So many people think “cholesterol” is a disease. I hope this helps to start break that incorrect paradigm.
@DBLBx6 ай бұрын
When i was in horrible metabolic and physical shape my TC was just under 200. My HDL was below normal and triglycerides were through the roof. My doctor never said a word. I dropped 50lbs via IF and extremely low carb. My LDL and HDL shot up to 347/72. Triglycerides dropped from 200+ to 93. My doctor completely freaked out and wanted me on statins... NEGATIVE...i have never looked back.
@Joe_Blo4 ай бұрын
You avoided certain future doom.
@westfield907 ай бұрын
What a great telling moment that will likely be ignored by most of establishment medicine. We’ve been handing out statins for almost 50 years like candy and yet heart disease remains the number one killer.
@nicknorwitzPhD7 ай бұрын
I can tell you from the inside... definitely not getting ignored, LOL!
@meatdog7 ай бұрын
People need to lean the word "NO" and use it with their PCP. Until that happens prople woll continue to be lemmings and have bad outcomes from blindly taking these very harmful stating drugs, among others. Americans are incredibly IGNORANT and want a pill for everything. The visit to the PCP isn't for health, it's for a prescription. I know because I retired from practice because I couldn't do that anymore. I hated every time someone threatened me if I told them they didn't need a pill for their issue.
@porkpie28847 ай бұрын
We need a whole lot more to ignore it though Nick, but keep up the good work. Neither cholesterol nor lipoproteins cause disease @@nicknorwitzPhD
@irenalovesart40647 ай бұрын
I'm at a stage where my parents and in laws are all on statins. How could you convince them that low fat high carb is the problem???
@irenalovesart40647 ай бұрын
And drinking I bet
@bobeldredge2827 ай бұрын
Maybe if someone has high LDL they should get a CAC score and find out if they have CVD first? Instead of throwing a drug at them!
@bobeldredge2827 ай бұрын
Very interesting thanks for sharing, I've been ketovore for 7 years, former T2D a1c from 13.3 to 5.1, 255 lbs to 175 (now 185) that's my why. Seems I always have a elevated LDL and yes they always want me to leave the office with a statin, (67 years young)
@chuckleezodiac247 ай бұрын
that ain't in the Sacred Protocols of the Medico-Pharma Industrial Complex.
A doctor taking the time to establish an actual disease as opposed to prescribing a drug based on an outdated lipid concept? That's crazy talk!
@nataliajimenez18707 ай бұрын
@@Beatrice-nx5ldYou can do a CT angiogram to detect the soft plaque. But having a CAC score of 0 at your age is highly correlated to very low risk of atherosclerosis. You can repeat the CAC test every couple of years to reassure your physician
@amfohr7 ай бұрын
Brilliant action by Nick, to boldly go where no one has gone before!
@loadsamoney-u3x7 ай бұрын
@amfohr You are completely wrong. It seems that you are not well-educated enough to realize that this PhD student is simply discussing things that academics like myself already know. Please get a book on basic human biology and chemistry before you praise a very new PhD recipient.
@amfohr7 ай бұрын
@@loadsamoney-u3x What 'things' did you already know John, can you be a bit more specific? I mean, that is something I can ask of a well-educated person I hope?
@loadsamoney-u3x7 ай бұрын
@@amfohr Well the whole situation of Nick being on media talking like he has discovered something new is quite frankly comical and very dishonest, obviously he just hopes to get exposure for himself and his channel,now all the health and low carb youtube gurus will jump on the Oreo lowers LDL train to gain subscribers but normal people will be even more confused and that's what these KZfaqrs love doing,they love confusion because it makes them money making videos. While his revelations may seem less groundbreaking to those well-versed in our field, it is crucial to elucidate the biochemical intricacies at play. Fundamentally, in the absence of a threshold glucose intake typically 100-130 grams a day, glycogen stores deplete, prompting the liver to initiate gluconeogenesis, mobilizing fat for energy. This metabolic shift elevates LDL levels, acting as metaphorical garbage trucks transporting surplus oxidized particles to the liver. Conversely, reintroducing carbohydrates/Glucose ie "Oreos" replenishes glycogen stores, leading to a decline in LDL levels,his therefore fooling no one in academic circles only very uneducated people on youtube. This dynamic interplay underscores the importance of discerning the nuanced relationship between dietary choices and metabolic responses, dispelling the notion of Mr. Norwitz's revelations as irrelevant and highlighting the evolutionary significance of glycogen storage in the liver. Nature has chosen to give the liver an opportunity to store Glycogen for a fast fuel for muscles to enable quick reactions(fight or flight)autonomic reactions without that gluconeogenesis in the form of fat conversion may not fully supply that need,the fact is people are overloading on simple sugars and carbohydrates,when we only really function 100% on what our livers store ie 100-130 grams per day,its the carbohydrate /glucose over load that makes red blood cells saturated and therefore causes heart disease,CV disease and obesity.
@amfohr7 ай бұрын
@@loadsamoney-u3x Fair enough, I don't find it confusing tbh, he also might have taken a banana or a sweet potato to get the same effect. The point was more to compare the effect of reintroducing some carbohydrates with a statin, what doctors usually tend to prescribe. The point is that reintroducing some carbs is more effective and without the downside of statins.
@amfohr7 ай бұрын
@@loadsamoney-u3x You write that a "carbohydrate /glucose over load makes red blood cells saturated and therefore causes heart disease,CV disease and obesity." If that is so well known then WHY ARE PEOPLE NOT EDUCATED ABOUT THAT?! 70% of Americans seem metabolic unhealthy. Finally what is your opinion on elevated LDL on a high fat low carb diet, that is elevated LDL caused by low glycogen storage? Does it increase risk for CVD? Since you specifically mention it in regard to carbohydrate /glucose over load.
