7 ай бұрын
Пікірлер
@HTAKJGW 11 сағат бұрын
We’re all different? Hang on I thought we were all equal according to the radical left loonies running the US at the moment.
@HTAKJGW 12 сағат бұрын
Parkinson’s “experts” are failing. And yet they’re apprehensive to accept alternate ideas and conduct large clinical trials. Maybe that’s why they’re failing! Disgraceful. My father has Parkinson’s and the specialists are defeatest. Just collect their cheque and do nothing but supportive care as the patients deteriorate. They are failing and the neurology industry in this space that also covers Dementia and alzheimers needs a major overhaul.
@judyboehm5215 19 сағат бұрын
keto diet. carnivore diet improves symptoms. micro biome
@judyboehm5215 19 сағат бұрын
I use Platinum Red Light Therapy. i jave commercial frequency highest. it has helped me with being hit a lot as a child with brute force. it is helping me a lot. i just got the Mito helmet and nose clip device like violets to go thru sinus under temporal lobe. very helpful. i’m add and it’s helping me now at 76
@Bill_Ross 20 сағат бұрын
Has anyone looked into upregulation of VMAT-2 to push more of the cytoplasmic dopamine into vesicles? Tricyclic and Tetracyclic antidepressants do that. Is that what he is talking about? www.ncbi.nlm.nih.gov/pmc/articles/PMC10592782/#:~:text=PMC%20and%20PubMed.-,Tricyclic%20and%20tetracyclic%20antidepressants%20upregulate%20VMAT2,rescue%20disease%2Dcausing%20VMAT2%20variants
@annb5610 Күн бұрын
Does All this work for an MSA-P diagnosis??
@Positivevibes8300 Күн бұрын
Question: my husband was diagnosed with PD in 2021 during his chemotherapy sessions. He had some rare tremors before his whippel surgery and before the chemotherapy sessions but the shaking and the PD symptoms get triggered after the chemotherapy. Is there any relation between chemotherapy and PD? Thank you 🙏
@user-tl5ix8bs5n Күн бұрын
Where can I buy the helmet at from New York City j?D 17:10
@kennethdarlington682 3 күн бұрын
‘‘I am not only happy am alive but also glad that "#DrMadida" was able treat and cure me with his herbal medication of my parosmia, Meniere disease and Parkinson disease (PD) 🦠🦠with their herbal treatment. My smile is so bright because I am happy 😊😊😊’’.
@carolbrenner3121 4 күн бұрын
❤I have regular daily bowel moments ❤
@carolbrenner3121 4 күн бұрын
Lost over 100 lbs intermittent fasting ❤
@carolbrenner3121 4 күн бұрын
❤helped ❤ Pendulum Life, liver cleanse
@user-tl5ix8bs5n 4 күн бұрын
Do you think you're using the red light and grow here?Someone suffering with , p as 3:03
@user-tl5ix8bs5n 4 күн бұрын
Do
@thorcarnivore 7 күн бұрын
I have seen several people with Parkinsons and MS getting cured when they started eating the Carnivore Diet. It's a ketogenic diet and it's curing millions of people from a lot of things. Look up "I ate ONLY ONE food and my Parkinsons reversed" Mimi Morgan.... "Angry with Neurologist!! Multiple Sclerosis & the Carnivore Diet.".... "Hope for Alzheimer's & Parkinson's with Metabolic Neurology - Matthew Phillips MD Ken Berry MD..
@coryarts 7 күн бұрын
just got the duo coronet as I type this, let's see if I notice any changes. My boss doesn't believe in photobio modulation, prove him wrong
@DavidHowes-h4x 8 күн бұрын
Michael Okun in his 'nosilverbullet' video says that there is no long term benefit in delaying levodopa, quoting the early vs. delayed levodopa study from Italy and the African cohort study. This research found that early initiation of levodopa did not lead to worse outcomes in the long term compared to delayed initiation, impying that levodopa does not accelerate disease progression. This seems to contradict Jonathan's theory doesn't it?
