9 years later and you helped me understand this ! Thank you

8 years passed and your video helps me understand. Thank you 😭😭

An cohesive narrative that makes sense?! Congrats you write notes and explain things better than my lecturer did about this. It confused the hell out of me until I found this. :P

Dont wanna sound racist but after listening videos with indian accent, this video made my day

THIS WAS GREAT keep up the good work mate

Thanks, you made this so much more clear to me!

This is a great explanation! Much better than trying to decipher it from a figure in a textbook!!

Absolutely loved this video. Thank you very much from Colombia. 💕

Amazing explanation! I couldn't understand how it worked from primary sources, but you made it clear.

Damn this was really good, thank you so much for making it so concise and clear :D

too bad i can't cite this. i'm working on a paper about genome editing and medical journals are basically unreadable. thank you so much for making this information more digestible. (Edit: I found some journals that I could pick out some information from. Obviously not all of it made sense, but it was enough for me to know what I was doing. This video still helped me on what to look for in my sources. The paper got a good grade.)

Great! loved this!

super explaination.It acted as a source for clearing my doubts

Really nice video and a very helpful review before my gene therapy exam. Good work!

i wish i can thank you in person , you helped much with my presentation tomorrow

What a great explanation!!!

You're the best, thx!!!

This is great. Thanks

amasing talent of teaching

You are amazing, thank you!!!!!

This is awesome ,Thank you

really good, thank you so much for making it

Thank you so much for this video :)

Awesome. Thanks!

CRISPR/Cas disliked this video

Cheers dude!

Thanks!!!

hi thank u for this!!!

fantastic !

hi, in image you've drawn is upper part of folk different from bottom part? if not can same sequence as above rotate 180 degree and cut some symmetric genome?

awsome presentation 👍

if i were to use the information from this video in a report, what scientific journal/publication could i quote for references?

Could you make a "blunt end" DNA break by positioning the endonucleases closer together (making a smaller spacer region) ?

that's great!

Amazing tutorial!! Have my final paper on recombinant DNA tech you're my saviour!! One point, its Fok1 and not FokL. Great video otherwise bruv!

One thing I am interested in is the exact mechanism by which the desired genes are delivered to a target site? For example, lets say you want to change skin colour or density in a specific part of the body, how does one actually go about applying it? If ZFN is not utilizing a viral catalyst, then what is the (presumably liquid) solution being administered, and is this solution proprietary? Do I have to pay a lab somewhere to create a soup loaded with the gene modifiers I want? Can it be applied directly to the skin to take affect?

thank you

Explained well but doesn't zinc finger produces blunt ends and four of them work together instead of two? Am I missing something?

It's FokI (FOK1) not FokL

Very helpful 👍

ربنا يباركلك يا بن يا ابن جرسايد

nice lecture

This video helped me a lot, you explained it very well! Thank you! There is however a very annoying beep noice in the background, it is kind of distracting. Maybe you could work on that next time?

Thank you so much

Videos this well and clearly explained make me question why i pay for university classes

Is there any videos about CRSIPER/CAS9.. if there isn't please make one i like your explanation so much

Question: does this explain why the therapy (Zinc ionophore +Zinc) could help against COVID19? 🤔 I read our ribosomes can go into hibernation if Zinc finger is missing which make them susceptible to be hijacked by viruses to replicate themselves. And how does copper and zinc work together?🤔 Thanks in advance for any answers!👍

Really annoying high frequency noise in this video. Please figure it out.

Is it FOKL? or FOK1?

Is this what our next vaccine is going to be ?

sorry, but it is the Fok1 nuclease not FokL

Thanks :) by the way *Fok1 .... (Fok One)

It's FOK 1!!!! NOT "L" . That's a huge mistake which should be corrected.

basically, you say "basically" waaaaay too much, basically

My gaydar is going off

Every year I have to relearn this bullcrap for my exams. Every year I come across this video and every year I become a little gayer.