@mbrochh827 ай бұрын
Here's a ChatGPT summary: - Harvard Med student and scientist Nick Norwitz lowered his cholesterol with Oreo cookies while following a ketogenic diet. - The experiment aimed to test the lipid energy model and the concept of the lean mass hyper-responder. - Lean mass hyper-responders are individuals on a ketogenic diet who are lean and have high LDL cholesterol but good metabolic health. - The lipid energy model suggests that LDL and VLDL are used to traffic triglycerides for energy, leading to high LDL levels in some individuals. - Norwitz conducted a crossover trial on himself, comparing the effects of Oreo cookies to high-dose statin therapy on his LDL levels. - The trial was conducted with appropriate IRB ethics, support from his PCP, and a consultant cardiologist. - Oreos lowered Norwitz's LDL from 384 to 111 in 16 days, a 71% drop, which was twice as effective as the statin therapy. - The experiment was not intended as a health intervention but as a metabolic demonstration. - The findings are meant to provoke conversation and scientific curiosity, not to suggest that Oreo cookies are healthy. - Norwitz experienced emotional lability and discomfort during the Oreo phase, indicating a negative impact on his well-being. - The study aims to encourage further research into the lipid energy model and lean mass hyper-responders. - Norwitz hopes the study will not be misinterpreted to promote unhealthy eating habits. - The study highlights the need for more research on the specific population of lean mass hyper-responders and their cardiovascular risk. - Main message: The experiment with Oreo cookies was a dramatic demonstration to test a scientific model and provoke discussion, not a recommendation for dietary practices.
@shiplesp7 ай бұрын
Are you forgetting the sugary processed breakfast cereals that show up as highly recommended in the Tufts generated food rating guide? It would not surprise me to discover Oreos high up on that list.
@nataliajimenez18707 ай бұрын
Yeah, when you read the comments left by vegans on the Plant Chompers interview with Nick they are using it to justify their hatred of meat-based diets and saying that even the worst carbs are better than animal protein/fats. I think that this is useful for those doing keto that are concerned by their super high LDL (>300) and get bad side-effects from statins. It can even be helpful for those that want to quickly reduce their LDL for insurance purposes. Also let's remember that Nick is not the only person that has reported this effect. Dr Tro published last year a series of case studies showing that adding 50-100 g of carbs through sweet potatoes to 5 of his LMHR patients lowered greatly their LDL
@carnivorehippie80717 ай бұрын
They did, in fact, list chocolate chip cookies as "healthier" than ground beef. Specifically cookies were rated as acceptable in moderation, while ground beef was recommended to be completely avoided.
@petermadany27796 ай бұрын
If I were forced to eat some junk food to lower my LDL, I would choose Romney’s Kendal mint cake, since it’s almost pure glucose. The ingredients list for Oreos is disgusting. 🤮 🤢
@KenJackson_US7 ай бұрын
My doctor said since I refuse to take a statin there's no reason for him to even order a lipid panel blood test. I said "OK". But later I realized, wow! That was a tacit admission that he ONLY looks for opportunities to sell drugs, not for problems in my health.
@SydneyCollin7 ай бұрын
Yep. Most doctors are legalized drug pushers.
@johnow77 ай бұрын
If you don't know, you can get an NMR lipid panel done with a doctor's order. It will give basic information and the composition of your lipid particles.
@KenJackson_US7 ай бұрын
@@johnow7: _"you can get an NMR lipid panel"_ Yes, I could. But as my former doctor explained, he couldn't justify asking for it for diagnosis, so I would have to pay for it. I decided I didn't want it bad enough to pay for it. My goal is to see a doctor as little as possible. This new doctor's goal seems to be to see as little of patients as possible that he can't pump full of drugs. So I guess we're right for each other.
@johnow77 ай бұрын
@@KenJackson_US I get the basic lipid panel paid for and pay out of pocket for the NMR. I diet carnivore/ketovore, mostly carnivore. I personally wouldn't dream of proceeding with this diet without regular blood work. For most of the first year on this diet, my triglycerides shot way up. I had to change my eating habits on the diet to bring them down. Who knows the long term damage I could have done had I blown off labs. I don't believe that one diet fits all and I use my labs as an indicator that the diet I have chosen is working for me.
@KenJackson_US7 ай бұрын
@@johnow7 My understanding is that carbs, especially sugar causes triglycerides. I saw my roughly yearly lipid panel markers improve in the first three and a half years of keto, so I'm not concerned. I don't even prick my finger for glucose any more. Keto shouldn't be too complicated. I'm just staying the course, trending toward carnivore. My concern is thyroid. Why the heck am I hypothyroid? I pulled teeth to get this doctor to order the thyroid antibody tests and found that they're very high. Great. Now I know for sure that I have Hashimoto disease. Didn't know before. So I'm making progress.
@labynoe7 ай бұрын
I’m convinced ALL humans were what we would today label as “Lean Mass Hyper-Responders” for the 99.6% of our 2 million year existence prior to our invention of agriculture. The dietary pattern available to hunter-gatherers would be expected to produce higher cholesterol levels compared to that produced on the plant-based, high PUFA vegetable seed oil, high carbohydrate dietary pattern which was already the dominant dietary pattern when we began measuring cholesterol levels back in 1955. I believe if there were a “fossil record” of human cholesterol levels, it would show far HIGHER levels than what we currently label as “hypercholesterolemia”.