@ground752 9 күн бұрын
Paraquat poisoning
@RobertBrown-yb3ur 12 күн бұрын
Interesting that the links to the papers don't work. Someone cave to big pharma pressure?
@wadehuffaker9327 12 күн бұрын
I don't use the Parkinson's drugs. I've had Parkinson's for 14 years. I got to stage 3 and reversed back to almost no symptoms at all. I think he's on the right path,, but hasn't connected all the dots yet. My question is,, if you get rid of the dopamine,, what do you replace it with? And since a lot of the dysfunction of Parkinson's happens also in the mitochondria,, what does lowering dopamine do to help the mitochondria? My guess is,, not much. I would really like to talk with Dr. Jonathan Sackner Bernstien,, maybe compare some notes,, let him know what I have found.
@rrichard2422 12 күн бұрын
Vegan, wheat free diet..No Coffee or Alcohol. Restricted eating. Gut health. Exercise, Cardio, Resistance,Yoga.& Breath work. Also Imaginary Exercise. Meditation & Sleep management. Red light & avoiding LEDs. Vibration gloves. Self esteem. Not identifying with a negative thing. Big P.lans with visualisation of details. Diverse Real social life. Brain exercises. Learning new things. Usual supplements including Lithium. Hot & Cold therapy. Avoiding toxins obviously... ?
@mwswis 10 күн бұрын
What did you do to reverse the symptoms?
@wadehuffaker9327 10 күн бұрын
@@mwswis About four years ago I was starting to rapidly decline,, things were getting worse,, more symptoms started to appear. One of those symptoms was my appetite,, I was hungry all the time. So I researched for appetite suppressants,, found the oldest suppressant,, Nicotine. Did research on pure nicotine,, amazed at all the health benefits and found that it had been studied for use on Parkinson's. Started using nicotine patches,, the results were amazing! Not only did my appetite improve,, a lot of my other symptoms either improved or completely went away. The nicotine patches were expensive and would irritate my skin,, so I switched to using the nicotine pouches you put between your cheek and gum (Product names: Zyn, Velo, On, Lucy, Rogue, ect.) and still occasionally use the patches for muscle tightness. About six months later I started getting a resting tremor in my left hand. Did more research. Started taking low dose Methylene Blue. Haven't had a tremor since. I also (carefully) use Glutathione,, high dose vitamin B1 and other various supplements and I'm also on the carnivore diet.
@wadehuffaker9327 8 күн бұрын
@@mwswis Tried to respond,, KZfaq removed my reply,, don't know why.
@thetraceys7891 5 күн бұрын
@@wadehuffaker9327Try to respond again.
@whig01 14 күн бұрын
I looked up metyrosine to see its side effects and that's a hard no for me. Literally causes the symptoms you don't want.
@chinko1953 12 күн бұрын
Metyrosine was first approved for use in the United States in 1979. It is also sold under the brand name Demser, which comes in 250 mg capsules for oral administration. However, metyrosine can have adverse effects, including making Parkinson's disease worse. It can also increase the effects of liver disease because the body removes it more slowly. For this reason, it is important to take metyrosine only as directed by a doctor.              
@pilotwolfram6192 17 күн бұрын
Interested to know if over production of dopamine is evident in early PD patients not taking levodopa.
@DCGreenZone 17 күн бұрын
Look into Palmitoylethanolamide.
@marilynbuckner1353 19 күн бұрын
President Biden signed a bill today July 3 for millions for PD research I hope you get some research dollars
@jonathansackner-bernstein 11 күн бұрын
This is important law, but it provides for oversight of research rather than funding for research.
