Science says THIS is the ultimate hangover cure
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3 жыл бұрынWatch this video without ads here: nebula.tv/videos/sophs-notes-...
Alright, not drinking at all is the perfect hangover cure. BUT let's find out if any of the other classics have any scientific evidence behind them. Feat. devilled eggs, a year of wildness, and an unwelcome box.
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References
The questionable role of dehydration and electrolyte imbalances
pubmed.ncbi.nlm.nih.gov/20712...
pubmed.ncbi.nlm.nih.gov/1253812/
www.alcoholhangover.com/hangov...
Good news article that covers: Dehydration potentially not being that important, role of inflammatory response, mention of some plants, Prof David Nutt.
www.wired.com/2014/05/hangove...
Alcohol’s breakdown into acetaldehyde
pubs.niaaa.nih.gov/publicatio...
Why hangovers feel worse with age
www.sciencealert.com/here-s-w...
(This one also mentions the origins of the word ‘Veisalgia’)
www.nbcnews.com/health/body-o...
Cysteine and Acetaldehyde
onlinelibrary.wiley.com/doi/f...
The ‘plant concoction’ experiment
News article: www.independent.co.uk/news/sc...
Actual paper: nutrition.bmj.com/content/3/1/31
Immune system importance
pubmed.ncbi.nlm.nih.gov/20712...
www.wired.com/2014/05/hangove...
Cognitive effects of hangovers
pubmed.ncbi.nlm.nih.gov/18238...
More general articles on hangover cure myths
www.sciencealert.com/the-most...
www.sciencealert.com/scientis...
theconversation.com/mondays-m...
David Nutt photo
www.imperial.ac.uk/people/d.nutt
@SophsNotes 3 жыл бұрын
A mate of mine swears that the ultimate hangover cure is a pack of BBQ Hula Hoops and a bottle of Lucozade (not #spon I promise). What are yours?
@sheaedwards1999 3 жыл бұрын
An odd one but the gym (only for a mild hangover though, i think if i was properly hungover my body would give up) a fry is my usual go to
@SophsNotes 3 жыл бұрын
A solid pair here. I feel like exercise works as a distraction more than anything, so I stop feeling so sorry for myself 😅
@THE-X-Force 3 жыл бұрын
It's important to note (9:15) that ibuprofen (or any medication containing a NSAID) raises the risk of severe stomach bleeding for people who drink 3+ alcoholic drinks per day during the same time that they take the ibuprofen. Just anecdotal, but I find the best way to "cure" a hangover, is too avoid getting one. I stick to clear liquors like vodka, on ice, with usually nothing else.. but you can add lime, seltzer, whatever, but what you're trying to avoid is anything sugary. That goes for all drinks. The sweet liqueurs and mixed drinks with coke etc (Jack & Coke for example: dark booze plus a high sugar mixer) are the recipe for a very bad morning. Along the same lines, for every 2 or 3 drinks you're having, try to get a fresh glass of water in you too .. or some Perrier, Pellegrino, etc. Much better to try to mitigate getting dehydrated, than to suffer and try and rehydrate the next day.
@mothertrucker1262 3 жыл бұрын
Why haven't you uploaded any video this year? Is everything okay
@SophsNotes 3 жыл бұрын
@@mothertrucker1262 All fine! I just took January off to do some planning/organise stuff to do with my day job :) New videos coming in Feb
@jimsbooksreadingandstuff 3 жыл бұрын
I came here from John Green's video, liked what I've seen and subscribed....
@seanrshivers 3 жыл бұрын
saaame :P
@braininajar8474 3 жыл бұрын
yup
@Aris-gf9rq 3 жыл бұрын
me too!
@maggieo 3 жыл бұрын
As have I!!
@Corporis 3 жыл бұрын
Veisalgia is such a wonderful science word. Equal parts inspiring, terrifying, and Norweigan
@corngreaterthanwheat 3 жыл бұрын
I'm a nursing student. I can't wait to drop that word on a patient note to piss off a rude resident lol
@cwharton 3 жыл бұрын
vlogbrothers brought me here! Great video
@cameronh3756 3 жыл бұрын
Hey me too!
@C.Y.123 3 жыл бұрын
Same, I subbed
@cwharton 3 жыл бұрын
@@C.Y.123 yep, me to. This channel is a gem.
@Aris-gf9rq 3 жыл бұрын
me too!
@anna-ne9zk 3 жыл бұрын
so glad john told me about you on vlogbrothers!!! already watched a few of your videos and you're definitely one of my new fav youtubers!! :)
@brandonhenning9540 3 жыл бұрын
"older and wiser and the pubs are shut" hahaha I laughed out loud.. Anyway, very informative thank you!
