. Your report has encouraged me to try creatine again, mainly as it may improve my reaction time which can be too slow (as I watch the ball whiz by me). PS Love your analyses, but can't afford your subscription. Please keep up the public anti-aging videos.

@snave59 10 ай бұрын

I don't know where you you heard it does not increase strength,but that is 100% wrong! I used creatine back in the early 1990's when it first became available.I was a weight lifter and bodybuilder.I can tell you for a fact,it will increase size and strength of your muscles.

@nicod1361 10 ай бұрын

you are impressive ! stay focused and strong, best wishes

@JWSoul 10 ай бұрын

It increases strength by adding more water, thus allowing your muscles to go further.

@MrZoomah 9 ай бұрын

Love it. Had so many good experience with club veterans giving me knowledge. When I was 10 I would walk down every Sunday and play tennis with an 85 year old lady, who thrashed me for 12 months. She signed me up for a competition... first time against kids my age... and I couldn't lose. What she had taught me about controlling the opposition (by how effectively she controlled me on the court) made playing against kids a walk in the park. At 18 I played hockey. When our goalie got injured we looked around someone to fill in and a 72 year old from the veterans team put his hand up. He would yell, "Two steps left. You there, drop three steps." He would position everyone so well that we went from second bottom of the ladder to 3rd. When our goalie came back I took the skills he taught us and started doing the same. Ended up winning the grand final. Then in my 20s I went rock climbing. Had a Swiss 79 year old as my training partner. (he's 86 now and still climbing) One day a group of body builders came into the rock climbing gym and timed each other climbing the wall. He walked over and said, "Very impressive young man. Can I have a try?" He threw his beard over his shoulder and promptly beat their best time because rock climbing is about technique, balance, pound for pound strength and, most importantly, thinking. By the time he touches a wall he has already planned every one of his moves. The body builders were just too focused on their strength to be good rock climbers. He sat them down and coached them on their technique and sports psychology, and they came back week after week for their 'psycho ed' class. (psychology education)

@andresamplonius315 9 ай бұрын

Try creatine together with Fenugreek. Some Black Maca wouldn't hurt too.

@altkev 10 ай бұрын

There is nothing more awesome than the answer to a click bait title being given in the first 5 seconds. The KZfaq hero we deserve.

@bokwanable 10 ай бұрын

66 year old male who suffered chronic stress during Covid insanity, locked out off Australia for two years, was very aware of the cognitive decline and BP issues that manifested for two years. Tried creatine 3 grams daily, after a week I had a moment of clarity and have been on the improve since, no dementia and cognitive function return has been quite noticeable.

@caen-un9cw 9 ай бұрын

Have you done any excercise with the creatine that you weren't doing before?

@melissaholdren1738 10 ай бұрын

I'm actually prescribed creatine by an MD to treat "chronic fatigue syndrome" (a term i loathe, being a nurse myself). In addition to high dose Coenzyme Q10. This research team's testing shows some indirect evidence of mitochondrial dysfunction. And let me tell you, the difference I feel if I've forgotten that creatine too many days in a row... It's made me a believer even though i hate the chalky, awful stuff

@allanlowe3430 10 ай бұрын

First time listener, You have a talent for presenting scientific information. Thanks for this analysis.

@Physionic 10 ай бұрын

Thank you, Allan.

@gdok6088 10 ай бұрын

I'm looking forward to the day when Nic is a Professor with his own lab and department at a University, with PhD students working under his supervision, adding great and innovative research to fill in some of the many gaps in our knowledge.

@gregkocher5352 Ай бұрын

Started keto in early 2023 and slowly have added other supplements over the months. I'm just starting creatine now. I've gone from 270lb to 225 lb, allmy labs have been very good. I hope to reach 205 this year. I'm 69 yo. Your videos have always benefited me. TY.