@oaazh1 21 күн бұрын
Please remember, almost all leading Parkinson’s treatment centres/ hospitals, get large grants and research budgets each year to continue research work and expand their presence across more cities and countries etc, to treat growing numbers of patients… Many or some of these grants and sponsorship of events and other financial help comes from big pharma, that is manufacturing drugs they prescribe. So all the hospitals that pride themselves as centres of excellence for Parkinson’s treatment, are running along a set path, where dopamine or dopamine agonists are the only go-to medications for now, so they will naturally not support any new contrary medication or research, unless it is by a big pharma name.
@user-pc5ek7fn5u 23 күн бұрын
interesting, when i was in hospital with pneumonia they decreased my dopamine intake and for 5 weeks i felt much better and had next to no shaking, then when i came out they increased my sinimet and i feel really ill with it
@hangingwiththegrlz4891 23 күн бұрын
The monkey on the left looks more docile and the monkey on the right looks pissed off and strong. I wonder how long the monkey on the right was restricted from food? Was it weeks in his lifespan or a few days a month?
@AFAblacksheepAFA 24 күн бұрын
55:27 1 mg of Protein per Kg of bodyweight? That is not even possible. Thats literally no protein at all. She must mean 1 g of Protein
@viyye 24 күн бұрын
I am 95% sure I have found the drug he us talking about, it is called Metyrosine
@marilynbuckner1353 19 күн бұрын
My husband has had good results with stem cell iv so look for stem cell doctor and bank your cells
@rkymtngal 17 күн бұрын
Why do you feel that and what are your thoughts
@viyye 17 күн бұрын
@@rkymtngal the guy is trying to get funding for trials so that he can make a heap of money for himself and his investors, that's why he doesn't want to give the name of the medication. I analysed everything he said about the medication and this is the best and only fit.
@viyye 17 күн бұрын
@@rkymtngal looks like these pharmabros are deleting my replies, As I said before this guy is withholding the name of the medication so that he and his future investors can go around and secure certain rights to it and make billions The drug is already fda approved and is on the market, but rather than revealing it and allow people to make use of it, he withholds it for greeds sake
@Bigboss-tl2wk 11 күн бұрын
@@marilynbuckner1353 can you give more informations please ? My husband has pd too.
@redlightglassesonthischannel 27 күн бұрын
Fascinating work, thank you , nice presentation
@studioandreruocco 27 күн бұрын
I was diagnosed PD on February 2024 by DATSCAN®. My question is: if Dopamine levels are too high in the brain of PD patients, why my DATSCAN® shows low levels of Dopamine in my Caudate and Putamen? Thank you!
@jonathansackner-bernstein 24 күн бұрын
DATSCANs cannot see what is happening at the level of individual cells. So while it is true that the total amount of dopamine in your brain tissue is low, the amount inside the individual cells of interest is very high. Think of it this way; if you looked at wealth for a prosperous city, it would be very high. But that doesn't mean that there are not a lot of people in such a city who are struggling financially. Understanding the resolution possible with a measurement is important.
@suzannelaw4811 5 күн бұрын
@@jonathansackner-bernstein😊
@suzannelaw4811 5 күн бұрын
9
@Mimi_745 2 күн бұрын
It sounds kind of like the way the body reacts with insulin resistance that it is reacting to try to increase dopamine when there is plenty of dopamine, it is just in the wrong place.
@jackcarls2893 28 күн бұрын
I agree. As I have personally made the decision to reduced my c/l dopamine regimen to the basic minimum 25/100 c/l, 3-4 x/day, I have experienced less symptoms.
@Gundog55 28 күн бұрын
I have gotten better after doing several things of which I’m not sure which has done it. Diet, exercise, specific yoga for the disease, supplements, red light therapy or exosomes. My neurologist told me that I was better than when she first saw me and that most people couldn’t of done what I have done. My response was “They could but most just don’t want to.”