@vgreen1156 3 жыл бұрын
😂😂😂
@stormd 3 жыл бұрын
The best hangover cure I've found is a hot bowl of Pho. Tons of liquid, salts, just the right amount of grease, presumably casein in the fat brisket I usually get as a meat option, and starchy carbs for a quick energy boost, I've never not felt better after downing that combo after a night of drinking.
@juststeve5542 3 жыл бұрын
1:45 - Don't break the seal! All I've learnt over the years is I can drink good vodka with my Polish friends and bounce back the next morning with little problem, but a few beers with my English mates mean the next day is a write off!
@bloodgain 3 жыл бұрын
Probably because the beer contains more methanol. That's a possible cause that she left out here that I've heard many times. We have a harder time breaking down methanol, and so it makes us feel like crap.
@georgeprout42 3 жыл бұрын
"Alcohol" (ethanol) alone can't cause the hangover. I'll happily drink a gallon of 5% Doodle stout (or other real ales) in a session and be absolutely fine. A single 330m bottle of Becks lager though and I'm dead with a thumping headache the following day. Could be the methanol idea, or something similar to allergies. Certainly we all have different reactions to different drinks. No wonder there's no definitive cure.
@luisdanielmoreno5717 3 жыл бұрын
Just discovered your amazing channel, keep up the good work 👌
@imapiraaate 3 жыл бұрын
David Nutt’s research is so fascinating! Glad you mentioned it in the video :)
@JohnRochford 3 жыл бұрын
The brilliance in timing for this video isn’t lost on me as I lay in bed on Boxing Day morning contemplating what to eat
@karasirarichard3358 3 жыл бұрын
From the vlog brothers... Love🔥🔥🔥
@SophsNotes 3 жыл бұрын
Welcome, and thanks for coming over!
@alaindeturing62 3 жыл бұрын
Happy holidays soph
@SophsNotes 3 жыл бұрын
And to you too! ☺️
@caryrodda 3 жыл бұрын
I seldom drink any more but I still enjoyed watching this. You make science very entertaining and easy to absorb.
@joshuashain5891 3 жыл бұрын
I came here from vlogbrothers, but OMG is that 12tone in your list of Patreons?
@acidstrummer 2 жыл бұрын
Thank you for not letting Tom Scott win that numbers card game in the pub
@ArashiKorosu 3 жыл бұрын
@vlogbrothers thank you for the recommendation, one more channel to watch regularly
@ErickandDerrick 3 жыл бұрын
Great video! I'm with you, I thought hangovers were caused by dehydration. Thanks for the information, can't wait to watch more of your videos.
@SophsNotes 3 жыл бұрын
I'm glad it wasn't just me! Thanks for watching ☺️
@Jesse__H 3 жыл бұрын
I'm thinking tho ... the statement "hangovers are not caused by dehydration" is not the same as the statement "drinking lots of water before my drunk ass goes to bed will not help." Because that's what I do, and when I skip it I always feel worse 🤷♂️. Also it's not something I do _while_ drinking, so I don't think it's decreasing my overall booze intake as mentioned in the video...
@roserands 3 жыл бұрын
Well done Soph 😘
@gravelrhoads 3 жыл бұрын
I usually watch you on Nebula, but I had to come over to KZfaq to make this comment: You are a wonderful fount of knowledge and your accent, tone of voice, and turn of phrase makes it even easier to absorb that knowledge. And yes, I have asked Nebula if they were working on a comment system and they told me, basically that it was still early days.
@SophsNotes 2 жыл бұрын
I've just seen this, thank you so much!! What a lovely comment, I really appreciate it :)
@nickebert1265 3 жыл бұрын
After watching this video, I’m wondering why another popular (although obviously short-lived) hangover cure is to *continue drinking*. Any thoughts?
@Patrickpisawesome 3 жыл бұрын
Disclaimer this is an educated guess. Hangover is almost certainly more than just one cause. Continuing to drink gives your body some water which in the morning we need anyways. Alcohol is a drug so we do experience withdrawal symptoms so continuing to drink can mitigate that effect. Alcohol has a numbing effect so that probably doesn’t hurt either.
@corngreaterthanwheat 3 жыл бұрын
For the longest time, the treatment for mental illness was getting hammered. If you felt hungover from dealing with your depression, you could just start dosing again. Helps deal with the anxiety of sobering up too (Soph has another great video on that!)
@clayz1 2 жыл бұрын
That’s not really a cure. It’s just putting it off. On the other hand, if you are going to drink again, everything you do is just putting it off.
