What Science ACTUALLY Says About Glucosamine & Chondroitin

Рет қаралды 365,844

Жыл бұрын

I review Glucosamine Sulfate and Chondroitin for Joint Pain & Arthritis.
pubmed.ncbi.nlm.nih.gov/35924...
pubmed.ncbi.nlm.nih.gov/35024...
bjsm.bmj.com/content/52/3/167...
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Пікірлер: 585

@garryjistel280 10 ай бұрын

I have been taking glucosamine and condroitin for 40 years. It has kept me on my feet and avoid knee replacement. I am not going to stop it now. I was diagnosed with osteoarthritis in my mid 20's. I am now 68.

@tamilkalakkalkitchen623 9 ай бұрын

Is it true ?? Are you able to manage this situation for 40 years...

@phlotographer 8 ай бұрын

I have been using 1500 MG Glucosamine Sulfate from Costco for about half the time of your usage. It was recommended by a friend and I was told to use it for at least 2 weeks. Even prior to that the severe pain I had with my R achiles tendon was eliminated. However, when stopping usage, the pain immediately returned and so I have never stopped using the product and likely never will but I might do another test to see if the issue has totally disappeared over the years.

@tresahines9862 8 ай бұрын

Wow thank you for that information, I don't want surgery

@leisurely6711 7 ай бұрын

Have you gotten recent mri it ct scans? I wonder if there was any improvement

@HepCatJack 7 ай бұрын

Some supplements also include Elk Velvet Antler (Cervus Elaphus Canadensis) and Devil's claw. Others have white willow bark, Boswellia serrata extract, Boswellic acid, Lumanite, Selenium, Maganese, Pantothenic acid and collagen.

@artwise1415 5 ай бұрын

I'm 73 years old. I don't have arthritis. I run. I'm physically active. I do take Glucosamine and chondroitin. My study is my aging body. When I don't take it for a month or two my knees and hips hurt and keep me from running and even from long walks. When I get back on the glucosamine and chondroitin, after a few weeks the pain diminishes to no pain at all. I can sprint, top speed, the joy of flying on my feet. I feel good in my body. It feels great to feel good. That's my personal research. Onward.

@richardf911 4 ай бұрын

I've heard similar stories from a number of runners. Glucosamine works. Chondroitin is unnecessary.

@heleneikerenkotter2950 3 ай бұрын

I would never take this supplement as a solo. They work better in combination. The better supplements come in combination and made with Glucosamine sulfate and Chondroitin sulfate and not Glucosamine and Chondroitin hydrochloride . These are not drugs and represent the vital structure of joint tissue itself. It also promotes resiliency of other flexible tissue such as skin , arteries ,veins and heart valves. This is information found on the container of my supplement and the maker does not mess with supplements that are useless. He does years of studies before he makes the product. My husband and I both take and notice a difference when we stop. If you are allergic to the shells of shellfish ( shrimp, crab and crawfish ) do not take. Look at most studies that discourage supplements and encourage OTC or steroid injection with jaundiced eye. You have to take this supplement for a period of time to notice a difference. This is not a quick fix. This is not instant pain relief and temporary . It takes time to ruin joints and it takes time for them to heal and repair.

@lynamor2959 3 ай бұрын

Amen! 🙌💯💪

@a.scotth.9955 2 ай бұрын

My mother took it and eventually was pain free. I have arthritis in my thumb joint that joins my rest in one hand and in the middle of my hand to mt wtist in the other hand. I have arthritic damaged several fingers. Wonder if it would work for these locations. Don't see why not.

@sailingaeolus 2 ай бұрын

Same for me but I'm mid 50s.

@digital.mente. Жыл бұрын

My own totally non scientific study with my own knees is that the supplement I take with glucosamine, chondroitin, collagen, msm, hyaluronic acid and a few vitamins means no pain in my knees. When I don't take it for a couple of days the pain comes back. You have to try different brands to see which works for you.

@JeffreyPengMD Жыл бұрын

Thanks for sharing your experiences!

@scotchbarrel4429 Жыл бұрын

I just checked my glucosamine supplement, and bloody hell, there's no chondroitin in it 😂 Great vid, had to change the filter to recent to pickup this new update, otherwise first results are vids from 2 - 6yrs ago, and all consensus on the skeptical side, which didn't feel to good, considering I'm taking this stuff, but my man has reassured me that I'm on the right track, just gotta find one that includes chondroitin.

@malihahaque3710 Жыл бұрын

Any side effects ?

@digital.mente. Жыл бұрын

@@malihahaque3710 For me none that I have noticed.

@holycrapfreakinsweet Жыл бұрын

is there any way for us to eventually overcome the dependency with supplements? like sure, I'd want to take them on for a certain amount of time, but not ALL OF THE TIME. that to me is just not helping.

@phillipoleary2532 6 ай бұрын

Glucosamine alone worked for me. At age fifty was told both knees needed replacement and I had severe pain. Glucosamine was recommended and now at age eighty nearing eighty one am still running upstairs. No pain, no grating, no locking for thirty years. Only addition was MSM at age seventy.

@rit20095 5 ай бұрын

Great to hear that. I have been diagnosed with osteoarthritis of knee

@matterafact Ай бұрын

What brand my friend

@phillipoleary2532 Ай бұрын

No particular brand just Glucosamine 1000mg twice a day, told just need once a day, but if it works why change it? If you are not vegetarian can get it with chondroitin, which is I’m told especially good.

