3.5 Keys to Improving Mitochondrial Health

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10 ай бұрын

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References (Instructions: Copy DOI number into Search Engine)
[1] doi:10.1076/apab.104.2.129.12878
[2] doi:10.1101/cshperspect.a029686
[3] doi:10.1155/2019/7058350
[4] doi:10.1210/endocr/bqaa158
[5] doi:10.1210/endocr/bqaa158
[6] doi:10.1016/j.biopsych.2018.01.012
[7] Salk Institute (www.salk.edu/news-release/how...)
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Original Video: • Mitochondria - The Key...
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#mitochondrialdisease #mitochondrialhealth #mitochondria

Пікірлер: 354

@Physionic 10 ай бұрын

Here is the first video in this series: kzfaq.info/get/bejne/h75popZ4xK2dg40.html

@PPP-on3vl 10 ай бұрын

FASTING

@ellie698 10 ай бұрын

Excellent! Looking forward to that. I found this video really useful. I have MS and notice that when life is working well so that I feel more positive, I do feel much better. It's nice to see that there's information and data that shows reasons why. It gives me ideas of how to incorporate more good things into my life, little and often and the motivation to do so.

@SkyRiver1 10 ай бұрын

No interest in E5? Amazing. . .

@melvillejayathissa7415 10 ай бұрын

What about supplements to boost mitochondrial health?

@littlevoice_11 10 ай бұрын

And this is exactly why I haven't owed a TV in years! (And don't even miss it). Thank you 🙏 Educating entertainment the Physionics way 😊

@dfung4351 8 ай бұрын

1. Exercise. Both strength training and cardio will help. 2. Fasting (Depends on your diet. All about maintaining 'healthy weight') 3. Be Disciplined about Staying Positive and Express Gratitude. Especially at Night.

@immers2410 3 ай бұрын

Strength training doesn’t really move the needle on this, steady state cardio however is very effective. Read Inigo San-Millan

@johnlakey4983 2 ай бұрын

Well written

@aaaaaa-aaaaaaaaaaaaaaa 2 ай бұрын

which brand and how much does it cost?

@henrymakumbi7753 Ай бұрын

767

@roqclimber 10 ай бұрын

In the evening, my Kitty sits in my lap and purrs, in order to sooth my Mitochondria. Very intuitive animal.

@helenahandkart1857 8 ай бұрын

Cats are tremendously helpful in this way, bless'em!😸

@nevinkuser9892 Ай бұрын

Give that cat a treat

@mjinba07 10 ай бұрын

One of the best and easiest ways to improve mood before bedtime is making a gratitude list - things you're grateful for, whether from that day or further in the past - doesn't matter when. Also doesn't matter whether the list is written or just in your head. The key is lingering in a moment of gratitude. Surprising how many people find it difficult to do at first. It gets way easier with practice, until it's possible to get that warm feeling even when you've had a crap day.

@babyboltbark 7 ай бұрын

FO.

@eastcoastkickz4891 10 ай бұрын

Sleep good, eat better , fast for 12H every day. Lift some weights and move.

@one4320 8 ай бұрын

Stay calm and carry on.

@Bully-mu1su 4 ай бұрын

Eat plants also or carnivore?

@eastcoastkickz4891 4 ай бұрын

@@Bully-mu1su plants too. Get carbs from plants. Like potatoes , sweet potatoes , etc.

@nevinkuser9892 Ай бұрын

Only ever eat fermented vegetables not starch.@@Bully-mu1su

@billa.2940 22 күн бұрын

Meat and vegetables are all you need to improve your health. If you don't like veggies, try saurkraut.

@salleone6387 5 ай бұрын

I just want to share a book from 2010 by Dr. Terry Wahls who reversed her MS to a great degree by concentrating on the health of her mitochondria as the primary focus: 'Minding My Mitochondria'. Its great that researchers are finally catching up after 14 years.

@TaraMae212 9 ай бұрын

The mood-feeling-mitochondrial relationship makes so much sense! Bruce Lipton talks about this is his studies of cell-environment relationships.

