I think the one that Sheldon did to Leonard with the sweater is pretty cruel.

That chemical reaction on Kripke and the staff was priceless

Howard's 'Sheldon' costume is still by far one of the most hilarious moments of the series.

"I tried to scare an Indian with a snake" lmao🤣

1:17

You left out one of the best pranks. The one where they showed Sheldon a card trick where Howard guess what card you're holding, challenged him to figure it out, only to reveal at the end they'd been tricking him and whoever does the trick with Howard just agrees with whatever he guesses, right or wrong.

"How could I be so STUUUUUUUUUUUUUUUUUUU!!!!"🤣🤣🤣🤣🤣🤣

2:21

Howard playing Sheldon shows just how truly amazing an actor Simon Helberg really is.

That sweater thing was one of the worst thing Sheldon has done to Leonard, totally get it when Leonard slap him so hard after his nobel win.

Nothing beats I mean NO PRANK in the entire show beats howard cosplaying as Sheldon 😂

10:38

9:56

My favorite one was either when Howard dressed up as Sheldon or when Kripke put helium gas in Sheldon's office.

Leanord's reaction at

8:13

GREAT video to post on April Fool's day!

These pranks are hilarious 😂😂😂😂😂

9:10

Is Barry’s prank the reason they didn’t have enough helium for their experiment later on