Now that's one dedicated Dr.

Someone that uses himself for study is someone to be remembered with all pride and love.

This doctor literally infected himself to prove his point. That's so metal.

I suffered from ulcers for years and in the early 1990s by doctor, having tried everything short of surgery, told me about this theory. He proscribed a high dose antibiotic and large quantities of bismuth. After 2 weeks I was ulcer free for the first time since 1983. Not a problem since.

Kudos to both doctors. Even they've been laughed on...they still continue their studies. They have GUTS.

*This dude drank contents extracted from his patients' stomach?* *You can't get any crazier than that.*

“he swallowed a cloudy broth of bacteria collected from the stomach of one of his patients” NOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOoh my goddddddddddddd i could never

Me: Having ulcers Parents: "Its all because of that damn phone"

You hear that mom? I am watching something educational. _increases volume_ . You hear that mom? YA HEAR?

These animations were quite amazing! I think you should continue with this art style.

I almost died at 17 after having multiple ulcers since the age of 11. Many doctors I saw did not believe that I had ulcers, they thought it was caused by emotions. It wasnt until after they did scopes that they realized I was not just "emotional".

I almost threw up when doc drank his patients bacteria. That's another level of dedication to your field.

loved those awkwardly silent solid couple seconds of nothing but "fish floating in acid"

I don't understand why anyone would thumb this video down. I wonder if those people could be part of the Acid Mafia. haha

Dr. Marshall was simply one of the best doctors who ever lived. Hats off to him. A great person who took such a risk on himself for his patients.

I took these antibiotics for my stomach ulcer. A two week course fixed what had been months of crippling pain. My fault for not seeing about it earlier. Either way the work done by these guys deserve the highest praise. I can only imagine the millions of lives made better for it. Well done!!!!!

Woah the science, the animation and the narration so perfect. And to give so much information in 5min without being boring is something which all teachers around the globe must aspire to.

I demand my stomach to build a wall and keep this bacteria out

To all doctors who are studying STDs, please don't

I had h-pylori twice in my lifetime (am only 27 years old) and it’s sooo painful 😣 I also had an ulcer once due to h-pylori and trust me it’s not that fun. However, am forever thankful to this doctor’s contribution to science 🙏 without it I might’ve had to go through surgery 🙃

That doc is really caring... And trust is guts like mad. Because make yourself sick to find answers is mad. Thank you for beeing a mad scientist.

I dunno about ulcer, but the worst stomach pains I’ve experimented were when I was also experiencing psychological stress. It can’t be just a coincidence.

The moment I read the title of this video I was hoping that it would talk about H. Pylori, and I felt vindicated when it did. I was diagnosed with H. Pylori in high school. For years before that I have chronic stomach pain and nausea, but every time I went to my doctor she said it was because of stress and anxiety. I was surprised when a new doctor told me my symptoms may be caused by a bacteria that eats away at your stomach lining, allowing acid to hurt your stomach. I took antibiotics that killed the bacteria, and my stomach slowly healed. I still have stomach issues, but they’re much less frequent. I do wish this video described *how* H. Pylori causes stomach ulcers. And that it didn’t dismiss that stress and anxiety do cause stomach pain and nausea. Stomach issues are a stress response, and prolonged toxic stress weakens your immune system and allows bacteria to hurt your body. But it is a huge problem that many symptoms are dismissed by doctors as being due to stress, when they could be caused by a number of physical problems.

Barry Marshall, an Australian Doctor. Shall not be forgotten.

I can’t stand it when people say spicy food causes ulcers

I remember my late grandfather who died in the 90s, the poor man suffered from chronic ulcers. I remember asking what caused them, and family members would say ‘we don’t know, doctors say anything can cause uclers, like too much acid, but there’s no cure and no known cause’. I’m so glad we finally found the culprit!

Quality, data driven education. Nice work. You have the physicians spirit

1:37 Me and my best friend after a couple of drinks on a night-out

I need to show this to my Doctor. and maybe ask him where did he got his education

Tapeworms are also a pain. They live in your stomach (rent free) and get most of your food and drink (also for free). Damn tapeworms.

Had stomach ulcer when I was 5. I remember a lot of childhood memories and it’s the memory I don’t want to remember but do. It’s one of the worst pains I’ve ever had in my life. Had to stop school for 2 months because of it and my parents were so worried! It’s one of those pains that’s up there along with kidney stones.