@jmc8076 10 ай бұрын

@18:15 This admission alone sets you apart from others on YT and why you’re growing. Humility and curiosity make the best researchers and scientists. Thx Nic!

@Physionic 10 ай бұрын

That I'm a murderer? ;-P Thanks, JMC. Trust me, I never forget I have much to learn.

@jmc8076 10 ай бұрын

Oops, well compliment still applies but not that you don’t already have a lot to teach and share. ✌️

@abc_cba 10 ай бұрын

I use your content these days to make my health tips notebook. Thanks for the immense amount of research you compile.

@Physionic 10 ай бұрын

That's awesome, abc. I'm really glad.

@abc_cba 10 ай бұрын

@@Physionic best wishes from now rainy India heading towards autumn soon 🇮🇳 And my name is Sam.

@Physionic 10 ай бұрын

Autumn here, too, Sam. :)

@sallyweiner4180 7 ай бұрын

My long covid has given me post exercise flat out exhaustion that can last weeks to months. Infrared light therapy, eating right, water, gratitude, community, anti depressants, doing things I love to do that I can physically do and for me this is painting and getting outside is what is slowly helping me. I am trying to get my mitochondria to heal and increase. AND I’ve detached from the news.

@Bait1official 2 ай бұрын

Ray peat baby! Forget low carb. The mitochondria LOVE glucose. The issue never was sugar, if it was our ancestors wouldn’t have sought out honey and fruit. The issue is a mitochondrial one! fix them, fix your disease. ;) Go high carb low low fat. Not forever, for now. We wanna get the body metabolising sugar instead of fat and turn your body in to an energy producing machine so it can heal itself. Kick out PUFAS too.

@vawiley4 10 ай бұрын

I’ve had a shift in focus: Instead of focusing exclusively on how to lose weight, I’m learning how to improve my mitochondrial function I think that focusing on these practices will improve my overall health and the result will likely be multifactorial

@donwinston 10 ай бұрын

Your mitochondria will take care of themselves with regular exercise and a healthy calorie restricted diet.

@r-type4945 10 ай бұрын

Same here. According to Robert Lustig mitochondrial disfunction is the main factor behind insulin resistance. Although there's a strong overlap and interplay, managing weight or blood glucose feels more like treating symptoms than causes.

@mikeo2693 10 ай бұрын

This channel has been a great discovery. Thank you for providing this service.

@dchildr360diurnalnutrition 10 ай бұрын

I greatly appreciate what you’re doing. You provide a valuable resource to those of us wishing to learn more.

@heyyou9839 10 ай бұрын

The issue with PhD scientists is that they take their laboratory subject “mitochondria” and study and make recommendations outside of the rest of the body. If you eat in a way that is a calorie deficit, with many anti-inflammatory compounds, and increase fasting window PLUS move more PLUS sleep enough - that will help a raft of different processes such as hormonal responses to food, your body composition, and your stress pathways, which will sure probably have flow on effects to intercellular organelles including mitochondria. The constructs that focus on one particular aspect of the body are spurious

@07.buddhi 10 ай бұрын

Nicolas, please make a video about supplements that really help with mitochondrial health! Such as Q10 as an electron transporter and other interesting things 🙌🏻 Maybe about cellular respiration and overall more basic bioenergetics stuff 🤓 BTW like your work a lot! Keep it going! 🙏🏻

@teddybearroosevelt1847 10 ай бұрын

Here are a few more: pqq, d-ribose, creatine, alpha lipoic acid, cumin seeds (you need to grind them or chew on them to have a chemical released that I would have to look up but that supports the mitochondria)

@melvillejayathissa7415 10 ай бұрын

Also the UBIQUINOL supplemental form of CoQ10 as well, for adults over 30 years of age! Melville from sunny Malaysia

@bejul2 9 ай бұрын

As a chronic fatigue suffer - I can tell what supplements really have a good effect. And these are ss-31, mots-c, methylene blue, tudca (so far tudca is the best for me)

@zahram4473 9 ай бұрын

Can you please share supplement names and brands?

