Hey! This episode was really fun to put together. Let me know what you think! Link to the podcast with Joe is in the video description

Nanomachines son. They harden to response of physical trauma. You can't hurt me COVID.

The only time where a doctor gets to say "Nanomachines son!" to your face

Hi, I'm a second year PhD student in nanomedicine. The tech shown in this video is clever and exciting, but functionally not dissimilar to formulations I've used preclinically before, and will face all the same issues current actively targeted nanoparticles do. Most importantly, there is not much difference at all between cancer cells and our cells, only slight differences such as overexpression of certain receptors and different metabolism rates. The purpose of a technology like the one shown is to increase the therapeutic window of an anti-tumoural agent, but it will still have a limited window. This vector will have off target effects - there is simply no way they are only targeting cancer cells. There is no treatment which only targets cancer cells. These innovations take decades to reach clinic. As we improve our biological understanding of tumours, we will see the viability of this technology improve. Personally, I think this technology has a great use case in anti-bacterial treatment, as viral vectors can exclusively target bacteria. I'll do some reading about this - super interesting and ty for the video.

Disease: WHY WON’T YOU DIE Me: Nano machines son

"Nanomachines, son" -Senator Armstrong

I would like to advocate for extreme caution for creating such things. Viruses mutate. If you use the same DNA to make your Nano robot then it is also subject to mutation. Hopefully well thought out and effective safe guards are put in place. Every thing that uses DNA or mRNA to replicate is potentially dangerous due to possible mutations just ask any biologist. I can see the promise of things like that but some of the worst things in history were done with the best intentions.

Senator Armstrong: You cant stop progress jack!😈

Nanomachines son!

Nanomachines, son! they harden in response to physical trauma

I wanna witness that era so bad

Nanomashines Son! They harden in response of physical trauma

Nano machines son, they harden in response to physical damage

call me crazy but I imagine a world where nanotechnology combined with crispr would be a game changer

I'm not opposed to this technology, it sounds promising, but the question scientists never seem to take seriously, "What could go wrong?"

"Why won't you die?!" "Nanomachines, son!"

I think the really cool stuff comes once we already have technology like that.. imagine the potential of nanodrones (not bots since you want them to be able to be controlled from the outside) inside the brain... just casually hooking into different neurons, getting instant feedback from the owner of said brain.. or building complex structures inside the body without ever needing surgery.. its gonna be crazy :)

I always figured something like this would be the future of medicine. Harnessing the power of lifeforms that are built to penetrate the body just makes sense.

NANOMACHINES SON THEY HARDEN IN RESPONSE TO PHYSICAL TRAUMA

"Nanomachines son, they harden in response to physical truama"

Woooow! That was a very interesting video. Full of information that kind brought me hope for a future where we don’t struggle with cancer anymore. But a question comes to my head, if we are able to create this virus to insert something inside of the cell, how easily it would be to create bio weapons with this same technology … Or maybe I’m watching too many movies hahaha 😂

The universe looks like a giant cell. Especially on the Interior!!

Our favorite Senator must be very proud right now

will there be nano machines that can harden in response to physical trauma?

Thanks to some smart algorithm, I became aware of your channel. Just Outstanding! Keep up the good work! Subscribed.

You know, I might be delighted if I wasn't terrified after being shown for the last 3+ years just what the pharmaceutical industry is capable of. Personally, I doubt that little trust I had before is ever coming back, but hey, that's just me, I don't mean to spoil your optimism. Also, at least for now, it seems to me that it's not so much of a "one size fits all" as it's "no size fits at all". But I suppose that's going to improve with time and more work. Too bad, as I've otherwise been a real technology geek, including the pharmaceutical innovations, but this field at least had become a red zone for me.

One of the major companies that starts using these methods should name themselves Umbrella Corp!

I watched this video, and I see this ending really bad.

I really appreciate your motivation to teach us.

Virus: "Why won't you die!!" Virus Victim: "NANOMACHINES, SON!"

And then the nanos mutate and turn everyone into flesh eating zombies :)

You have a way of presenting or explaining ideas in an easy to understand approach even the ordinary man on the street can comprehend. For this reason, I am thanking you.

Congrats, you just perfectly explained mRNA jabs, as those make use of lipid nanoparticles to deliver the mRNA to the targeted cell

This best lecture. Your potential to deliver around 5 chapters make you a characteristic of a good practitioner. The technology Nanosyrinx and nanorobotics are amazingly growing faster In the era of Nanomedicine. It is interesting and practically implemented nanotechnology like Genome editing, and CRISPR Cas 9. With thanks.

Oh how Joe would love to be in charge of our medical needs!

How to prevent mutations to these "robot viruses" , that can potentially wipe out humanity?

At the mean time, custom designed deadly virus can be made too.

I can see it now "Nano-Bot Syndrome" predicted on January 1, 2023

I feel like i'm watching one of the intro trailers for a new Resident Evil game. 100% would play by the way.

All this stuff excites me personally, but I cant help but share the sentiment of caution

The fact that people can now make custom made viruses just scares me.

Meanwhile Meta is spending hundreds of billions on VR and delivering PS1 graphics

If this works people we are going to witness miracles ! . Just have to live long enough to get to the point the technology is widely available to the public.

great, lets scale this up BIG.

As long as it's trying to help people, I mean not be umbrella at the same time, I'll 100% agree.

Ok... But do we have that technology or everything is a concept of things that are going to come in a near or far future? At least do we have this approved and financed to develop all this in a big number to do a massive exportation to the world? Don't miss understand me all is good to hear, but we need constantly actualizations of this kind of information and also we need to know in what point we are at the moment.

Gosh - I wish you could produce some videos for my favorite you tubers...so professional.