@a_bar8579 10 ай бұрын

This man is not only scientifically intelligent but also humorous 😀

@Kaizen747 9 ай бұрын

Indeed

@VeinyPathwayPassion Ай бұрын

Absolutely

@user-sn2cx7fb5w 9 ай бұрын

0:01 GOAT

@davisterrel 10 ай бұрын

I love how you went straight to the point! I stayed all the video just for that and the useful information!

@gabriellew6467 10 ай бұрын

Imparting knowledge in an entertaining way is rare - you certainly got the knack!

@thinkfromabove 2 ай бұрын

Whoa. Straight to the point. Even before the one second mark. Every KZfaqr needs to take lessons from you. Well done sir. Liked and subbed.

@banksiaspinulosa7442 10 ай бұрын

I enjoy your speculation. I think you connect dots very quickly and its exciting to hear what isn't necessarily PROVEN but has potenial/is possible.

@ImEmpTy295 10 ай бұрын

Stumbled upon this channel from youtube recommmendations. And i must say, this channel is highly underrated.

@thirdworldperspective2409 10 ай бұрын

Hey nick, nice to see you’ve improved greatly in your communication, you are much more at ease in you latest videos. Been here since the start Now look at you, 100k subs, I knew it was bound to happen. Congratulations brother you deserve it. Richard. Keep up the great work.

@Sundara229 10 ай бұрын

Straight to the point. Big appreciation for this channel.

@smallbluemachine 10 ай бұрын

Thanks for not burying that 10 minutes into a video and prefacing it with NordVPN sponsorship. Sometimes, people deserve, to have their faith, rewarded.

@abacate_com_limao_ 10 ай бұрын

I love the humor of this channel, specially cuz at the same time you can feel science been taken deadly serious 🤟

@andysharpe814 10 ай бұрын

Kept my pinky promise and even though a lot of it goes over my head it’s still very interesting. Thank you keep doing what your doing

@stevescruby1343 8 ай бұрын

I’m showing my folks this video. Thanks Phys!!

@Mikangelovillalopez 10 ай бұрын

I respect ytbers who say the answer right at the front so much I subscribed and watched the whole thing. 👍🏼

@ambrsanford3703 10 ай бұрын

You certainly know how to explain what you know effectively. Thanks for the competence, clarity and humility to outline what you may be less certain of.

@jmc8076 10 ай бұрын

That’s the professor in him. His other job. 😉

@adityasangore5323 10 ай бұрын

You're a gem Physionic.

@k4dr0n2 10 ай бұрын

I will watch till the end because you lowered my anxiety for the rest of the day by disclosing the information

@pianogal853 10 ай бұрын

Thank you for your content. At 62 im doing a young person's job and really need to keep up with my health.

@mxrc179 9 ай бұрын

I appreciate the rigor and integrity of the presentations. Being clear about your hypotheses versus the results of your research makes your presentations many times more valuable and reliable than other presenters---by far. Further, your explanations of the statistical errors and fallacies reveal much about the problems with many meta studies and other studies. THANK YOU for modeling critical thinking at its best.

@Muldoon111 5 күн бұрын

I not only kept my pinky promise, but I subscribed as well. Excellent video.

@Physionic 5 күн бұрын

Thanks :)

@valentinkrajzelman4649 9 ай бұрын

not a second of preamble i love it.

@matthewsalomone3800 5 ай бұрын

I think I can simplify this for anyone who's curious. I'm 57 years old. Been dealing with brain fog and extreme low energy. I started taking testosterone injections and to some extent, It did help but when I added three grams of creatine a few times a week in my coffee, it was like someone injected, jet fuel and me. I had much more energy. I was able to do my work more efficiently. I was laughing and excited again about life. Just try it. It'll either help you and make you feel great or it won't.

@TikiTDO 10 ай бұрын

Thanks for starting the video with the actual information. Have a full premium view for that.