@tarared7668 22 күн бұрын

I started taking NOW glucosamine only 3 days ago for my shoulder bursitis. How long for the medicine to take effect on my body?

@helendy2743 19 күн бұрын

Would you mind what brand you're taking...many thanks God bless.

@martinpolach1330 Жыл бұрын

I will be 77 this summer .. I still xc and down hill ski….I ride a mt bike ….I have been taking glucosamine and chondroitin for more than 20 yrs … I’m VERY fortunate that I don’t have joint issues ..!! Studies or no…but it works for me …

@somerset6646 10 ай бұрын

I was skeptical, but I recently started taking glucosamine, chondroitin, MSM, and it has helped my knee pain and overall aches. I take the triple strength.

@Pellican516 5 ай бұрын

What is the triple strength

@isaacelone3699 3 ай бұрын

@@Pellican516 probably 3 times more than the usual dosage sold on the market?

@nexxterra 10 ай бұрын

I love how the study says "in the short term" I have never been under the impression that these were beneficial unless taken for a while...

@heleneikerenkotter2950 2 ай бұрын

This is not a supplement that works short term. It takes time for it to work to feel a difference. It is a long term supplement. It took a long time to develop worn painful joints and it takes time for Glucosamine, Chondroitin and MSM to help in the healing process. We have become a society of instant gratification. The body heals but not in an instant. An ounce of preventation is worth a pound of cure . Look at medical studies with a jaundiced eye. Who is sponsoring the study?

@phillipoleary2532 Ай бұрын

Yes! I were late in ordering my supply once, and in just over a week felt the ache coming back.

@islandbirdw 6 ай бұрын

Your presentation was clear concise and easy to understand. As a wellness nurse I firmly believe knowledge is the key to helping people engage in pursuing healthy sustainable habits over a lifetime. People generally will be willing to make positive lifestyle changes if they can see benefits early in the course of any potential illness.

@67daltonknox 7 ай бұрын

In my late 40s I had knee pain hiking and skiing. I even took up scuba so I would have a sport if my knees got worse. I also started G&C daily. It took a couple of years, but I was able to stop using neoprene compression on my knees. Now 76, my knees are fine and I'm still hiking and skiing, yes and taking G&C.

@BillyG869 6 ай бұрын

In 1993 my wife and got rear ended by a truck on the freeway. After that my neck was trashed, so painful it literally limited me to muscle relanta and pain pills. Months after doctors, orthopedic surgeons and eventually chiropractors. Then I started taking a very heavy does of glucosamine/chondroitin. It took a few months to take hold, but eventually I believe my cartilage became more functional and possibly repaired itself. That is a fact and it made me functional once again. I’m now 77 work hard and take little meds. If I were to sustain another damaged joint, I would immediately turn to this supplement once again. It takes a steady intake of a sizable dose, and it takes several months to recognize its effects. See for yourself…

@team2mom805 Ай бұрын

Which brand?

@Southprong59 6 ай бұрын

I have a bad case of osteoarthritis in my knee and took Glucosamine & Chondroitin pills for approximately 30 years and it helped somewhat. Then I switched to a liquid Glucosamine & Chondroitin approximately 18 years ago and it made a big difference. I experimented a couple of times by stopping my intake of Glucosamine & Chondroitin for 3-4 days and my pain increased. Obviously, you body absorbs liquids more readily than tablet forms; if you use Glucosamine & Chondroitin, I highly recommend trying the liquid form.

@theresahenry4936 5 ай бұрын

😢

@Pellican516 5 ай бұрын

What brand?

@Southprong59 5 ай бұрын

@@Pellican516 Nature's Way Joint Movement Glucosamine, Extra Strength - each serving contains 2000mg Glucosamine, 1200 mg Condroitin, msm, and vitamin D3. I purchased mine online through Vitacost. I took 3-3.5 teaspoons every day. You may want to start out with a little heavier daily dose for the first week to get it into your system and back of to 3 full teaspoons a day. I also take psyllium husk every day and mixed the liquid Glucosamine and water with my powdered psyllium husk. It doesn't taste bad; you could take it by itself or mixed with water or juice.

@RobertBee-fs8hv 2 ай бұрын

Never heard of liquid form

@Magstar757 Ай бұрын

How's it taste? Lol

@MrLeedebt 10 ай бұрын

For me, glucosamine was a miracle. But probably not for everyone. I started a job delivering meat in my 50's. I would jump off the back of the truck, trying to give the impression I was young again. After a few months, my hand and knee joints were extremely stiff and painful in the morning when I woke up. I started taking glucosamine and it brought immediate relief. Because I had worked these joints for only a few months, maybe it would be different for say a carpet layer or bricklayer, who may have done it all their lives. I kept taking them, even after leaving the job after 10 months. After three years I changed brands and it seemed to produce blood thinning and low blood pressure, so I ceased taking the glucosamine. Amazingly, I felt as good as I did prior to doing the job.

@joecook8352 7 ай бұрын

In my early thirties my elbows and knees would get horribly stiff and painful, I saw a 60 minutes show about msm, glucosamine and chondroitin and there were several older people talking about there experience with it, this was in the late eighties. I started taking it and it helped tremendously. I’ve taken them ever since and I’m 64 now. It worked for me. I started taking a prescription nsaid for arthritis several years ago in addition to the supplements because as I got older I got stiffer and it hasn’t helped near as much as when I first took the supplements

@erdemakgus4339 Ай бұрын

@joecook8352 I would like to get your opinion on the subject of GLUCOSamine. If you have an Instagram account, is it possible to write and share it here?

