Ed Boyden: A light switch for neurons

Рет қаралды 143,834

13 жыл бұрын

www.ted.com Ed Boyden shows how, by inserting genes for light-sensitive proteins into brain cells, he can selectively activate or de-activate specific neurons with fiber-optic implants. With this unprecedented level of control, he's managed to cure mice of analogs of PTSD and certain forms of blindness. On the horizon: neural prosthetics. Session host Juan Enriquez leads a brief post-talk Q&A.
TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes. Featured speakers have included Al Gore on climate change, Philippe Starck on design, Jill Bolte Taylor on observing her own stroke, Nicholas Negroponte on One Laptop per Child, Jane Goodall on chimpanzees, Bill Gates on malaria and mosquitoes, Pattie Maes on the "Sixth Sense" wearable tech, and "Lost" producer JJ Abrams on the allure of mystery. TED stands for Technology, Entertainment, Design, and TEDTalks cover these topics as well as science, business, development and the arts. Closed captions and translated subtitles in a variety of languages are now available on TED.com, at www.ted.com/translate.

Пікірлер: 265

@liquidminds 13 жыл бұрын

"That might change a couple things"... perfect closing :-)

@dark14cs 13 жыл бұрын

This should be front page news , the implications of this research can not be understated. Bravo

@thisscreensucks 13 жыл бұрын

lol the directors comment at the end of "that might change a couple things" might possibly be the biggest understatement ever uttered

@sunnyy3358 Жыл бұрын

Thank you so much for doing this TED Talk. The amount of scientific progress that could be done with these type of discoveries Ed Boyden is working on is amazing.

@johntheactor 12 жыл бұрын

I like how they mention the singularity in the last minute and a half of the talk like it's nothing.

@feelingfeni4798 4 жыл бұрын

5:20 He said if we could some how GENETICALY MODIFY YOUR NEURONS IN YOUR BRAIN AND EVERY OTHER ORGAN to be a light switch to turn on or off and see what happens to you... Oh wait, he forgot to phrase it in a logistical manner! Oops

@aang7505 5 жыл бұрын

Absolutely amazing! Any updates?? 7 years later??

@KhanRec0rdz 12 жыл бұрын

Holy crap. My jaw dropped when he talked about the eyes! That's revolutionary!

@CheesemanXCV 13 жыл бұрын

Excellent research, excellent opportunities. Extreme need for caution and responsibility.

@VanKlaunch 13 жыл бұрын

Absolutely enlightening and inspiring!

@Lifeintakes 13 жыл бұрын

Great video, thanks TED!

@1a1a1and 13 жыл бұрын

This is sweeeeetttttttttt, loved the q&a ;)

@P00P0STER0US 13 жыл бұрын

Juan was really poking the future with a stick there at the end. Imagine if one could download memories and upload them, either into the same person or another person.

@brianvandenberg4467 6 жыл бұрын

14:30 14:33 wow. How would you get FDA approval right??? !for human subjects..... Claim “Defense Services” Claim “Classified” Surely folks wouldn’t do something like this in the Dark....

@Uraffyouruse 13 жыл бұрын

Great talk

@yaHARmeMATEY 13 жыл бұрын

TED when are u gonna do these in HD!

@oldmcgroin 11 жыл бұрын

This man deserves more respect.

@JoeBrenan 13 жыл бұрын

Just amazing, this is why i study and love science.

@niniomigrania 13 жыл бұрын

Sounds promising! Imagine very complex brain control with this, the possibilities are endless.

@ez910503 13 жыл бұрын

Fabulous. Absolutely fabulous. Perfect marriage of the physics and neurophysiology. Unbelievable.

@nehorlavazapalka 13 жыл бұрын

Am I the only one who sees the potencial of this becoming a torture device? I think that this will be one of it's first applications. It's much more easier to cause pain via this device than to substract memories from the brain.

@13Septem13 13 жыл бұрын

Hope one day I could use technology he talking about for example to learn stuff without reading books but just uploading it into the brain. It is so exciting!

@1schwererziehbar1 13 жыл бұрын

this guy has the most beautiful animations.

@kidmecha 13 жыл бұрын

He is so calm about potentially controlling and/or changing our entire species. I hope he is an optimist (like me) and thinks that (once the technology is in use) we will all be mature enough as a people to use this technology for good and not evil.