@biodivers52947 ай бұрын
Being curious is the base of science. Your findings are forcing us to think better about how certain people react to certain foods, and what that means for health. Great!
@annacourville46227 ай бұрын
As a LMHR myself, thank you for pushing the science. I was told to see a cardiologist. Nope.
@BeefNEggs0576 ай бұрын
Wouldn’t hurt to get a CAC at time 1 and time 2 and see how you’re doing. But if you’re like me and don’t plan on changing my diet anyway then F it. If you feel good you are good. I don’t think any diet matters that much. Avoiding diabetes, dementia, frailty and obesity is #1. That rules out all cholesterol meds. Meat and eggs.
@zachary8136 ай бұрын
@@BeefNEggs057 My Kaiser doctor wanted me to take a statin but refused to give me a CAC. I think of him as an insurance adjuster and drug pusher, not a doctor.
@lilanlim48296 ай бұрын
Some doctors are drug agent😁
@carnivorehippie80717 ай бұрын
The genuine evidence indicates that high LDL in and of itself is NOT invariably dangerous. It is part of a milieu which must be evaluated as a whole. Unfortunately most medical professionals come nowhere near understanding the nuance.
@timothyblazer17496 ай бұрын
High LDL is not causal. It's a part of the biochemical equation, but isn't indicative of disease. Biopsies of atherosclerotic plaques, for example, contain a small amount of LDL particles. However those biopsies showed staggeringly large amounts of campesterols. Since that is essentially a plant sterol, and could only get there via seed oils, that huge result has been ignored, and all focus is on the presence of tiny amounts of LDL, Not even mentioning campesterols, or that those plaques are primarily composed of scar tissue.
@jimlofts54337 ай бұрын
does this channel have a discount code for Oreos - asking for a friend
@jaymehatfield95407 ай бұрын
That was pretty dang funny. Thanks
@nwobob7 ай бұрын
The purpose is to create some cognitive dissonance in the halls of academia.
@JohnSmith-zs1bf7 ай бұрын
It's not to question the oreo safety but to question the LDL safety
@rumproast51597 ай бұрын
In my simple mind this study tells me your body knows what it’s doing. Feed it well….high LDL= healthy, feed it poorly ……low LDL= unhealthy.
@Sobchak27 ай бұрын
@@rumproast5159that’s exactly the problem with these stunts: many completely misunderstand the meaning of the results.
@rumproast51597 ай бұрын
@@Sobchak2 so…..what’s your takeaway from the stunt. Saturating the liver with sugar lowers LDL. I guess I assume wrongly that most people know medications poison a normal pathway in the body. Somehow statins mimic saturating the liver with glucose but not as well as the real deal. Or somehow interferes with the LDL cycle. My takeaway is to continue limiting refined sugars from the diet. Not the reverse.
@Sobchak27 ай бұрын
@@rumproast5159 in this individual, who follows a high fat ketogenic diet, leaving a state of ketosis resulted in a significant drop of LDL-C levels. "Saturating the liver" doesn't mean anything. With statins you have two contrasting effects: one that keeps pushing your LDL-C levels over the rooftop, and the other, the statin, which reduces the endogenous synthesis of cholesterol. Statins are hmg-coenzyme A reductase inhibitors, and by mimicking the structure of an intermediate in the biosynthesis of cholesterol they prevent its synthesis, mostly in the liver. They have nothing to do with sugars.
@Milana_Kay7 ай бұрын
Awesome interview! I can so relate to *male period*. Since I went keto my actual female periods have evened out so much that I barely notice them. But I also realized that my mood wasn't only fluctuating through out the month but also sooo much through out the day. None of that now.
@methanial737 ай бұрын
Oreos: the newest drug craze.
@jamesbarksdale9786 ай бұрын
😂
@bobfoster6876 ай бұрын
OTC!
@zombieapocalypse38375 ай бұрын
Get ready for the Oreos price to go up.
@dianechilds18577 ай бұрын
I was hoping Nick would have a NMR test before and after. Did his LDL particles change size?
@BeefNEggs0576 ай бұрын
Without arterial lining damage who cares what the particle size is. But yeah that would be important to the particle size matters crowd.
@clovermark397 ай бұрын
This is something I’m going to introduce to my Dr who is pushing me to take statins and also the specialist cholesterol clinic which I will eventually go to. They say it’s bad to have high cholesterol and needs urgent treatment but it’s like 9 months wait now for an appointment in the UK to see a specialist so not that urgent imo.
@davidgmillsatty19007 ай бұрын
See B. Forette, et al Lancet 1989. “ Overall mortality was lowest at serum cholesterol at 270 mm.
@args504517 ай бұрын
I've had a heart attack and have 3 stents as a result, I have to believe that the human body when fed a natural whole food diet will heal itself. As far as I can tell all disease is caused by systemic inflammation and is the cause of 95% of all disease (including CVD). The inflammation is caused by diet. This experiment would not work the same on a person following the SAD.
@ambrosiofamily69027 ай бұрын
Love his ingenuity and grit.
@LivingTheLifeRetired7 ай бұрын
My two favorite guys. Excellent discussion.
