L-Tyrosine and 5-HTP: Do you NEED to take them together?

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Dr Janelle Sinclair

Dr Janelle Sinclair

Күн бұрын

Interested in resolving depression and anxiety naturally?
Check out Dr Janelle’s online course Real Relief Foundations. www.drjanellesinclair.com/eco....
Download my symptoms checklist to undercover the biochemical cause of your depression and anxiety: www.drjanellesinclair.com/resource
Are you questioning whether you need to take l-tyrosine and 5-htp together? Some people are saying that if you take 5 htp for depression, that you’ll make your symptoms worse if you don’t take 5-htp and tyrosine (5-htp l tyrosine).
In this video Dr Janelle talks about how dopamine and serotonin are made in the body, serotonin deficiency and dopamine deficiency symptoms. She discusses the impact of taking l tyrosine for depression and 5-htp for depression, on their own and together. Tyrosine supplements can increase the activity of the AAAD enzyme and led to reduced serotonin levels. This doesn’t happen with tyrosine rich foods.
Near the end of the video 5-htp dosage for depression (5-htp for depression dosage) and tyrosine dosage for depression are discussed.
If you’re looking for a video about how much 5 htp for depression, 5-htp dosage, 5 htp dosage, 5-htp and depression or 5-htp depression check out this video on that topic: • 5-HTP dosage for depre...
Here’s the scientific research that I refer to in my video: www.ncbi.nlm.nih.gov/pmc/arti...
FOR MORE INFORMATION!
Subscribe to this KZfaq Channel to watch more practical videos on natural medicine (testing, supplements, diets & detox) for depression and anxiety.
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Website: www.drjanellesinclair.com
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*Dr Janelle Sinclair received her PhD in biochemistry from the University of Basel, Switzerland in 2003. Her use of "doctor" or "Dr." in relation to herself solely refers to that degree. Dr Janelle is a licensed natural health practitioner in New Zealand. The content contained in this video is strictly the opinion of Dr Janelle Sinclair, and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. It does not create a doctor-patient relationship between Dr Sinclair and you. Dr Janelle nor Conscious Health Ltd are not liable or responsible for any possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content should seek advice from a physician or qualified health provider with any questions you may have regarding a medical condition or interactions of supplements with medications. This description may contain affiliate links.

Пікірлер: 672
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
Register your interest in my online course- Real Relief: The natural approach for resolving depression and anxiety. www.drjanellesinclair.com/ecourse
@Calaman345
@Calaman345 4 жыл бұрын
This was 🔥... please continue to dive into neurochemicals more Dr. ❤👍🏼💯Appreciate your work
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
@@Calaman345 thanks Cal. Any particular topics you're interested in?
@Calaman345
@Calaman345 4 жыл бұрын
@@DrJanelleSinclair Dopamine.. dosage, intake, studies on supplementation of precursors to dopamine.. Oxytocin...how to increase with supplementation, increase naturally. Pros and cons of having high or excess Honorable mention: Cortisol, NAD+
@compostcorner5934
@compostcorner5934 4 жыл бұрын
Hi Janelle, I have just bought some L Tyrosine and 5htp.. My question is can I take these with Tramadol... Long story short. I'm trying to get off the tramadol as my back pain has fortunately now improved, the problem is I had become addicted to the tramadol, so Iv been having to take it, just to feel normal So my plan was to eventually get off the tramadol completely with the help of l tyrosine and 5htp. Thank you Tony
@macIain
@macIain 4 жыл бұрын
Dr Janelle Sinclair, can we take these supplements continuously on a long term basis or should we just take them for a certain amount of time?
@pskelton1000
@pskelton1000 4 жыл бұрын
She begins to answer the question 3 minutes in...fast forward.
@becomingfr33
@becomingfr33 4 жыл бұрын
Thanks for giving me 3 mins of my life!
@spiikedude
@spiikedude 4 жыл бұрын
You sir, are the hero we are all looking for
@jmiogo
@jmiogo 4 жыл бұрын
Thank you
@DonCannone
@DonCannone 3 жыл бұрын
I should have went to the comment section first. It was painful
@avatar1867
@avatar1867 3 жыл бұрын
My hero
@zianawind2970
@zianawind2970 4 жыл бұрын
I really appreciate how thoroughly implemented delivered this information is. There are so many less informed not professional you tubers talking about nootropics and though it’s good to get the word out it’s nice to hear from someone that has more than 3 months experience! I’m definitely subscribing thank you for sharing information about this things in a trustworthy coherent way.
@Solami987
@Solami987 4 жыл бұрын
Thank you for this info! The internet is overwhelmed with this idea of needing the two together. I personally think I need both, especially after trying L-tyrosine 1 week into starting 5htp. Your guideline recommendations are spot on. I made the mistake day 1 of trying L-tyrosine with 5htp at night and my sleep was not great, as you mentioned might happen.
@pratiknaikedu
@pratiknaikedu 4 жыл бұрын
Thank you SO MUCH for this! It's been really helpful! Please keep producing great content you are easy to listen to!