@rkymtngal 17 күн бұрын
Can you be more detailed about what have you done for your diet, what specific exercises and specific yoga
@Gundog55 17 күн бұрын
@@rkymtngal Sure, I do intermittent fasting. I don’t eat after 6:00pm. When I wake I have bullet proof coffee, smallest setting in the Kurig, ghee, coconut milk, 5 grams of creatine, MCT oil, and collagen peptide. I don’t eat until after 2:00pm mostly fruits meats and avoid carbs. I eat a full dinner by 6:00pm. I take supplements, B complex, C, D3 with K2, magnesium, citrate, NAC, Zinc with copper, L-Tyrosine, L-Theanine, High grade fish oil, TRU Niagin. I only take cold showers. I have a sauna and do that three to four times a week. I try to achieve at least 12,000 steps a day. I lost 29 pounds through all of this. I took 100mg of B1 sublingually for 3 months which releaved my neuropathy in my right foot. As for yoga, it is a certain routine that my yoga instructor developed for me. She was trained by the yoga instructor at San Francisco Hospital’s Parkinson’s Center. I take a CBD gummy before bed which helps with my sleep and have recently been taking quinine at night which has ended my leg cramps. I have learned to avoid stress by dropping expectations. I focus on relaxing and working on my spiritual outlook. Hope this helps.
@VeryLikeLeigh 7 күн бұрын
Exactly what type of diet?
@Gundog55 5 күн бұрын
@@VeryLikeLeigh I have in the morning butter coffee with coconut milk, ghee, creatine, MCT oil. Then I don’t eat until after 2:00pm. I try to stay away from dairy, sugar and carbs. I don’t eat after 7:00pm
@tinakehoe2168 28 күн бұрын
So they are repurposing a drug to replace the drug Sinemet??
@user-pc5ek7fn5u 23 күн бұрын
sinemet makes me really ill
@anhumblemessengerofthelawo3858 28 күн бұрын
PD is (potentially) caused by the millions of tons of aluminum barium strontium manganese surfactants plastics etc that are placed in the sky to block the Sun, everyday. Literally poisoned air. Neurotoxins.
@annb5610 29 күн бұрын
I have been trying to get a team Far over 2 years now useless UCSD..... Mayo clinic all horrible.
@jrmds2108 29 күн бұрын
Thank you... excellent and clear Where do I sign up? Can I sign up???
@beweslee 29 күн бұрын
Michel, the information you and Mark have shared has been something that has helped me, from the inside out. I am an Emergency Medicine physician, and without a diagnosis of Parkinson's, as well as my patients. My Mom had Lewy Body Disease, and it became clear to me that there were signs very very early on.
@nosilverbullet4pd998 28 күн бұрын
Thank you very much !
@connyhaden3035 28 күн бұрын
iiiieiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiieiiiiiiiiiiiiiiiiiiiiiiieèeeeèeeeiiiiiiìiìiiiiiiiiiiiiiiuuueiuuuueeeeeuiuuiueewueuwewiiuiiiiiiiiiuiiueweieuiiiwiuiiiiiiiiiiiiiiiiiiiiriuwk4ilwklilllkrlielwiwriirirrfriewifiwiirifiwiieiwiuiuiriwwwwiuieerruwiwiieriiririreiiiiiieuiiwiriiriieiiieiiiiieiiuiiiiiiiriieiiiieiiwiirriiriwiiiwwwieewweiwfwewiuiriwiiriiiiiriiiiiiuieiwieiueiiiiieeiiuiiiiiiieiiiiiieuiiwiriiriieiiieiiiiieiiuiiiiiiiriieiiiieiiwiirriiriwiiiwwwieewweiwfwewiuiriwiiriiiiiriiiiiiuieiwieiueiiiiieeii