Hi I am a doctor and I had suffered from gastritis due to h.pylori infection during my college days,and had taken the triple regimen of antibiotics which took care of it....never knew the history about it.Thanks guys and super cool animation..😂👏🏽

I had gastritis a few years ago--actually, about the same time as this video was made. That was the worst month of my life. Not because I was in pain, since the pain went away rather quickly after I started taking antibiotics, but because when you have an ulcer, there is so much food that you can't eat. I ended up just not eating as much because I couldn't eat anything tasty, and my options were so limited that I was getting sick of unseasoned chicken and rice and apples.

My ulcers were a result of taking antibiotics before having oral surgery and it wiped out all my good gut bacteria. If you have to take antibiotics at all, especially the ones that clear out your gut, load up on probiotics!!!

I was a heavy drinker and had stomach pain at night after dinner and lasted from 10pm till 9-10 in clock in the morning. I fixed my diet and ate around 4 , took probiotics and quit alcohol all together. It took me a good 6 months for it to disappear all together. I slowly saw the pain come back less severe than before and eventually but went away. I haven’t had stomach pain for a year and alcohol is not worth that pain Al all.

Whoever this doctor is, is a hero

You should have a disclaimer that you are not medical professionals and to consult a doctor if you have any reoccurring stomach pains.

This art style & animation was brilliant. I hope there's more like this one in the future.

Thanks to the work of Dr Marshall, I got a diagnosis of H. Pylori and after so much suffering (that started as a child)… I recovered… but it wasn’t an easy ride, so I admire what he put himself through for many others well being. May God bless you ♥️🙏🏽

It's so crazy to think so many folks out there have gone through the same thing! I've suffered from peptic ulcers due to (what doctors believe is) ulcerative colitis since I was about eleven or twelve. It took them nearly five years (and four endoscopies/biopsies) to pinpoint that it was a massive bloody ulcer in my duodenum that was causing me so much pain -- of course, after having had my (perfectly healthy) gallbladder and appendix removed because there was "no reason someone this young should be in this much pain". Nearly a decade later, even though several rounds of PPI's, antacids, antibiotics and strict dieting, I still continue to suffer from chronic pain that ranges from manageable to needing hospitalisation for days on end, but that won't stop me from finding a cure! Kudos to this incredible pair of doctors, their work should be published worldwide!

I had stomach ulcer about 17 years ago, and my doctor keep prescribed me with stomach acid suppression whenever symptoms reappearing (every 6 months or so), and I had that going for years. Until one day I meet a new doctor, she suggested it might be a bacterial infection and wanted me to do a test, sure enough, the test showed positive for bacterial infection, then I got the antibiotics, after a week I was fully cured, haven't had the ulcers ever since. Thanks to this video, I now know who I should thank the most 🙏

Wow I’m over here with stomach pain because of my stomach ulcers and this video pops up on my feed 😂😂😂😂😂😂

"Fun fact": Stress may be related to ulcers because it usually affects our immunologic system and a inflamatory response. With a weaker immune defense, bacterias (and other organisms) that are usually "harmless" or easily defeated can turn out as a big problem. Of course, it doesn't mean that if you arent stressed you will not get ulcers, or if you are stressed you will get ulcers, but stress may be related to that problem.

I lost my father to stomach cancer 1996 which had been preceded by years of ulcers. We thought it was because of stress and spicy food. If only we knew What we know now 😔 rest in peace Dad

The guy had guts to do that

Great video but your conclusions weren’t very specific.

Einstein once said “No amount of experimentation can ever prove me right; a single experiment can prove me wrong.”

Barry Marshall is such a legend. He totally deserves his Nobel prize.

Wow that was so informative... Can't believe the stress and food notions are still so prevalent. I had an ulcer for the first time recently and now I understand the correlation between the first time trying Tylenol as well.

I still think that ulcers can be caused by stress due to the fact that stress can effect our immune systems and can allow bad bacteria into our bodies.

