The current climate in the fitness and health industry had me believing that sugar/fructose/carbs were the reason I was overweight. So I cut out almost all starchy and sugary carbs, and ate only meat and veggies. I was literally a carbophobe/fructophobe. I did lose weight, but then I came across Layne and watched a series of his videos. Reluctantly, I reintroduced fruits/starches and actually COUNTED CALORIES as accurately as I could, and I began to lose weight even faster. Thank you so much Layne for calling out all of the BS in the industry.

Biolayne, you are growing on me man....at this rate I should start liking you within the next 8-10 years.

I love how he is able to cite and reference all the data he is using to point out the logical fallacies. Great content as always and really had to laugh for the video edit!

Sedentary people are always going to be looking for a way to say their genetic makeup means they don’t believe in calories

Another great vid🙌🙌 thank you Layne💪

Holy crap! That is one of the greatest KZfaq videos ever. I thought you were James Linker for a second there. Great work.

Great video and explanation of how illogical the article comes off! Great explanation of fat loss vs. fat oxidation and the hormones interaction

Love you man!! Great content as always

Love that Bayesian logic at the end, Doc. If X were true, what could we expect to see? Great job as always.

Great breakdown. Thank you Layne!

Always the truth and on point!

I love Layne's videos, stick it to them!!

Get em Layne The ending cracked me up!

Love this!! 👊👊

Amazing video. That ending is one for the ages!

Whatever possessed you, Mr. Biolayne, to create your site's introduction a most erudite and tight synopsis for each topic?!! It's one of the funniest and fitting introductions ever.... Keep Rocking, Biolayne!

This is my newest form of entertainment and education around my favorite topic😂

This video, especially the ending, was great, lol ! Greetings from the Netherlands

Nice vid man 👍

Loved the ending

Lol, I love how layne says "liraglutide." GLP-1 agonists are bomb. Either way, great video!

Layne, you couldn’t have ended the video any better 😂😂😂

Biolayne for President!

Fantastic video

Love “calories is a con” when there’s almost no way to monetize CICO, and pretty much everyone attacking it is schilling some bullshit or another

Hi, great vid, as usual. Just a quick note: Liraglutide is an analogue for one of the incretins we know about: GLP-1. The other is GIP. It's pretty clear from the data that although the "incretin effect" accounts for >2/3 of the Insulin response to food ingested orally (as opposed to parenterally), its the balance of GIP:GLP-1 that really affects your metabolic health, driven primarily by Insulin. GIP is mainly stimulated by food that is easily digested and absorbed in the proximal small bowel (K cells) , while GLP-1 is stimulated mainly by less easily digested food, which is absorbed more in the distal bowels (L cells). A high GIP:GLP-1 ratio is more likely to produce higher amounts of Insulin and drive Insulin resistance, which after decades cas result in Diabetes Mellitus Type 2. Lower GIP:GLP-1 (i.e. higher amounts of GLP-1) ratio actually promotes a more physiological Insulin response, and is not conducive towards developing hyperinsulinaemia/insulin resistance. In fact, in the Roux-en-Y type of gastric bypass surgery, much of the K cells which would otherwise produce GIP are bypassed, exposing the the L cells in the distal bowel to food more than they normally would, shifting the GIP:GLP-1 balance more towards GLP-1. We see this within 72 hours post gastric bypass surgery, considerably before patients lose weight, and this is the primary mechanism by which insulin resistance is reversed. So liraglutide, the GLP-1 agonist, actually acts as a pharmacological equivalent of Roux-en-Y, as do alphaglucosidase inhibitors and as will SGLT1 antagonists when they are eventually released, and shift the incretin balance more towards GLP-1, and thus helps to combat against, and over time potentially reverse Insulin resistance.

Thanks for calling out the BS!

I can now argue when i get reprimanded for shaking my leg while seated lol

Hi Layne, Awesome video! Well done for debunking the bullshit from the Economist! Definitely enjoyed listening to what you said. Thank you for making the video. cheers, Billy

I FUCKING LOVE YOU LAYNEEEE

this is the way. master !!!

I tried everything. Lo and behold calorie counting worked a treat.

Good content, can you provide us with the links to studies ?

Hey Layne, I got interested in the sugar study (got institutional access). Where could I take a look at it? As a side note, how long was it ran? I'm wondering how insulin has an effect on muscle growth/fats when used in bodybuilding but long-term high insulin increases seemed to not do it. Is it just because insulin levels in are supraphysiological when it is used for bodybuilding? Thanks for the great content!

I was starting to zone out until 11:09. Need coffee.

So....how do I get my hands on some of those meds layne.... 😜 def want to add to my supplement routine

Get em layne

Still the man.