@emankcineht497
@emankcineht497 2 жыл бұрын
Such a clear but also detailed explanation, just what I was looking for. Thank you, you doing really good job here!
@paolosoriani2106
@paolosoriani2106 Жыл бұрын
Finally a comprehensive and clear explanation, thank you!
@jmiogo
@jmiogo 4 жыл бұрын
3:12. She finally stops telling you what she’s going to tell you and tells you.
@Ds4u2
@Ds4u2 4 жыл бұрын
Gotta extend the video to 10 minutes to get dat youtube money baby
@ionseven
@ionseven 3 жыл бұрын
Thank you
@DrJanelleSinclair
@DrJanelleSinclair 2 жыл бұрын
@@Ds4u2 there's no ads on any of videos. I make no money off them
@kylegraham9794
@kylegraham9794 2 жыл бұрын
@@DrJanelleSinclair do you take them at same time as each other or space out when you take the 2 supplements? Thank you.
@keylatellez8054
@keylatellez8054 2 жыл бұрын
@UCKV4zHO9ImKYRahFXHmcoxw wtf are you talking about itch
@robturnlund1529
@robturnlund1529 3 жыл бұрын
Interesting video, my husband was diagnosed 4 years ago with FTD and he has had insomnia chronically and foggy headedness during the daytime. I started him on 5htp and he has improved significantly with better sleep and increased energy and the brain dig has cleared completely! Interesting also his chronic sinusitis has resolved and he can smell again for the first time in decades. Don't know if it is curative but it sure has improved his quality of life!
@DrJanelleSinclair
@DrJanelleSinclair 3 жыл бұрын
Wow that's an amazing change with just 5htp.
@trulydivin3
@trulydivin3 4 жыл бұрын
Her Answer: 5-HTP is fine alone.
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
For some people, but not for others. 👍
@deni32biberic9
@deni32biberic9 4 жыл бұрын
@@DrJanelleSinclair Hi Dr Janelle.sorry.Can I drink 5HTP and L Terosine together? Thanks
@glaubermarcius
@glaubermarcius 3 жыл бұрын
Thank you! A prolix video, just to say a simple assertion. Bet she is not MD.
@DrJanelleSinclair
@DrJanelleSinclair 3 жыл бұрын
@@glaubermarcius no I'm not an MD and I tell everybody that. I've got a PhD in biochemistry.
@DrJanelleSinclair
@DrJanelleSinclair 3 жыл бұрын
@@deni32biberic9 yes you can
@brisha.j
@brisha.j Жыл бұрын
Oh my god finally I just found this video I been so curious and I was just launching around on here so I’m happy I found this thank you for coming out and talking about it doctor
@mcelroyj2758
@mcelroyj2758 4 жыл бұрын
Thank you for the information, Dr. Sinclair! Wonderful videos!
@imcrazyo
@imcrazyo 4 жыл бұрын
this channel is awesome. thanks so much for the thoughtful information
@missnerd4832
@missnerd4832 2 жыл бұрын
Thanks for this! I stopped with my ADHD meds and am now taking tyrosine (650 mg), vitamin B complex and omega 3 in the morning and 5htp (100mg) at night. Perfect combo!
@PM-tk3se
@PM-tk3se 2 жыл бұрын
Yay. Happy for you. Cool to hear that it works
@tapatot541
@tapatot541 2 жыл бұрын
What’s the brands ?!
@csgotunibetprediciton4019
@csgotunibetprediciton4019 2 жыл бұрын
@@tapatot541 just make sure they dont add shit in the supps then you should be fine i guess..
@safvanchenathsafvan980
@safvanchenathsafvan980 2 жыл бұрын
For what
@marijazlatar5457
@marijazlatar5457 Жыл бұрын
You use too much.It must be 1:10. 5HTP in morning 50 mg and Tyrosine in evening 500 mg with other suplement b komplex cooper magnesium to better absorpcien.
@munirobeidat7433
@munirobeidat7433 4 жыл бұрын
These videos are very helpful, please continue posting please
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
Thanks Munir. I'm back to posting weekly now after a break. Glad they are helpful for you
@gailhowes9398
@gailhowes9398 2 жыл бұрын
I have Parkinson’s disease plus MSA for 22 plus years,so I am very pleased by your videos and I have every symptom you listed! So I have changed my supplements that will help me from what you suggested. Thank you so much!
@Ayrad160
@Ayrad160 2 жыл бұрын
I hope you are doing better.
@littlelulu4107
@littlelulu4107 4 ай бұрын
Have your symptoms improved?
@OyaRevolutionary
@OyaRevolutionary Ай бұрын
Thank you for your help and time committed to helping 😊
@villagegreenapothecary9946
@villagegreenapothecary9946 2 жыл бұрын
Great video with a lot of good information. Thanks for sharing!
@jaredking2473
@jaredking2473 3 жыл бұрын
Love this. You really answered all the questions
@DrJanelleSinclair
@DrJanelleSinclair 3 жыл бұрын
Fantastic!!!! If you need more answers about how to heal depression then check out my free webclass www.drjanellesinclair.com/webclass
@kangaroobrisket6118
@kangaroobrisket6118 3 жыл бұрын
Thank you for this information!!!! I have been taking both. Now I'm going to just try 5-HTP. I'm hoping I could cut out the Tyrosine. Thanks again Doctor. You are smart and pretty.