@martinlang9615 8 ай бұрын

@@bejul2yes, please mention brands as I too suffer chronic fatigue

@TsuchiuraBob 10 ай бұрын

Just a peripheral comment on the importance of neuromuscular junction (NMJ) maintenance in enabling exercise. An NMJ is the synapse between motor neuron and muscle fiber. There are genetic diseases as well as inevitable aging that cause the motor neuron to die back, causing fewer muscle fibres to fire, in turn weakening the muscle. Much remains unknown about this process that leads to sarcopenia (muscle weakness in the aged), but it would come as no surprise to me if mitochondrial health turns out to be one of the players in this process, possibly setting off a vicious cycle of weakness discouraging exercise, in turn leading to more die-back of motor neurons.

@gabriellew6467 10 ай бұрын

Most subscribers will probably agree with abc - but let me add that apart from informing intelligently and discussing knowledgably, you do it with the most delightful touch of humour. You are to serious information what yeast is to bread - making it lighter and more palatable 😊

@karenf9137 10 ай бұрын

Great analogy.

@Physionic 10 ай бұрын

That's really kind of you, Garbielle. Thank you.

@gaiacielo5090 9 ай бұрын

Yes this should go out to more people! Been following people talking about mitochondria health! Thank you good sure 👌🏾 😊

@H4KnSL4K 10 ай бұрын

Thanks for highlighting details of our incredible design!

@ambrsanford3703 10 ай бұрын

I am actually retaining this stuff. Thanks, again!

@AnneAlready 10 ай бұрын

Thanks for featuring Martin Picard and breaking down and expanding on some of his insights. Great video.

@reggie5 10 ай бұрын

10:51 very interesting, particularly what you said about mitochondria downsizing in response to a nutrient overload. I've heard people say to continue your supplement regime during fasting - but maybe it would be more beneficial to discontinue the supplements during a 24/48 hour fast to freak the mitochondria out a bit more? rather than keeping them relatively comfortable despite the lack of food intake.

@flcps 4 ай бұрын

That's what I do in my weekly 48 fast. Nothing besides water, black coffee and a bit of water kefir

@antoniakotsiros2836 9 ай бұрын

Thank you so much for your amazing video. Loved every minute and can’t wait for part 2. Have an amazing day 🎁🎁🌟🥁

@casta9172 9 ай бұрын

Thanks for this information ❤ I'm battling cancer and I need to know more about mitochondria

@rahvastepaabel 6 ай бұрын

Study cancer metabolic treatment options, youre mind will be blown

@HazardousHumorHQ 9 ай бұрын

Good work sir. A key takeaway from a latter part of the video, re: sleep, stress, mitochondria...for ⬆️ A.M. ENERGY, optimize stress PRIOR to sleep! Work towards consistently better mental mood prior to sleep time! Makes sense...emotionally better state during sleep onset --> more PNS-activated state during sleep onset --> positive neuro-emotive inertia starting out--> momentum carries through subsequent sleep cycles to some extent, perhaps facilitating (for example) better dreams and so on. Anyway, I'm sure findings in the field of psychoneuroimmunology would agree! Keep it up Physionic, and let's all take care of our emotional, cognitive and overall mental health and resilience, folks!

@SquatFull 10 ай бұрын

Thanks for the information on the mitochondria and the references to the studies.

@Chaotic313 10 ай бұрын

The interweaving of science and humor in your content is sublime. More? Yes please. ❤

@Physionic 10 ай бұрын

Deal!

@tobiasgarrard9271 7 ай бұрын

It's amazing people like you that make a difference with us humans. Thanks for being a great one. Keep studying and sharing⭐

@lostinversailles 10 ай бұрын

Aha! Suspense - more to come in part 2! What a science opera 😁

@Bepartofthepanacea 9 ай бұрын

Amazing work and explanation 👏 thanks ❤️

@Johnnysday 10 ай бұрын

You offer tremendous service to that greater body of knowledge.