iiiiiiiiiiiiiiiiiiiieiiiiuiiuiiiuiiiiuiiiuiiuiiiiiiiuiiiiiiiiiiiuiiiiuiiuiiiiuuiuuuiiiiiiiiuiiiiiiiiiiuiiiiiiiuiuuiiuiiiuiiiiiiiiiiiiiiiiiiiiiiiiiieiiiiuiiuiiiuiiiiuiiiuiiuiiiiiiiuiiiiiiiiiiiuiiiiuiiuiiiiuuiuuuiiiiiiiiuiiiiiiiiiiuiiiiiiiuiuuiiui iiiuiuuuiiuuiiiiiiiiuiiiiuiuiiiiiiiuiiiiuuiiiiiiiiiiiiuiiiiuiiiiiiiiiiiiiuiuiiiiuuiiiuuiiuiiuiiiuuiuiiuuuuuiiiiiuiiiiiiiiiiiiiuiiiiiiiiiiuiuuiiiiiiiuiiiiiiuiuiiiuiuiuiiiuiuiiiiiiuiiuuiuiiuuiiiuiiiiuiiuiiuiuiiuiuuuuuuuuuuuuuuuuiuuiiiuiiuuuuuuuiuuuuiuuuuuushui to iuuuiiuiuiuuuuuuuuuuuuuuuuuii7uuuuuuu7shinjuku7u7777u77777777u77uuuuuuuuu7u7uuuuuuuuuu777u77u777u7iuuuuuuuu77deere 7k k 7777k k 7k kkk 7kk 7kk 7kk 7http http 77hrs I 7was 7you kid you you i i i 7777i i 77i have kick7k kick7k 777kick7k 7k 7777k 7k 7u77777wiki 777u7u77777777u77uu7777uu77u7😢😊 1:00:26 🎉🎉uuu777u7kick7kuu7u77777u77777757567ŕrr7r7ry7777777ŕrr77th 77yyuyryr7777guilty yuk thoughtful7guilty 7thoughtful7guilty thoughtful7guilty thoughtful7guilty 77thuggish7r7uyyyyury7r77ryyyyyy7y777yyyyyrruyy7rrr7yyryyyryy77yyyyyyyryyyyyurr7yy7yy7ryyyyryuuyry7yryyy7thuggery r7777yyy7yyyyyyyyyyrryyyry7y7yyy7ry7r7r77y7y7yyy7yy7y7hutu ry77ryyyryyyyyyuyyyyrryyry7yryyyy7yyyyy7yyy7ryy7yyuyyyryryyyyyyyy ryyryyyyyyyyyyryyyyryyyyyyy y7r7r7ryy7777kick7k t gutting gutting yay I thuggery thuggery was 7yyyy7yyyrry7r7777yyyryryy7ryyyyy777haughty 7to y7yryyŕŕ❤ql1😢😮😮😢
@nancymallon1898 29 күн бұрын
How do I ask a question and get an answer?
@normanrubenzer Ай бұрын
this is very intresting, if this is true ,there would be millons of pd sueing . that is why no one will go forward with this. plus there needs to be a way to detoxify the brain for this dopamine. my wife has advanced pd and is really strugging. i always had a gut feeling that to much carbidopa would have bad side effects. its very depressing to see your wife of 40 years dwindle away to nothing.
@louthomas4524 Ай бұрын
Dr. Sackner-Bernstein tells us that Parkinson's patients can tolerate a reduction in dopamine, so long as it is gradual. But a gradual decline in dopamine levels is what brings on Parkinson's motor symptoms in the first place, and that is so intolerable that PD patients used to live only a few years before the invention of levodopa therapy. So this claim that a gradual downward adjustment is tolerable, is not credible. The doctor's presentation also seems to imply that if we reduce the toxicity caused by dopamine buildup in the cytosol of dopamine neurons, this will halt or reverse progression. But progression is largely due to auto-inflammatory activity involving innate immune calls called microglia that are triggered to attack by Damage Associated Molecular Patterns (DAMPs), including neuromelanin and aggregated alpha-synuclein, that are dumped into the inter-cellular space when neurons die. Lowering cytosolic dopamine levels will not help with that inflammatory feedback loop and thus will not slow or halt progression. The doctors who told this doctor that his approach will hurt Parkinson's patients are, IMO, correct.
