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Gas chromatography | Chemical processes | MCAT | Khan Academy

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khanacademymedicine

Күн бұрын

Understand how to separate and purify chemicals through gas chromatography and how to interpret a gas chromatogram. By Angela Guerrero. . Created by Angela Guerrero.
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Пікірлер: 183
@hollywoodbb
@hollywoodbb 2 жыл бұрын
I’m a chemist and use multiple GCs every day. In my line of work, we’re more interested in how MUCH of a compound is in a sample rather than trying to identify a compound. But we also do look for the presence of a compound in certain scenarios. GC is excellent for both applications. To all you students, YES you will actually use these everyday if you go down a chemistry route. Familiarize yourselves with them. In my lab, titrations are also pretty prevalent as well as spectrometry and moisture analysis. A lot of it is automated which is a breeze, but we do manually perform some of these techniques. Chemistry is MUCH harder in college than in the field and I know how defeated I felt at times as a student. Hang in there and stay on the path! I enjoy my job now and at 26 I made 6 figures this past year. It’s worth it, I promise!
@pearlz4796
@pearlz4796 2 жыл бұрын
how far did you get into your education?
@hollywoodbb
@hollywoodbb 2 жыл бұрын
@@pearlz4796 I completed a 4 year degree and got my Bachelor of Science in Biological Science.
@NewWesternFront
@NewWesternFront Жыл бұрын
How did you secure employment?
@lorechadominic4920
@lorechadominic4920 Жыл бұрын
Thank you😅
@hollywoodbb
@hollywoodbb Жыл бұрын
@@NewWesternFront I knew the company was hiring and just submitted my resume and the company had 2 people leaving, so they were in need of replacements. And I did really well in the interview. A lot of times it’s just timing, too. Tips: Really polish your resume and spend some time curating it. If you can get past that first step, then you can really shine at the interview! Before you go into the interview, look up facts about the company and familiarize yourself with it. In my interview, the first question was, “So tell us what you know about the company?” And luckily I was able to speak for a minute or so about them, which they seemed to really like. It shows that you’re invested and aren’t just going to say, “idk I just want a job.” Also, knowing someone in the field definitely helps if you have that luxury. If you’re still in school, make sure to network and stay on good terms with your professors. A recommendation can go a long way. Oh and lastly, to my surprise, they hardly touched on chemistry in the interview. Most places just want you to have a basic knowledge/education of the field, then they’ll train you on the job the way they want. I think the only chem related question they asked me was which techniques I was familiar with. I basically just rattled off the analyses I had done in my labs (titrations, GC’s, capillary action, pH, etc.) and they essentially told me the main ones I’d be doing, and they would train me on the specific instruments. They mainly wanted to know how I work with others, if I can provide attention to detail, am I teachable, etc.
@hayley0Lewis
@hayley0Lewis 10 жыл бұрын
Explained a million times better than my lecturer in a fraction of the time...thank you
@basharkhan6779
@basharkhan6779 5 жыл бұрын
thanks
@korykubasek347
@korykubasek347 10 жыл бұрын
khan academy has made my college life so much easier keep it up!
@henriklarsen8193
@henriklarsen8193 8 жыл бұрын
You're doing a marvelous job, even at making chemistry sound adorable (the baby / sumo part)!
@elvinhasanaj9849
@elvinhasanaj9849 2 жыл бұрын
You saved me big time with this video. The explanation was clear and straight to the point summarized 50 textbook pages in 8min. I love u guys.
@NathanielIReiff
@NathanielIReiff Жыл бұрын
10+ years out of high school and I’m still using the Khan Academy!
@sbmuthuraman
@sbmuthuraman 10 жыл бұрын
Gas chromotography was explained in a simple manner and in detail covering most of the aspects of GC.
@syu11079
@syu11079 9 жыл бұрын
great video! before stumbling on this video i spent ages reading textbooks, but still didnt quite get GLC. but your video explained it perfectly, so thank you! :)
@jamesperry4470
@jamesperry4470 10 жыл бұрын
Good video, but I think it would be good to mention adsorption and why it is a fundamental concept in chromatography and the separation of the mobile phase by their polarity. This would help touch more on the uniqueness of the electron distribution (like if you looked at an electrostatic electron density map) and help communicate how unique each molecule really is when looked at through the means of any system of chromatography
@andreac.5596
@andreac.5596 4 жыл бұрын
Thank you! I knew a little bit about GLC, but never really understood the carrier gas, mobile and stationary phase. I appreciate you so much for explaining this in detail!
@simflorianwilliam8617
@simflorianwilliam8617 7 ай бұрын
The only good thing about this channel is, I always like the video before playing it, iam loving gas chromatography now 😊
@mithili3906
@mithili3906 9 жыл бұрын
Your handwriting is fancy
@1987crfe
@1987crfe 2 жыл бұрын
This was sooooo easy to understand. Crisp and Clear! Thanks a ton!