@abdelilahbenahmed4350 10 ай бұрын

Thx Physionic for this another great video. May I ask you what are your thoughts on the impact of metformin on the mitochodria. Some people say it's a mitochondrial poison, but a pretty large number of studies indicate that it increases mitochondrial biogenesis. Other researchers say that even if metformin impacts the mitochondria negatively (but slightly) it's actually a good thing because it triggers the mechanism of hormesis in the body. Excited to see how you could clarify even a litte bit this complex topic.

@HazardousHumorHQ 9 ай бұрын

Thanks for your work!

@MarcoBrianza 10 ай бұрын

Hi, great content as usual. I just watched it during my 20 min morning bike (fasting) exercise to start the day and apparently to multiply my mitochondria. I constantly stumble upon the effect of red/infrared light on the cell even on energy production. Is it something you plan to cover in the future?

@vajaindransramasamy4107 9 ай бұрын

Fascinating information. Thank you.

@mitchellgould2053 10 ай бұрын

Great video, as usual. Have you by chance looked into any of the work Cohbar is doing with mitochondrial peptides?

@user-hn3qc3oh5r 10 ай бұрын

being able to measure mitochonrial health and population is amazing, everyone knows extrinsics like emotion have everything to do with how we feel, now backed by this most fascinating area of research,, thank you for sharing this! you're a good man!!, despite having admittedly commiting murder in your lab

@Resist.Tyranny 5 ай бұрын

Avoiding poisons and toxic substances may not be revolutionary, but someone understanding how prevalent these harmful substances are, and actually avoiding them is very rare. When umbilical blood was tested for toxins from many mothers births, OVER 200 chemical toxins were found.

@TheEngadine 10 ай бұрын

I feel proud of promoting you, Nicolas and this, your channel in each and every antiaging forum I follow. Hope it helps you and your team to reach your goals in YT. Big Thank You. 🎉

@Physionic 10 ай бұрын

Really kind of you. Thank you. :)

@carlribbegardh2723 10 ай бұрын

Ooh, this is going to be good 😊

@mrkevinj 9 ай бұрын

This is so helpful!

@mpicar2 9 ай бұрын

Great summary - well done

@AlexanderGolovatiy 10 ай бұрын

Thank you, Nickolas 🌞

@truop4110 10 ай бұрын

Now that's sn amazing video ❤

@littlevoice_11 10 ай бұрын

I wonder how issues such as chronic digestive issues such as IBS, SIBO, leaky gut etc impact mitochondrial health. I am aware these can impact mental health through the gut brain axis.

@JuanLopez-sx1er 7 ай бұрын

MARVELOUS Video THANKS DR 🧑‍⚕️🙏

@AlexHop1 9 ай бұрын

Thank you, very helpful!

@arthurdolle5257 10 ай бұрын

Very informative discussion with information I haven't seen anywhere else. Do you think keeping a stiff upper lip through adversity helps mitochondrial function?

@rookhoatzin 9 ай бұрын

A positive attitude improves your biological function. We know that intuitively but I love to hear it from a scientist in the know....

@sheradenart7907 3 ай бұрын

Oxytocin is connected to mitochondria, it helps balance the need for iron in electron transport and OXPHOS. So it makes alot of sense that happiness would be connected to mitochondrial health.

@rosaflorpuig3971 10 ай бұрын

Looking forward to your “senolytics” video. Please include “Qualia Senolytics” contentions that their 2-day regimen actually cleans out zombie cells. Thank you.

@FlowerlyF. 10 ай бұрын

So interesting! 😊thank you

@littlevoice_11 10 ай бұрын

Id love to hear more about mitochondria in relation to MS and post viral fatigue or fibromyalgia

@teddybearroosevelt1847 10 ай бұрын

Mitochondria play a role in almost every disease, as they do much more than just provide the body with energy

@mike7920 10 ай бұрын

Alex Howard in his book Decode Your Fatigue goes into depth on this

@hoffmancapote 10 ай бұрын

Thanks Nicholas for a great video. I do not comment a lot on your videos but I find it inspiring that you rely on research and not mutated opinion to make your videos. Your humorous comments are also improving

@Physionic 10 ай бұрын

I appreciate that!