@DrJanelleSinclair
@DrJanelleSinclair 3 жыл бұрын
Thanks I'm glad it was helpful. If you need any further help with depression or anxiety check out my online course Real Relief Foundations. www.drjanellesinclair.com/ecourse. It provides a comprehensive natural approach to improving mental health
@manchester8143
@manchester8143 Жыл бұрын
This video worth to watch. Thanks doc
@chlecziferryn2895
@chlecziferryn2895 3 жыл бұрын
It's probably good practice for psychiatrists to test their patients for low serotonin and dopamine levels and prescribe them nootropics(5htp, l tyrosine, l theanine, st johns wort, etc.) instead of man-made medicines that have really bad side-effects and withdrawals.
@mansakonko7777
@mansakonko7777 2 жыл бұрын
The only medical professional who doesn't look at the organ they treat....apart from behaviours. Brain scans, blood work should be part and parcel of the psychiatry modality.
@dr.ngoziibe3583
@dr.ngoziibe3583 3 жыл бұрын
You are helping lives. Thank you.
@DrJanelleSinclair
@DrJanelleSinclair 3 жыл бұрын
Thanks Dr Ngozi for the encouragement. It means a lot
@evandugas7888
@evandugas7888 Жыл бұрын
I recently learned the new topic people have real research...
@reneehaber2066
@reneehaber2066 4 жыл бұрын
Excellent explanations! Thank you!
@sacredholly
@sacredholly 3 жыл бұрын
Thank you! This was really helpful. :)
@keelyleilani1326
@keelyleilani1326 4 жыл бұрын
I'm doing 5HTP and Tyrosine every night along with L-Theanine and some GABA lozenges too. These 4 really synergize quite well together. I've noticed much better sleep and a lot less depression and anxiety during the day as well.
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
Awesome. Glad to hear that. I usually recommend tyrosine in the morning to pick up mood and then 5htp at night for relaxation and sleep
@MdShahin-nm7xw
@MdShahin-nm7xw 4 жыл бұрын
How many mg do you have taken sister? Pls update how it works for you
@brucebanner912
@brucebanner912 3 жыл бұрын
hello. How it works for you? How many mg of these drugs are you taking?
@brucebanner912
@brucebanner912 3 жыл бұрын
hey
@husamalbayati4433
@husamalbayati4433 Жыл бұрын
I take L.Theanin 200 mg (one capsule) with 5HTP 100 mg (two capsules) every day.
@Ahmad-yi8yl
@Ahmad-yi8yl 4 жыл бұрын
Thank you Dr. Janelle Sinclair!
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
My pleasure 👍
@madlenj.4644
@madlenj.4644 Ай бұрын
@@DrJanelleSinclair i feel depressed, have 0 motivation and everyting feels exhausting. But if i take 5HTp i feel calm but not wanting to do anything (its exactly the same state when you lay tired in bed and will fall asleep in some minutes). If i take L-tyrosine i either feel nothing or i feel fatigued. Whys that and what could i do or take?
@DrJanelleSinclair
@DrJanelleSinclair Ай бұрын
@@madlenj.4644 I just you look into other causes of depression other than serotonin and dopamine imbalances. I have a free online course that goes through diet, gut health and nutritional deficiencies. Definitely get all the blood tests recommended and rule out deficiencies. So many deficiencies can cause depression and fatigue. www.drjanellesinclair.com/ecourse
@mr.anindyabanerjee9905
@mr.anindyabanerjee9905 3 жыл бұрын
Very well explained 👍
@fabianogiglio5170
@fabianogiglio5170 3 жыл бұрын
Great information. Thank you doc. I love your accent by the way :)
@JD-wx3pk
@JD-wx3pk Ай бұрын
Great video and invaluable knowledge. Thankyou
@Thomas-pq4ys
@Thomas-pq4ys 8 ай бұрын
I just saw a video on being serotonin dominant... and believe I fit the bill. I also suspect, I'm dopamine deficient... I'm ADHD. Adderall was overkill, and quickly became inefficient, destructive to the clarity of thinking. At one time I took an SSRI for depression, and it made everything worse... extremely so... intense adhedonia, no joy, even at things that gave me joy in the past. In my youth, drugs and alcohol did a wonderful thing to lift my mood, increase motivation, and even helping this ADHD guy focus, intensely. I'd rather not get my dopamine from drugs and alcohol.... I need to find a less harmful and healthy way to do so. I will give L-Tyrosine a shot. Thank you.
@gotzz84
@gotzz84 Ай бұрын
So how did it go with l-tyrosine?
@intermilan6202
@intermilan6202 3 жыл бұрын
Excellent video - Thanks!
@stevendriskell
@stevendriskell 2 жыл бұрын
Thank you. I needed to know how to balance them properly.