@nicknorwitzPhD7 ай бұрын
@josephfeeney80757 ай бұрын
your provocative presentation has lifted my spirits.L'm tired of being vilified by drug oriented health providers
@jobrown81467 ай бұрын
I used to love tinned beetroot. After I remitted my diabetes by going low carb I decided to treat myself to some beetroot just for something different. I no longer liked it. However when I treated myself to some kiwi fruit (a tray of 5 or 6), they were very yummy but I was satisfied with only having one each day whereas before low carb I probably would have eating two at a time. I am also noticing that there are certain levels of sweetness of foods (sweetened with stevia) that make me want to keep eating them. I have made my own chocolate with coconut oil and cocoa powder with the second batch have double the amount of sweetener and I found it hard to stop eating it.
@jamesdellaneve90057 ай бұрын
Yes. That’s food addiction. Sugar triggers our opiate sensors. Kelly Hogan, long time carnivore had the same problem and only carnivore fixed it.
@T-aka-T7 ай бұрын
It's not quite clear (to me) what you're saying here - beetroot is very sweet, kiwis are mostly acid to the point of disguising the sugar (like lemons) - except for golden kiwis (really sweet, less tartness from acidity). So I kinda get what you're saying, but not certain. ( As a carni, I can now taste very clearly a 0,.6,% sugar content in ham - it tastes disgustingly sweet. I haven't had beetroot in a while, but I used to like it (and prefer green kiwis to gold ones). So in my case, my senses are heightened, and sugar revolts me. Are you saying you still like it? Anyway, cheers! 😊
@jobrown81467 ай бұрын
@@T-aka-T I'm noticing that there are foods that I used to like that I no longer find as enjoyable. Since changing to low carb my tastes have changed. I regularly make myself a mug cake and I started using 1 1/2 Tbl of sweetener, then found that too sweet and cut down to 1 and a bit and now I'm only using 1 Tbl. I've also started being very aware of what foods/sweetness level makes me want to eat more of that item.
@T-aka-T7 ай бұрын
@@jobrown8146 Has your sense of smell got very keen as well? I smell things now that others can't. Also, I pick up mail from a post office opposite a Red Rooster chicken place - the stench of (I suppose oxidised) seed oils is revolting - same with fish & chip shops etc. I can't IMAGINE how I once thought fried chips would be nice to eat. Interesting shifts we experience, eh?
@jobrown81467 ай бұрын
@@T-aka-T I've always had a strong sense of smell, especially of artificial smells (I think they contain smell enhancers like food has MSG a flavour enhancer) and can smell neighbour's washing on their clothes line (1/5 acre block of land in Australia), and car scents when I'm in car parks and people open their car doors. Yes, it is interesting the shifts we experience. Mine is more of a mental thing where now when I see food I think in terms of how much sugar/carbs is in it. Before I would look at items in the grocery store and think in terms of how yummy I could remember them being but because I am more educated now it not how something tastes but how it is going to affect me. I'm going to be having ground beef with eggs mixed in for my dinner tonight with zucchini. Looking forward to it.
@stephensimon76217 ай бұрын
the point you guys are mising is the LMHR studies shows that LDL is not the independent varisble it is thought to be. for example it might be more important to how the LDL is lowered than that it was lowered. We need to reopen the research and quit the LDL is bad. most docs are lazy.
@petercyr35087 ай бұрын
Wow Mondelez International (not Nabisco anymore) needs to apply for that Heart Healthy label for their concoction of seed oils and sugar.
@T-aka-T7 ай бұрын
Refer them to Tufts. They advertise for industry "partners" on their home page. In effect, "please send money. We have proved our carby bona fide. "
@efsmiley19957 ай бұрын
That's what is going to happen I predict. The research has to move forward now. It just does. Anyone that tries to discredit this demonstration or the LMHR studies will down the road look ridiculous for doing so. I can't wait! I mean for the results of the upcoming studies and the conclusion of the LMHR study. Not for the critics looking ridiculous.
@davidgifford81127 ай бұрын
The medical profession and big pharma’ have been doubling down on some pretty insubstantial data (but loads of it) to support the Lipid Heart Hypothesis for decades. They will not go down without a massive fight. This and any follow-on studies will be ignored or ridiculed for a long time to come. The dogma-driven main stream medics will respond thus: “this is exactly what we would have expected. This proves keto, very low carb’ diets, elevate LDL (the bad cholesterol), even cookies are healthier than a ketogenic diet. A study of only 4.7-years isn’t long enough to show the convincing progression of atherosclerosis as CAD is a function of both high LDL (high ApoB) and exposure time.”
@nicknorwitzPhD7 ай бұрын
I tend to agree...
@carnivorehippie80717 ай бұрын
Well, I, for one, am totally looking forward to some of the critics looking ridiculous.
@efsmiley19957 ай бұрын
@@carnivorehippie8071 😂
@johnow77 ай бұрын
I read some of the comments of Nick's discussion with Dr. Willett on the Plant Chompers channel. Their are still people their insisting the cholesterol and saturated fat causes heart disease. I think that it will take decades to change the paradigm.
@bobeldredge2827 ай бұрын
I always knew oreo's were healthy 😮 Thanks Bob the welder
@NoName-cx3gk7 ай бұрын
@@250txc This was a JOKE
@jamesdellaneve90057 ай бұрын
As if we needed a study confirming this! Pffft!
@manekedark6 ай бұрын
This study was not paid by oreo, trust me dude.
@bobeldredge2826 ай бұрын
@@manekedark it was a joke!
@ekondigg67517 ай бұрын
Why would anyone want to reduce the amount of Low Density Lipoprotein nutrient transporters in the first place? The liver makes them for a reason: to transport nutrients. Guess what happens if that is artificially reduced...