Wow that got spicy at the end!

your the man

I want you to interview Dr. Jason Fung

I get what you’re saying about fat loss being a product of a calorie deficit. Do you have any thoughts on constant carb consumption and insulin production and if it causes problems and also the benefits that are touted regarding the use of fat/ketones as a fuel.

Very good critique...thank you for your insight! Is there any evidence that individuals who are insulin resistant (e.g. Type 2 diabetics) do accumulate fat, or aren't able to lose as much fat, as in the standard model you describe? That is to say, does the carbohydrate-insulin model apply differently, when insulin levels are high, for subjects who are insulin resistant?

You are too awesome. So refreshing to see someone who truly knows what they are talking about spilling the beans on all the bullshit

I love this just for the fucking email intro.

Hi Layne, what is your opinion about drinking after a meal. will it interfere with digestion?

Dr. Greg should see this

PRICELESS

That parting note was obscene lol

So what I'm hearing is I need to get that insulin drug, sit back and let this whole thing blow over! Blast that fat away with high insulin levels 🤔😂 keep up the good work Layne + team

Dr. Norton (PhD) i respect your knowledge and I know you know your shit when it comes to nutrition. CICO is ABSOLUTELY THE UNDISPUTED FORMULA FOR WEIGHT MANAGEMENT...But HOT DAMN, my man, did you have to lean in so hard on the haters???? I am a 41yr old UNAPOLOGETIC OMNIVORE, and I 100% believe in the flexible dieting principles. I'm still a bit torn on IF but like you said, it isn't magic.....I just have one question, how much does hormones come into play in muscle hypertrophy in comparison to ones diet??? Like what is the correlation if any??? I know it's been a while since I commented on your vids, but I still love your content Doc. NO DOUBT!!!

Here i am, watching this video eating a piece of brownie with dulce de leche to meet my carb macrosfor the day... I recently lost 20lbs working with Teambiolayne. Now working on reverse dieting. I just thought the irony of this scene was funny...

Layne, I've spent 4 years researching health and nutrition in a completely non bias view. With nutrition, I've concluded it all boils down to 3 simple rules in order of importance 1. Protein with every meal (minimum of 30g) 2. Avoid eating Fats and Carbs together 3. Avoid seed oils If you think about the 3 rules for long enough you'll realise the implications and how many foods you can't consume (and for good reason). The main thing that is removed from the diet is low protein processed foods containing seed oils and sugar together. These hijack you hunger control making it very hard for you to control calories in. When I say avoid fats and carbs together I mean , keep a carb meal low in fat (and vice versa). Avoiding fats and carbs together removes addictive foods such as chocolate, chips, fries, cakes, biscuits, fast foods etc. Two lifestyles that work are High protein, high carb, low fat Or High protein, high fat, low carb. I've tried both of these for long extended amount of times and both work equally as well.

I wish you linked to the studies in the description

Nice!

Best ending ever :)

Candace Owens Anthony B Logan Larry Elder 👂

7:06 "how many time i have to explain this? someone pls halp"

Isn't the reason why the GLP-1 agents cause fat loss due to appetite suppression (which, it would make sense that if your body senses insulin it would imagine there's been a calorie infusion and therefore suppress appetite)?

I am glad I have an English accent. I can say whatever I want in my KZfaq videos and be legit hahah (But I am Bristolian so sound like a farmer lol)

I wish lanyne could dumb it down down abit so I could understand for of what he says, it all sounds great but wtf is he actully saying

4:00 Even if that were true that some people extracted vastly more or less energy from their food, so what? It would still mean that you’d have to find _your_ TDEE and eat slightly less than that. All these people are really arguing against is the idea that you can use an online calculator, eat the Calories it tells you (except when you don’t), and fat loss will be both rapid and guaranteed.

Great video.

When Layne drops the mic... 😂😂😂

11:19 🤣

V-Shreds before every biolyne video lol

Wouldn’t a high insulin rate increase the risk of diabetes though?

Your video title choices are on the wrong side of "triggering" (If that makes sense at all?) IMO. Love the content, just have had times where people didn't care to feed the share and argued against the title only, out of context

What about calorie surplus? With same amound of protein and calories will there be any difference between high carb diet and low carb diet? There are hypothesis that when you are on surplus and have minimum fat (like 30-40g per day) you wont get as much fat as on balanced diet (20-35% fat in diet) ofc with same calories and protein intake. Layne is there any truth or its total BS?

Hi Layne! Could you ever look into doing a video on Philip Goglias method of burning fat, I read his book and he thinks that you dont at all have to go into a calorie deficient diet in order to lose body fat, and making your metabolism work faster is something that will allow you to constantly burn fat! So confusing

Layne, the one thing that I can’t seem to find an answer to is for people who are insulin resistant like my wife. She has PCOS and is at high risk of diabetes due to insulin resistance. Would this change anything? My understanding is that she should eat a low carb/low sugar diet for this reason. I agree with everything you said 100% for the average person. Thoughts?