What a HERO. I read an article about Barry Marshall a long time ago (probably around when he won the Nobel) but it was verrry complicated, but I was also really young. All I took away from it was that he was a hero and stress does NOT cause ulcers. When I would tell people the stress cause was a myth, they'd be like "Then what does?!" I wasn't able to fully explain it because the way i learned about it was always too complex....until now! I'm glad I can honor Marshall's work and can help dispel this rumor in my everyday life. :)

Doctors are nature's treasure

Yes! Finally my Mom can listen to me for once because she has all of these problems (smoking, joint pain, etc) she needs to test if she has H. Pylori in her stomach. She had this ulcer for 15 years. Doctors told her to live with it. Thank you Ted-Ed!

Never seen such dedicated, auspicious and powerful doctor

I suffer from Pulmonary Hypertension. There are three different studies that show that my condition may be caused by gut bateria. So this concept is not too far off base. Now I'm trying to find those that are studying this complex condition in the hopes that they will find a cure for my condition before I die

The plane drawing at 28 seconds is the real hero of this video

Stress is still one of the main causes of ulcers - by weakening the immune system and allowing the H. pylori to multiply & get past the stomach's defenses. We learned this in Microbiology. Also, ask anyone who gets ulcers from stress.

I heard about it on the radio on my way to school when I was a little girl in the early ‘90s. What’s shocking is that people still think ulcers are caused by stress, food and excess acid *30 YEARS* later.

In my country, people believe that ulcer is caused by eating only small amount of food, so if I'm on diet, they will tell me I might get ulcer if I don't more food.

I will for sure remember this doctor he is an asset to humanity

58 seconds after the vid released! Wow...having said that out loud, I’m ready to make some life changes lol

I’ve had Gastritis twice, and it was extremely painful!

Yes. This is exactly what I had, it was causing a plethora of problems. Probiotics gave instant but short-term relief, but once I asked my Dr to test for helicobactor pylori, got the antibiotics to kill it, and healed myself with bone broth, my quality of life changed drastically!

I remember when this was happening. The treatment for ulcers at the time was directed at methods for limiting anxiety and avoiding robust foods. That the treatment didn't cure the condition was telling.

Excellent video, and good explanation about ulcers occur. One thing to know, your normal flora controls a lot of your illness and keep you healthy. Anything that affects it including taking antibiotics, stressors, illness, infection will alter the GI gut Flora. This alteration of the gut Flora allows for bad bacteria/ yeast to proliferate and cause disease

I like the pointy finger reaction by the animated doctors...hilarious

I'm addicted to this voice

- So how did you make your famous discovery? - Idk, I just had a gut feeling, man

Had 2 bleeding ulcers that were right on an artery earlier this year that required 2 emergency surgeries and was negative for H pilory. Turns out my great grandfather died from bleeding ulcers, my grandfather had ulcers and then I had these ulcers at the same age. While this is completely anecdotal it shows a genetic predisposition for my family and was able to give my doctors a look at a possibility of what otherwise seemed unheard of for my age.

Dr. Marshall: "one small price to pay for salvation" Helicobacter pylori: am I a joke to you?

Dr Marshall was such a hero. He deserved the Nobel Prize, even more.

Super informative, well organized script with awesome animation! Great job keep it up!

May I suggest that you do an episode talking about the way water gets in, circles around, and exits your body please? It seems interesting. Thanks!

A true hero who made millions of lives better!

As a sufferer for a couple of decades, the course of three different antibiotics for ten days gave me an utterly new lease of life. Nowadays I can eat hot food, greasy food, spicy food, get stressed, take booze and I'm fine, whereas before these contributing factors only worsened my condition. I take my hat off to this doctor for changing my life for the better. The source of the bacteria? People not washing their hands, after using the toiiet. It's that simple It doesn't have to originate with you. Others, preparing food or drink, even passing you a glass, plate, cutllery, etc, can be the start of the nightmare. I've advised many folk, since being cured about three decades ago, to consider the antibiotic treatment, before giving any serious thought to surgery, which still appears to be a standard option for many. If you aren't one of the 1% suffering from excessive hydrochloric acid why put yourself through decades of misery? Hope my own experience helps others in the same situation I was back then.