@kevinalanmattson7 ай бұрын
IMHO, Dear Norwitz and Feldman,, et al. >>>To get through to lay people, please explain these two items carefully each time: 1. LMHR's, and how they are like genetically engineered mice which allow us to study particular effects. AND 2. What exactly is the Lipid Energy Model. I hear "LMHR" and "Lipid Energy Model" glossed over in every discussion on this subject. It has taken me at least 10 KZfaq vids on this topic to understand the LEM, and why LMHR are ideal for the experiment you did and the the related papers recently published.
@YouTw1tFace7 ай бұрын
Can you explain?
@T-aka-T7 ай бұрын
Did you good to do some of your own research and now you're really across it, right? 😊
@flowrider50826 ай бұрын
That’s the way the cookies crumble! 🤣😇❤️🇨🇦
@veronicaheaney34646 ай бұрын
So glad YOU did this! I would have gagged trying to eat that many cookies per day, not to mention the response in my blood sugar level.
@kevanhess21057 ай бұрын
Thank Goodness there are Doctors like uou guy's. 🎉
@christinekinn61786 ай бұрын
I applaud you for having the courage to be provocative. Some others have asked about if you tracked your blood sugars. Would it have been informative to also track your insulin levels?
@slowbaker7 ай бұрын
Like Nick, I have high LDL, low triglycerides, high HDL low BMI, a1c of 5.2. Been on a ketovore diet for almost two years. 73 years old. Where should I get health advice from? My cardiologist fights me every year to take a statin. I took them for years, but got off of them two years ago. Total cholesterol is in low 400s.
@davidgmillsatty19007 ай бұрын
Dr Cyves has a good podcast on lean mass hyper responders, particularly Dr. Paul Saladino. LDL comes down very rapidly on about 50 g of carbs a day if I recall. Saladino chose to eat fruit. But the video will help. It is recent. In the last couple of months.
@slowbaker7 ай бұрын
@@davidgmillsatty1900 Thank you! I'll look it up and watch.
@loadsamoney-u3x7 ай бұрын
@Metabolic Mind As an academic specializing in human biology and chemistry, I feel compelled to address the recent discourse initiated by Mr. Norwitz. While his revelations may seem less groundbreaking to those well-versed in our field, it is crucial to elucidate the biochemical intricacies at play. Fundamentally, in the absence of a threshold carbohydrate intake, glycogen stores deplete, prompting the liver to initiate gluconeogenesis, mobilizing fat for energy. This metabolic shift elevates LDL levels, acting as metaphorical garbage trucks transporting surplus oxidized particles to the liver. Conversely, reintroducing carbohydrates replenishes glycogen stores, leading to a decline in LDL levels. This dynamic interplay underscores the importance of discerning the nuanced relationship between dietary choices and metabolic responses, dispelling the notion of Mr. Norwitz's revelations as irrelevant and highlighting the evolutionary significance of glycogen storage in the liver.
@m.p.60397 ай бұрын
I can't wait to see the next Oreo commercials.
@UnknownUser-sc6jx6 ай бұрын
Keto has almost cured me of anxiety and PTSD. The side effect seems to be it fixed my ADD as well my focus and concentration is 100% better.
@metabolicmind6 ай бұрын
Please email us at info@metabolicmind.org if you are interested in sharing your story. Congratulations on your success!
@duanekeith78167 ай бұрын
I recall reading 20 or more years ago -- having no citation because I don't feel like researching what might since have been hidden -- that for every five percentage points that pharmaceutical companies insisted that LDL must be lowered, the industry generated a billion bucks. Could the emotional roller coaster have been related to a blood glucose roller coaster? The magnitude of the BG roller coaster does not have to be huge in order to generate effect.
@pointshealthcoaching84747 ай бұрын
If general practitioners don't buy in..... it won't help me, nor others... if you believe this phenotype is so rare, then doctors who hardly ever see this phenotype won't give a ....
@kenadams55045 ай бұрын
My Doc saw my ldl hyper response from my keto diet, intermittant Fasting and daily cardio .He tried to statin-ise me .I then learned that I have the Triad of lipids , low bmi and pre-keto normal ldl amounts .... fulfilling the " lean mass hyper response " criteria . I may go back to my Doc in 2 weeks with 'normal' ldl amounts and tell him I just ate a packet of oreos each day, (just to see the expression on his face ).
@il3mendo7 ай бұрын
You should have test: hdl, homocisteine and fasting insulin
@johnow77 ай бұрын
He did test HDL. It went up.
@il3mendo7 ай бұрын
@@johnow7 vldl ? Really strange that hdl went up with this type of product. Thanks
@johnow77 ай бұрын
@@il3mendo Well he was already doing keto. He just added the Oreos to it.
@il3mendo7 ай бұрын
@@johnow7 It seems that his metabolic health is really good. Last time when I reintroduced complex carb my glucose level reached 250. I am metabolic compromized due to some illnessess. Thank you
@margaretgibbs10077 ай бұрын
So what would happen with a metabolically UNHEALTHY person on SAD with high LDL, consuming Oreo cookies?
@Pinkorchid727 ай бұрын
That’s the next test. This is just the beginning.
@jobrown81467 ай бұрын
My thought: their trigs would go up and their HDL go down. No thoughts on the LDL though.
@anikachatziioannidou63007 ай бұрын
They would become even more metabolically UNHEALTHY, it’s the easiest prediction to make
@stargazerbird7 ай бұрын
Nothing. They are already eating that many grams of carbs.