@ijimstopit 10 ай бұрын

Again, another information filled science lesson entertainingly delivered.

@mikeward9870 10 ай бұрын

Nice! One key concept that is often missing in metabolic vids (keto, ...) is that fasting/hunger (to generate mitochondria) is more than endogenous use of MCT oil (with abundant nutrients).

@SA-jo1pz 7 ай бұрын

Love your info.

@sleeplessforawhile 10 ай бұрын

No magic for now... but as always... great job to giving us a real landscape about mit. Just one question, talking about how phisical activity could increat mit. account... is there any study about how "mental activity" could induce similar process about increaing mit. account but in neurons?. Thank you so much for sharing you work. PD. I´m quite interested on PQQ , do you have in mind to do any video about it?.

@romz1 10 ай бұрын

Interesting, thanks 👍

@thetranscendedman 10 ай бұрын

I've heard people use inversion to talk about "not poisoning the body" when it comes to eating junk food, not exercising enough, not sleeping enough, etc. Perhaps we should extend that definition to the powerhouse of the cell!

@danhanks2936 9 ай бұрын

Thanks I like your science approach to health. There are a lot of questionable ideas floating around cyber space. This is an amazing time to be alive with so many wonderful people investigating our world.

@MichielMortier 10 ай бұрын

And what about the additional use of CoQ10? As often used extra with statins? Do you notice results right away?

@finalfan321 10 ай бұрын

great video

@eltarahim5859 9 ай бұрын

You are delightful! Learned so much..thank you sunshine!! Sending love from LivelyLasVegas!!

@billtrudell1636 19 күн бұрын

Martin is a great guy I've learned so much from him.

@jeno427 10 ай бұрын

Very informational video. Would you consider making a video about exercise adaptation and antioxidants? Ubiquinol is an antioxidant yet it increases mitochondrial biogenesis, which is seemingly contradictory. There is not much info on it other than the bro science avoid antioxidants a couple hours before and after exercise.

@a_bar8579 10 ай бұрын

We wish to translate this teacher's channel so that all languages can benefit from it.

@joerockhead7246 10 ай бұрын

thank you.

@aboto0oti 10 ай бұрын

Thanks ❤️❤️

@salvadoroliveira6632 10 ай бұрын

Greetings; a book by Dr. Bodo Kuklinski, " Das HWS-Trauma: Ursache, Diagnose und Therapie " mentions something about how mitochondria are related with the physiology in certain conditions; I skimmed through pages years ago ( the book wasn't mine ) and I'd like to ask if anyone knows a version of that book in english. Thanks!

@salvadoroliveira6632 10 ай бұрын

Conventional agriculture usually uses fertilizers that contain N, P and K; the continuous maintenance of crops deplete soils and the fact that nobody. " makes number 2 " out of a toilet, prevents the recycling of minerals on soils. Is magnesium added to commercial fertilizers? Many enzymes cannot work without enough magnesium intake.

@nieczerwony 10 ай бұрын

Well this is the charm of industrial farming which is more and more spread and supported by politicians worldwide.

@DesertDog8989 10 ай бұрын

and many who take magnesium don't check their copper; this balance is critical ❤

@nieczerwony 10 ай бұрын

@@DesertDog8989 I know people who take 30 mg or more zinc a day (as they heard that zinc= better immune system), and they don't even care about taking copper and selenium. So yeah I don't expect them to do the same for magnesium

@salvadoroliveira6632 10 ай бұрын

@@DesertDog8989 Does the ingestion of magnesium affect the level of copper in the body? Or do you mean that people should also check for the level of cooper? Thanks.