@jackbuaer3828 10 ай бұрын

I kept my pinkie promise and commented for the algorithm. Non-Creatine User Here. (I have tried it in the past, did not care for it.) I have enough muscle mass for now. I have been consistently 190, 6'2' and relatively low bodyfat for the last 15 years. I don't really need more muscle for health reasons. I am in my mid 50s and have lost some strength, but I could still do more than 15 consecutive pullups. I do less weight lifting these days, and your previous video further encouraged me to keep my weight lifting under 100 minutes per week. I do more cardio / sports, so I have not reduced exercise time. If anything, I increased exercise time. When I look at studies, it appears to me that both resistance training and cardio seem to help to optimize longevity, but cardio seems to give one more bang for the buck, so that's where I prioritize. Much of my cardio is agility , eye hand coordination drills and that's fun for me. Weight lifting is less enjoyable. My guess is the "fun factor" plays into longevity, but that's just a guess.

@nancykowalczyk2070 7 ай бұрын

Yes, I pinky promise and I’m good with my word! Love your info and dry wit!

@jamestaylor9258 2 күн бұрын

Thanks for starting with it and then explaining.

@olib4936 10 ай бұрын

Congrats dude ! Most youtubers try to get attention with a title like yours and enroll the information in the midst of the video, and in comparision, your entrance is simply epic ! It`s Creatine !

@Darwin973 10 ай бұрын

Great channel. Scientific information presented concisely and with great clarity.

@melorsomething1006 10 ай бұрын

I’m a younger dropout viewer (20) and I just wanna say I always appreciate your delivery. Even tho I have no medical experience, I feel like I can still grasp the broader information you’re giving us. This made me wanna start up my creatine dosing again haha.

@Physionic 10 ай бұрын

Thanks for watching, and the kind words.

@_negentropy_ 7 ай бұрын

I so appreciate your analyses, and always grateful for the help in research literacy.

@jamesmoore5630 10 ай бұрын

I just spent $233.00, (Sales!!!) At GNC, (Not a plug.) and they were out of "Creatine" and a couple of other things like "Folate." I have GABA already. I have a kidney issue, probably kidney disease, and I am treating that now. I am 62, no brain fog but, I was getting brain fog before I started keeping, Vitamins, Minerals, and supplements including all the amino acids in my refrigerator. I just recovered from a broken Tibia and Fibula and I have 3 more weeks of P.T. My surgeon though it would take 6 more months for me to recover, but, I heal fast and I have Autism and a 98% recall, so anatomy and physiology is still fresh in my mind. Thank you for covering this topic, as I will pass it by my doctor for approval. Thanks, Brother James Kendall Moore OSB OFS OSC ✝️

@TheKitty1952 10 ай бұрын

I'm 71 and have started taking a weekly dance/exercise class (along with cardio swimming, yoga, and walking). The dance class relies on memory, movement and endurance. I will be adding creatine to my supplements for hopes of improvement in meant agility.

@someball. 9 ай бұрын

did it help?

@glenntimberlake2413 29 күн бұрын

Excellent plan.!

@lolwtfbbq111 9 ай бұрын

Thank you for saying it immediately. As a thank you I shall watch the full video ❤

@Hashass1n 9 ай бұрын

Thanks for getting to the point. Watched the whole thing

@Angel-wo8gv 10 ай бұрын

Thank you for disclosing the supplement at the very beginning, very few youtubers do that. Of course i stayed for the whole vid :)

@josephtaylor6285 10 ай бұрын

🧐Once again Future Doctor Verhoeven, you’ve outdone yourself! I’m 64 and respond well to 5 to 10 grams. In addition to my brain improving on a number of levels, I also note that my legs are more powerful when navigating the streets of NYC and I am also more positive in my outlook. I’ve passed your videos around to a number of my friends. Your breakdowns of these studies are invaluable. Keep up the good work friend.

@grahamastor4194 10 ай бұрын

If you don't mind me asking which brand do you use? I'm just 67 and need some help with brain clarity. Thanks.

