Gene Editing Inside the Body Using CRISPR

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4 жыл бұрын

CRISPR-Cas9 technology is used to edit DNA to correct genetic abnormalities, but until now has required cells be removed for gene editing outside the body. In March 2020 researchers announced a test of the first in-the-body (in vivo) CRISPR-Cas9 treatment for Leber congenital amaurosis (LCA) type 10, a condition that causes severe, early-onset vision loss. This video explains the principles of DNA editing with #CRISPR-Cas9 and the rationale for its use and testing as a therapy for LCA10 in the BRILLIANCE clinical trial. Click ja.ma/35adPDf to read a #JAMAMedNews review of the range of clinical trials testing CRISPR as a treatment for genetic blindness and other human diseases in 2020.

Пікірлер: 30

@JAMANetwork 6 ай бұрын

Click ja.ma/35adPDf to read "With First CRISPR Trials, Gene Editing Moves Toward the Clinic" in JAMA.

@averyherren7366 3 жыл бұрын

an amazing process thanks to modern science. A great thanks should be awarded to the patient for undergoing such a controversial procedure. Their contribution to science pushes us forward in spite of uncertainty

@DCassidy42 2 жыл бұрын

I have hypertrophic cardiomyopathy and I hope that they can come up with an effective treatment for all genetic diseases. Most genetic diseases cause so much suffering without any treatment.

@popkinbobkin Жыл бұрын

Well, how did it go?

@lucyk2371 3 жыл бұрын

This is so amazing. It's a miracle... We have to be very careful. What a blessing. I'm hoping that this can eventually cure inherited forms of cancer.

@JRay2113 2 жыл бұрын

One of the best explainers for crispr-cas9. Bravo 👏🏼

@WaltRBuck 4 жыл бұрын

Wow wow wow!! This is amazing!

@heikkipalola6760 3 жыл бұрын

@Website guy aren't you the arrogant one if you think you know what's going on better than the majority of people.

@LabadMostafa-uf5rk 5 ай бұрын

Please I want to know where the CRISPR Cas9 experiments on alopecia have reached

@__________6597 3 жыл бұрын

Is possibile build nanotecnology medicine for kill cancer or infections? Tx

@burung81 8 ай бұрын

How is the trial result? pls help to update/follow up?

@rahulpaul2976 3 жыл бұрын

Is it possible to change skin color by using crispr tecnology??

@rosieposie2331 3 жыл бұрын

Amazing ....hope it works! 🤞🏼

@paulinetayloe9988 Жыл бұрын

If one person was to use crisper cas 9 on themself for experimental reason would it kill that person? Is it safe to do that? Just asking I’ve never and not going to do that just wondering.

@kitkatcass8509 8 ай бұрын

Oddly enough, they sell kits online to try on bacteria. You gotta know what you're doing and fully understand the process. You don't want to go around editing the wrong areas of your genome. I guess if someone had the funding to afford further necessary equipment and a staff to assist, they could. I'm studying biopsychology for this very reason. To do research and maybe work with cas9.

@azoor5881 4 жыл бұрын

I thought this medication, luxterna, was already available and fda approved? The information in this video appears out dated but it says the video just came out last week?

@JAMANetwork 4 жыл бұрын

Luxterna is gene therapy. This describes a gene editing intervention - different approach.