@jonathansackner-bernstein 22 күн бұрын
Published in the Journal of Parkinson's Disease in 2021, I share data showing that while the brain has low dopamine, the spot where dopamine can either function or be toxic - the amount inside the dopaminergic neurons (brain cells controlling movement) is markedly elevated in parkinson's. And in experimental models, reducing that elevated level inside the brain cells results in reversal of disease pathology. Now we need to show whether that benefit also happens in people. The data say this approach is credible and plausible.
@Daft_Ideas Ай бұрын
I think the science is beyond me...I had to look up what the caudate and putamen were...but the info on TH activity rather than amount is interesting.
@Daft_Ideas Ай бұрын
16:08 so dopamine in neuron in a vesicle = good, but dopamine in neuron outside vesicle= bad? So it's a problem of distribution?
@kevinbyrne4538 19 күн бұрын
Apparently. Dopamine in a vesicle is sheltered from enzymes that convert dopamine into harmful substances, whereas dopamine that's not in a vesicle IS converted into harmful substances.
@user-tl5ix8bs5n 17 күн бұрын
Is there any connection between Vertigo and parkinson
@Daft_Ideas 16 күн бұрын
@@user-tl5ix8bs5n a sensation of vertigo can be a symptom of Parkinson's. Could be blood pressure related, but also as your balance is affected by Parkinson's it can simply be down to feeling more "unsteady" or "unsafe" than usual...
@annb5610 Ай бұрын
Went to the Mayo Clinic in Arizona. They ran a test where my serotonin and endorphins were normal and my dopamine was Way High.... Yet they say PD is a lack of Dopamine... .doesn't make sense.... Help!! I ve cut back my carbidopa levodopa.... But when I do none ....I can't move and I'm having trouble breathing 🤔😟 And worse ....no symptoms until the J &J vaccine...which is pulled u the market...I'm only 50
@barbmullen9923 Ай бұрын
I have had PD for at least seven years. I have horrible problems with my balance on the medication. I know from experience that this drug levadopa/carbidopa that I progress much faster with the medication than without it.😢
@grooooved Ай бұрын
Carnivore diet. No more drugs.
@grooooved Ай бұрын
Constipation = too little fat Diarrhea = too much fat ie. Easy to regulate
@isabellefisher8790 29 күн бұрын
I don’t like meat, sadly… Prob why I have PD!
@grooooved 29 күн бұрын
@@isabellefisher8790 Def seems worth looking into. Several reports of full reversal.
@rochellecanova1113 29 күн бұрын
Why do you say that this diet is beneficial? I have not heard this before. Does it reduce tremors?
@pjkkerr 28 күн бұрын
Keto diet improved my PD symptoms. Now trying strict carnivore (lion diet version), still waiting for an effect after only a couple of weeks. Not strictly true, the high fat levels have removed my constipation which is better than nothing.
@viyye Ай бұрын
If the high dose could be harmful, why don't you give people the protocol This guy is here to make money Working for DARPA tells you all you need to know
@brianattig9656 27 күн бұрын
he told the drug name
@belumptuous 25 күн бұрын
Nonsense. He is not trying to make money, he is trying to solve a problem. You don't make big money from a repurposed generic drug, that is why he is struggling to get investors to fund a clinical trial.
@jonathansackner-bernstein 24 күн бұрын
@@belumptuous Thank you.
@viyye 24 күн бұрын
@@brianattig9656 I am 95% sure I have found the medication, it is called Metyrosine
@viyye 17 күн бұрын
@@jonathansackner-bernsteinOK bob, why don't you wanna tell people what the name of the medication is. if your motives were pure then you would help people by telling me
@viyye Ай бұрын
if the drug is out there, just tell people the name of the drug and let people take it
@PeterChenFW Ай бұрын
my P.D, has PROGressed very fast '- a primary dr first suggested I get myself check at around 2000 n I have been confined in a w,heelchaulr for a number of years already
@lisaa6099 Ай бұрын
Really wish you would make 10 min videos. Its far too long