@ifonly2675
@ifonly2675 4 жыл бұрын
As a dopamine deficient individual i supplement with L tyrosine or L phenylalanine. I only use small amounts of tryptophan from time time when i get sudden and unusual sugar cravings. This is the trigger that my serotonin levels are too low. However if i take 5 htp or tryptophan alone then my depression gets so much worse. It takes a lot of time and experimentation to know what works for you
@tashalodge1340
@tashalodge1340 2 жыл бұрын
5 htp was awful for me when I took it before. That was without l tyrosine. I've worried a little that I'd deplete my serotonin taking the l tyrosine alone... I guess I can do similar if i start to see symptoms of seratonin deficiency. It's interesting.
@mikeg.3480
@mikeg.3480 3 жыл бұрын
Great information! Thanks!
@neptronix
@neptronix 3 жыл бұрын
Great video, thank you!
@MrMusic-ob2jj
@MrMusic-ob2jj 3 жыл бұрын
Thank you very much. Great content 👍.
@VijayRobertmodlr
@VijayRobertmodlr 4 жыл бұрын
This is what i am looking for,Thank you very much....
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
My pleasure ♥️
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
@Wilfy Martinez the 10:1 ratio is just a starting guide. If you need more dopamine and feel better on higher levels of tyrosine then the ratio of 675:50 should be fine.
@saidelhindawidelgado93
@saidelhindawidelgado93 Жыл бұрын
Thank you for amazing info Dr. my question is simple, If the supplement is helping and you figure out your dose range, for how long is safe to continue taking it and also there are any sort of withdrawal symptoms after severing its use. Thank again for your support
@zixiswexi
@zixiswexi 2 жыл бұрын
Amazing video! Thank you. 🌸
@DrJanelleSinclair
@DrJanelleSinclair 2 жыл бұрын
Our pleasure
@mandelmon1
@mandelmon1 3 жыл бұрын
Thank you so much for this !
@whenhelfrozeover
@whenhelfrozeover Жыл бұрын
Excellent video💯
@paulflint6254
@paulflint6254 2 жыл бұрын
Thanks for the video, i definitely have serotonin deficiency. Anxiety and anhodenia
@behindyou3689
@behindyou3689 Жыл бұрын
Have you gotten any better in 8 months?
@paulflint6254
@paulflint6254 Жыл бұрын
@@behindyou3689 on new tablets so anxious less. Lamotrigine
@gambit3950
@gambit3950 3 жыл бұрын
I think I need both, thanks!
@wread1982
@wread1982 4 жыл бұрын
Great video thank you 🙏 😊
@ApolloBlueLIne
@ApolloBlueLIne 3 жыл бұрын
I had wonderful success for about 6 months with 5htp at around 150mg a day. I then started having numb hands, neurological issues and felt very unhappy. I believe it was depleting my dopamine levels as it is slowly improving. I am finding it very hard to balance these isolated nutrients. You can find them balanced in foods, almost like that was where we were intended to get them.
@tapatot541
@tapatot541 2 жыл бұрын
Do you take it with tyrosine ?!
@jorgeluisrodrigues1322
@jorgeluisrodrigues1322 2 жыл бұрын
It's worth a try.
@TheAlibabatree
@TheAlibabatree Жыл бұрын
5htp worked ridiculously well for me (like, unbelievable) for about 4 weeks, then i noticed some side effects, and stopped using it. Im about to order some Tyrosine now, and I’m gonna try it again (its been a few months) both together. I know these supplements are not supposed to be used indefinitely, but if i can get even 6 months to a year, that might make all the difference.
@HaradaVar
@HaradaVar 2 жыл бұрын
I'm sorry what is 1:10 ratio? I couldn't understand that part. Like the dosage of L Tyrosine should be 10x higher than 5 HTP? Can someone please clarify?
@bblack.orchidd
@bblack.orchidd 2 жыл бұрын
I've been taking 5 htp and it works wonders for me in terms of my mood but not my energy levels. I do struggle with very low fatigue and depression. I took my first dose of L-tyrosine yesterday and the migraine that followed is so bad that I can't take it again. I still have a migraine today
@LillyOfTheValley77
@LillyOfTheValley77 Жыл бұрын
How many mg of tyrosine did you take? I have heard of this side effect more than once sadly
@binathere2574
@binathere2574 Жыл бұрын
I have understood that when Tyrosine give a headache it usually means you already have adequate Tyrosine.
@jessicayms2135
@jessicayms2135 4 жыл бұрын
Thank u for a comprehensive video Dr Janelle, appreciate yr work😊 Currently i am taking Ashwagandha for anxiety and L-Glutamine for stomach lining. Is it ok to take them with 5-HTP and L-Tyrosine ?
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
No problem. Just take the tyrosine on an empty stomach.
@jessicayms2135
@jessicayms2135 4 жыл бұрын
@@DrJanelleSinclairThank u Dr Janelle.. I m taking 5-HTP with L- Tyrosine 3 days already as per dosage recommended in yr video.. I feel sleepy during the day.. Is it normal ?