@T-aka-T7 ай бұрын
Myocardial infarction? Or - just another couple of kilos of visceral fat in waiting. I want to add a grinning face here but it seems kinda churlish / Schadenfreude. Oh, what the heck. 😁
@firstchoicefarm77672 ай бұрын
Nick was not correct in thinking there was a possibility of the media would pick this up. An extreme percentage of advertising revenue is from the pharmaceutical industry. They heavily influence the news. Robert Kennedy has shared his story regarding this.
@minette7477 ай бұрын
Interesting. My LDL was really up being on keto and low carb. I added extra carbs in my diet and my next LDL test showed it went down. It was really strange that carbs can decrease the cholesterol. This reminds me of eating oatmeal can lower cholesterol. The real issue is for how long it can do it or if there is a ceiling for carbs to do that. Also this may demonstrate lowering LDL but may affect the triglycerides negatively.
@timothyblazer17496 ай бұрын
Please do not eat mixed carbs and fats! This could disrupt the Randle cycle in your cells, creating high blood glucose and causing damage to many systems. LDL has never once been causally linked to atherosclerosis, regardless of what the medical establishment keeps pushing.
@MichaelGGarry6 ай бұрын
Maybe stop eating Keto - which is crap?
@timothyblazer17496 ай бұрын
@@MichaelGGarry no, that's gorillas. They eat their crap. We don't. We eat the way our ancestors did. Meat.
@FarideLadak7 ай бұрын
So the next steps in this research are to test it for a longer period of time. Possibly in six weeks periods with the Oreos, is it an anomaly? Or a possible solution for many? Etc.., Thank you
@6stringcodger4506 ай бұрын
It’s a prank! Doctors and academics have known for decades that switching from low carb no-carb diet to higher carb will drop cholesterol for many. This experiment is only surprising to the internet diet crowd, but not the MDs or PhDs that actually work in this area. Yes, longer times on moderate or high carb would be expected to sustain the benefits he saw in the short term.
@ylcalif36816 ай бұрын
Oh, THAT's why most kids don't get heart attacks . . . they eat Oreo Cookies and Twinkies.
@saltdoll52886 ай бұрын
I’d suggest that what you were experiencing “on Oreos” was more akin to PMS, not a period. I assume there was something absent that is a pretty big part of a period.
@naaras6 ай бұрын
So, we can conclude from this study that oreos are safer and more effective way of treating high ldl than statins?
@watchnpray2476 ай бұрын
Kudos to Dr. Norwitz. This is like David vs. GOLIATH.
@moistdepression7 ай бұрын
OK is this surprising at all? Like is it just me or is there a massive lack of scientific literacy and overblown sensationalism running around the comments. Like I understand the point of being disruptive and doing things in the literature to make a point, but from the comments alone you can tell this is being misinterpreted pretty heavily, and the case report is intentionally styled to do that. People with high LDL and accompanying CVD comorbidities are going to look at this as an excuse to refuse statins or changes to their diet. Come on now.
@robyn33497 ай бұрын
Thank you!
@BLAZINBEATS1236 ай бұрын
Man, I have been eating Oreos for the last week. Nothing's changed. I think my cholesterol is worse. What the.....
@meatdog7 ай бұрын
Okay, but what did it do to your VLDL, Triglycerides, Lipo a, APO b, CRP, uric acid, Blood sugar and HgbA1c???? And what was your wash-out protocol? Also did you account for the high fat content in the filling as the actual component that produced this effect. I will read the study because there seem to be several confounding variables at work here. And it's pronounced "Hila, not Hard g, gila.
@T-aka-T7 ай бұрын
The washout period was 3 months. BUT - do you want answers, or RU just chucking rocks? I'm sure the info is available if you actually look/ask, rather than appear to be just sniping from the comments section. 😮
@cherylking14595 ай бұрын
I am slightly outside the lmhr numbers at ldl 258 hdl 78 tri 101. But the Dr's keep trying to get me on a level 40 statin and I keep saying no. Been eating less carbs for 40 years and have great health.
@kathya19567 ай бұрын
What is it in Oreos that make it a powerful agent in LMHR to lower LDL. Is it the carbs? I guess so because that’s all that they are. Carbs and fat. Fat is s in a keto diet already. So how many carbs per day? Is it linear? Lea carbs less reduction of LDL?
@metabolicmind7 ай бұрын
Yes, presumably it is the carbs, so his body burns glucose and doesn't need to traffic triglycerides for energy,
@finagill7 ай бұрын
I don't think LMHR is a thing. I think that this is a normal function that applies to all. The lower our triglycerides in our blood and stores means that we will need more VLDL to find any available triglycerides. The problem is that there are so few people that are lean and doing low carb that they seem to be an exception.
@aztonyusa7 ай бұрын
LOL, I had the same thought. I can see Nabisco or some cookie company advertising how healthy eating their Oreo cookies are. See, they lower your LDL cholesterol. You know there are people out there that will believe it. That's why there's a warning label on hair dryers to not use in the shower or bath.
@wmfami7 ай бұрын
Really hope Malaysian Ministry of Health upper echelons watch & understand this.
@T-aka-T7 ай бұрын
So you're an unreconstructed optimist ...😂
@fantasticallyfit60306 ай бұрын
To me a point that comes out of this, is that doctors shouldn’t be pushing LMHR or patients trending this way to use statins without more information. Many doctors threaten patients with noncompliance and discontinuing care if the don’t use statins. I am a DC, CCN and a LMHR. Patients can eat a sweet potato every day and see the same thing
@bortbort16 ай бұрын
So, you went Keto (lowering your carb consumption) and your LDL went up. Then you went off Keto (by consuming 100g more of carbs per day) and your LDL went down. Why is this news?