@mjanebautista9477 8 ай бұрын

Dr.Peng, thank you so much to your such a good information...

@00708046 6 ай бұрын

My experience taking Condroitin and glucosamine (g & c)together took time (several months ) but performed 3 repairs for me . 1/ I had a tear in my miniscus (knee) causing clicking and locking up with pain . 2/ My big toe was locking up and bending my foot in normal or quick walking was very painful . 3/ I tore a tendon in my little finger knuckle . By taking g & c 2 times per day for 4 months my toe suddenly made a loud click . I exercised it back an forth further clicking . I was able to walk and run again without restriction and pain . My knee stopped locking up and clicking after 6 months . I stopped taking my 2 doses and my toe locked up again after 2 months so I took g & c again and it disappeared in days . I would take g & c for 2 days whenever my toe would lock up . My knee remained healthy for nearly 11 years when after kneeling on a hard floor for 5 minutes doing repairs I acquired a new clicking not miniscus but more like a tendon that was sliding out of its normal place and rubbing badly . Im working on that with g & c and limiting the incorrect sliding by using elastic bandage when exercising now . I also had the same issue in my little finger knuckle . I would bend it but could not straighten it . I wrapped it to keep the tendon from sliding to the side of the knuckle and took g&c and in 2 months regained normal function . Glucosamine with Chondroitin has helped me fix tendon /ligament damage , arthitic joint lock (big toe) and repaired a torn miniscus in my knee so far . I would say that it has really helped make repairs in my body . After its already in my system , I only take it when joint damage occurs for brief periods . It seems to work for a few months after . I feel that it is helping the damage to reattach itself and mend back to its normal .

@ishitasolanki2422 5 ай бұрын

Thank you for sharing

@74747Kyle Ай бұрын

what was your dosage? same or more than recommended in this video?

@voxpopuli348 6 ай бұрын

I am 66. I started taking G & C in the 90s when I was still doing ballet. I kept taking it. I still do yoga, hiking, weight training, biking. I plant to keep taking it to stay off meds and nsaids. I also take turmuric and hyaloronic acid for my joints and ligaments.

@garygauthier1551 6 ай бұрын

I also have been taking glucosamine and chondroitin with MSM since 1998 ! At that time I was suffering with pain and stiffness in my right hip, my family doctor ordered a X-ray and found that I had moderate to severe joint degenaration in my hip. He suggested that I could try glucosamine and chondroitin with MSM. I also would see Chiropractors for neck & hip adjustments. After about 3 weeks I could feel my mobility had improved as well much less pain . Not only did I get improvement in my hip but also my neck issues disappeared. Just to mention that Veterinarians also prescribe glucosamine and chondroitin to horses & dogs that have mobility problems where noticeable improvement is seen ! One more thing that I think needs to be said is that glucosamine and chondroitin won't work if your joint is bone to bone.

@annpringle8219 Жыл бұрын

All your videos are great! Also glucosamine works for me and my knee pain.

@venenareligioest410 7 ай бұрын

I remember reading an academic paper which broadly said that daily Glucosamine with chondrites was as effective as ibuprofen at releasing pain. With the added benefit that the analgesic effects did not reduce over time, as Ibuprofen does.

@MyNigellus Жыл бұрын

Thank you very much for tackling this topic. Very useful for an average everyday user

@JeffreyPengMD Жыл бұрын

Thanks for commenting!

@armerwillenbring4732 11 ай бұрын

Several years ago my left knee hurt so much I couldn't go up stairs. I saw a knee surgeon who said nothing can be done and I should schedule knee replacement. I asked to have a PT appointment. He said 90% of my knee pain would go away in 3 months if I did the ankle and hip exercises he recommended. I did and my knees are still pain free. I use Glucosamine and MSM just for insurance. I regularly do the ankle and hip exercises. My hips and ankles were extremely weak before doing the exercises. Bottom line, define the problem before scheduling treatment.

@jondowling720 7 ай бұрын

Be very interested to know exactly which exercises you were prescribed if you don’t mind. Thank you

@debritukidane8163 5 ай бұрын

😅

@pohlianquek2580 Ай бұрын

Any video link on the exercises? Can pls share? Tq

@christianclavel216 20 күн бұрын

Can you describe those ankle and hip exercises, please?

@CorvetteLife 2 ай бұрын

Everytime I stop taking glucosamine my knees hurt

@etsout 2 ай бұрын

They've helped my pain greatly.

@marilynjackson5752 6 ай бұрын

Thank you so much. I'm starting this today.

$@fractalizedspiritz$

@fractalizedspiritz 29 күн бұрын

Dr. Peng is absolute BEST 🎉 😊

@paulmaglio9254 Жыл бұрын

I take Amlodipine. That and my Don Joy unloader brace are total game changers for me.

@edwinthomas618 3 ай бұрын

It works for me as i had Hip Flexor pain. Thank God I found this miracle 😊

@triston5540 8 ай бұрын

Great video! I have psoriatic arthritis. I’m on a biologic. I also have developed chondromalacia patella. These supplements I assume are tested by themselves not with any added rehab exercises. My hypothesis is that combination of these with a proper workout plan designed to promote cartilage health might increase the rapidity and total gains seen in the injury.

@nealdickman5897 Ай бұрын

I agree. More studies need to be done about whether Glucosomine and Chondrotin is an effective sopplement to help hip, knee and other joint pain.