Thank you so much for making and sharing this nice video.

Seeing the circular genetic design, and the cool looking virus thingy at first looked weird... but then by 10:07 going back to it after explaining everything - this virus/payload system seems like it will be the future of medicine, and preferably in my lifetime would be great!! lol. I imagine it will be somewhat expensive for a while until they are able to mass-produce these 'fixing' pills or liquids for anyone to take. I also feel like we've all had that thought too, and this idea brings it to life - "medicine... without the side effects"

Wow! 🤯 What a time to be alive!!! Incredible! Thank you!!! 💖🙏💐

Haha... The bot section is very, VERY strong on this video... Let's inject tiny robots inside our bodies. What could possibly go wrong..?

Leveraging viruses as vehicles is where Gain of Function research comes in, correct? Which opens the possibility for pandemics such as covid...sometimes things are pretty cool, but sometimes those things should be steered clear of.

They harden in response to physical trauma.

We need it sooner than later

It appears that more nanotechnology/ nanobots videos are beginning to resurface. This was not the case before, as these types of videos were created a decade ago. I believe current advancements of technologies have met the requirements of developing nanotechnology/nanorobots, and have therefore set the stage for a new age to come in the healthcare industry.

SPOILER ALERT: Nanotech is already inside you, they did not ask you before they put in there, you asked for it.... well done.....

I've always thought that the next major leap forward society will take will be a biological one.

What about mutation? Couldn't they evolve to spread to cells that aren't meant to be targetted?

Literally, the plot to "I Am Legend" lol

If you think of it we are naturally occurring nanotech robots!

"Hey Ferb I know what we are gonna do today!"

Thanks for clarifying the concept with that knight that says "ni". I would not have gotten it by any other means.

When time comes, we do not have to seek a doctor when something is wrong, the nanobots will be able to send a read signal from the body to a doctor, that a symptom has occured and the patient won't even have to think about what is prescribed or have the feeling of a symptom will show. It is like walking around with a hidden cold.

Okay the Pokemon reference alone earned you a subscription...

Do you want Aliens? Because this is how you get Aliens....

Can you provide a link to the soundtrack starting at 1:13?

Nano machines son!

Imagine a creature rampant with disease, flesh rotting, and a mind rampant with the psychosis of an extended life and what that can do to the human mind. Immortal and living in the gap between life and death a true horror against the laws of nature. The nanobots inside care nothing for the host, but only worry about the efficiency by which they keep their symbiotic host “alive”. Nothing can be closer to the word “zombie”, what a huge mistake.

Knock knock… Who’s there? Gain of func… We are the Borg…

demon outro

Still waiting for the MED-BED!👍👍😇

Excuse that I have forgotten your brother Paul Denton and the infinite power of nano-augmentation. -Deus Ex

Thank you! Just subscribed! Keep it up

Remember as of now, they can't control were they go. That makes them very dangerous.

Embalmers puzzled by frighteningly odd blood clots..... Nano Robots: "Hold my MRNA IPA"

Great video, informative. Thanks

Love the edit

So you want to engineer an artificial killer T cell? What could go wrong?

This video is fantastic, and I am thankful for it. However, cancer is a nasty illness, and I believe that everyone, regardless of their issues, should seek care. I strongly advise cancer patients to join support groups so they do not have to go through it alone. Sometimes having someone who has been through what you are going through is preferable than having someone who can only fathom what you are going through. Personally, I suggest the Truth About Cancer support group. This group has about 6000 members who all support each other. They investigate alternative cancer therapies, which are really beneficial. This group can be found on the social media site facebook. I really hope that everyone survives and overcomes this dreadful illness!

Nanomachines Son!

This is why I’m a Chem-Bio major

Are those bacteriophages you are referencing? Those bacteria in the animation look a lot like bacteriophages.

There surely will be incredible stuff in the future, but mostly only the rich will be able to afford it.

Real interesting stuff. Shame Big Pharma will price these treatments way beyond the grasp of the average family.

We needed Osmosis Jones in here, stat!

Every 10 yrs you hear about these being built, each time advertised differently (just whatever the public will buy). But they never get, or are secretly.

"You wont see these self replicating..." Jeff Goldblum ... cough cough...

odd that there are so few toutube videos about self replicating nanobots, especially since that's the most revolutionizing technology that could become available near term

I'd like to be excited about these developments, but even the the most paranoid tin foil hat wearing conspiracy theorist would have a solid point about tiny machines going through our bloodstream being a bad thing in our society. Let's ground ourselves to reality here, yes nano robots could do many great things to actually help people, but people can and will be awful. If an awful person has a significant amount of money and influence coupled with an ulterior motive then has say so over technology like nano robots, then it is definitely going to be altered to be used in a malicious way. So yeah. I'm more worried about developments like this because we don't live in a perfect world where we make things solely to help one another without inflicting harm.

Right now scientists created cures for most viruses but the virus vector is where the problem consists, they just can't figure out how to get the cures to those cells which shows how complicated that specific area is to this field

This is pretty amazing.

Wow so you are a real Doctor KZfaqr? wow, I am bipolar and have mental illness, and comment on youtube as my mental illness.

nano machines?!

Found my next stock investment lol thanks for the video. Nano tech will be huge.

Good way to kill ennemies while staying unnoticed. First use of science is always military and evil. So People die and nobody can accuse you.

We are one day closer to Project FOXDIE / Heracules.

Eat your heart out, J.C. Denton. 💪😎✌️

The outro 💀

Nowadays everything changes everything forever, meanwhile people are living a pretty miserable life.

Maybe we will be more motivated to take care of our environment if we know we will have to live through it for hundreds of years