@marlonhowe7592
@marlonhowe7592 11 жыл бұрын
This is awesome (-: I always use English explanation videos for Chemistry, as in German there just aren't any videos which combine theory and "fun" (?) as much as you have with the example of the sumowrestler. Really nice, thank you. (-:
@Marawan
@Marawan 4 жыл бұрын
this explanation just summed an entire part of my syllabus in only 8 minutes! Brilliant!
@Simis999
@Simis999 8 жыл бұрын
Such a friendly way of explaining, thanks a lot :)
@basheeranwar9058
@basheeranwar9058 7 ай бұрын
thank you so mush , I hope that you explain more topics that related to the chemical engineering
@kavitaselvaraj3216
@kavitaselvaraj3216 9 жыл бұрын
So informative and easy to understand. Thanks.
@J_just_J_yes
@J_just_J_yes 10 жыл бұрын
This is a great video, i'm doing a lab report about my gas chromatography and are not sure about what is actually going on for discussion sake's. Now i feel i have a better idea how to explain my data and reason it! Thanks! :) P.S. and the girl's voice is helpful in making sure males(such as myself) are still glued to the video till the end XD
@arunimachakraborty6423
@arunimachakraborty6423 7 жыл бұрын
I can't thank you enough for this. Bless you. :D
@ashishtodakar4307
@ashishtodakar4307 7 жыл бұрын
Arunima Chakraborty I love you
@lovemymonkey05
@lovemymonkey05 9 жыл бұрын
I wish I had found your videos when I was still in college.
@Zetarrino
@Zetarrino 8 жыл бұрын
What about the different polarities of the mobile versus the stationary phase? The substances within the compound that have the opposite polarity of the mobile phase will have traveled slower than the the ones with the same polarity due to attraction/repulsion. Would have liked a little more information about this.
@easylearning981
@easylearning981 8 жыл бұрын
+Zetarrino Hello. Usually, if memory does not fail me, you can NEGLECT intermolecular forces in gas phase for many purposes. So compounds having lower boiling points will just flow within the gaseous inert stream, whilst those with higher boiling points will stay liquid for longer (not necessarily interacting with the liquid stationary phase). What really matters here is that substances with higher boiling points, as long as they stay liquid, will not be able to "flow with the wind", at all. :-) Anyway, I think your question is very worthy. For example, if bigger apolar molecules are mixed with smaller polar molecules. The latter ones were supposed to boil first, but due to interaction with the stationary phase, they do not. Maybe that would invalidate the result somehow.
@andrewk7470
@andrewk7470 8 жыл бұрын
"flow with the ... we will never know.
@joylynjake4268
@joylynjake4268 2 жыл бұрын
I'm prepared for my chem lab thank you 🙏🏼
@maansaab987
@maansaab987 10 жыл бұрын
loved your voice
@prashanthraju4013
@prashanthraju4013 6 жыл бұрын
Nice explanation. You said that sample separation in the column ( stationary phase ) is based on the boiling point & molecular size of the solutes present in the mobile phase. Actually it also depends on the polarity also. For example 1. Polar stationary phase & polar mobile phase has more retention time 2. Polar stationary phase & non ploar mobile phase has no interaction so sample in the mobile phase moves faster, lesser retention time. If it's not correct plz ignore my comment. Thanks for ur superrr explaination.
@charlottebikech
@charlottebikech 9 жыл бұрын
your voice sounds so much like leighton meester's
@yhpk9013
@yhpk9013 8 ай бұрын
Well explain! Thank you so much, I finally can understand the GC.
@demetriosgianitsas9008
@demetriosgianitsas9008 7 жыл бұрын
You literally saved my day, great explanation thank you very much!!!
@bakhodirjonkakhkharov344
@bakhodirjonkakhkharov344 2 жыл бұрын
Sal Khan is Elon Musk in education! Thanks for this amazing platform
@seluffhello873
@seluffhello873 8 жыл бұрын
What if a small compound with high boiling point and a bigger compound with low boiling point is in the mixture? Would that mean that more or less, they would travel at the same rate and will produce only 2 waves in your graph instead of 3?
@prateekgupta3454
@prateekgupta3454 8 жыл бұрын
amazing explanation
@josyzong7919
@josyzong7919 5 жыл бұрын
A good video!!! A lot better than my professor. Clear and easy to follow the logic.
@syamkumar6075
@syamkumar6075 10 жыл бұрын
GasChromatography was explained in a simple manner and in detail covering most of the aspects of GC.