@michaelcale272 9 ай бұрын

It appears that this helps my wife greatly in regard to joint pain

@michaelh2797 Жыл бұрын

I agree with digital.mente. I've been taking Osteo Bi Flex for years. I've tried other brands when the store was out, but they didn't work as well. And if I run out, I can really feel it!

@JeffreyPengMD Жыл бұрын

Glad you found something that works for you!

@stevec8861 7 ай бұрын

Been taking Osteo Bi-Flex or generic triple strength equivalent for decades after osteoarthritis started in my hands in early 40s. Works great. However, I take 2-3X what label says (2 pills per meal vs. label dose of 2 pills per day with food), which is also 2-3X dose that doc here suggested near end of video. At lower dose, my joint pain quickly returns.

@tabathv1 3 ай бұрын

I have been taking them since my thirty’s to avoid having problems as my mother suffered from arthritis. I’m nearly 60 and gave to say my joints are in good condition for my age

@josephabdilla1383 Жыл бұрын

Thanks Very helpful

@bestsk8eva Жыл бұрын

Thank you Dr Peng for the info 🙏I'm your new subbed!!!!

@JeffreyPengMD Жыл бұрын

Welcome! Thanks for commenting!

@SS-jb8wj 6 ай бұрын

I knew I had arthritis in my knees and the specialist said I would need a knee replacement down the track. In February 23 I started weight lift training. I now have no pain in my knees and I have ditched the cane. The replacement diagnosis 10 years ago. The weight lifting has built up the muscles around the knees supports the knees.

@fatoomgierdien110 11 ай бұрын

Thanks for a great video. 👌🙏🤲♥️

@serenity8475 Жыл бұрын

Thank you for your research and all you do to inform us. YOU ROCK! 🙌 BTW: I have been taking it for awhile now and it is deff God sent🙏🙏🙏

@JeffreyPengMD Жыл бұрын

Thanks for commenting!

@mikelanglow-bi2sv 9 ай бұрын

THANKYOU. Respect -

@maluell738 Жыл бұрын

Thank you very much Dr. Peng for the very useful lecture. From my own experience Glucosamine /Chondroitin as long term supplement helped me in summer months. Unfortunately, I suffer from extreme pain during Autumn/Winter season. So I tried with Hyaluron injection once a week all in all 5x to which the Orthopedic told me I can have up to 10 injections yearly. To date I have none or just tolerable pain during Autumn/Winter time.And that saved me to date from having artificial knee joint.

@JeffreyPengMD Жыл бұрын

Awesome, thanks for sharing

@maluell738 Жыл бұрын

@@JeffreyPengMD I thank you Dr. Peng. I gained additional knowledge following your Vlogs. 👍👏

@abradfordajb Жыл бұрын

I'm presently using a product from Solgar which combines, in 3 daily tablets, the recommended mg levels of these two nutrients, integrated with 1,500 mg MSM & 300 mg of their formulation of "Biocell Collagen II" (180 mg Hydrolyzed Collagen II, 48 mg Chondroitin Sulfate, 30 mg Hyaluronic Acid). I also drink a daily scoop of a collagen peptide powder mixed in water. My objective is focused on rebuilding cartilage rather than simply reduction in pain. Knee cartilage destruction results in damage to the meniscus. In theory the meniscus can heal, but degenerated cartilage will just continue to "grind" the meniscus like sand paper. So, the goal is to reduce degeneration of cartilage. I plan to continue on this formulation for 1 year and see where it takes me. My knee arthritis does not produce chronic pain, though most days low to moderate discomfort. I am 70 yo and exercise consistently including a return to measured weekly running. I am interested in reading your thoughts on this regimen. Thanks for your informative posts .... much appreciated.

@JeffreyPengMD Жыл бұрын

Thanks for sharing!

@SKs. Жыл бұрын

Good video. Extremely informative. Thank you

@faridasukra8570 10 ай бұрын

Thank you so much ❤

@sionitacarnen9053 Жыл бұрын

Thanks immensely this beneficial video. Helpful . ❤

@JeffreyPengMD Жыл бұрын

Glad it was helpful!

@sable2146 6 ай бұрын

4:13 started taking a glucosamine and chondroitin for joint achiness a few years back and definitely noticed they have a delayed which is easy to overlook both going on and coming off (about effect 3-5 days for me). That these also act to address inflammation helps me to put in perspective why they work for me.

@lopezb 6 ай бұрын

Yes, agreed. G and C with HA and collagen, the last 2x-day. Right hip pain almost gone. Still cant sit lotus position, but now I walk 40 min/ day with no pain. Initially 1 year ago I couldn't walk 1 step w/o pain, and was taking acitaminophen to sleep- which is terrible for liver.

@StephenfromChch Жыл бұрын

Very helpful.

@briansmale5457 10 ай бұрын

I've tried just about everything known to Man without much success, i then tried Green Lipped Mussel from NZ & have found a great improvement :) I gave everything i tried 12 weeks & if i didn't feel any improvement i moved on to another supplement, the green lipped musssel showed improvement with in a few weeks. I've been taking it for about 2 years now & i have to say i'm really impressed with the results.

@readthebook55 Жыл бұрын

Thanks for this helpful information.

@JeffreyPengMD Жыл бұрын

You're welcome!