You criticize the British accent issue re the authenticity of the argument. but you overlook the significance of the piano music plus the British accent. Which in combination proves their point! Plus do a debate with Jason Fung already!

no matter how you slice it , make excuses its comes down to the simple fact that consuming more than you burn leads to weight gain .................many people are in denial

5:24 Are you being deliberately obtuse???? She says that due to fat having 9 calories per gram compared to sugar's 4 calories, there was the mistaken believe that eating fat is necessarily more "fatting" than sugar. This is not a "fallacy" as you say but was a mistaken belief that contributed to the low-fat craze.

too good 😂. The sad thing is that soooo many people eat this kind of shit up and belive it all. Its hard to find the truth, because the truth doesnt make money for products

👊👊

“Big sugar” and “big animal” lol

Bro, your audio is clipping bad..

Could you address this liposomal supplement fad? Like liposomal vitamin c.

Now let's talk about the effects of sugar in the brain, liver or other organs where sugar did cause diseases like non-alcoholic liver disease. Not evening taking into account the effect that sugar has on behavior, I totally disagree with you. Not taking bio chemistry into account is a terrible mistake or even evolutionary medicine.

Like saying a gram is a gram. Tautological. And I enjoyed your comment about the English accent. I'm from Australasia and this particular girly 'let's talk to the morons' tone really grinds my gears.

"He..."

Me, Who lost weight eating ALL of the stuff. "Yeah, Lane's right tbh...."

moooooin meeisteeeer

High carb low fat is bad, low carb high fat is bad, you need to have consistent macros so your body adapts, you need to have variable macros so your body has metabolic flexibility...............

Wait a second? How did the drug increase energy expenditure??

I love all your work but I think that a study or a statistic you referred to a lot is kind of misleading.... You talked about since the year 2000 sugar consumption has gone down in America while obesity has stayed the same but that's because sugar is an added to anything anymore it's high fructose corn syrup. Now I know they act relatively the same in the body, but if the study is referring to just sugar and not calculating the amount of high fructose corn syrup that is taking the place of sugar it's very misleading.

“You can get fucked, eat this”.... fav part

I've been on a high fat diet, moderate protein, zero carb diet since 10/12/2019 and I've lost 40lb...

Why quarantine weight gain is inevitable

you have 1 mea1 to choose from ...500 calories and you reach baseline. Nutella on white bread = 500 calories vs Chicken , rice, veggies = 500 calories ....keep in mind the chicken meal will put you in range for 1 gram per lb of bodyweight for protein. You need to choose between these last meals for 30 days. You're telling me a fitness lifter who's natural see's no difference if for the next 30 days he chooses Nutella sandwich?

i'm first ! not that it matters

AlGoreasaurus

Please limit your audio, it's all over the place.

Roflmao 😂 🙌🏾

Question... Over the last 4 years, I have determined that despite generally being around 78kg, (height - 5 foot 11), I require around 4,500cal to gain any weight, and I require over 5000cal once I get into the 80kg range (at the age of 19 I weighed 59kg before beginning my study, and I tracked my cals obsessively for over 3 years as my weight slowly increased). Although I have never used mass gainer, I do consume a large amount of liquid calories (often around 2500cal per day), through multiple shakes with milk (350ml), milk powder (50g-75g), eggs (3-4), oil (1-4 TBSP), chocolate nesquick, glucose powder. I am just wondering whether liquid calories can partially avoid absorption; hence I can consume around 4000cal and gain 0 weight and sometimes even lose weight... Or whether such shakes with raw eggs and oil have a really high TEF... Maybe processed foods/cheat meals also have a high TEF, hence these don't work well for weight gain? I know I have a really high metabolism as it runs in my family (my brother is 28yr old - 5 foot 10 - weighs 58kgs). However, whenever I tell a nutritionist how many calories I eat, they are often shocked and generally dont believe me; which drives me insane! Any ideas/advice would be massively appreciated, as I have been struggling with this high metabolism since I started training, and its very difficult for me to maintain such high caloric demands each and every day :( (Note: I normally consume around 200g protein, 400-500g carbs, and the rest of my cals from fat) Thanks!!!

Can you do a video on pomegranate juice and a study where it raised salivary testosterone by 24%? Someone sent it to me saying it boosts testosterone assuming it'll act as some kind of "natural test booster". Thanks, Layne!

MORAL OF THE STORY: Do what works for you. Just make sure you get enough protein, and more importantly... make sure you have an accurate idea of how many calories you're consuming/expending. As long as you cover both of those bases, you should be fine.

Sugar intake went down because it got substituted with HFCS.

The "laws of thermodynamics" were created and refer to a much simpler system (steam engines). Seems like a drastic oversimplification to apply them outside of the mechanical engineering they refer to.