@msiloveme16
@msiloveme16 2 жыл бұрын
Very clear, slow and steady! thanks
@trevorndhlovu7834
@trevorndhlovu7834 4 жыл бұрын
Fantastic staff my lady it's COOLSOME,I owe you one.
@umawww
@umawww 6 жыл бұрын
thank god this channel exist
@awesomemangoes8072
@awesomemangoes8072 5 жыл бұрын
Thank you
@MadanKumarLakshmanan
@MadanKumarLakshmanan 7 жыл бұрын
Excellent video. Very clear & informative. Sincere thanks.
@simplestatic3751
@simplestatic3751 Жыл бұрын
I used the Hewlett Packard 5710a dual-column gas chromatograph with a flame analysation detector.
@anghaitruyen240
@anghaitruyen240 8 жыл бұрын
Would you like to tell me what program you used in your clip?
@anounymous7988
@anounymous7988 2 жыл бұрын
You're amazing god bless you 💖💖💖💖
@hayaalmly6083
@hayaalmly6083 4 жыл бұрын
Thank you! you made it so easier to fathom even for a 7 year old boy!!
@turkishgamernl8047
@turkishgamernl8047 8 жыл бұрын
hi, im a student and i have a question about the boiling temperature. why is it that the one with the higher boiling point is going slower and adsorbs better and the other with the lower boiling point is faster and adsorbs badly? is there a reason for or is it just a rule you have to know about gas chromatography?
@prakharawasthi7062
@prakharawasthi7062 8 жыл бұрын
more boiling point lesser it will be volatile, it will bind to liquid surface of column
@agent475816
@agent475816 8 жыл бұрын
+Turkish GamerNL If it has a high boiling point, that means that it prefers to stay as a liquid compared to a gas that has a lesser boiling point.
@lerlia_af
@lerlia_af 3 ай бұрын
Great video!
@rutabnoor4285
@rutabnoor4285 3 жыл бұрын
Ahh atlasttt i found you ... Very thankful
@mohammadkhojazada104
@mohammadkhojazada104 3 жыл бұрын
I kiss your eyes. Thank you very much :) You explained that so nice👍🏼
@smthgsmthg1717
@smthgsmthg1717 3 жыл бұрын
Thankyou. You explained very well.
@cindycho2933
@cindycho2933 2 жыл бұрын
Very helpful, thanks!
@johngrantner7240
@johngrantner7240 7 жыл бұрын
So good. You kick ass. This made it so much easier to understand
@Lostpanda123
@Lostpanda123 7 жыл бұрын
Great explanation.
@mustakim2144
@mustakim2144 3 жыл бұрын
Thank you!
@digvijayyamagekar7139
@digvijayyamagekar7139 5 жыл бұрын
Thank you so much !!! I got the idea now .
@guyweizman3791
@guyweizman3791 3 жыл бұрын
Perfect explanation!!!
@aboodqashoo4113
@aboodqashoo4113 3 ай бұрын
And, The affinity is an important factor of separation
@MrBlash93
@MrBlash93 9 жыл бұрын
Great explanation. Thank you for your video
@jenishbarot7171
@jenishbarot7171 6 жыл бұрын
thank youuuu......perfect explaination.
@kingoffunny1747
@kingoffunny1747 9 жыл бұрын
Why does it sound like more than one person is speaking?
@DreadnaughtyArt
@DreadnaughtyArt 9 жыл бұрын
King Of Funny The microphone volume keeps changing.
@michaelbowe1485
@michaelbowe1485 9 жыл бұрын
King Of Funny Multiple personality disorder
@MightyOwl_01
@MightyOwl_01 8 жыл бұрын
+King Of Funny In my classroom ppl are watching without headphones and all i can hear is blah blah blah lol, i cba to get my headphones so i just used subtitles
@Syeal7
@Syeal7 6 жыл бұрын
I think parts of the recording was edited over with additional comments or corrections in which the original "tape" lacked. So the different volumes are actually recorded during different times.
@btslovers9788
@btslovers9788 3 жыл бұрын
I love your videos. So elaborate!
@stephanieme4405
@stephanieme4405 4 жыл бұрын
If my doctor asked for it could he test for my prescription drugs Cymbalta and Lamictal Respridone or and others to make sure I was taking them or to see how much of them was in my system to affect other drugs I was taking?
@mayanksangam9205
@mayanksangam9205 3 жыл бұрын
Thank you ma'am
@Lagos08
@Lagos08 8 жыл бұрын
Thank you very much for the explanation
@sudeepm6484
@sudeepm6484 3 жыл бұрын
what if the difference in the boiling points is not much and the sizes of the molecules of both compounds are also nearly equal? Do the peaks overlap? How to distinguish in such cases?