@fyrerayne8882 3 ай бұрын

thank you

@michaelstreeter3125 10 ай бұрын

15:37 There's a book, Kahneman, D. (2011) *Thinking, fast and slow.* 2nd edn. New York: Farrar, Straus and Giroux. where he says question order is super important; if you ask (1) how happy do you feel? then (2) do you have a girlfriend/boyfriend at the moment? you get _completely_ different scores compared to asking the same questions the other way around. Because "do you have a girlfriend/boyfriend?" gets the subject thinking and sets them up for the next question.

@enzogaibisso9691 10 ай бұрын

@18:12 love your humor and your content

@trishnardone6187 Ай бұрын

Thanks!

@pip5461 10 ай бұрын

Could you put your analytical expertise into the study of Tinnitus...?

@sncnutrition7118 10 ай бұрын

Yes!!

@pip5461 10 ай бұрын

Thank you...@@sncnutrition7118

@drunvert 10 ай бұрын

👍

@JimWeaverFeb11 10 ай бұрын

Thanks

@jamescalifornia2964 10 ай бұрын

😉 May all your mitochondria be healthy 🙏 ✨️

@claudiomicheli3863 10 ай бұрын

Is mitochondrial fission inherently bad for energy metabolism? Its function is to only dissipate the excess energy? Can the newly separated mitochondria grow in size to match the previous mitochondria after the fission?

@AnP865 5 ай бұрын

It's cool that you're keeping things complicated. Some of the mitochondria people are alluding to or even explicitly stating a level of simple certainty which doesn't seem valid, more like ideology.

@Appleblade 10 ай бұрын

Fred Hatfield's book, Bodybuilding: A Scientific Approach, had a section claiming (and citing studies, if I remember right) that mitochondria increase mainly when you stress muscles with 20+ slow reps... 90+ seconds of continuous tension... IOW, anaerobically (sarcoplasmic reticulum increases with 10-12 reps, actin & myocin increase with 4-6 reps). Has this information been lost among researchers? Was it speculative? IDK

@petebarnes1525 9 ай бұрын

Interesting video, thank you. I will study more about Mitochondrial health, how to improve it, and how to avoid worsening it.

@fastingcoach9711 9 ай бұрын

Eat less Move more

@Korvxx 9 ай бұрын

20:20 what fat source? I feel great with coffe and cocoa butter early in the day, pure fat and the stearic acid is good for mitochondrial fusion as well?

@h0ph1p13 10 ай бұрын

Please make a video about salt (yes, NaCl). It's a very controversial topic. I read "The Salt Fix" and "Salt Your Way to Health" both present a very interesting picture. I wonder what's your take on salt in our diet and also salt as a supplement for endurance exercise and muscle strength.

@jenn1663 10 ай бұрын

Also, I had this question on one of your other Mito videos, but thought I would also put it here. Quick question, and I don't if anyone knows the answer to this or not. But under long periods of time do the mitochondria appear to be affected by selective forces? Meaning, is there some kind of competitive evolution going on between the mitochondria in any given cell? Let's say a cell is bombarded with constant over-nutrition, are the mitochondria that can handle the over-nutrition better the ones that survive this process and continue to replicate? If so does that mean you may end up losing mitochondria that do not handle the over-nutrition (over a long period of time)? And if that is the case, what happens when someone intentionally tries to lose weight or is in a starvation environment? I would expect that the current mitochondria would attempt fusion and elongation, but how good are they at it after several years of over-nutrition? Meaning, would ATP generation in a starving person (who was previously in a long-term over-nutrition state) be compromised and insufficient not only because the current mitochondria are in a state of intentional inefficiency, but also because over time those mitochondria have been selected for their ability to handle the over nutrition state? Is there now a permanent bias toward inefficiency even after fusion?

@FORTRAN4ever 10 ай бұрын

I have read articles that connect the dots about ME/CFS symptoms being brought about from some mitochondrial dysfunction . It is hard to imagine increased aerobics improving a ME/CFS patient's symptoms when doing so results Post Exertion Malaise (PEM).

@id9139 Ай бұрын

Yes, correct... What is the solution?