@lovrosucic6780 Жыл бұрын

Has your opinion changed in the last 11 years? (Still an optimist) Just curious :D

@deemanrt Жыл бұрын

@@lovrosucic6780 great reply! This is absolutely a control mechanism. Now if only they could find a way to deliver self-assembling nano-tech in a small delivery package that everyone has to accept. Then simply install the lights in key areas and start a pilot programming test. Perhaps they could use large black lights that appear as streetlights? Just speculating here, of course.

@aflamewithintheflame 10 ай бұрын

@@deemanrt haha .... phones are everywhere they would work. all the cameras and 5g ... this is like the matrix but we are walking around... or are we lol.

@rpm297 13 жыл бұрын

I kinda saw the 'download information into the brain' question coming. But how would you or could you teach the human brain to translate binary code, if you could? Would it be more effective than one's own natural curiosity? Could the brain be stimulated in such a way it could send one's learning capacity into hyper-drive? Wouldn't that over-stimulate the neurons and render them into a kind of burnout? More questions than answers for me in this one... must have possibilities...

@Driux 13 жыл бұрын

This talk deserves a standing ovation.

@aflamewithintheflame 10 ай бұрын

for being a complete psychopath yeah

@Driux 10 ай бұрын

@@aflamewithintheflameIgnoring this this is a 12yo comment of mine... That is such an odd thing to reply on two conceivable levels. You think he's a complete psycho for some undisclosed reason. You think he deserves standing ovation for being said complete psycho.

@joeymatee 11 жыл бұрын

that was an amazing talk, i think without dry humour and silly pictures the audience was disappointed

@kablamo9999 13 жыл бұрын

Incredibly interesting!

@AntiProtonBoy 13 жыл бұрын

That blind mouse thing was ace.

@joshliu3964 8 жыл бұрын

This is still works in progress. Ed recently put up an AMA on Reddit. Hopefully psych meds will be a thing of the past

@rabia1180 8 жыл бұрын

can you please link me to the reddit AMA? I looked but can't find it!

@joshliu3964 8 жыл бұрын

www.reddit.com/r/askscience/comments/4ak060/askscience_ama_series_im_ed_boyden_professor_of/

@rabia1180 8 жыл бұрын

Josh L thank you Josh!

@jain355 7 жыл бұрын

TThe Real ED Cure is ovеr 300 Yеars Old! twitter.com/a9c60516d47d92b7a/status/804602507225808896 Ed Bоydeеeen А light switch foor neurоns

@10bristol 3 жыл бұрын

@@jain355 The twitter account is gone. Where can i find the information you talked about?

@9009tubeyou 13 жыл бұрын

Interesting topic he have presented here. Imagine easy learning can be at schools if they had that kind of technology there.

@DeadWhiteButterflies 13 жыл бұрын

Downloading memories. Bladerunner much? :D Great talk though.

@stevenaudet 13 жыл бұрын

This is so scientifically awesome!

@SmushiSan 10 жыл бұрын

Are there any sources for the information he's saying? Can someone help me get his lab journal somewhere?

@NateSonnenfeld 7 жыл бұрын

Just Google Ed Boyden, Karl Deisseroth, etc.Look up their names on Google Scholar, info's all out there.

@elyzavalerio52 4 жыл бұрын

@@NateSonnenfeld kzfaq.info/get/bejne/hMhgard90LCXh6s.html

@MrBranboom 13 жыл бұрын

'That might change a couple things' XD

@libanlibanliban 13 жыл бұрын

Truly amazing.

@brianvandenberg4467 6 жыл бұрын

13:28 14:37 14:40 part of my #ivXXX Protocol.....the Eye Tracking “Software” Portion. M EYE 👁 Algorithms that learn to activate switches with single commands (Private Internal Voice Vibration Protocol 2cd edition). Look at a switch/Relay and say “On”...Receiver activates!!! All this 3 second delay....with “Hey Alexa” or “Hey Siri” going obsolete in 5 years..... What channelRhodOpsin will you pick?

@test123ok 13 жыл бұрын

this is fantastic ! I can't wait till this becomes a real product.

@LaBambathereal 13 жыл бұрын

i have always wondered... how does our body make electrical impulses ? There's no power supply, or is there ? Do we make some kind of biotic electricity ?

@SkiesAhoy 13 жыл бұрын

@andy3071190 Noise that you have to endure? Oh please. There's a very obvious mute button which you can use for those few seconds, if the starting music is really THAT aggravating.

