how can you not love Kathy Griffin? woman is amazing. Not to mention hysterical.

"I make fun of Ryan Seacrest. And she doesn't always take it that well". Ha ha, too funny

Just came back from her show in Boston. She rocked the packed therater like a boat! Awesome lady!!! Love her!!!

Life on the D List was a great show.

I've never seen him laugh so much

She is legitimately funny

She is wonderful

best interview ever

i fucking love kathy! shes so fucking funny, i cant wait to read her book

hahah dave is just laughing his ass off, doesnt even have to say anything :P

now if she could do the white house correspondents dinner.

One of the few consistently funny comedians out there. But it seems you either love her or hate her. I think you rock Kathy!

Kathy's so pretty and funny. I love how she subtly defends david with her anti-Palin jokes. I just adore her.

She looked great here oml

Kathy Rocks!!! Sadly, not everyone gets her sense of humor. Well, that makes her even more special!

This woman is hysterically funny and quick!

I make fun of Ryan Seacrest and SHE doesn't always take that well!! LMAO

God Bless Kathy! I love her, she's the best! Every word that comes out of her mouth makes my day! :)

This was comic gold...Letterman & Kathy are both brilliant & sharp as a whip!

She is hilarious

So sad that this is Kathy's last year for the D List. She's the best!

that was a great interview. she is hilarious!

Kathy is a true gem!

That was so cool! They got along really well. Hope he has her on again.

thank you so much for posting!

Kathy was on her game in this interview but I've seen her really bomb in her stand up routines. I personally like her and find her funny the majority of the time.

Those 2 go so good together!!! But Kathy is my hero!

Love these 2 together

I love Kathy, she is smart funny

kathy is soooooooo funnny! i love her! her show is great too, it's my new favorite.

Loved this appearance. I didn't know what happened ot Dave for years but.... " what have you been doing?"...lol

I lol'd a bit inside when I heard the "here's the lovely" part.

She has so much energy!

this women is great! shes hilarious

LOVE KATHY!!!!!!!!!!

hilarioussssss

fantastic interview - im sure she will be back. dave seemed to really enjoyed her.

LOVE HER!

i adore kathy

I heart Kathy!

Kathy you killed and Dave is funny as always.

love this hair on her

Great interview!

Great interview.

This must have been her first time back after the ban.

she's absolutely the best!

"ive made fun of Ryan Seacrest and SHE doesn't always take it that well" HAHA. Love that Part.

comediennes don't get sharper than our dear kathy...

love Kathy! she is just fearless!

Omg Paul did not cut in once during the interview! ! ! Kathy, rox my jox - always nails her interviews.

I have a hot/cold reaction to Kathy. Just after she cracks me up, she irritates and so it continues. But I LOVED her description of Katie Couric as a scrappy 'little person' ala 'Small people, big world'. Hilarious. And her Oprah digs. Funny too.

It was a great interview I hope this make the round on the blogs, so more people watch this season of the d-list... The fist episode was great!!

i love her!!! :D and she always cracks me up! :P

I like her, always have. She's spunky :)

Kathy, you make me laugh. Thanks.

She made jokes about so many things that have since come to light. 😮 Smart and witty woman with great intuition

A natural

love kathy!

she's HILARIOUS!!!!!! i LOVE her show!!!!!!! and yall need to stop getting upset because she's speaking her mind!!!!!!! most the things she says are true!!!!!!!! and yea! she got MEGA MEGA BALLS!!

she's hilarious

LUV HER

love her!

Just one question to MangoVisionHD What does the "HD" stand for if the video doesn't have a HD option? /puzzled

I love her!

say what you what want about her looks, but she is undeniably funny.

yeh!!!!! kathy griffin finally on letterman love them both

sure I'll watch

i couldn't stand her when i first saw her, but she really grows on you. i LOVE her now!!

i love her!

oh kathy, what a crowd pleaser

God Bless her beautiful heart

she's so damn funny! lololol!

I LOVE HER 💛💛💛 so funny

Kathy is BRILLIANT and the BEST comedienne in America. and looks GREAT! Luv her, the only one out there not afraid to tell the truth.

Yes. It currently is holding steady. We're not free falling anymore. I'm speaking from the business point of view, as I'm a business owner. 'unemployment rates' This is nothing new. These rates are no worse than they were in the 70's and 80's. The thing that is different, is that this is a lingering recession. But it feels like it's turning around, slowly.

neat

I like her. She has mega balls!

Wow.......you might be the most insightful person on You-Tube!

brillant sarah pailn is insaine

fransia is her jam .....lol, poetry!!

kathy is so funny

7:56 i’m laughing so hard at Kathy that tears are falling from my eyes… Yet, the audience seems uncertain. That’s Kathy!

Oprah Winfrey thinks she's jesus reincarnated, every joke she has totally coming, Kathy is just funny, and she makes fun of everyone including herself a lot, so don't take it so seriously. She loves her dogs, you never saw her D-List show?

I think David really enjoyed having her on the show! Prior to her appearance Kathy twittered that the ban had been lifted, so apparently she was not allowed to be on the show after something she must have said during her last appearance...

well said.. :]

💖💖💖💖💖💖💖David 💖💖💖💖

I think I saw her on Family Guy. She's married to a guy named Peter.

i love her i think that she is realy funny

Kathy was banned from many talk shows. However, once she started becoming a bigger star and winning awards they slowly started inviting her back. Only a matter of time before she's back on The View....

You're done with David Letterman? wow,he must be devastated.

They all bomb and they all admit it.

It's a joke.. She's a comedian...

Wow. Good insane rambling here. Go Letterman!

The economy is stablilized? Are you sure about that? We were told unemployment would go no higher than 8.5%; now its heading towards 9.4% and rising. Nothing has been stabilized.

kathys my girl....

Oh so this is why she got those Oprah wanting to kill her vibes..lol! She messed with mama Angelo!! I see now..lol!

😂😂😂😂😂😂😂😂😂

she is right about sarah palin and her husband

Kathy fancies David! Kathy likes good ole David!! 🙊

Nice facelift Kathy. Does the rubberband on the back of your head that helps keep your face real tight come off at night? Or do you sleep with it on?