@manchester8143
@manchester8143 Жыл бұрын
​@@jessicayms2135 yes thats normal
@MeeraRaju1111
@MeeraRaju1111 4 жыл бұрын
Thank you! This is a wonderful video.❤
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
Thank you so much. Did it answer all your questions?
@MeeraRaju1111
@MeeraRaju1111 4 жыл бұрын
@@DrJanelleSinclairMostly, yes. I recently discovered I have PMDD. I also have endometriosis and was diagnosed years ago with Bipolar disorder, which I personally think was Pmdd. I refuse to take prescription medication and have been searching for alternatives. Your videos have been extremely helpful to me. I got some chaste Berry & have been taking that during the day and the 5-HTP at night but I'm not sure about l-tyrosine. Thank you so much for all the hard work you put into these videos you have no idea how many people you are helping.❤❤❤🤗
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
@@MeeraRaju1111 my absolute pleasure ♥️. I'm so glad they have been helpful. Check out my videos on vitamin d and zinc too. I'm also going to be offering a paid online course in about a months time. So keep an eye out for it if that interests you.
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
@@MeeraRaju1111 you've made my night with your encouragement.
@MeeraRaju1111
@MeeraRaju1111 4 жыл бұрын
@@DrJanelleSinclair That would be wonderful!❤
@idiotheh
@idiotheh 3 жыл бұрын
I take both and it's been a miracle. I tried every variety of antidepressant for years and they never improved anything.
@케로로-중사
@케로로-중사 3 жыл бұрын
can you tell me more details review? :)
@csgotunibetprediciton4019
@csgotunibetprediciton4019 2 жыл бұрын
Hey, in what dosage you took them?
@dorislacej8717
@dorislacej8717 Жыл бұрын
In what dosages?
@manchester8143
@manchester8143 Жыл бұрын
Wow thats great
@joanneg665
@joanneg665 Жыл бұрын
Excellent ☀️ thank you 💛
@just_bee9482
@just_bee9482 2 жыл бұрын
my brain needs both asap. I am doing well staying off pmo for a few months already after three decades of abuse but my brain has lot of repair to do.
@bassemeskander414
@bassemeskander414 4 жыл бұрын
This doctor is smart as she is pretty... And she's very pretty! Thanks for this information
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
Thanks so much 🤣☺️
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
@Wilfy Martinez sorry I missed your question. Yes that ratio should be fine
@LoriBradshaw
@LoriBradshaw 4 жыл бұрын
I definitely lean towards a Dopamine deficiency Depression Fatigue Inability to feel pleasure Poor Motivation Poor Concentration
@death.for.breakfast
@death.for.breakfast 4 жыл бұрын
Same
@IISuperw
@IISuperw 3 жыл бұрын
Same here. No.motivation in life to do anything Even if i think about doing my job, that would trigger my anxiety. Any idea how to feel motivated and anxiety free ?
@twoibrad3688
@twoibrad3688 3 жыл бұрын
@Anmo yes, take 1g of Omega 3 EPA daily, also highly bioavailable Vitamin D3 (best with K2 MK7) and magnesium glycinate. I've tried and researched a lot and these are my big three. Exercise is hella important too though. This 4 things will make you feel satisfied nearly all day and night long
@manchester8143
@manchester8143 Жыл бұрын
​@@IISuperw same here
@IISuperw
@IISuperw Жыл бұрын
@@twoibrad3688 true. I tried vit D. It did make a difference. But takes time. It took me a year to feel better
@markspurgeon5646
@markspurgeon5646 4 жыл бұрын
AM: Ashwagandha + ZMA + L-Tyrosine PM: 5-htp + CBD
@ashleywyatt7114
@ashleywyatt7114 4 жыл бұрын
What is zma? And what brand of cbd would you recommend? Also what brand ashwagandha?
@daniellefudgell6359
@daniellefudgell6359 4 жыл бұрын
For depression what dose do you recommend for each and when do you recommend to take them
@jbuddyman
@jbuddyman Жыл бұрын
Thanks for the info. I've been supplementing with both l tyrosine and 5htp for a few months. I must say, it has to be the combo as there is no way one supplement would do this. But it really does make sense. I have learned about catacholamines and l tyrosine will convert to all 3 catacholamines ( dopamine, epinephrine and norepinephrine) by addd. And 5 htp to l tryptophan or serotonin. I may suggest adding l glutamine to keep glutamate ratios up with the rest of the neurotransmitters and b vitamins which are good for the acetylcholine neurotransmitter. Long story short, stacking these supplements at the right ratio will give ultimate balance
@jbuddyman
@jbuddyman Жыл бұрын
Oh and don't forget l theanine for GABA. Taking gaba on it's own is not useful since it can't cross the blood brain barrier. In short 200mg 5 htp ( extended release recommended if you can find it ) 200mg l theanine 1g l tyrosine 1000mg or more of all b vitamins 500mg l glutamine This stack I rely for neurotransmitter balance and I've never had a problem taking this everyday but that's me.
@rayanemartins544
@rayanemartins544 9 ай бұрын
How much you take 5htp and tyrosine?