@raymondlanier1112 6 ай бұрын

This supplement saved my life

@Desperado3248 7 ай бұрын

I was skeptical at first, as a physician. I tried a short course of Glucosamine / Chondroitin in the past with little relief. I had been active, going to gym, hiking , martial arts and work. Sudden onset of arthritis in my k red was extremely painful. Tried nsaids, then knee injections with steroid once then two injections with hyaluroninase gel. First gave some improvement. Wore off in a few weeks. Second was not terribly successful, needed, nsaid. Started combination Glucosamine/Chondroitin and relief started in about 3 weeks, and is better entering my second month. I am walking, with my dog which was difficult, not getting pain at rest bit driving, can do more squats and horse stance posture workouts , and able to perform martial arts kicking again. A study looking at poor response from gel with addition of Glucosamine/Chondtoitin. I was looking at knee replacements , which now do not appear to be necessary. I will follow up with repeat k we c rays to see what status of arthritis changes are

@Sirrehpotsirch 2 ай бұрын

I'm encouraged by your post! It's been four months. Care to report on your progress? Still positive about G and C? Thanks.

@gcea123 Жыл бұрын

My own independent study over past 10 + years. Glucosamine Chondroitin MSM helped my knees but not my hip.

@keithbutcher5386 2 ай бұрын

I take turmeric, glucosamine, chondroitin. All help my OA, but just started on Hyaluronic Acid. Results are stunning.

@harjitkaur5407 Жыл бұрын

I have been having knee pain..later diagnosed as osteoarthritis for almost a decade. The doctor suggested surgery but I did my own research on what is effective for me.. Collagen, omega 3, boswellia with turmeric and pepper besides glucosamine + chondrotine +MSN.. Very very effective for me.

@JeffreyPengMD Жыл бұрын

Thanks for sharing

@revathik9225 7 ай бұрын

@harjitkaur5407 which brands do you use?

@harjitkaur5407 7 ай бұрын

@@revathik9225 swissmed omega plus 1000mg , Himalaya shallaki (boswellia),

@rit20095 5 ай бұрын

Which brand r u taking?

@harjitkaur5407 5 ай бұрын

@@rit20095 as of present I am only taking boswellia Himalaya brand and omega 3. Omega Plus Swiss med . Has cut down on the rest of the supplements. Now maintaining with only those two.

@brianbanks3044 6 ай бұрын

i take both Gluc and Chon and Syn Flex for 20 yrs...I stopped the synflex for a month and my knees started hurting...guess what, I went back on synflex and all the pain went away....I will take both for the rest of my life

@Rosebie88828 5 ай бұрын

I agree with you doc base of my experience

@MadDawg-bp5wt 7 ай бұрын

The first study mentions was has no effect on 'short term' pain and function, the other studies appear to look at a longer view .... glucosamine & chondroitin is a long term play. After years of knee pain (not arthritis) it took a few months of glucosamine and chondroitin for the pain to leave, and function improve.

@newyorkguy158 Жыл бұрын

My story is interesting. I was developing OA in my right hip from the mid 1990's on, but I thought it was a muscle problem. The pain was never in the hip, but in the inner thigh. By 2001, I was in severe pain and limping badly. A rheumatologist diagnosed mild to moderate OA and said I would need a hip replacement within 5 years. He asked me if I wanted a referral to a surgeon. I told him that I had just started to take glucosamine and wanted to see if it would work. Within a week of taking it, my pain was totally gone in all normal activities, sitting, walking, standing and sleeping. For the next 14-15 years, glucosamine worked for me, but not all brands. For example, the CVS brand did not work. During this entire period, I only experienced pain infrequently and then only for one to a few minutes. I felt normal. I would often sprint to catch a bus or race down the stairs to catch a train with no pain. I didn't always take glucosamine with chondroitin. Often, I took glucosamine by itself and it worked very well. I concluded that chondroitin was of no help for pain. Some of the products had proprietary ingredients like bromelain and other anti-inflammatories, but not all. I can't judge the effectiveness of the proprietary formulas, since they all contained glucosamine, 1500 mgs. The form of glucosamine did not matter. I want to emphasize that brand mattered. Glucosamine is a large molecule and you need a formulation that can be absorbed into the joint. You have to try things. My advice is to not go cheap. Some of the better products can run $40-50/month, but some in the $18-25 range worked equally well. There are often 2 for 1 sales with some products. Some products worked for a period of time like 2-3 years, then began to lose effectiveness. When that happened, I switched to other products and was lucky that several brands worked very well. After 14 years, I started to get some pain at times and none of the glucosamine products were left to try. I knew that I was going to need a hip replacement. I started to play sports again and sure enough I found myself in severe pain again, with no safe product to take. I got lucky though. I learned about hip resurfacing, a surgery in which the arthritis is fixed without removing the hip. I still have my original hip and it's strong enough to play any sport. I haven't had any pain since the surgery was healed. That was in 2018. Glucosamine can definitely work, though not necessarily for everyone, but you need to experiment with the brand. My experience was not unique. Also, it may work for the hip but not the knee, or vv. I would definitely do the exercises that Dr. Peng is demonstrating, and others. Thanks to Dr. Peng for this excellent video.

@narenmenon6906 10 ай бұрын

You must be using the "sulfate" form of the two. I also take MSM.

@user-qn8xe8os4x 2 ай бұрын

I have been taking Glucosamine on its own, which works really well for me. I don’t take Chondroitin as I have a bad reaction from it.

@michaelstagar525 Жыл бұрын

Excellent stats-peer review!

