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Osteoporosis is a risk factor for bone fracture much as high blood pressure is a risk factor for heart disease. Prolia helps prevent bone loss and actually results in some new bone formation. With 2 injections under the skin’s surface each year, it requires minimal hassle. The so-called FRAX score, available online, rates the likelihood of a bone fracture and assists in determining an individual’s need for therapy. Unfortunately it may overestimate the need for medical intervention.