@jaclynrawls8573
@jaclynrawls8573 4 жыл бұрын
Thanks so much for this video! Question: why does everywhere I look on the internet say to take L-Tyrosine for up to 3 months. Does this have something to do with how long it was studied? Can I take it longer?
@Soaring_Seajay
@Soaring_Seajay 4 жыл бұрын
Jaclyn Rawls Wondering as well.
@zianawind2970
@zianawind2970 4 жыл бұрын
I just get that is meant to be cycled to allow the body to readjust it’s chemical flows, like stop 2 3 weeks see how you doing before restarting. I don’t have the exact science for that but the body does better letting it have a rest cycle from the feedback it’s required from taking the supplement
@sharadeniese8703
@sharadeniese8703 4 жыл бұрын
Thanks Dr. Janelle I managed to come out of antidepressant with your help. Its been a week without Cymbalta. I have been taking 5HTP 50mg 3 times a day but i still feel confused cannot remember things much so i will add tyrosine from tomorrow onwards. I also have been taking L theanine 500mg twice a day morning and evening. I wonder if its necessary to have them both. Appreciate your help dr. i am a single mum and have struggled 17 yrs with antidepressants i want to look after my daughter who is 16 now. May god bless you.
@keelyleilani1326
@keelyleilani1326 4 жыл бұрын
I had the same issue with the 5htp and I started taking only one dose right before bed along with Tyrosine, L-Theanine, and GABA.
@ozguratakul3066
@ozguratakul3066 4 жыл бұрын
Hi, what's your current status?are you off the antidepressant? I hope you made it. :))
@abdul-rahmanwashington2479
@abdul-rahmanwashington2479 4 жыл бұрын
8:25 too cool. I am subscribing.
@memati7199
@memati7199 2 жыл бұрын
Dr Sinclair 🖐🏻🤓 can i combine both L-Tyrosine and DHEA , for fatigue and mood ? Wish you a lovely day and thank you for your efforts 🌷
@arichardson5903
@arichardson5903 3 жыл бұрын
Dr. Sinclair, What do you think about Tryptophan used with 5-http?
@TheWoundedWarrior
@TheWoundedWarrior 4 жыл бұрын
I prefer to go one step above and take tryptophan personally. Study symptoms individually and put it in one camp or the other. If you are serotonin deficient, then take either tryptophan or 5-htp. If you are dopamine deficient, take tyrosine. Don't take one JUST because you are taking the other. Treatment must be symptom based. That being said, one will brake and accelerate the other. You are aiming for a balance but you also need to be taking BOTH amino acids in through your diet anyway or in supplement form. You can't put one into the body and starve it of the other one. Keep in mind, tyrosine+iodine+selenium is needed for healthy thyroid function. Dopamine deficiency can make you tired but so can an underactive thyroid due to lack of tyrosine/iodine. If you are switched on enough, you can actually tell what chemical your brain is seeking. Also, beware of sugar foods. These provide a quick hit of brain chemicals so if you are constantly snacking on them. It can be a sign that you are completely amino acid starved. Throw that in with a bad thyroid and it's a recipe for huge weight gain. Don't forget, tyrosine in particular can affect heart health and blood pressure as well. If in doubt, take them individually, the uptake through your body might be so rapid due to being starved of an amino acid for so long you can experience all sorts of symptoms. In cases like these, take 10-20% of the recommended dose. If the effects then work out to be beneficial to you then just take as required. It's like swimming. You'll soon learn how to ride the waves.
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
Thanks Russell for your input. One should definitely concentrate on improving your diet first before taking supplements
@redrock1963
@redrock1963 4 жыл бұрын
The MOOD CURE by Julia Ross, M.A Dovetails with all that the Doc is saying here.
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
Good to hear that. Thanks.
@icyman2020
@icyman2020 4 жыл бұрын
Thank u very much doctor u r the best 👍
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
My pleasure
@vasiliosg8322
@vasiliosg8322 4 жыл бұрын
Thanks for the video! Could you maybe do a video about the effect that fructose absorption has on serotonin, zinc and folic acid levels? I was diagnosed with this a couple days ago and my depression, fatigue and gut problems make so much more sense now
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
Thanks for the video idea. How has this helped you?
@vasiliosg8322
@vasiliosg8322 4 жыл бұрын
@@DrJanelleSinclair I tried 5 htp and tyrosine and it really improved my mood
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
@@vasiliosg8322 so glad to hear that! How long did it take to work?
@vasiliosg8322
@vasiliosg8322 4 жыл бұрын
A couple of weeks I think. It must be either this also the vitamin b complex I also started taking
@Lluiana
@Lluiana 3 жыл бұрын
Very informative
@PankajSingh-br8xw
@PankajSingh-br8xw Жыл бұрын
Great info
@danaiboubari930
@danaiboubari930 3 жыл бұрын
Hello Dr. Janelle :) I wanted to ask about whether supplementing LTyrosine or LDopa is the same. Thank you in advance.