@JeffreyPengMD Жыл бұрын

Glad you liked it!

@shrinandan3458 Жыл бұрын

Dr. Peng, Thanks for a very informative video. My personal experience is that the two meds when combined with MSM are very beneficial. I'm a 78 year old male with a family history of osteoarthritis. MSM definitely adds to the effectiveness. More studies should be done with the trifecta. I am living proof that it works.

@JeffreyPengMD Жыл бұрын

Thanks for sharing

@kenhoward3512 10 ай бұрын

And the next question would be whether the chondroitin could be supplanted by MSM? I've been taking glucosamine with MSM for 23 years. As always: "More studies are needed..."

@revathik9225 7 ай бұрын

@shrinandan3458 Which brands of glucosamine and MSM do you use?

@brucetownsend691 7 ай бұрын

I have found taking the Kirkland brand Glucosamine Sulfate, Chondroitin and MSM works for me. I just take 2 tablets each night. If I stop this routine I start getting arthritic pain again, so I keep it up. (Before getting on to this combination, I was using just Glucosamine with good effect, provided it was the more expensive sulfate rather than the cheaper hydrochloride form.)

@saralakushwaha1180 10 ай бұрын

Thank You 👍👍👍

@gordner5686 Ай бұрын

I have switched to using Turmeric and ginger with Black pepper extract for my kneecap arthritis. I used to be in significant pain while using Glucosamine and Chondroitin. I now have minimal pain and I never feel the grinding in my kneecap.This improvement took place within the first week of use. I walk about 10 K a day. I am 66 years old.

@docJamesE1318 2 ай бұрын

Dr Peng thank you for your concise analysis. Joint pain relief outside of Opioids is necessary what is your recommendation. Many Arthritic and chronic joint pain patients are in need of something that is greater than placebo. Let me know.

@rameshnamdhe979 Жыл бұрын

Thanks for important information

@JeffreyPengMD Жыл бұрын

Welcome!

@visforvegan8 7 ай бұрын

Based on this, I'll continue to use it for my dog who's torn both his ACL's.

@cynthialorenzo9376 9 ай бұрын

That it works also for meniscus problem..

@Seija729 7 ай бұрын

helped with knee pain and back pain. i only take it when pain flares up so body doesn't become dependent, works every time.

@pauljmey 2 ай бұрын

One or both of those is known to block glucose uptake in the gut. People with metabolic disease typically have greater pain/burning sensations when exposed to sugar/carbs, so that's a mechanism that would apply depending on when you ingest relative to a meal.

@Keithmurray23 2 ай бұрын

I’ve been installing carpet for 30 years and my knees are pretty rough. I’ve been taking a supplement that has glucosamine, chondroitin and MSM. It’s the MSM that makes all the difference. When I take it I can go up and down steps virtually pain free and can run as well. I HIGHLY recommend it. It’s been a game changer for this lifelong carpet installer.

@mwilliams-castillo9609 Жыл бұрын

Great info thanks for sharing , my doctor told me to use that

@JeffreyPengMD Жыл бұрын

Glad it was helpful!

@georgehugh3455 6 ай бұрын

I took glucosamine and condroitin for my knees a decade ago and inexplicably started to get pain in both big toes. Tried it again (just two doses) two years ago and it happened again...and it lasted a long time. No mas.

@tlmqp1426 6 ай бұрын

Wow, that was a mouthful. Thanks for the vid. It would be also interesting and helpful to know the exercise and lifestyle habits of those in the study, as well as the use of G & C in terms of preventative benefits before any onset of osteopetrosis. People may not be incorporating these supplements and/ or a healthy diet and/ or an exercise regime into their routines. Rather, as in the scope of this video, G & C serve as a potential remedy to treat the effect of joint pain; whereas, these supplements may play important roles in preventing joint pain in the long term. If they do, which is likely, their effectiveness should be measured along with diet, exercise, age, and even hereditary factors. The premise here is supplements in the after-the-fact, rescue role, and we just aren’t supplied with the other variables. Sports medicine is about treatment of pain in part, but hopefully more so about investing in being and staying active, which is proactive.

@cynthiagonzalez658 6 ай бұрын

Hooray for those to whom G/C worked. Worked for me for a few weeks, then the pain all came back. BTW, same experience with Meloxicam so maybe my liver just is super active in discarding meds

@BradiKal61 6 ай бұрын

Started getting knee and joint pain in late 40s (after being put on statins for high cholesterol, and was told by friends that they felt statins were the problem). After stopping the statins mist of the effects seemes to decrease but not disappear. Doctor later recommended glucosamine & C) which Ive been on for almost 5 years and joint pain and weakness feels much better but I can't say my regimen is a guaranteed success. Thanks to Costco prices my G&C costs are low so I keep taking it. The recent discussion about unknown higher levels of microplastics in bottled water may explain a LOT of health issues and I hope THAT research ramps up immediately.

@user-ff9yk7ik2n 7 ай бұрын

As suggested the "multi model approach" in your other video, will Glucosamine & Chondroitin work fine along with PRP injections?

