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Please do not use this footage without my expressed permission.
The following clips are of my horse Deuce experiencing HYPP episodes throughout the years. His status is N/H.
Here is how I would describe HYPP:
Hyperkalemic Periodic Paralysis (aka HYPP) is an autosomal-dominant genetic mutation disease that effects the sodium ion channels of horses, and are often characterized with a muscular appearance. Horses with this disease are known to be decendants of the 1969 appendix stallion "Impressive". Although, it has been said that his dam, "Glamour Bars", was truly the one responsible for the introduction of HYPP, as she had foaled 2 others with the disease that had no relation to Impressive.
Horses with this disease can be tested with a 5 or 6 panel test by sending their root hair foilicles to a genetic testing lab. There are three possible results: N/N, N/H and H/H. N/N horses are completley uneffected by the gene. N/H horses are heterozygous and carry one copy of the gene. H/H horses are homozygous and carry both copies of the gene. N/H horses can be just as symptomatic as H/H horses due to the gene being autosomal dominant.
Symptoms of this disease may include: muscle tremors or involuntary muscle contractions, sweating, feverish or dull attitude, prolapse of the third eyelid, loud breathing noises, muscle weakness, tying up, collapse, and cardiac arrest/respiratory failure.
Causes of the attacks are due to abnormal function of sodium ion channels. When an excess amount of potassium is present, the sodium ion gates stay open, allowing the excess to flow into the blood stream, causing involuntary contractions.
Treatment of the disease include a low potassium diet (less than 1% potassium in an entire day, including all forage, grasses, & concentrates, or less than 33g of K per meal) and a low stress enviorment/lifestyle. Avoiding high potassium feeds such as kelp meal, molasses, pink salt, alfalfa or orchard grass, soy meal, and electrolytes. Foods that may benefit are white salt, oats, barley, corn, and timothy hay. It is best to feed small, frequent meals to stay within potassium limits. Soaking hay may also be beneficial, and turnout is very important. Access to clean water at all times is most important. The use of acetazolamide is often a reliable treatment aswell.
-Olive Shupe
Dr. Lydia Gray's most recent research about HYPP
• No. 306. Dr. Lydia Gra...
UC Davis on HYPP
vgl.ucdavis.edu/test/hypp
Mad Barn about HYPP
vgl.ucdavis.edu/test/hypp