@rosemarychadi7734 3 жыл бұрын
Here from vlogbrother's video. subscribed!
@johnnash2815 3 жыл бұрын
A roll and bacon is hard to stomach when you are hungover? I think I found the problem here, you are not drunk, you are high!
@daniellim8964 Ай бұрын
Oily food is not so good for the gastrointestinal tract after getting seriously drunk.
@jerseylionesses 3 ай бұрын
I was hung over really bad i made soup broth just chicken bouillon salt pepper and Italian seasoning.. I boiled it and drank slowly it was great
@cheminlee37 3 жыл бұрын
I live for that “probably” call out 😂
@quefixxer2455 2 жыл бұрын
Great content ... subd !!
@thebuzzah 3 жыл бұрын
FYI drinking while watching. When I was younger, I actually had brutal hangovers. It's probably moderation by wisdom that they are not so bad lately. I have to say that I have imbibed more in 2020 (thanks, pandemic!) than normal. I haven't had one of those extreme hangovers in quite a while though. Also, I found this channel through John Green/Vlogbrothers. I'm always up for new stuff. I like it so far. Cheers.
@Max-ph5in 3 жыл бұрын
N-acetyl cysteine is great. Also a sneaky weapon in drinking games ;)
@corngreaterthanwheat 3 жыл бұрын
Do you supplement your way to victory in beer pong? *Slow claps*
@yourtypicalwokestoner8117 3 жыл бұрын
@@corngreaterthanwheat So messed up for the opponent though 😂😂😂😂😂😭
@corngreaterthanwheat 3 жыл бұрын
@@yourtypicalwokestoner8117 if you ain't cheatin' you ain't competin'! 🤣
@yourtypicalwokestoner8117 3 жыл бұрын
@@corngreaterthanwheat LMFAO
@CraftDayFriends 3 жыл бұрын
awesome!!
@AmosOfSynhome 3 жыл бұрын
Dealcoholized drinks are an excellent hangover preventative! LOL
@unicornep1818 3 жыл бұрын
Vimto and Fry's Turkish Delight, the best hangover cure in the world. Have a happy mid-winter festival of your choice, and a merry new year.
@mLyonJE 2 жыл бұрын
I've long thought it wasn't really dehydration[*] and periodically consume interesting material on the many ideas, theories, and so forth -- like you say, all still a work in progress on many fronts. ONE thing though is how much it seems to help downing a pint or two of tap-water before going to bed after a night out. My hunch about this is that you're literally handing the body the very "vehicle" it utilises for doing so much of its regular work; and so, whatever it does to "process" toxins etc., it can do quicker and more easily with a quick top-up of the materials (water) it needs to operate. It's not actually dehydrated, it just makes everything going more easily and more quickly to have a surplus slosh into the system at that point. [*] Don't even get me started about everyone thinking we need 2.5 litres of water a day because everyone forgot it was the bottled water companies who told us that in recent decades!! I looked up the scientific paper from which the water companies seem to have drawn this information -- yes, 2.5 litres, followed immediately by a comment that 70% of said water arrives in the food we eat during the day... Yup, more like 0.75 litres of actual water during the day and if you have a glass of orange juice with breakfast, a cuppa or two here and there, a glass of water with tea, you're totally good to go. Not a single overpriced bottle of water in environmentally damaging packaging to be seen! #petpeeve Great video btw :)
@bloodgain 3 жыл бұрын
One possible cause I've heard many times that you didn't cover is ethanol vs methanol. We break down ethanol first and have a harder time breaking down methanol, so we feel bad if we get a lot of methanol. So, at least in theory, the more methanol in the drinks (e.g. beer and wine instead of, say, vodka), the more we're likely to feel bad.
@elijambu 3 жыл бұрын
i was going to say this exact thing. I was surprised it wasn't even mentioned? maybe it was deemed irrelevant or unsubstantiated? Any comment Soph?
@deathscythe767 3 жыл бұрын
Drinking lots of water immediately after ditching the party people and possibly throwing up some of the alcohol if I had gone too far to wake up without a hangover usually does the trick for me. It's not a pretty answer but works. Also, barfing on command only happens when I get really smashed. Any other time that super power goes away lol
@MrSagru 3 жыл бұрын
A few liters of water before and after sleep + a handfull of ibuprofen and I am always up and running by noon
@cameroncook3863 5 ай бұрын
Good job on the research girl 👍 All Makes sense to me
@daniellim8964 Ай бұрын
Oily food is not so good for the gastrointestinal tract after getting seriously drunk.
