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Discover the role of serotonin and why it's essential by exploring what does serotonin do, why serotonin is important, and the 2 serotonin receptor types.
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➡️Blogs mentioned: www.astralcodexten.com/, george3d6.com/
➡️Paper: www.ncbi.nlm.nih.gov/pmc/arti...
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The video delves into the complexities of serotonin, explaining its role beyond just being a happiness chemical. It discusses what serotonin does, emphasizing its influence on cognition, emotion, and motor control, and why serotonin is important, particularly in adaptive responses to adverse conditions. The transcript outlines two pathways influenced by serotonin receptor types: 5HT1A and 5HT2A. The former is associated with passive coping, improving stress tolerability, while the latter promotes active coping, facilitating changes in behavior or outlook to overcome stressors. The discussion extends to how different drugs interact with these pathways. SSRIs primarily stimulate 5HT1A, aiding passive coping, while psychedelics like psilocybin act on 5HT2A, promoting active coping. The video touches on the therapeutic potential of both SSRIs and psychedelics in treating depression, albeit with different mechanisms. It also highlights potential drawbacks, such as emotional blunting with SSRI use and the risk of developing unconventional beliefs with excessive 5HT2A stimulation.
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00:00 Overview of Serotonin
03:04 Serotonin's Two Pathways
05:08 Passive Coping and Active Coping
07:06 5HT1A and 5HT2A Receptors
06:29 5HT1A and 5HT2A Receptors
09:02 Tying It All Together
13:03 Balance and Considerations
15:01 Kickstarter!
#pmhnp #serotoninboost #serotonin