Hi DSBaker! Congratulations on 44 years and counting! It's not an easy game, this T1D. You sound like your resilience has supported you along the way. I have a 100-page guide to exercising with T1D that teaches new things even to those with decades under the belt! You might find it helpful. Nonetheless, don't give up! I hope we see a cure of some kind in our lifetimes! Thank you for watching!

​@@DiabetesNerdmam i am from India my brother in t2d please told me when come this medicine please mam replay or make a video

@@amanmodanwal795 yes, it will be many years but I will let you know how this research develops.

I guess we've gotta wait and see! Thank you for watching -- and congrats on 66 years and counting with T1D!

Too much $ @ risk unfortunately for there to be a cure ,hopefully Vertex pharmaceuticals can change lots of people's lives absolutely, positively. 🙏

@@DiabetesNerd Not a single chance ... soon as the one treatment will be available all those company , are think only for their +$ , will stop that treatment to be used for diabetes type 1...unfortunately for ones are have hope !

Look forward to a dependable permanent procedure to Cre type 1 DM

Thanks for watching, Jim!!!

Well said, Bennet! Thank you for watching!

I love this! Thank you for this video. I now have some optimism for a cure back one day.

We gotta have hope!@@bethbaskett3

Yup. Research has come a long way in the last 20 years. There are so many companies developing insulin-producing stem cells or therapies and ways to hide those cells from the immune system. It's still well down the road but I do believe future generations won't be taking insulin injections every day.

Thank you for watching, Carlos!

Faustman's research is interesting but there conclusions of what's worked with the BCG vaccine are a little fuzzy. I'll work on it. ;) Thank you for the topic! I've written about it here: www.healthline.com/healthy/dr-faustmans-controversial-diabetes-cure-research-continues

2. 🏭 Manufacturing Commitment 🔹 On August 30th, 2023 Vertex and Lonza broke ground on a large manufacturing facility in New Hampshire, expected to be operational by 2025. This step demonstrates Vertex's readiness to deliver therapies promptly if trials are successful. 3. 💬 Perspectives on Immunosuppression 🔹 Immunosuppression, an unavoidable component of VX-880, often raises concerns due to its risks, as you point out, but… 🔹 Aaron J. Kowalski, Ph.D. is the JDRF CEO, a scientist, and someone living with T1D. I feel his perspective is uniquely well-informed given his position. 🔹Last September he was on a TCOYD panel and recounted this: "The big next question is, would you do it (VX-880)? So the folks at Vertex flat out asked me when I was in Boston. They said, 'Would you do this?' I said, 'I don't know. I got to think about that.' And I went home and I said to my wife, 'I was just blown away by what they were doing. I mean, absolutely blown away.' And I said to my wife, 'I think I would do it.' She goes, 'No, no, you don't want immunosuppressants.' And I'm like, 'I kind of don't want diabetes’” 🔹 Hearing that opened my mind to a different perspective and reminded me to not forget that while immunosuppression carries risks, so does T1D! 🔹 Dr. Kowalski also added “One of the big things for us at JRF now is actually advocating for broader access to these clinical trials. And ultimately, I firmly believe that any adult with type 1 diabetes in the United States, they and their doctors should have the decision to make that decision. Do I want to take immunosuppressants or not? Not the FDA, because right now they're limiting it."

🧬 Viacyte's VCTX-211 Trial 🔹 In collaboration with CRISPR Therapeutics, this trial focuses on genetically modified cells to avoid immune attacks, with completion anticipated in 2025. 🔹 Vertex's acquisition of Viacyte in 2022 and a March 2023 agreement with CRISPR Therapeutics are a heartening indication of Vertex’s commitment to this cause. The knowledge sharing that their investments in these companies is likely creating is unlike anything I’ve seen in the past. 🌟 Your video inspired these reflections, Ginger. I hope this additional information fuels further optimism for a future free from type 1 diabetes. Keep up the good work!

Thank you, Brady! From what I know, VX-264 is still recruiting right now. Sounds like they are definitely looking for more than just 6 participants so that's great! Thanks for the info -- and for watching!

@@BradyT1D And yes! That news about the manufacturing facility was super exciting last year!!! Aaron Kowalski has been an incredible advocate in supporting and furthering this research through the JDRF! I've had the pleasure of meeting him in real life and there is no doubt he is 100% dedicated to changing what it means to live with T1D.