@cameroncook3863 Ай бұрын
@@daniellim8964 Hey you should do a review for Cheers. After drinking.
@JamieTheMime 3 жыл бұрын
aren't you not supposed to take things like ibuprofen when you've had alcohol?
@guffaw1711 3 жыл бұрын
I take Ibuprofen after too much drinking, so far it has always helped very well with the headaches, drowsiness and most of the nausea. However I still get slight feelings of imbalance but it's managable. I've read that its ability to mitigate the effects of a hangover was already known to its inventor Stewart Adams. Alcohol also degrades the quality of sleep quite drastically, so parts of its symptons should come from severe sleep deprevation. If you are a regular coffee drinker the coffeine withdrawal symptons will also be worse during a hangover, so don't forget to take your Ibuprofen with your morning coffee.
@bsidethebox 3 жыл бұрын
As a person who has battled chronic insomnia, I'd definitely agree that a lot of "hangover symptoms" align with the gross feelings following a bout of insomnia. I can't compare for sure as I hate alcohol and have only managed to down enough to get tipsy once in my life (where I found out intoxication just makes me want to sleep on the table so screw that) Stay up much later than usual (ain't no party like a can't sleep party) and sleep poorly whilst teetotaling and you'll still likely enjoy a queasy tummy, puffy face, slow brain, slowed reflexes, headache, dry mouth, etc.
@Matowix Жыл бұрын
Also if u have a fatal drunk car accident u can avoid the hangover
@British_Rogue 3 жыл бұрын
Dry mouth would be caused by the alcohol itself. Limits saliva production.
@TravisGilbert 3 жыл бұрын
What does broken the seal mean in this context?
@SophsNotes 3 жыл бұрын
When you go for your first wee after drinking alcohol! After that it’s so much harder to hold anything in 😅
@reddragon3132 3 жыл бұрын
What causes the whole "breaking the seal" effect? Is there actually a biological cause for it or is it purely psychological?
@corngreaterthanwheat 3 жыл бұрын
Hangover Devil Sophie is 💯. Please make her a recurring character if possible. Also, when I drank, I'd also chain smoke. Since those are similar chemicals, was I making my hangover worse? (I eventually stopped drinking after chucking in an Uber and losing a day to self induced sickness)
@SophsNotes 3 жыл бұрын
Oh yeah I reckon that was like double layering your hangover Ryan hahah 😅 and I’m not going to tell the story that meant I cut down on drinking 😬
@corngreaterthanwheat 3 жыл бұрын
@@SophsNotes I left out the part where I walk 8miles up a mountain shirtless at 3am... You were a college student in London. I can make some assumptions lol.
@JohnTaylor-xg4jn 3 жыл бұрын
vlogbrothers sent me here. You have been chosen.
@matthewdragomir2261 Жыл бұрын
Typing in "kveis" in google translate doesn't net any results yet go to wiki and it gives the exact same info as you presented here. I guess if the internet says it, it must be true? 🤨
@Ajwontpay 3 жыл бұрын
Did you encounter any research on hair-of-the-dog cures? They seem to be reasonably popular hangover cures (re: this comment section) but my first instinct is that it doesn't seem to make a lot of sense since it'd compound the issues already at play (whether dehydration or acetaldehyde or inflammation)
@SophsNotes 3 жыл бұрын
Yeah I had a short bit on it but cut it out ! Basically saying that the only reason they work is that they’re putting off the eventual hangover aka recovery of your body. So ultimately it makes things worse!
@deadlymouse4364 4 ай бұрын
Facts and fun, fun fact.
@levishaun8334 3 жыл бұрын
Huh, this is interesting. Where I'm from, I don't think I have ever met a person who thought that hangover is caused by dehydration. I have extensive history of drinking with tons of different folks (kind of happens naturally when you only drink at a bar, but very often) so hangover as a topic have been brought up quite a lot. Literally everyone I ever talked to about it has said something along the lines of it having something to do with alcohol decay doing something or other in the brain. I haven't been drinking with your average alcoholic, but not all of them had degrees either.
@rfldss89 3 жыл бұрын
Professor nutt's work seems like some 'brave new world' shit and I'm not sure how I feel about it 😳
@adamogilvie6951 Жыл бұрын
Eggs. Trust me. Lol!
@steffennylenna8889 3 жыл бұрын
kveis or bakrus are norwegian words for hangover....greeting from the arctic circle
@petronellataube2986 3 жыл бұрын
Bakrus! Kul. Är det "rus" och bakrus sagen efter?