@delsisabarc5790 Жыл бұрын

GREAT RESULTS! After taking a supplement with Collagen+Glucosamine+Chondroitin for 2 years, I have experienced much less pain, most of the time no pain at all, AND my MRI shows my osteoarthritis has reverted from an initial painful Stage-4 to a now easy-to-manage Stage 1. My doctor says this is not the same for everyone, but my body responded well. -- BTW: I took “Carticure Plus” (by a Spanish pharmaceutical): containing 5000mg Collagen (Bioactive Peptides), 1500mg Glucosamine hydrochloride, 1200mg Chondroitin sulfate, Copper, Vitamin C, Manganese. It’s an orange flavored powder you mix with water. As per Dr instruction: I took 1/day for the first 6 months, then 1 every-other-day forever. It has rebuilt my cartage, or maybe just allowed by body to do what it was meant to do.

@JeffreyPengMD Жыл бұрын

Thanks for sharing

@inhalingexhaling1852 Жыл бұрын

Hi, great to hear your experience. Did you have knee osteoarthritis ? and whats your age, if i may ask? My mom has been diagnosed with knee osteoarthritis grade 2-3 almost. she is not experiencing that much pain but movement walking time is restricted to very limited, because of discomfort and slight pain. Doctor prescribed "cartibless" supplement which has collagen glucosamine chondroitin vitamin c hyaluronic ingredients and multi vitamin supplemetnts. she is taking for almost 1.5 months. I would love to hear how you did it or your journey, what was your experience for 2 years. It could really help us understand how to deal with it. she is just 53. Thanks

@delsisabarc5790 Жыл бұрын

@@inhalingexhaling1852 Yes, I have osteoarthritis in both knees + meniscus tear in right knee. I am 61 years old. I force myself to walk 1 hours/day (3-6 km), this is key to move the joint so it lubricates well. I stopped taking Carticure for a few months last year (arrogantly thought I was "cured"), & the pain came back with a vengeance, could only walk very short distances. I went back on Carticure and after 2 months was again pain-free, however, I did have to incorporate strength training + daily stretching since I could not walk very much for a while. At my age it's surprising how quickly one loses muscle strength!

@juri_mjatlin Жыл бұрын

From stage 4 to stage 1. Is it real?

@inhalingexhaling1852 Жыл бұрын

@@delsisabarc5790 oh nice. good to hear you are doing well with this. I also think movement, walking is the key here with supplements and physiotherapy or chiropractor. Because that helped my mother from getting exhausted now, able to walk without any discomfort. Thanks for sharing, Do update on it. Maybe we all can learn and grow from each other experiences.

@lynettamurdoch5443 7 ай бұрын

I used to take the combined glucosamine/chondroitin, but then read that the one of them - I don’t remember which one - made no difference in studies so I quit and started taking MSM/chondroitin(?). Eventually, I started taking only the MSM. I really don’t notice much difference with any of the combinations - or when used alone and may quit. I do take the fish oil, or krill oil. I think it helps - but mostly, my first noticeable difference was in my thinking/brain. Lately, I’ve discovered red light therapy and I’ve been using a band that wraps around my back, hip or knees, and recently, my shoulder. It has made the most noticeable difference.

@phyllissirois2118 5 ай бұрын

I will try ty

@robohippy 6 ай бұрын

Prior to getting bilateral hip replacement and one knee replacement, I tried several different brands of each of clucosamine and chondritin, and as far as I could tell, they didn't do anything to relieving joint pain. It was long enough ago that I don't remember if I tried them together. There could be multiple reasons for them not working, including how severe my issues were.

@retiredlogman 7 ай бұрын

It works for me. It takes a few weeks initially to feel the difference. User of over 30 years. Study has ended.

@johnmontana4898 10 ай бұрын

I've been taking it for almost 30 years.the hyaluronic acid. Keeps my skin from wrinkling. I'm 73 years and of course. You gotta exercise. I do some running also.

@Omegawerewolfx 5 ай бұрын

For my knee I do mobility exercises and strength training. My diet is pretty high on anti inflammatory foods too. Still have some bad days but I'm doing good. I'm not one of the people just popping pills and then claiming they work without any data.

@chirho777 2 ай бұрын

I've been taking thorne joint support nutrients with glucosamine and msm with curcumin, bromelain and boswellia but now will be buying thorne glucosamine & chondroitin and try that out. Haven't really noticed a difference with the support nutrients as I was just told I have mild arthur and ostio. I exercise regularly. 🙏🏽

@Dorisdani 8 ай бұрын

Thank you

@user-fh4xq2ig7z 6 ай бұрын

30 years ago I tore my ACL and got a classic bucket handle meniscus tear which was shaved smooth. Surgeon warned me I would have osteoarthritis there within 20 years. At year 19, the grinding started (great prediction by surgeon!). After confirming the arthritis with my doctor, I started taking glucosamine and chondrointin, but at 1/2 the recommended dosage. Within 6 months, the grinding went away and stayed quiet for 8 years. I did stop running (switched to cycling) and high impact exercises (I now teach indoor cycling and pilates). I did an accidental experiment when I tried to save money by buying gluchosamine without the chondrointin. Within 2 weeks, I had sharp pains start, so I added the chondrointin back, and the pain diminished within a month. I have now doubled my dose (which is the normal recommended daily dose) to maintain relatively pain-free living (as long as I avoid fast movements and high impacts). The combo really works! Are higher dosages than the recommended daily dosage safe?

@dcspangler8025 9 ай бұрын

Thank you for this post. I see that, along with the Glucosamine/Condroitin (G/C) some combinations include Methylsulfonylmethane (MSM). So how does this alter the equation? The majority of these supplements are manufactured using shellfish. There are some that are shellfish free, created by fermentation, I believe of corn. Further, what roll do GMO foods play? Both in causing inflammation in the first place and how the supplements manufactured with them differ in outcomes. Lastly, what about all the "other" ingredients? Magnesium stearate. stearic acid, etc. and how could they possibly alter the findings?