I love Ted Ed it's my favorite channel

Tbh it is the HCl that damages the mucosa of the stomach, leading to the ulcer. H pylori just messes with the stomach's pH detection so gastric juice secretions aren't turned off. That's why you prescribe triple therapy: two antibiotics and a proton pump inhibitor to inhibit gastric juice secretion. Also, H pylori is a common cause of *duodenal* ulcers (firstmost section of the small intestine). Gastric ulcers are less likely to be caused by H pylori alone; it is usually a combination of H pylori infection AND overuse of a class of painkiller called non-steroidal antiflammatories, such as aspirin and ibuprofen. With gastric ulcers, the infection needs to be all over the stomach but for duodenal ulcers only in the bottom-most region, closest to the duodenum (called the pylorus). The stomach-wide infection combined with inflammation (exacerbated by NSAID overuse, which inhibits prostaglandin as mentioned as a protective mechanism in the video) leads to gastric ulcers. Interestingly, if you have a duodenal ulcer, you are protected from gastric cancer, but more likely to get oesophageal cancer after treatment. Gastric ulcers can lead to gastric cancer and need to be closely monitored.

I was having severe stomach pains and finally found a doctor to do an endoscopy (camera down my throat) and found an ulcer-and removed it. He diagnosed me with h-pylori. I think it’s pretty contagious cause eventually my partner had a stomach ulcer months later but not sure if she was diagnosed with having h-pylori but her symptoms sounds exactly like mine. We’re both fine now but those stomach pains are no joke. I wouldn’t wish that on anyone.

Y’all hear about that one guy who only had a few weeks to live because of all the stomach ulcers he had, (he was a businessman, so he was always stressed). He asked the doctors to have him take a trip to the sea even though he was so sick because he was gonna die anyway. He has never been happier in his life, he smoked cigars, drank alcohol, and ate foods that were impossible for him to eat before. Stress is a big factor guys.

And my BIOLOGY professor said that not eating breakfast causes stomach ulcers...

My long time misconception got clear today. Thank you, Ted Ed team.

I am happy to learn that Dr Barry Marshall is still alive as of today currently at 70 yrs old

I love hearing about scientists with that kind of passion

Literally just finished treatment for H. Pylori two days ago. It's actually very common but not commonly tested for unless you're having stomach surgery.

two words for our science (specifically medical) ... fascinating yet incomplete... as Albert Einstein said - Mystery is beautiful! (as motivation). The one who is mad enough to be fascinated to solve this mystery at any coast is true scientist. Kudos to all of them!

H.pylori has also been implicated in most of my ailments. Mastic resin from Chios is a natural treatment for H.Pylori and I've found also helps gingivitis...

1:40 I like the way the guys that laughed at him have their eyes closed in shame😂

Kudos to the doctor!

I talked about ulcer yesterday on the phone with my mother on Facebook Messenger and here I am recommended a 2017 Ulcer video on 2019 by KZfaq. WTF.

In November of 2020 I was admitted into the Hospital, a few days later the doctors came into the room and said I'm diagnosed with ulcerative colItis. A long-term disease that's never going away, it goes away for a few years and later on in the future comes back. It causes severe stomach pain and diarrhea loose stools and internal bleeding. I stopped consuming dairy products and I feel a lot better, my stomach doesn't hurt and I don't have to keep going to the washroom. I've been Vegan since December 8th 2020 I never looked back, it's the best decision I've made.

My stomach perforated 4 years ago and it was caused by ulcers caused by H. Pylori. It was one of the worst pain I have ever felt in my life.

Patient: has symptoms Doctor: ingests bacteria from patient's stomach Doctor: has same bacteria now and same symptoms Doctor: *surprised Pikachu face*

Woah I just so happen to have a bad stomach ache

Stress ulcers are real and I most certainly get them during times of extreme upset...

2 empathic doctors vs dozens of careless doctors.. That is true today

I had stomach ulcers first at age four! Was plagued with them throughout childhood and until age 23! Since my twenties my digestive problems have only been intestinal! Then after hitting age 45 I seemed to have become pretty immune to pylori problems! So some physical problems get better with age! It was finally good to learn about the cause behind ulcers!

The story of helicobacter pylori is quite old..I remembered reading it in the sciece magazines in the 90s...!

That doctor deserved the nobel prize.

I was wondering what happened to stomach ulcers that were common a few decades ago, and now I got the answer. Thanks antibiotics.

I got gastritis but it was because I skipped lunches or breakfasts allot in college to save money..