@cherylking14595 ай бұрын
Let's move that cognitive dissonance to the people taking statins and the doctors prescribing them.
@johnhawkins35076 ай бұрын
Result of the study - People on a keto diet benefit from some carbs. People on a keto diet long term develop high cholesterol. Take statins, or add some carbs and get away from ketosis.
@patriciahoke47226 ай бұрын
Well @john, that's not what he'd say. (As an aside, as much as I'd like the supposed benefits of keto, I don't think I could do it. I think I'd feel gross a lot of the time. It's not a diet as popular with women as it is with men.) He'd say that the high levels of LDL just reflect the TRANSIT of the lipoprotein, not the build up of it.
@andyobrienAOBSS6 ай бұрын
Beyond doing a test on a hyper responder and comparing results from Oreo’s to statins this experiment really isn’t new or surprising. What about Mark Haub’s Twinkie diet in 2010 that caught media attention. Walter Kemper’s rice diet is over 80 years old. His rice diet clinic still exists today.
@azdhan7 ай бұрын
Starting tomorrow, I am going full blown oreo cookie diet. Like you, I am a LMHR, so if it worked for you, there is no reason it shouldn’t work for me. I am very confident in your finding and sure it will work for me too. Thanks for sharing
@Shakerhood696 ай бұрын
You can add a sweet potato instead of cookies and get a similar result.
@GeorgeOu6 ай бұрын
Why conclude Oreos are unhealthy just based on "trust me bro, it's common sense", why not test it? There was a professor in the 2000s that went on an all Twinkies diet plus 1 multi-vitamin a day to lose weight. He not only lost a lot of weight, every health metric like colesterol improved.
@sassy22157 ай бұрын
It does not mean that you should be eating Oreo's but if your life insurance company is using your high LDL to reject you for a policy because of your LDL marker flags you as "high risk" for CVD then you might be justified as an LMHR to eat a bunch of Oreos right before you get your blood work done so as to game the "system" that is using the "system" against you.
@blademan40436 ай бұрын
When I was young I was eating ton of cookies, pies pizzas etc. and my cholesterol was always low, now at older age it's not the case. Simple
@Storiedtold116 ай бұрын
Gonna eat them for breakfast, lunch and dinner. My guess is the chocolate Oreo has more antioxidants than the golden Oreo’s.😅
@JungleJargon7 ай бұрын
My brain is fine. The speed of light C isn’t constant since the measures of time and distance aren’t constant. Changing from 60 kilometers an hour to 60 miles an hour changes your speed. Then if you go from 60 miles an hour to 60 miles a minute it increases your speed again. This what is happening in general relativity when less gravity increases the measure of distance and speeds up the rate of time over large distances. My head works fine.
@ptbwinland1467 ай бұрын
I don’t even know, the doc says Keto is for healing these issues, and not necessarily a replacement for a standard diet, but it seems like their should be be more investigation into keto or low carb being the preferred diet. Just look at the American public walking around for a while, seems apparent their are some issues with the standard of eating
@Jimfrenchde6 ай бұрын
I don't have common sense. What is wrong with refined carbohydrates? I don't think we should just blindly go with the medical orthodoxy. To just say don't eat Oreo cookies because they aren't healthy like other junk foods isn't convincing to me.
@JWB6717 ай бұрын
Big deal… I dropped my LDL from 238 to 65 using the old school Pritikin diet after being low carb, high fat for years… zero drugs.
@jellybeanvinkler48787 ай бұрын
Is that low protein?
@KenJackson_US7 ай бұрын
The whole grains, vegetables and legumes in the Pritikin diet are loaded with oxalates, lectins (including gluten) and phytates, which are anti-nutrients and can cause inflammation. Keto and carnivore are much healthier.
@jamesdellaneve90057 ай бұрын
Your condition is not rare. You’re not LMHR. If you were metabolically healthy, the 238 LDL was likely not risky either. But standard of care doesn’t recognize metabolic health as a factor. Studies done with those with familial hypercholesterolemia showed that the high LDL was in many cases fatal for those with F8 clotting factors. Those without the clotting factors lived normal lives with super high LDL.
@stargazerbird7 ай бұрын
But Nick lowered his while still eating his regular keto diet. Not the same
@johnow77 ай бұрын
There was a Swedish study following over 44K seniors 65-99 years of age over a 35 year period. All of those who made it to 100 years old had high cholesterol. Brag all that you want.
@250txc7 ай бұрын
Big pharma will first try to kill this story behind the scene before it ever gets off the ground ... Or maybe try to make some weird joke out of it and attack Nick in some manner ... lol
@nicknorwitzPhD7 ай бұрын
Bring it on...
@SydneyCollin7 ай бұрын
Can't wait for a Peter Attia smear and Tom Dayspring tantrum!
@250txc7 ай бұрын
@@nicknorwitzPhD Good luck if they do and you guys have certainly thrown a monkey wrench into the clogs of their board meetings.
@250txc7 ай бұрын
@@nicknorwitzPhD Let me explain my words a more closely here ...Sure you know this but big Pharma holds all the cards now and are backed by the US government (FDA) to a degree. These guys have already won the fight over the aspects of nutrition your N of 1 testing is pointed at and proves they are incorrect to some degree about the health of its citizens. -- They have no reason to open channels up to or even against you because the fight is over and they won decades ago .. A ground swell from the bottom up might force the powers-that-be to crack and maybe engage you and Dave... -- As interesting as this LMHR saga is, seeing how the FDA or whoever is chosen to come out to challenge all your data and Dave, will be eye opening also. I certainly believe you guys are up for any thing big Pharma might throw at you...