@neferiusnexus 10 ай бұрын

make sure you're also taking some L-Cysteine there, as it eats into your stores and having less Cysteine accelerates aging (your body needs it to make Glutathione, the most powerful antioxidant and the molecule which also cleans up heavy metals from the body)

@josephtaylor6285 10 ай бұрын

I use micronized creatine powder from Optimum Nutrition., which is Creatine monohydrate.

@josephtaylor6285 10 ай бұрын

@@grahamastor4194 Optimum Nutrition’s Creatine Monohydrate. It days micronized creatine on the front of the container

@pablodelgado1746 10 ай бұрын

Thanks a lot for sharing your knowledge in a very comprehensive way! 🙏🏽🙌🏽🤓

@consciouscactus 10 ай бұрын

Always love your in-depthness in your videos

@Physionic 10 ай бұрын

Thanks!

@skob1014 10 ай бұрын

Only thank you for all your great videos

@Antique803 10 ай бұрын

Being 70 and seeing lots of people becoming forgetful and entering dementia. I will do anything to forgo that situation. I stay busy tackling various mental challenges of the constructive type…gardening, mechanic work, carpentry, food preserving, auto restoration, electrical problems…I do it all not willing to hire a single sole to perform task I can do. I think I’ll try creatine and see if it helps and how it helps.

@orientalbean 15 күн бұрын

Amazing man, finally a to the point youtuber that has an understanding of statistical significance so i dont have to read research papers

@thorbjrnjohnsen4859 10 ай бұрын

Best start on a video!

@joehelland1635 10 ай бұрын

Thumbs up and sub for not doing a clickbait and laying out the videos conclusions in a nice simple opener.

@serifir8663 10 ай бұрын

You honestly got my subscription for answering it right away instead of waiting for the last 5 sec of the video. Much appreciated 👍

@kw7796 9 ай бұрын

Great info. Love your quirky humor....makes learning fun.

@curigger4486 9 ай бұрын

your super sympathic, love your content!

@maddognl 10 ай бұрын

Couldn't it be just a side effect from the increased muscle performance? It may lead to more physical activity for the elderly, which in return could improve overall health and indirectly brain function as well (Better bloodflow, more daylight + fresh air, ect.ect.) Just a random thought bubble, based on nothing but well....the bubble.

@TheSpecialJ11 5 ай бұрын

Creatine and its relationship with methylation means it definitely isn't just the increased exercise performance. Tons of brain functions rely on methylation, and supplementing creatine makes more resources available for brain processes even if it itself doesn't directly affect the brain. Someone with fine methylation status might not see any benefit though.

@christinamilioni6325 10 ай бұрын

Thank you for the great content as always! Greetings from Greece 😊

@Physionic 10 ай бұрын

Thanks, Christina.

@JamesKing2understandinglife 7 ай бұрын

Thank you. I really like your commentary and style of discussion with me. I am a new subscriber. Thank you for your study break downs.

@pwesiti 10 ай бұрын

I really appreciate your delivery in this. I love the campy attitude. 😂

@escapegulag4317 5 ай бұрын

got to the point immediately. I respect that. Imma sub just as fast

@turnerc23 3 ай бұрын

Best video I've watched all day, right from the start!

@azdhan 7 ай бұрын

Love your videos. Many thanks for sharing!

@ijimstopit 10 ай бұрын

Well done! Entertaining and detailed information.

@keanuwalls7949 9 ай бұрын

Oh you actually used science. I did not expect that. Subscribed!

@ReleaseMyKrakken 9 ай бұрын

Its creatine. I subbed just based on that. No preamble, no rant, no me having to search. Bravo.