@t3tsuyaguy1 13 жыл бұрын

@Ultra4 In it's simplest form, it's essentially a domino effect. One pair of sodium & potassium ions switch positions. This leads to a change reaction down the length of the neuron. Think of sports fans doing "the wave". Of course it's more complicated than that, but it's a common enough way of explaining the action of neural impulses.

@aang7505 5 жыл бұрын

Phenomenal!

@yaHARmeMATEY 13 жыл бұрын

@cristoretornebiblia then dont choose the HD options then :S

@TerielAtmano 13 жыл бұрын

Wow. Now THAT are ideas worth spreading.

@t3tsuyaguy1 13 жыл бұрын

Very clever.

@Phyrexious 13 жыл бұрын

Madness..? THIS IS... AWESOME!!!!

@Redflowers9 11 жыл бұрын

Ed Boyden was a *prodigy actually, he worked for MIT as a teenager.

@Ko252 13 жыл бұрын

This is genius.

@Desert2GardenLV 13 жыл бұрын

Someone please give this guy a Billion dollars. We need this.

@damoninsky 13 жыл бұрын

@Icecoldpoker I think there should be science on every front-page. People need to pay attention and be more involved in its advancement. We should celebrate the incremental breakthroughs and build more confidence to lead us to bigger breakthroughs (such as vaccines, technologies, discoveries...not disappointments).

@ngarcia257 13 жыл бұрын

This is awesome... And this needs more views...

@MrPlatonist 13 жыл бұрын

@volound in that sense, yeah. but the way YOU said it, it seemed otherwise. iow, probably my mistake then. =)

@bryanm6080 3 жыл бұрын

Anyone here in 2020 based off of Neuralink? Was looking at professors to start a masters in neuroengineering, came to search for Dr. Boyden @ MIT!!

@YourCritic 13 жыл бұрын

Brilliant

@P00P0STER0US 13 жыл бұрын

@SheepRCool17 What need? We already have television, radio, cheap food, fatigue, and myriad other elements to keep us doing what we're expected to do. The idea of a physical implant used for that seems clunky. I think it's truly marvelous if such things can help people afflicted in such a way that this can help.

@maxgunn555 13 жыл бұрын

@TheFounderUtopia how is it ironic i dont understand?

@Spencerianism 13 жыл бұрын

@maxgunn555 How old are you?

@nehorlavazapalka 13 жыл бұрын

@hmspinaforethisisspa 100% sure that you are right.... but this can really become the worst torture ever

@Rarae192 12 жыл бұрын

@andy3071190 I love that noise: bwwwwoaaaaaONGGGGGG!!! It wouldn't be a TEDTalk without it.

@oicub2 13 жыл бұрын

@shade1978x 17:12 That does change things don't it ..

@MrBalcora 13 жыл бұрын

If this research is successful, it will definitely change society

@FungusyHam 13 жыл бұрын

woah, I read this in scientific american a couple of months ago. Cool stuff!

@t3tsuyaguy1 13 жыл бұрын

@belliebum12 LOL! Actually, they'll probably need programmers to write the interfacing software. You'll have plenty of work. ;)

@charlesedwards5816 3 жыл бұрын

nice

@ianmathwiz7 12 жыл бұрын

3:19 Migraines must be twice as common, seeing as they're listed twice :D

@andreeaweed 12 жыл бұрын

wow this is a great invention ...this is a genius

@Decimaster321 13 жыл бұрын

The evolutionary developments that lead to the growth of neurology must have been amazing, producing a system that seems so far removed from basic chemical survival. I wonder if we will find out how these cell systems emerged in my lifetime.

@vqly 13 жыл бұрын

@Dixavd It's more than fine, every time that mouse get a jolt of blue light it's feeling a jolt of dopamine, the brain reward system.

@ChrisCapel 13 жыл бұрын

@abram730 Oops, yeah I meant Parkinsons... Soooo yeah...

@Dixavd 13 жыл бұрын

@vqly yes I know, I understand it perfectly and every way it works and the fact that the mouse gets pleasure from the blue light but just like irrational phobias I can't help but feel uncomfortable when I see it connected to that thing because of allt he times I have been in hospital in my life with drips and canulae and things so anything being connected to an alive awake subject - thanks for trying though.

@ErichoTTA 13 жыл бұрын

I admit the name "Siemens" sounds funny.

@maxgunn555 13 жыл бұрын

@TheFounderUtopia what makes his name ironic?