@iiii8467
@iiii8467 2 жыл бұрын
I wonder if the treatment options for dopamine depletion, levodopa will be more efficient than tyrosine, because tyrosine also needs to be converted to levodopa, while the common enzyme is AADC, AADC converts 5htp and levodopa to serotonin and dopamine
@eatpierightnow
@eatpierightnow 4 жыл бұрын
I want to quit my antidepressant lexapro and start useing amino acids I also take welbutrin but dont plan on quitting. Can I take both 5htp and l tyrosine with wellbutrin? Also if I start useing 5htp can I stop the lexapro faster? I'm down from 20 to 10 mg but want to just stop at this point
@rafaelhorna868
@rafaelhorna868 3 жыл бұрын
You got this! I was on lexapro for 3 years and got of just tapering, 20, 10, 7.5, 5, 2.5... each for 2 weeks. I personally feel a lot better of it and am taking Probiotics for gut health, Ltyrosine and i have cut out my caffeine consumption which tremendously helped my anxiety.
@YourNay
@YourNay 3 жыл бұрын
I have ALL of these symptoms due to high levels of anxiety and stress but serotonin levels are great where my dopamine is
@ozguratakul3066
@ozguratakul3066 4 жыл бұрын
thanks for the great information
@brucebanner912
@brucebanner912 3 жыл бұрын
benim ingilizce yetmiyor da tam olarak ne diyor videoda acaba l tyrosine ve 5 htp ile ilgili? yardımcı olursan sevinirim.
@ozguratakul3066
@ozguratakul3066 3 жыл бұрын
@@brucebanner912 www.fitekran.com/5-htp-nedir-neden-ve-nasil-kullanilir/ BURAYA BAKARSANIZ AYNI BİLGİLERİ BULURSUNUZ
@brucebanner912
@brucebanner912 3 жыл бұрын
@@ozguratakul3066 hocam aldım tirozin ve 5-htp. 5-htp işe yarıyor gibi de tirozin için hiçbir şey diyemeyecem. günde 500mg aç karna alıyorum solgarın l-tirozinini. acaba üründe mi sıkıntı var yoksa aldığım dozda mı hiç bilemiyorum. senin görüşün nedir?
@computeck9984
@computeck9984 2 жыл бұрын
Thank you so much for sharing your knowledge ! My therapist recommended GABA to treat my anxiety and depression, what's your thoughts on GABA ?
@matthewirvin6505
@matthewirvin6505 2 жыл бұрын
they say it helps calm your gut mood than your brain because it doesn't cross the BBB
@mariameere5807
@mariameere5807 3 жыл бұрын
Thank you honey!! Your advice has since my life practically! I just want to know does one interact with the other one if you take them at the same time and cancel the other one out? I read that you shouldn’t take amino acids altogether because L tyrosine and L Phenaline sorry I can’t spell the second time, cancel out the rest! It was in a book by Patrick Holford and he recommends taking five HTP when you want to chill out and taking L tyrosine when you want energy! He says don’t take them together because they will cancel each other out whether he does say there is a need to take one when you take the other one for the reasons you have mentioned in your fabulous video! I want your take on this please?! Thank you for informing everybody and please do not listen to Ungrateful Spiritually unconscious people! LOL!
@MrsPaulaTorres
@MrsPaulaTorres 3 жыл бұрын
Mmm that’s nice to learn as I’ve taken L-tryptophan to stabilise heart rate already, now picked l-tyrosine now during 3rd trimester of pregnancy per #medicalmedium thyroid healing protocol advice - box of supplements, to keep up with hashimotos symptoms & fight off the EBV, amazing how I had no idea of the anti-depression thing but I do feel I am sleeping better, catching the first sleep wave earlier, had a nice nap today in the afternoon too, yass 🐍 Also I take 5MTHP sounds as it’s something else as mine is for proper gene development of the baby 😅 nott anti-depression L-tyrosine has broader applications than “anti depression” depression is a symptom to begin with Anyway, good stuff
@FrozenKingdom34
@FrozenKingdom34 4 жыл бұрын
Got all shaky and anxious after taking 5-htp long term. Had no idea.
@DJRenee
@DJRenee 3 жыл бұрын
How much were taking?
@dinta8692
@dinta8692 2 жыл бұрын
Thank you Doctor! great work! tell me if these 2 drugs can be taken by a person suffering from hypertension and he has high cholesterol, he drinks satins. Or is there an alternative to l-tyrrosine if it raises blood pressure? maybe add a motherwort?
@manchester8143
@manchester8143 Жыл бұрын
Yes you can
@nk5686
@nk5686 4 жыл бұрын
Thank you doctor for the video i have a question i recently stop my ssri paroxetine, and its been 7 months off medication now, but i am more anxious and depressed than usual so there is a myth that ssri increase serotonin and decrease dopamine, can i take l tyrosine to boost my dopamine, i m thinking that my dopamine getted lower after ssri.