@thebrowns5337 6 ай бұрын

Microplastics and particle pollution - something we all have and cannot limit exposure to, lead to chronic inflamation. These have been found in umbilical cords so pass from mothers lungs into babies blood. We are setting ourselves up for shorter lives with more suffering. Ditching plastic and fossil fuels is needed to help our grandchildren.

@Earthstein 5 ай бұрын

Thanks Doc. Very helpful to me. Mr 71yo .

@ytujackclough 2 ай бұрын

It worked for me!

@landoan4719 6 ай бұрын

Thanhks Dr❤

@marilynroper5739 9 ай бұрын

I knew after 1 bottle that I would be using this. I’m sure it helps that I’m low carb and do strength training 6 days a week.Thanks for the detailed review, Dr Peng!

@boonkailee8237 9 ай бұрын

Hi doctor, please advise can i take glucosamine (include MSM & chondroitin) and boswellia together?

@TheHypercarnivoreChef 2 ай бұрын

I was taking NAC for some flue symptoms and it fixed my knees, so now I'm taking NAC everyday and my knees are back to a 20 years old athletic guy

@vijjreddy 2 ай бұрын

YES, IT CAN'T GIVE IMMEDIATE RELIEF, BUT VERY EFFECTIVE IN LONG TERM, AND ONE WILL EXPERIENCE ITS EFFECTIVENESS IF ONE STOPS TAKING THEM ON DAILY BASIS FOR A WEEK OR TWO, THE ARTHRITIS PAINS COME BACK

@jeanwang2475 10 ай бұрын

Hi Dr. Peng, I'm 61 now, after I seen the video, I'm curious to know if it's the right thing for me to take. When I go up or down the stairs, my knees are painful, and as I walked too long it's also in pain

@Commiefornia 6 ай бұрын

Beginning in my 40s my right knee didn't have pain but rather felt loose. When I stressed it, like running for a just a very short distance it would again, not hurt but felt even "looser". When going down steps it would pop when I bent that knee. I knew I needed to do something or I was going to eventually have to do knee replacement. I began taking a shellfish based liquid glucosamine/condroitin/MSM and I began feeling a positive change. I tried other types of powder glucosamine and eventually I would have the same loose feeling in my knee. I went back to the shellfish based liquid glucosamine and my knee would get better. I concluded that shellfish is the best source of glucosamine if you're not allergic. I've been taking a shellfish based gummy glucosamine/condtroitin/MSM supplement and it's been working just as well as the liquid, but I don't have to worry about refrigeration.

@smarzig 4 ай бұрын

what brand?

@Commiefornia 3 ай бұрын

@@smarzig I was using Flexicose. But when my old fridge stopped working a couple times causing me to dump a couple of opened bottles I switched to gummy glucosamine since they don't have to be refrigerated.

@larrym2434 6 ай бұрын

The cited study said specifically, "in the short term." I think a completely different, and more relevant question is, "Does glucosamine chondroitin help in the long term with consistent use?" In my experience, it doesn't help much in the short term, but IT DOES HELP when taken consistently in the long term.

@lisag18 7 ай бұрын

I took this for many years then i started using fish oil. I feel a lot better overall. Fish oil helps with everything, not just achiness and arthritis. It helps the body as a whole. Curcumim is good, too

@abrianec 2 ай бұрын

There is a big difference between repairing a damaged joint and maintaining joint health over the long term, many studies have focused on short term repair and many are very poorly designed using vague metrics- one widely reported study used vague measures of patient evaluated discomfort in patients with serious joint damage over a short period. Many people I know take supplements for maintenance and inflammation reduction- these are very active people with osteoarthritis. I take glucosamine/chondroitin/ASU as formulated by Dr Theodakis who claims clinical evidence for ASU is stronger than for G -C, even given clinically demonstrated benefits of G-C. I haven’t seen much on ASU in the popular media.

@dannydelatorre7122 11 ай бұрын

I have had DDD in one of my lower back discs, and last Sunday I had a massive flare up. I had extreme pain and could not stand up straight, couldn’t sleep well, and could not walk normally or even bend over without pain. The first morning following the day I took glucosamine and Chondroitin, my pain is basically gone. The pain level went from a 10 to a 2.

@vineysharma8245 9 ай бұрын

How are you doing now ?

@Beau1990 7 ай бұрын

I have DDD too and this gives me hope.

@garrynorth6199 7 ай бұрын

How much G/C were you taking, I’ve just started taking 2 capsules a day for my osteoarthritis and hoping it helps after a few weeks.

@ryanyunuss572 6 ай бұрын

Hi so recently, i started feeling a low back pain untill i figure it out it was my sciatica never and my friend whos a personal trainer advised me to take msm glucosamine + magnesium + amino acids, fun fact i started yesterday and was i was feeling pain yesterday at night, today i woke up with a almost no pain 😅 its crazy but its true, i will keep taking it and see how i feel in the next few weeks

@sonjanordahl3158 6 ай бұрын

I found that my body does not make good use of glucosamine but I do get results with glucosamine sulfate. I had been using glucosamine sulfate for a couple of years and it seemed to help. Then over about a 3 week period it seemed to have stopped working. I starred looking to see what was up and realized I had purchased glucosamine rather than the glucosamine sulfate I normally bought.