@obinnaduke
@obinnaduke 6 жыл бұрын
You're awesome... Thank you so very much
@fitnesswe
@fitnesswe Жыл бұрын
phenomenal
@Muik69
@Muik69 8 жыл бұрын
Simple and great explanation thanks!
@dan.6398
@dan.6398 9 жыл бұрын
Absolutely great way of expanations. I coudn`t find anything better. Thanks ;)
@mohamedmamdouh4782
@mohamedmamdouh4782 4 жыл бұрын
I have one question regarding the temperature of inlet that is around 200 degree then sample is vapourized. After that it is introduced to column via carrier gas. Temperature in oven is ramping starting from might 30 till 220. The question is from high temperature of the inlet to slightly low oven temperature might lead a kind of condensation, how the sample still in vapour state during it 's journey to column. Plz illustrate.
@SPYSpreads
@SPYSpreads 8 жыл бұрын
Remember that the ones that travel the fastest or farthest is the one with low B.P and vice-versa!
@lifeofastudent...317
@lifeofastudent...317 Жыл бұрын
What if it as similar boiling point and size? How can we distinguish it?
@azagoodwin5899
@azagoodwin5899 9 жыл бұрын
great simplified video ./.... i need more information for which type of substances can we use this technique for? e.g drugs and also what does the height of the peak tells us
@easylearning981
@easylearning981 8 жыл бұрын
+Aza Goodwin The height of the peak informs the intensity. The more molecules reach the detector, higher the peak.
@razo786
@razo786 10 жыл бұрын
Thanks.
@Alicia-dm6yb
@Alicia-dm6yb 8 жыл бұрын
awesome video..very well explained...
@videogrillo
@videogrillo 4 жыл бұрын
Shout out to one of the best explanations. Congrats Angela, smooth and clear. Indirectly I learned that GC is very destructive and I won't have a sample afterwards
@unknownknown7427
@unknownknown7427 2 жыл бұрын
Superb 👍
@eiliannoyes5212
@eiliannoyes5212 3 жыл бұрын
That's how you do it!
@kayleighprice9637
@kayleighprice9637 6 жыл бұрын
Thanks again!
@dannytitus1645
@dannytitus1645 5 жыл бұрын
this was really great. Thank you :)
@jitendralodha13
@jitendralodha13 10 жыл бұрын
thanks a lot.
@IIAmzazZ
@IIAmzazZ 10 жыл бұрын
really helpful thanks
@DuongNguyen-ni9gz
@DuongNguyen-ni9gz Жыл бұрын
excellent
@xClaireW
@xClaireW 10 жыл бұрын
great explanation!
@aliimadyounis2056
@aliimadyounis2056 5 жыл бұрын
Thank you ❤️
@kennytzz4073
@kennytzz4073 7 жыл бұрын
Thank you!!!! u saved me !!!
@samulasaidireddy
@samulasaidireddy 9 жыл бұрын
kindly explain of oven track in Gas chromatography
@akram4139
@akram4139 5 жыл бұрын
Thanks so much
@lucyaudrey733
@lucyaudrey733 9 жыл бұрын
very nice thank you
@daindelucia7033
@daindelucia7033 6 жыл бұрын
It looks like that, in your graph, time increases toward the origin.
@boringgrass
@boringgrass 8 жыл бұрын
wow nicely explained
@bushrayousef8766
@bushrayousef8766 8 жыл бұрын
awesome video! thank you :) x
@365messiah
@365messiah 7 жыл бұрын
Great informational
@mustafabasim684
@mustafabasim684 7 жыл бұрын
Great job
@Everyonecallsmesophie
@Everyonecallsmesophie 2 жыл бұрын
I love you so much. I really do
@dynamicguy2393
@dynamicguy2393 8 жыл бұрын
this is all theory. please, can show as some real time videos on this, any way, I appreciate your effort
@minjinoh4998
@minjinoh4998 10 жыл бұрын
Big help
@omymamohamed29
@omymamohamed29 4 жыл бұрын
Excellent 💜👏
@josephchong783
@josephchong783 6 жыл бұрын
Your voice is amazing
@chem-issatwait9528
@chem-issatwait9528 2 жыл бұрын
Sumo wrestler yeah understood thanks!
@80amnesia
@80amnesia 9 жыл бұрын
neat, thumbs up
@prashantprajapati5709
@prashantprajapati5709 6 жыл бұрын
I have a doubt regarding the separation of the compound, suppose you have 2 compound one is lighter and have high affinity towards the stationary phase and the other compound which is heavier and have low affinity towards the stationary phase and the sample which contains both the compound is run in the gas chromatography then which compound will move out first?
@Shahram19702010
@Shahram19702010 2 жыл бұрын
That’s why methods development is very crucial. Temperature ramp will resolve your problem.
@aishwaryas2263
@aishwaryas2263 7 жыл бұрын
bless you
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