@machawley 10 ай бұрын

Nikolas, I love the scope and depth of your analysis along with your laid back humorful approach to coping with the data. Regarding Creatine, I believe the conversation would be more robust if you included precursors for NAD+ and ATP as well as 'soot quenchers' for ROS. I'm thinking Niacin (NMN, NR), Ca-AKG, CoQ10h, B12, Folate, Creatine, etc for the first and NAC, Glycine, Vit C, Vit E, etc for the second. The Kreb's Cycle is fundamental to all life. We can address it as a complete package.

@RealJonzuk 10 ай бұрын

i take a small dose of 2.5g of creatine a day and feel amazing

Ай бұрын

Subbed. Thank you.

@shulehr 10 ай бұрын

you got me by surprise with that intro XD, im dying

@akamartinez5308 22 күн бұрын

Please just like this video because he actually goes to to point right away and has good content !

@SelfAugment 10 ай бұрын

So pleased to see Nic's channel growing quickly. I think he's become my favourite source for health information on KZfaq. Watch your back Huberman!

@Physionic 10 ай бұрын

Thanks, SA :)

@SelfAugment 10 ай бұрын

@@Physionic keep up the great work. You're a star!

@catmaclaggan 10 ай бұрын

Love your videos. Hello from Spain!

@Physionic 10 ай бұрын

Hello there!

@Andrii87 8 ай бұрын

To the point, in first 10 seconds!!! Great!!!

@FarranLee 9 ай бұрын

30 here, my cognitive function is currently pretty much fine but hasn't been great for the last couple of years. I've been taking B12 regularly, which seems to be helping, but it's hard to be sure. I haven't been diagnosed but a lot of things suggest that I have inattentive ADHD. I started using creatine a few months ago when I finally pulled my finger out and joined the gym and started jiu-jitsu training, because I noticed that my quick muscle response was not very quick, and I fatigued easily. Well I found that creatine helped for sure, but I also noticed a cognitive change. I cannot for a moment claim that my experience is at all scientific in methodology, but it did seem like the differences correlated with commencing creatine supplementation. Thanks for this video! Great presentation and delivery.

@mavr1215 10 ай бұрын

Excellent explanation 👍 very entertaining too - good sense of humour 😊

@jackiemansfield8325 Ай бұрын

I was always trying to remember a long prayer that I knew by heart since child in another idiom(I’m 65 now), but never could. Just started taking creatine, and, last night in bed, tried to say the prayer again and could say the whole thing correctly without any stress.

@tinayoga8844 10 ай бұрын

When I was 21 I lost my job and qualified for Unemployment Insurance (Canada). I had to fill out a card monthly in order to continue receiving UI. I was took a one year college course that allowed me to keep receiving UI for a year. Because I had to fill out the card every month it imprinted my Social Insurance Number in my brain. I'm 63 years old now and can easily recall my 9 digit SIN number. Where my Keys are sometimes becomes an issue. And my glasses, well I have many pairs so when I can't find the last pair I was using I have backup options. I will have to look into Creatine. If I remember it.

@IvanSKMK 10 ай бұрын

Jinx. I said it as the video started. Love your humor

@MispelledOnPurpose 10 ай бұрын

I gave you thumbs up right away for revealing the supplement right away.

@damovicious 2 ай бұрын

Deep appreciation

@kristerpresty8033 10 ай бұрын

Giving the answer straight away, that really got me! xD

@SigzTT1 10 ай бұрын

Damn, i saw the answer and skipped the video. But then i felt guilty, the hero that did what we always asked how could i betrayed him like this. Returned, liked, watched, subbed and commented! Appreciated the anti algo approach!

@Physionic 10 ай бұрын

Haha, I appreciate the dedication.

@mikeash7428 2 ай бұрын

I don't think I've found a youtube performer i appreciate the humor and ability to think so much as this you. I'm not hand gestured into paying attention as much as intelligently eyebrowed into it. In your massive research on creatine did you come across possible prostate cancer correlations with its use? I want to use it but have precancerous prostate status.

@Jton195 9 ай бұрын

Getting to the point in 5 seconds? Instant sub.