@steffennylenna8889 3 жыл бұрын
@@petronellataube2986 rus means something like (alcohol/drug) rush/high....and bak just means after
@TheDarthReagan 3 жыл бұрын
A buddy of mine's mom makes a snack mix that my friend group has begun calling the "Hangover Mix". Just eat a bunch of it before bed, and you'll be just fine!
@SophsNotes 3 жыл бұрын
Scale up the manufacturing and you'll make a killing!
@ekaterinashum3024 3 жыл бұрын
Ok and what is it????
@eliannam.5700 3 жыл бұрын
helloooooo! here from vlogbrothers
@rptbr 3 жыл бұрын
My cure (least what my body craves) is a big spoon of peanut butter, a pint of cold milk and something with sugar: et voila! Speaking of, interesting that sugar wasn't mentioned in this. I always thought as you're intaking a massive amount of "sugars" while drinking, then immediately stopping - felt it could be an overactive pancreas in the routine of processing this sugar, that by morning ends up mimicks a diabetic "low" (lethargic, depressive thoughts, feeling ill) - be interesting to see the glycemic index of the night before / morning after. #theoryforthemixer
@SophsNotes 3 жыл бұрын
Ah yes the sugar theory is another one I came across! I was squeezed on time so didn’t put it in but it definitely seems to have a part to play, and it’s interesting to look at how the components of different alcoholic drinks impact hangovers (with sugar being a big un). I’ll have to try that cure! Sounds like a good one.
@NotKyleChicago 2 жыл бұрын
7:32 - Was that "lowkey" or "Loki" in regards to the idiocy? 😉
@sparkdaniel 3 жыл бұрын
Keep drinking, no hangover. Nice cold beer is a great cure
@bigman5125 3 жыл бұрын
I have found exercise definely works, though really not something you want to do when hungover.
@tajusn4044 3 жыл бұрын
Lass sounds like Captain Kidd from assassin's creed black flag
@TroopsofDoom666 2 жыл бұрын
Im watching this video during hangover now....dafuq!! help me help me!!!
@MrMessiah2013 2 жыл бұрын
One chemical I can attest to from personal experience that has "alcohol mimicking effects" is Phenibut HCL. As far as hangover cures, I have also heard that Turmeric is good. Apparently there is a drink in Japan that is drunk prior to going on a bender that is essentially just a Turmeric shake and is very good for that from what I've heard.
@psa110 3 жыл бұрын
Fryop? Fry up? Yes, was able to figure it out but... Jacob's Join? A full English? You've got to remember a lot of your fans are not British (I'm a Yank). BTW, maybe you could do a video on Desert Mouth. 😝
@DamnedM 3 жыл бұрын
My body is a temple... ...to Grease
@protocol6 3 жыл бұрын
Nothing about hair of the dog?
@SophsNotes 3 жыл бұрын
I actually had a bit in but cut it out to keep the video sleeker. It was just the typical ‘you’re not letting your body recover and it’s a bad idea!’ response 🐕
@aisekaisebc 3 жыл бұрын
Works. Just not the most feasible method.
@seanrshivers 3 жыл бұрын
Lol, my grandfather is the guy who discovered Acetaldehyde... Dr. Richard Dietrich.
@seanrshivers 3 жыл бұрын
They may have allegedly used alcohol dehydrogenase (the enzyme which breaks down Acetaldehyde) in order to eliminate their hangovers :P in unapproved experiments ...
@SophsNotes 3 жыл бұрын
No way! That’s so cool. Hahah I was thinking as I made this I need to get hold of some alcohol dehydrogenase ...
@seanrshivers 3 жыл бұрын
@@SophsNotes If he was still alive i'd ask him how effective it was. :P
@stevebell9339 Жыл бұрын
Activated charcoal or more booze
@karansaulakh8979 2 жыл бұрын
Just don't drink
@FeintMotion 3 жыл бұрын
MANGU
@ItzAzarah 3 жыл бұрын
Waste of time don’t bother wasting time !
@matthiassteegmans8469 3 жыл бұрын
your references are a bit outdated (1976; 2008; 2010). but i do think the subject is interesting indeed!
@SophsNotes 3 жыл бұрын
Yep I agree! We need some fresh research on the topic
@GeoffCanyon 3 жыл бұрын
The book Life Extension, by Durk Pearson and Sandy Shaw, recommended B1, C, and cysteine for hangovers 40 years ago. Unscientific, but it worked for my friends back then.
@love1orhate1boxingnewsupda61 2 жыл бұрын
Speaking from experience Water is the best one you feel yourself getting back to normal slowly but surely And no not no damn water bottle You need a jug or maybe 2 no 🧢 Great video btw
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