@@DiabetesNerd That's great to hear. He seems like the right leader at the right time for JDRF. I also meant to post this, but I don't think it made it in my original long comment: 🧬 Viacyte's VCTX-211 Trial 🔹 In collaboration with CRISPR Therapeutics, this trial focuses on genetically modified cells to avoid immune attacks, with completion anticipated in 2025. 🔹 Vertex's acquisition of Viacyte in 2022 and a March 2023 agreement with CRISPR Therapeutics are a heartening indication of Vertex’s commitment to this cause. The knowledge sharing that their investments in these companies is likely creating is unlike anything I’ve seen in the past. 🌟 Your video inspired these reflections, Ginger. I hope this additional information fuels further optimism for a future free from type 1 diabetes. Keep up the good work!

Thanks for watching, Mr. Franklin!

I have a whole video about SErnova right here: kzfaq.info/get/bejne/h5aknJp5ma3KpnU.html I'm working with Diamyd on a video right now! Stay tuned!

Yes! I think having a little hope is a good thing. Thank you for watching!

@@DiabetesNerd Pleasure 😊

I will look into this ASAP! THank you!

YES!

Hi there! I have a video all about Sernova's cure research right here: kzfaq.info/get/bejne/h5aknJp5ma3KpnU.html

Yes, you're not alone in this theory. Many people believe a cure will be blocked. But the people developing cures ALSO have a LOT of money. Vertex is a HUGE company. Bigger than Dexcom. Meanwhile, insulin companies have far more type 2s to sell insulin too, and they're making 100X more from GLP-1 medications like Ozempic, so their need to sell insulin to type 1s really isn't what keeps their lights on. The conspiracies about a cure being blocked just don't make sense when you learn more about these finer details of how those companies are really making their billions. I appreciate the skepticism nonetheless! Congrats on 40 years!

oh my God, poor you, my son says the same all the time, but I started to read Dr Bernstein's book, he is 89 doctor with type 1, he handles it pretty well, he gives a little hope. Best wishes to you❤

Your immune system knows the difference between your body's only insulin-producing cells and foreigner cells from outside your body. They can't make the transplanted cells represent your own DNA. Instead, they can give you those cells but then protect the cells from your immune system. That's what these functional cures focus one. Watch my other video about cure research here: kzfaq.info/get/bejne/h5aknJp5ma3KpnU.html

Way too soon to determine! They’ve got a lot more steps in their clinical trial to get thru. All we can do is wait and hope. ❤️

I do not have that information

Ok

Food does not cause or cure diabetes.

@@DiabetesNerd I think that inflammation is a root cause of T1D. According to Dr. Robert Lustig our western diet is full of inflammatory factors like omega-6 oils, fructose, and wheat proteins in the processed food. Even in the food for kids, that's terrible 😔 (I've only counted the sugars in the diary). I'm lucky to live in Europe. I reversed early stage of T2D by quiting any processed food, adding good fats and the fiber. Yes, it cost a lot of time cooking for myself from whole foods. But I can control what I eat. I hope that people with T1D will find a successfully treatment for this terrible disease.

Absolutely!!!!

That's why I am here. I am letting the management of my disease destroy my life.

Hi Mike! Yes, that news came out a couple weeks after I published this. It's heartbreaking. Fortunately, their deaths were unrelated to the trial. The families have chosen not to release the personal details on their deaths. Definitely thinking of those families -- and grateful to these two participants for their dedication to cure research!

Diabetes daily just did an article about this both weren't related to the study.

YES! Those would be two VERY different treatments since the deeper mechanics of the two diseases are very different.

No cure, just a better pump?

Hi there, I said "other diseases"...not "other autoimmune diseases"...

Ok I am sorry You said "other diseases" . I want to know the names of these diseases.

@@atulgupta7262 Polio, tetanus, HPV, small pox, chicken pox, whooping cough, measles, hepatitus....all of these have been eradicated through the development of vaccines. This video you're commenting on describes this research as a "functional cure"....but other T1D research is working on preventing the disease from its full onset altogether.

Thank you for information

When six-month-old babies develop type 1 diabetes, it disproves these "what you eat" theories. Studies have looked at gut bacteria in people with type 1, and there is a difference in the bacteria compared to non-diabetics, but they theorize that it's a post-diagnosis change. Type 1 diabetes is complicated.