@larsnystrom6698 10 ай бұрын

Nice work! I also like the fact that creatinephosphate doesn't just acts a a buffer for ATP. It also move much faster than ATP because it's much smaller. So, it's much more effective at fetching energy from the mitocondria than ATP itself. I supplement with 4 or 5 g of creatine.

@user-bn5pq7bh5g 10 ай бұрын

It is new info to me. And the fact he wrote a book in young age.

@EduardQualls 10 ай бұрын

Extending on your presentation of ATP => ADP. When needed (during periods of greater energy needs) ATP can also be further 'degraded' to *_adenosine monophosphate,_* "AMP." At this point, stressed cells will produce a protein, *_AMP-activated protein kinase,_* "AMPK," which incites mitochondria to undergo growth and/or replication, to increase ATP-production-capacity. A major problem is that (1) AMPK has an "exposed" glycine and (2) one of the metabolites of fructose, _polyol,_ binds to that glycine and renders the AMPK biologically inactive, destroying its ability to incite the needed mitochondrial increase. This is highly suggestive of how fructose causes cells to fail at task and at self-maintenance, to "wear out" and die, thus causing neuronal and brain-cell death, in particular. *Fructose => Alzheimer's/dementia by suppression of ATP production, so **_creatine could be particularly important in helping avoid the worst of this situation._* This is particularly important in how the brain will autonomously create fructose in response to higher glucose or fructose levels outside the blood-brain barrier, to maintain balanced osmotic pressure. The accumulation of fructose-damage over the years may explain creatine's greater impact on older individuals.

@joylugo4979 10 ай бұрын

interesting

@MyrKnof 10 ай бұрын

@@joylugo4979 like, VERY interesting.. Fructose is so SO bad for you as far as i can gather. Especially in refined form.

@mikafoxx2717 10 ай бұрын

@@MyrKnofI think a health individual can probably handle some fruit off the tree or bush when in season, because it's periodic and lower in dose and cellulose delays its release so the liver can process it more thoroughly.. drinking refined honey, sugar, high fructose corn syrup, all that is awful for your liver and blood fructose is more glycating than glucose or galactose, yet isn't measures in any of the glycation measures like A1c.

@rgeyser1520 10 ай бұрын

Thank you for sharing this. Wouldn’t supplementing with AMPK or AMPK-containing foods spur growth/replication? Have there been any studies?

@baconinvader 10 ай бұрын

interesting, where can we learn more?

@StKrane 10 ай бұрын

I work a lot of nights. My brain can use the support 💪🏻 Thank you!

@dorsia6938 10 ай бұрын

Great video, subbed.

@reskun 9 ай бұрын

omg finally, thank you for just saying it outright, liked and watching the rest just for that alone

@occasionalstreamsearcher100 10 ай бұрын

You are cool bro. Nice content, good form. Cheers from New Zealand.

@kelbarnes216 10 ай бұрын

You're legit man. Subscribed!

@Physionic 10 ай бұрын

Thank you!

@brianbean8018 10 ай бұрын

I truly appreciate your approach and the time you put into these videos so, thank you Nicholas. I always have so many questions for you. Here's one(this is my first post to you): Are you currently working on your own research that could 'fill in' the holes of information/data showing more benefits of creatine? My apologies if this question has been previously answered and I missed it.

@cowboyglizzy1883 9 ай бұрын

I watched the entire vid and subbed broski

@Physionic 9 ай бұрын

Thanks!

@535Salomon 10 ай бұрын

When I started taking creatine and after taking it for a really long time I felt improvement on my fine motor skills.

@Cld1512 9 ай бұрын

I don't know who you are, or want you want, but I love you for this video!

@clintbrock7697 5 ай бұрын

I always know my SSN and where my car keys are, but I ALWAYS use the car honk feature of my car fob to find where I parked my car a few minutes earlier! Which reminds me, for that to work and since I need to get closer to my car than I used to, I need a fresh battery in the fob!