@scottslomka2406 ай бұрын
If you are severely carb depleted there will be massive response to any carbs
@jameslefleur19706 ай бұрын
Well don't worry about Oreos not being healthy since statins aren't healthy either....
@jk35216 ай бұрын
Wish there were this type of answer to me raising my low HDL !
@MrQuay036 ай бұрын
What are you taking about? Oreo and sugary cereals are super healthy
@MyChilepepper6 ай бұрын
I had two pieces keto Oreo chaffles today. Now I’m uncomfortably hyper bloated. Seriously 😢
@protovu6 ай бұрын
The cholesterol numbers paradox is interesting, but will you be having a coronary calcium scan and a dopler of the corotids and posting the results?
@bilguana117 ай бұрын
Take the bananas out of your smoothie and substitute Oreo cookies.
@truthseeker47406 ай бұрын
Wait, isn’t it a high LDL cholesterol level good for our bodies’ organs functioning?
@emilsimanian22756 ай бұрын
So which part of the oreo lowered ldl, center white soft part or hard brown cover buscuits?😂or it has to be combination? And branded oreo. If it is orion but same material, does it make difference?
@LKChaqi7 ай бұрын
What about Oreo cookies effects on Apo B ?
@Corkfish17 ай бұрын
As you age your cells won't have the same capability to absorb LDL so you'll have excess floating around your blood stream. I'd like to see him repeat this when he's 60.
@lindax9116 ай бұрын
@4:18 *Four times* as effective: Twice the reduction in LDL in half the time.
@stevenhernandez89666 ай бұрын
I tried to think of the least destructive carb, something I loved from my childhood (Sta Puft marshmallow man knocks at door)
@kathya19567 ай бұрын
Cheerios or Oreo cookies may not reduce LDL in non LMHR individuals.
@RalphEllis7 ай бұрын
Is it the biscuit, or the disgusting cream?? More data required. R
@gbowlr85123 ай бұрын
Can I use Chips Ahoy instead to lower my LDL? Thanks
@huguettebourgeois63666 ай бұрын
Harvard? What’s that?
@KatharsisderWelt7 ай бұрын
Doctor's need to get off their ego trips.
@kathya19567 ай бұрын
That’s correct about GLP-1 agonists.
@patriciahoke47226 ай бұрын
What's not being said, which leaves me legitimately curious, is that his cholesterol was lowered BECAUSE he started from a ketogenic perspective. They need to say that this likely will not happen to other people because hardly anyone eats keto all the time!
@anythingyoucando15466 ай бұрын
I wonder if it is the habit of snacking?
@nicholaspostlethwaite95546 ай бұрын
The interesting point of this is if the super high ldl levels are not harming these LMR types, then the concept that high ldl is harmful and is the cause of heart disease is shown up as wrong. So Statin use has no basis. Meaning there now needs to be more science looking at what really is causing the heart disease! It may be high ldl in combination with something else. It is not obviously untrue that eating more than your very low carbs is bad just because you used Oreos. Does not matter if you raised the carbs with Oreos every day or anything else. Training the taste buds. Yes that bad old thing, so called 'acquired taste'. Used to make alcohol palatable and various horrible green veg. Cheating your taste, that developed over evolution to warn of bad foods and tell of good is not smart. Above all else it is ever more clear, no one knows anything at all for certain about anything diet and eating related. It is all opinion and basically made up. Heaps more good science needs doing. Meanwhile eat what you like and enjoy. Living longer eating horrible food is not worth it!
@blahblah67257 ай бұрын
I think triglycerides and LDL are two different things. Please clarify, are they the same or not?
@metabolicmind7 ай бұрын
You are correct that LDL and triglycerides are different. LDL is a type of cholesterol particle whereas triglycerides are lipids or fats.
@porkpie28847 ай бұрын
Why would you want to lower LDL?
@BRunner127 ай бұрын
Because they say so, even though they know it's not casual...
@porkpie28847 ай бұрын
Exactly @@BRunner12
@John-gu4rw7 ай бұрын
So does this mean Oreo cookies will be $30 each now.
@michaeljohnson33837 ай бұрын
So, is he saying that very high LDL cholesterol is not harmful in lean responders on a keto diet?
@nicknorwitzPhD7 ай бұрын
did not say that
@michaeljohnson33837 ай бұрын
@@nicknorwitzPhD Hey, great to hear from you. I know you didn't say that but I'm really curious to know if you think that a keto diet is problematic for you or whether you think it's healthy despite the high LDL. Slight digression, but do you think that the Inuit having evolved to avoid ketosis even when eating what would be a ketogenic diet for most other people, suggests that ketosis is not great for human health long term.
@KenJackson_US7 ай бұрын
I recall a Korean study with a cohort of millions plus another study that show higher LDL correlates with lower all-cause mortality. One might conclude that LDL is protective.
@nicknorwitzPhD7 ай бұрын
@@michaeljohnson3383 For the former, I think it's possible that the LMHR phenotype is lower risk than many might think. But I don't have the data to claim that and, therefore, aim to provoke questions and pursue those data. Re Inuit, no... I wouldn't interpret it like that
@michaeljohnson33837 ай бұрын
@@nicknorwitzPhD Thank you for the reply - very interesting re the LMHR phenotype. I'd also be interested in your APOB levels as a LMHR on a keto diet - if you discuss that on any of your videos. Really appreciate your taking the time to reply.