@nightmathzombieethan 13 жыл бұрын

Cool, AND scary.

@holdmybeer 13 жыл бұрын

kind of scary O.o but important also.

@DeanOSupremo32 13 жыл бұрын

Man so much good can come from this...but also evil

@Volound 13 жыл бұрын

@MrPlatonist they do, actually. understanding my position and my arguments is a prerequisite for being able to think about them. isnt that obvious? but if you mean it literally, then i didnt make any such accusation, so strawman.

@cronnyberg 13 жыл бұрын

This can have so many amazing applications from curing sensory ailments to mental disorders, downloading binary information directly into the brain and even emotional manipulation (it could even lead to mind control lol!!!) It is only limited by our understanding of the human mind, which is ironic, because it could also be one of the foremost developments into studying the human mind too :D truly incredible!!

@borderlinebuddhist 13 жыл бұрын

i find it depressing that this isnt front page news.

@ZeusLT 13 жыл бұрын

@saurabhdelft to serve us

@Lostpanda123 13 жыл бұрын

@juanarruti Thats true :D

@epicbrowndragon Жыл бұрын

Studied for 11 years…this then aired 11 years ago…and 11 years later what tech do we have using this?

@tunnis7us 13 жыл бұрын

Finally good ted talk without stupid time consuming jokes in every sentence

@GiffyPooh 13 жыл бұрын

Today I graduate with a Masters degree in Psychological Counseling... and I guess it's also the same day I change professions.

@matrixistrue 13 жыл бұрын

@Driux AMEN BROTHER

@roidroid 13 жыл бұрын

@Th3CrimsnChin so deep

@kiddhitta 13 жыл бұрын

@borderlinebuddhist well then there would be no room for the new episode of Glee's advertisement

@rlinfinity 13 жыл бұрын

@madzane94 Alga is singular. Algae is plural.

@SyllonRM 13 жыл бұрын

the guy talking is extremely nervous =D

@nicolareddwoodd7377 10 жыл бұрын

I am so sorry, mouse.

@paulathebomb2 9 жыл бұрын

Nicola Reddwoodd They are doing this with foster children, making them to forget thier families and where they came from to adopt them out for money. God help us. Reply ·

@luiseguez8175 11 жыл бұрын

oh my god

@thormayer 13 жыл бұрын

Singularity is near :)

@Jotto999 13 жыл бұрын

Neurology and genomics will transform humanity!

@browntown72 13 жыл бұрын

@t3tsuyaguy1 lol yeah i meant it in a sense that "despite this breakthrough, the harsh reality is that this research will not be available to all". But yes, exactly, i was just expressing my frustation at the fact that brilliant research like this, or recent breakthroughs in cancer treatment ect. are not employed because it doesnt provide the biggest profit. I agree with that assertation, but i believe that fear is used to make money. Without money, they wouldnt need to cause fear.

@madpuri 13 жыл бұрын

@TupoyVolk Arts, Music

@consciousnez 12 жыл бұрын

I cant wait to genetically modify my children...i wasnt even gona have kids till i saw this. now i will have super kids

@jjk2one 6 жыл бұрын

They will murder their parents.

@arie1899 6 жыл бұрын

Actually with no technology, they murder their parents...

@jjk2one 3 жыл бұрын

@@arie1899 Blade runner murdered his girl friend... figure it out if you can

@1993whitenoise 12 жыл бұрын

Only 31 thousane views... And a lil wayne video has how many?? Show me the justice in that...

@Volound 13 жыл бұрын

@saurabhdelft i disagree. i think that anyone i asked would realize my response addressed your argument and blew it out of the water. it shows you are just arguing from ignorance. and theres a certain kind of irony to someone accusing someone of being a "shallow thinker" who hasnt managed to grasp all of the rudiments of the english language, wouldnt you agree? but to answer your question, "what was the goal of black people, what was the purpose of black people in 1850 in the americas"?

@redsbr 13 жыл бұрын

If even NOW one's "ability to learn" and one's "intelligence" is controlled by money, how does that shape our perception of the value of one's life. Will we let the market decide who is more valuable, the ones who can afford such enhancements? Or will we finally admit that all life, the smart and dumb, the strong and weak, the big and small, and the fast and slow... all life has INTRINSIC and EQUAL value. What will you decide, as we soon manipulate the most sanctic parts of ourselves?

@Redflowers9 12 жыл бұрын

It's great when child prodigies actually go on to be productive.