@surajitgoswami1871 8 ай бұрын

Independent of glucose is my conclusion too using a sample size of one. To redress then fasting may improve mitochondrial health in addition to reducing food overload. Thanks.

@bredmond812 10 ай бұрын

At the beginning of the video, you mentioned your original mitochondria video. I want to watch that video, but with a search, it seems you have several "mitochondria" videos. What is the specific video you are referring to?

@yay-cat 10 ай бұрын

With the feelings study. I wonder if they took menstrual cycle into account. Like I feel a bit more depro in my luteal phase (2 weeks after ovulation). But like I would think the cocktail of hormone interactions over this cycle has a larger effect than the mood. Like it might be correlation not causation

@AbidAli-bv2gl 5 ай бұрын

well done

@paulpellico3797 10 ай бұрын

so everything we need to know we already learned in kindergarten??? move, play, eat well....be kind.

@Link-ny9xz 4 ай бұрын

My niece has LHON. Can you share some info to help her? Would keto help?

@elvistrompf317 10 ай бұрын

These summaries are great, even for those with acquired mitochondrial disorders. I have Friedreich's Ataxia, and the research is pretty sparse,and so are the treatments. The data available does suggest what works for acquired disorders works for FA to some degree

@Burnrate 10 ай бұрын

It's like having a ton of engines running at low rpms is better than having a few engines running at high rpms and overheating to do the same work. If you have too much fuel being dumped in all the time your body will remove a bunch of engines leaving you with few engines.

@lynnwilliams5432 10 ай бұрын

Normal weight but osteoporosis 81 yrs on cane fracture femur stem . Anterior hip replaced 10,000 steps 4 miles today going out once more to get up hill cardio. Was sprinting bf fractured occurred picking up trash. Do weight arms shoulders grip.

@ericmaclaurin8525 10 ай бұрын

I'd argue the primary difference between damaged or mutated is that one is best fixed by helping the body fix itself. Mutated means your body would literally break it again if it had its way so you have to fix the mitochondria and then block the bodies mutated mitochondrial maintenance network.

@ThomasAT86 22 күн бұрын

Dealing with severe ME/CFS, these things sadly didn't do anything and that's true for almost everybody with this illness. I hope there's WAY more research coming out in this regard. Desperate to not lose another decade.

@jenn1663 10 ай бұрын

Is this one way that taurine supplementation/exercise that increases taurine levels might be helpful in mitochondrial health/longevity? "Taurine deficiency and rotenone actions are similar, as both lead to reductions in complex I activity, inhibition of NADH dehydrogenase activity, reductions in respiratory activity and elevations in NADH. Because a primary physiological function of taurine is the maintenance of complex I activity, there is reason to believe that taurine therapy should reduce the severity of Parkinson’s disease (Alkholifi et al., 2015). "

@PaulHigginbothamSr 10 ай бұрын

Just let me say when younger my night vision was not as good as it is now. For 3 months I have been taking a supplement of taurine. I am taking 1,000 mg and have experimented with 2,000 mg on an occasion where I wished to check my night vision and it was reduced by doubling the dose. Before taking taurine at all I could see down the path 1/2 mile clearly. After taking taurine it was like everything was shut off beyond my bikes headlight beam. I could see all the way to the end of the walk clearly before taking taurine. What makes me wonder is my natural level of taurine being higher when younger reduced my night vision. I am seriously considering stopping my use of this supplement. I wish I knew the chemical reason for this reduction. I walk my dog early before light in the morning and have heard curious things in the dark. I am now 75 and many blood components have reduced significantly as I age further but night vision increase was not expected.

@helenahandkart1857 8 ай бұрын

Very interesting.. i've always had poor night vision, & it unexpectedly improved after about 18 months of drinking 300mls of cold vaccum pressed raw full cream Jersey milk, daily. I think it may possibly've been the extra bioavailable retinol.🤔

@salvadoroliveira6632 10 ай бұрын

Can tetracyclin affect human mitochondria?