@DJRenee
@DJRenee 3 жыл бұрын
Probably did
@rosy21284
@rosy21284 3 жыл бұрын
What are some good brands that are any one with good results can possibly recommend. Thanks
@winterpaws01
@winterpaws01 Жыл бұрын
How would these two play togethor with SAM-e? Is there any reasons not to use all 3 (SAM-e for liver issues). Thank you, fantastic video
@freeloop7738
@freeloop7738 2 жыл бұрын
great video
@marnykhalil8845
@marnykhalil8845 4 жыл бұрын
Thank you for this very informative video I have one question You mentioned not to take l-tyrosine if a person is diagnosed with bipolar disorder Can you elaborate on the reasons why not? And what to do in case of a bipolar disorder diagnosis in terms of taking 5htp and l-tyrosine supplements? Thank you
@DrJanelleSinclair
@DrJanelleSinclair 4 жыл бұрын
Hi Marny. One of the possible causes of bipolar disorder is high dopamine levels. Tyrosine increases dopamine, so you should not take it if you have bipolar. I would look into zinc deficiency, vitamin d deficiency, progesterone deficiency and mthfr genetic weaknesses. I've got videos on all of those imbalances and you can treat the deficiency and this may help bipolar.
@nick2128
@nick2128 3 жыл бұрын
@Wilfy Martinez how many times are you going to ask that
@Sahibamokha6303
@Sahibamokha6303 3 жыл бұрын
Can you take 5HTP with Ashwagandha or Gingko Biloba? Please let me know!
@ArrivalQ81
@ArrivalQ81 2 жыл бұрын
I have been diagnosed with anxiety by my therapist due to symptoms regarding to sugar cravings, porn addiction and premature premature ejaculation, however I’m looking for natural ways to overcome these symptoms, so I’m wondering what is the perfect dosage of 5htp for me (of course beside healthy lifestyle habits) And is it necessary to consider l-tyrosine if I’m willing to be on 5htp for long term? Thanks a lot🙏
@Pellican516
@Pellican516 7 ай бұрын
seems as though your being over stimulated with the porn too much actions coming through your eye gate. sugar cravings use a natural sugar, agave, cane sugar...you can over come it just slowwwww down. you are stronger than you think.
@jefffisher1045
@jefffisher1045 3 жыл бұрын
What kind of doctor should I see to check my levels that you talk about here and give advice on these supplements.
@giovannicampos5838
@giovannicampos5838 3 жыл бұрын
Dr if the patient has anxiety and fatigue but very mild symptoms, only can take the supplements when is at home is ok to have only 1 dose of each supplement. Tyrosine 500 mg before breakfast, and 5 http 100 mg night time? thanks amazing explanations!
@youmuqututube4248
@youmuqututube4248 Жыл бұрын
Thank you ❤️❤️❤️
@PGNorthernBC
@PGNorthernBC Жыл бұрын
Hi Dr, is taking 5HTP for a long period connected with osteoporosis? I’m reading mixed write ups and not sure if I should take it.
@kareemahmed7028
@kareemahmed7028 Жыл бұрын
thank you dr.
@FABRICIOSOUZAHB315
@FABRICIOSOUZAHB315 4 жыл бұрын
Great Job!
@HerbertCruz27
@HerbertCruz27 4 жыл бұрын
Thank you for this info. I’m taking 200 mg a day , taking 100mg “olly” GABA and also Adrenal and cortisol health? Is that a bad combo ? Not trying to take an anti depression meds.
@thomashudson6676
@thomashudson6676 4 жыл бұрын
Way top much
@Viv8ldi
@Viv8ldi 3 жыл бұрын
Can I take tyrosine while being on thyroid medication l-thyroxine 150mcg (at least thats the name here in Germany) for hypothyroitism? It was recommended to me for my thyroid and for my problem with always being tired, but when I took it I felt like negativly on fire and couldnt sleep the whole night. Or maybe it was an interaction with fluoxetine I was on back than 20mg?
@rameshbankala3030
@rameshbankala3030 2 жыл бұрын
Thank u mam love from INDIA🇮🇳
@candacequintero876
@candacequintero876 3 жыл бұрын
Is taking 5 htp and L tyrosine long term bad? I have a heart murmur. I don’t want to get on antidepressants because they’re horrible, and I recently started taking them together but I’m scared if I got off of them all of a sudden would I have bad side effects?? Also, does taking them long term do anything bad to the body? Also, can I get serotonin syndrome from taking 5htp & eating foods like salmon 🍣? I’m just overthinking it but I’m terrified of serotonin syndrome. Thank you in advance
@pauldurus4783
@pauldurus4783 2 жыл бұрын
Thank you for all this good info. Does anyone knows where to buy this products from in order to have a good quality. The market is full of brands and makes it difficult to pick the right one. Thank you.
@Saudi.Arabia.
@Saudi.Arabia. 4 жыл бұрын
Doctor please answer ... can i take 5HTP while I’m on Risperdal consta 25 mg ??
@shardaycota9164
@shardaycota9164 4 жыл бұрын
I'm only taking it for pms.. only when I pms . 5 days out of the month..before my menstrual cycle...so as needed... I only take 50mg. Works great! But should I take l tyrosine as well? If so, how much? Can I take both at lunch? Or both I'm the morning
@CambodianAmerican
@CambodianAmerican 2 жыл бұрын
How about taking l-tyrosine and l-tryptophan together on the same day and how much dosage each?
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